Interactions at the cell membrane and pathways of internalization of nano-sized materials for nanomedicine

Valentina Francia, Daphne Montizaan and Anna Salvati
Beilstein J. Nanotechnol. 2020, 11, 338–353. https://doi.org/10.3762/bjnano.11.25

Cite the Following Article

Interactions at the cell membrane and pathways of internalization of nano-sized materials for nanomedicine
Valentina Francia, Daphne Montizaan and Anna Salvati
Beilstein J. Nanotechnol. 2020, 11, 338–353. https://doi.org/10.3762/bjnano.11.25

How to Cite

Francia, V.; Montizaan, D.; Salvati, A. Beilstein J. Nanotechnol. 2020, 11, 338–353. doi:10.3762/bjnano.11.25

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 394.3 KB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Greco, A.; Imperlini, E.; Lee, G. Y.; Serda, M.; Tobar Leitão, S. A.; Corbo, C. Study of the biomolecular corona of surface-modified polystyrene and silica nanoparticles: application to cancer. Nanoscale 2025, 17, 25254–25265. doi:10.1039/d5nr03082j
  • Dobricic, M.; Martinez-Serra, A.; Durall, C.; Nakonechna, A.; Cheeseman, J.; Preston, R.; O'Donnell, J. S.; Spencer, D. I. R.; Aastrup, T.; Monopoli, M. P. Terminal sialic acids in the nanoparticle corona modulate cellular uptake. Communications chemistry 2025, 8, 308. doi:10.1038/s42004-025-01677-x
  • Tabolacci, C.; Batani, G.; Rossi, S.; Andrei, D.; Bellenghi, M.; Pedini, F.; Mischiati, C.; Scattoni, M. L.; Biffoni, M.; Facchiano, F.; Ferreri, C.; Sansone, A. Capsaicin and Its Combination with Oleic Acid Affect Membrane Fatty Acid Remodeling and Cytokine-Chemokine Secretion in HepG2 Cells. International journal of molecular sciences 2025, 26, 8242. doi:10.3390/ijms26178242
  • Alvarez-Quezada, O. A.; Arellano-Rodríguez, N. C.; Rodríguez-Rodríguez, M. V.; Franco-Molina, M. A.; Zarate-Triviño, D. G.; Zamora-Ávila, D. E.; Vargas-Requena, C. L.; Zapata-Benavides, P.; Rodríguez-Padilla, M. C. Encapsulation of Curcumin and Gemcitabine: Cytotoxic Effect and Mechanisms of Death in Lung Cancer. Advances in pharmacological and pharmaceutical sciences 2025, 2025, 8816364. doi:10.1155/adpp/8816364
  • Samal, P.; Satpathy, S.; Panigrahi, L. L.; Jha, S.; Arakha, M. Exploring the intricacies of protein-nanoparticle interaction and its implications in chronic diseases: a comprehensive review. Nanoscale horizons 2025, 10, 1615–1641. doi:10.1039/d5nh00076a
  • De Caroli, M.; Carrozzo, S.; Tornese, R.; Rampino, P.; Baldassarre, F.; Ciccarella, G.; Semeraro, T.; Piro, G.; Lenucci, M. S. Evidence of nanoCaCO3@PAE internalization in tobacco. Plant physiology and biochemistry : PPB 2025, 227, 110136. doi:10.1016/j.plaphy.2025.110136
  • Premcheska, S.; Skirtach, A. G.; Kaczmarek, A. M. Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers. Advanced NanoBiomed Research 2025, 5. doi:10.1002/anbr.202500003
  • Akhtar, S.; Zuhair, F. Advancing Nanomedicine Through Electron Microscopy: Insights Into Nanoparticle Cellular Interactions and Biomedical Applications. International journal of nanomedicine 2025, 20, 2847–2878. doi:10.2147/ijn.s500978
  • Li, M.; Li, N.; Piao, H.; Jin, S.; Wei, H.; Liu, Q.; Yu, J.; Wang, W.; Ma, S.; Jiang, Y.; Yao, H.; Shen, Y.; Fu, J. Nanomaterials for targeted drug delivery for immunotherapy of digestive tract tumors. Frontiers in immunology 2025, 16, 1562766. doi:10.3389/fimmu.2025.1562766
  • Sevarika, B.; Capri, D.; Frey, J.; Dinamarca, M. C.; Häussinger, D.; McNeil, S. Mannose-6-phosphate-PEG-lipid conjugates improve liposomal uptake. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2025, 209, 114665. doi:10.1016/j.ejpb.2025.114665
  • Liu, X.; Liu, X.; Luo, X.; Zhu, M.; Liu, N.; Li, J.; Zhang, Q.; Zou, C.; Wu, Y.; Cao, Z.; Ma, S.; Wang, W.; Yang, G.; Gu, J.; Liu, W.; Li, M.; Yin, A.; He, Y.; Lin, W. Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade. Journal of nanobiotechnology 2025, 23, 94. doi:10.1186/s12951-025-03112-8
  • Li, J.; Zhang, G.; Li, G.; Zhang, J.; Yang, Z.; Yang, L.; Jiang, S.; Wang, J. Harnessing nanoparticles for reshaping tumor immune microenvironment of hepatocellular carcinoma. Discover oncology 2025, 16, 121. doi:10.1007/s12672-025-01897-6
  • Haghighi, E.; Abolmaali, S. S.; Dehshahri, A.; Mousavi Shaegh, S. A.; Azarpira, N.; Tamaddon, A. M. Navigating the intricate in-vivo journey of lipid nanoparticles tailored for the targeted delivery of RNA therapeutics: a quality-by-design approach. Journal of nanobiotechnology 2024, 22, 710. doi:10.1186/s12951-024-02972-w
  • Olivieri, P. H.; Assis, I. F.; Lima, A. F.; Hassan, S. A.; Torquato, R. J. S.; Hayashi, J. Y.; Tashima, A. K.; Nader, H. B.; Salvati, A.; Justo, G. Z.; Sousa, A. A. Glycocalyx Interactions Modulate the Cellular Uptake of Albumin-Coated Nanoparticles. ACS applied bio materials 2024, 7, 7365–7377. doi:10.1021/acsabm.4c01012
  • Pant, A.; Laliwala, A.; Holstein, S. A.; Mohs, A. M. Recent advances in targeted drug delivery systems for multiple myeloma. Journal of controlled release : official journal of the Controlled Release Society 2024, 376, 215–230. doi:10.1016/j.jconrel.2024.10.003
  • Sousa Ribeiro, I. R.; da Silva, R. F.; Domingues, R. R.; Leme, A. F. P.; Cardoso, M. B. Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids. Beilstein journal of nanotechnology 2024, 15, 1238–1252. doi:10.3762/bjnano.15.100
  • Öztürk, K.; Kaplan, M.; Çalış, S. Effects of nanoparticle size, shape, and zeta potential on drug delivery. International journal of pharmaceutics 2024, 666, 124799. doi:10.1016/j.ijpharm.2024.124799
  • Sun, Y.; Zhou, Y.; Rehman, M.; Wang, Y.-F.; Guo, S. Protein Corona of Nanoparticles: Isolation and Analysis. Chem & bio engineering 2024, 1, 757–772. doi:10.1021/cbe.4c00105
  • Munafò, I.; Costa, D.; Milano, G.; Munaò, G. Absorption of Polypropylene in Dipalmitoylphosphatidylcholine Membranes: The Role of Molecular Weight and Initial Configuration of Polymer Chains. The journal of physical chemistry. B 2024, 128, 9905–9916. doi:10.1021/acs.jpcb.4c05035
  • Hasani, S.; Sadat Shandiz, S.; Pakpour, B. Cytotoxicity and Apoptotic Effects of Selenium Nanoparticles Toward HT29 Colon Cancer Cells. Cell and Tissue Journal 2024, 15, 190–202. doi:10.61186/jct.15.3.190
Other Beilstein-Institut Open Science Activities