Beilstein J. Org. Chem.2012,8, 1884–1889, doi:10.3762/bjoc.8.217
China 10.3762/bjoc.8.217 Abstract A new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4
; cytotoxicity; Selaginella tamariscina; selaginellin; Introduction
There are about 700 species of the genus Selaginella (family selaginellacea) widely found in the world, with more than 50 species being found in China [1]. Twenty of them are widely used in Chinese folk medicine, most frequently employed for
]. Selaginellin derivatives have been hitherto found only in genus Selaginella. In the course of our phytochemical investigations on Selaginella tamariscina (Beauv.) Spring, four selaginellin derivatives (Figure 1), namely selaginellin M (2) [20], selaginellin (3) [13], selaginellin A (4) [14], and a new analogue
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Graphical Abstract
Figure 1:
Structures of selaginellins from S. tamariscina.