Key for crossing the BBB with nanoparticles: the rational design

Sonia M. Lombardo, Marc Schneider, Akif E. Türeli and Nazende Günday Türeli
Beilstein J. Nanotechnol. 2020, 11, 866–883.

Cite the Following Article

Key for crossing the BBB with nanoparticles: the rational design
Sonia M. Lombardo, Marc Schneider, Akif E. Türeli and Nazende Günday Türeli
Beilstein J. Nanotechnol. 2020, 11, 866–883.

How to Cite

Lombardo, S. M.; Schneider, M.; Türeli, A. E.; Günday Türeli, N. Beilstein J. Nanotechnol. 2020, 11, 866–883. doi:10.3762/bjnano.11.72

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 651.9 KB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Naik, B.; Sasikumar, J.; Das, S. P. From Skin and Gut to the Brain: The Infectious Journey of the Human Commensal Fungus Malassezia and Its Neurological Consequences. Molecular neurobiology 2024. doi:10.1007/s12035-024-04270-w
  • Sadique, F. L.; Subramaiam, H.; Krishnappa, P.; Chellappan, D. K.; Ma, J. H. Recent advances in breast cancer metastasis with special emphasis on metastasis to the brain. Pathology, research and practice 2024, 260, 155378. doi:10.1016/j.prp.2024.155378
  • Muolokwu, C. E.; Chaulagain, B.; Gothwal, A.; Mahanta, A. K.; Tagoe, B.; Lamsal, B.; Singh, J. Functionalized nanoparticles to deliver nucleic acids to the brain for the treatment of Alzheimer's disease. Frontiers in pharmacology 2024, 15, 1405423. doi:10.3389/fphar.2024.1405423
  • Galindo, A. N.; Frey Rubio, D. A.; Hettiaratchi, M. H. Biomaterial strategies for regulating the neuroinflammatory response. Materials advances 2024, 5, 4025–4054. doi:10.1039/d3ma00736g
  • Saleh, S. R.; Abd-Elmegied, A.; Aly Madhy, S.; Khattab, S. N.; Sheta, E.; Elnozahy, F. Y.; Mehanna, R. A.; Ghareeb, D. A.; Abd-Elmonem, N. M. Brain-targeted Tet-1 peptide-PLGA nanoparticles for berberine delivery against STZ-induced Alzheimer's disease in a rat model: Alleviation of hippocampal synaptic dysfunction, Tau pathology, and amyloidogenesis. International journal of pharmaceutics 2024, 658, 124218. doi:10.1016/j.ijpharm.2024.124218
  • Cogill, S. A.; Lee, J.-H.; Jeon, M.-T.; Kim, D.-G.; Chang, Y. Hopping the Hurdle: Strategies to Enhance the Molecular Delivery to the Brain through the Blood-Brain Barrier. Cells 2024, 13, 789. doi:10.3390/cells13100789
  • Forgham, H.; Zhu, J.; Huang, X.; Zhang, C.; Biggs, H.; Liu, L.; Wang, Y. C.; Fletcher, N.; Humphries, J.; Cowin, G.; Mardon, K.; Kavallaris, M.; Thurecht, K.; Davis, T. P.; Qiao, R. Multifunctional Fluoropolymer-Engineered Magnetic Nanoparticles to Facilitate Blood-Brain Barrier Penetration and Effective Gene Silencing in Medulloblastoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024, e2401340. doi:10.1002/advs.202401340
  • He, W.; Wang, N.; Wang, Y.; Liu, M.; Qing, Q.; Su, Q.; Zou, Y.; Liu, Y. Engineering Nanomedicine for Non-Viral RNA-Based Gene Therapy of Glioblastoma. Pharmaceutics 2024, 16, 482. doi:10.3390/pharmaceutics16040482
  • Li, Z.; Kovshova, T.; Malinovskaya, J.; Knoll, J.; Shanehsazzadeh, S.; Osipova, N.; Chernysheva, A.; Melnikov, P.; Gelperina, S.; Wacker, M. G. Blood-Nanoparticle Interactions Create a Brain Delivery Superhighway for Doxorubicin. International journal of nanomedicine 2024, 19, 2039–2056. doi:10.2147/ijn.s440598
  • Cai, J.-y.; Liu, Y.; Zhang, L.; Guo, R.-b.; Liu, Y.; Li, X.-t.; Ma, L.-y.; Kong, L. Menthol-modified paclitaxel multifunctional cationic liposomes cross the blood-brain barrier and target glioma stem cells for treatment of glioblastoma. Journal of Drug Delivery Science and Technology 2024, 93, 105387. doi:10.1016/j.jddst.2024.105387
  • Veselý, O.; Živný, M.; Nigríni, M.; Veselý, J.; Čejka, J. The effect of the active site and substrate structure in preparation of substituted tetrahydropyrans via intramolecular cyclization. Catalysis Today 2024, 429, 114465. doi:10.1016/j.cattod.2023.114465
  • Battaglini, M.; Marino, A.; Montorsi, M.; Carmignani, A.; Ceccarelli, M. C.; Ciofani, G. Nanomaterials as Microglia Modulators in the Treatment of Central Nervous System Disorders. Advanced healthcare materials 2024, 13, e2304180. doi:10.1002/adhm.202304180
  • Zha, S.; Liu, H.; Li, H.; Li, H.; Wong, K.-L.; All, A. H. Functionalized Nanomaterials Capable of Crossing the Blood-Brain Barrier. ACS nano 2024, 18, 1820–1845. doi:10.1021/acsnano.3c10674
  • Zhao, C.; Zhu, X.; Tan, J.; Mei, C.; Cai, X.; Kong, F. Lipid-based nanoparticles to address the limitations of GBM therapy by overcoming the blood-brain barrier, targeting glioblastoma stem cells, and counteracting the immunosuppressive tumor microenvironment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024, 171, 116113. doi:10.1016/j.biopha.2023.116113
  • Rathnam, S. S.; Deepak, T.; Sahoo, B. N.; Meena, T.; Singh, Y.; Joshi, A. Metallic Nanocarriers for Therapeutic Peptides: Emerging Solutions Addressing the Delivery Challenges in Brain Ailments. The Journal of pharmacology and experimental therapeutics 2024, 388, 39–53. doi:10.1124/jpet.123.001689
  • Kapoor, D.; Sharma, D.; Pathak, Y.; Prajapati, B. G.; Satani, B. Nanoformulations targeting Alzheimer's disease. Alzheimer's Disease and Advanced Drug Delivery Strategies; Elsevier, 2024; pp 265–282. doi:10.1016/b978-0-443-13205-6.00010-8
  • Chakraborty, P.; Bhattacharyya, C.; Sahu, R.; Dua, T. K.; Kandimalla, R.; Dewanjee, S. Polymeric nanotherapeutics: An emerging therapeutic approach for the management of neurodegenerative disorders. Journal of Drug Delivery Science and Technology 2024, 91, 105267. doi:10.1016/j.jddst.2023.105267
  • Verma, R.; Rao, L.; Nagpal, D.; Yadav, M.; Kumar, M.; Mittal, V.; Kaushik, D. Exploring the Prospective of Curcumin-loaded Nanomedicine in Brain Cancer Therapy: An Overview of Recent Updates and Patented Nanoformulations. Recent patents on nanotechnology 2024, 18, 278–294. doi:10.2174/1872210517666230823155328
  • Ghosh, B.; Datta, A.; Sarmah, D.; Rana, N.; Chaudhary, A.; Borah, A.; Bhattacharya, P. Nanomaterial-based approach in stroke. Natural Molecules in Neuroprotection and Neurotoxicity; Elsevier, 2024; pp 1935–1958. doi:10.1016/b978-0-443-23763-8.00082-8
  • Grosso, C.; Silva, A.; Delerue-Matos, C.; Barroso, M. F. Single and Multitarget Systems for Drug Delivery and Detection: Up-to-Date Strategies for Brain Disorders. Pharmaceuticals (Basel, Switzerland) 2023, 16, 1721. doi:10.3390/ph16121721
Other Beilstein-Institut Open Science Activities