Beilstein J. Org. Chem.2019,15, 2029–2035, doi:10.3762/bjoc.15.199
.
Keywords: benzimidazole; cesium carbonate; cyclization; selenium; selenoazole; Introduction
Selenium-containing heterocyclic ring systems have attracted attention not only because of their chemical properties and reactivities, but also for their wide biological activities [1][2][3][4]. For example
, imidazo[2,1-b]selenoazoles, in which imidazole and selenophene are condensed, have been synthesized, and it was described in a patent that imidazo[2,1-b]benzoselenazole-3-acetamide derivatives have anticonvulsant activity [5]. Three ring closure reactions for the synthesis of imidazo[2,1-b]selenoazole
PDF
Graphical Abstract
Scheme 1:
Previously reported synthetic methods for the preparation of imidazo[2,1-b]selenoazoles.