pH-Responsive fluorescent supramolecular nanoparticles based on tetraphenylethylene-labelled chitosan and a six-fold carboxylated tribenzotriquinacene

• Nan Yang,
• Yi-Yan Zhu,
• Wei-Xiu Lin,
• Yi-Long Lu and
• Wen-Rong Xu

Beilstein J. Org. Chem. 2023, 19, 635–645, doi:10.3762/bjoc.19.45

• stimulus-responsive supramolecular vesicles and molecule-scale drug carriers are considered to have potential for cancer drug delivery. However, such supramolecular systems are not suitable for oral administration, which is a convenient and patient-preferred method of drug delivery, especially for patients

Using multiple self-sorting for switching functions in discrete multicomponent systems

• Amit Ghosh and
• Michael Schmittel

Beilstein J. Org. Chem. 2020, 16, 2831–2853, doi:10.3762/bjoc.16.233

• reconfigurable self-sorting is a protocol that Nature efficiently uses when responding to external stimuli [32]. The development of stimulus-responsive transformations between the supramolecular assemblies is a significant challenge in chemistry, in particular in regards to realizing biomimetic functions [33

Size-controlled and redox-responsive supramolecular nanoparticles

• Raquel Mejia-Ariza,
• Gavin A. Kronig and
• Jurriaan Huskens

Beilstein J. Org. Chem. 2015, 11, 2388–2399, doi:10.3762/bjoc.11.260

• their use as drug delivery vehicles. Here, we aim to form supramolecular nanoparticles (SNPs) by combining advantages of the reversible assembly properties of SNPs using host–guest interactions and of a stimulus-responsive moiety. The SNPs are composed of a core of positively charged poly(ethylene imine

• core of the SNPs. Keywords: host–guest interactions; nanoparticles; self-assembly; stimulus-responsive; supramolecular chemistry; Introduction Self-assembly and molecular recognition are two core concepts underlying supramolecular chemistry. These offer convenient and versatile pathways to

• charged polymers and dendrimers. In order to use these SNPs for biomedical applications, in particular for drug delivery, a stimulus-responsive self-assembled system is desired for controlled cargo release. Ferrocene (Fc) is a ubiquitous redox-responsive molecule that is associated with a reversible one

Preparation and evaluation of cyclodextrin polypseudorotaxane with PEGylated liposome as a sustained release drug carrier

• Kayoko Hayashida,
• Taishi Higashi,
• Daichi Kono,
• Keiichi Motoyama,
• Koki Wada and
• Hidetoshi Arima

Beilstein J. Org. Chem. 2014, 10, 2756–2764, doi:10.3762/bjoc.10.292

• various targeting-ligands such as antibodies, sugars and folic acid to LPs [30][31][32]. Recently, stimulus responsive LPs such as bubble LPs, pH responsive LPs and thermoresponsive LPs have been developed as smart drug carriers [33][34][35]. PEGylated LP (PEG-LP) is one of the most popular LP products

Functionalized polymers: synthesis and properties

• Helmut Ritter

Beilstein J. Org. Chem. 2010, 6, No. 55, doi:10.3762/bjoc.6.55

• fillings, wound dressings, bone cements or hollow fibers for dialysis. Typical examples of such materials include hydrogels and stimulus-responsive polymers which are also the basis of ophthalmic surgery. Thus, our aim in this Thematic Series is to bring together a broad spectrum of reports in the field of