Key for crossing the BBB with nanoparticles: the rational design

Scholarly Works

• Sierri, G.; Patrucco, M.; Ferrario, D.; Renda, A.; Comi, S.; Ciprandi, M.; Fontanini, V.; Sica, F. S.; Sesana, S.; Costa Verdugo, M.; Kravicz, M.; Salassa, L.; Busnelli, M.; Re, F. Targeting specific brain districts for advanced nanotherapies: A review from the perspective of precision nanomedicine. WIREs Nanomedicine and Nanobiotechnology 2024, 16. doi:10.1002/wnan.1991
• Preethi, M.; Adhav, S.; Kursunge, H.; Borse, V. Introduction to Nanoparticles as a Potential Carrier for Brain Targeting. Application of Nanocarriers in Brain Delivery of Therapeutics; Springer Nature Singapore, 2024; pp 43–68. doi:10.1007/978-981-97-2859-6_3
• Thakur, A. S.; Vishwas, S.; Badwaik, H.; Paul, S. D.; Sakure, K.; Nakhate, K. T. Liposomes as a Potential Carrier for Brain Delivery. Application of Nanocarriers in Brain Delivery of Therapeutics; Springer Nature Singapore, 2024; pp 141–185. doi:10.1007/978-981-97-2859-6_6
• Krsek, A.; Jagodic, A.; Baticic, L. Nanomedicine in Neuroprotection, Neuroregeneration, and Blood–Brain Barrier Modulation: A Narrative Review. Medicina 2024, 60, 1384. doi:10.3390/medicina60091384
• Fong, H.; Leid, Z. H.; Debnath, A. Approaches for Targeting Naegleria fowleri Using Nanoparticles and Artificial Peptides. Pathogens (Basel, Switzerland) 2024, 13, 695. doi:10.3390/pathogens13080695
• Gawel, A. M.; Betkowska, A.; Gajda, E.; Godlewska, M.; Gawel, D. Current Non-Metal Nanoparticle-Based Therapeutic Approaches for Glioblastoma Treatment. Biomedicines 2024, 12, 1822. doi:10.3390/biomedicines12081822
• Rivera López, E.; Samaniego López, C.; Spagnuolo, C. C.; Berardino, B. G.; Alaimo, A.; Pérez, O. E. Chitosan-Tricarbocyanine-Based Nanogels Were Able to Cross the Blood-Brain Barrier Showing Its Potential as a Targeted Site Delivery Agent. Pharmaceutics 2024, 16, 964. doi:10.3390/pharmaceutics16070964
• Kumar, P. T.; Budha, R. R.; Kumar, G. R.; Nagamani, B.; Rao, G. K. doi:10.1002/9781394159338.ch4
• Lei, J.; Huang, Y.; Zhao, Y.; Zhou, Z.; Mao, L.; Liu, Y. Nanotechnology as a new strategy for the diagnosis and treatment of gliomas. Journal of Cancer 2024, 15, 4643–4655. doi:10.7150/jca.96859
• Silant'ev, V. E.; Belousov, A. S.; Trukhin, F. O.; Struppul, N. E.; Shmelev, M. E.; Patlay, A. A.; Shatilov, R. A.; Kumeiko, V. V. Rational Design of Pectin-Chitosan Polyelectrolyte Nanoparticles for Enhanced Temozolomide Delivery in Brain Tumor Therapy. Biomedicines 2024, 12, 1393. doi:10.3390/biomedicines12071393
• Naik, B.; Sasikumar, J.; Das, S. P. From Skin and Gut to the Brain: The Infectious Journey of the Human Commensal Fungus Malassezia and Its Neurological Consequences. Molecular neurobiology 2024. doi:10.1007/s12035-024-04270-w
• Sadique, F. L.; Subramaiam, H.; Krishnappa, P.; Chellappan, D. K.; Ma, J. H. Recent advances in breast cancer metastasis with special emphasis on metastasis to the brain. Pathology, research and practice 2024, 260, 155378. doi:10.1016/j.prp.2024.155378
• Muolokwu, C. E.; Chaulagain, B.; Gothwal, A.; Mahanta, A. K.; Tagoe, B.; Lamsal, B.; Singh, J. Functionalized nanoparticles to deliver nucleic acids to the brain for the treatment of Alzheimer's disease. Frontiers in pharmacology 2024, 15, 1405423. doi:10.3389/fphar.2024.1405423
• Galindo, A. N.; Frey Rubio, D. A.; Hettiaratchi, M. H. Biomaterial strategies for regulating the neuroinflammatory response. Materials advances 2024, 5, 4025–4054. doi:10.1039/d3ma00736g
• Saleh, S. R.; Abd-Elmegied, A.; Aly Madhy, S.; Khattab, S. N.; Sheta, E.; Elnozahy, F. Y.; Mehanna, R. A.; Ghareeb, D. A.; Abd-Elmonem, N. M. Brain-targeted Tet-1 peptide-PLGA nanoparticles for berberine delivery against STZ-induced Alzheimer's disease in a rat model: Alleviation of hippocampal synaptic dysfunction, Tau pathology, and amyloidogenesis. International journal of pharmaceutics 2024, 658, 124218. doi:10.1016/j.ijpharm.2024.124218
• Cogill, S. A.; Lee, J.-H.; Jeon, M.-T.; Kim, D.-G.; Chang, Y. Hopping the Hurdle: Strategies to Enhance the Molecular Delivery to the Brain through the Blood-Brain Barrier. Cells 2024, 13, 789. doi:10.3390/cells13100789
• Forgham, H.; Zhu, J.; Huang, X.; Zhang, C.; Biggs, H.; Liu, L.; Wang, Y. C.; Fletcher, N.; Humphries, J.; Cowin, G.; Mardon, K.; Kavallaris, M.; Thurecht, K.; Davis, T. P.; Qiao, R. Multifunctional Fluoropolymer-Engineered Magnetic Nanoparticles to Facilitate Blood-Brain Barrier Penetration and Effective Gene Silencing in Medulloblastoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024, 11, e2401340. doi:10.1002/advs.202401340
• He, W.; Wang, N.; Wang, Y.; Liu, M.; Qing, Q.; Su, Q.; Zou, Y.; Liu, Y. Engineering Nanomedicine for Non-Viral RNA-Based Gene Therapy of Glioblastoma. Pharmaceutics 2024, 16, 482. doi:10.3390/pharmaceutics16040482
• Li, Z.; Kovshova, T.; Malinovskaya, J.; Knoll, J.; Shanehsazzadeh, S.; Osipova, N.; Chernysheva, A.; Melnikov, P.; Gelperina, S.; Wacker, M. G. Blood-Nanoparticle Interactions Create a Brain Delivery Superhighway for Doxorubicin. International journal of nanomedicine 2024, 19, 2039–2056. doi:10.2147/ijn.s440598
• Cai, J.-y.; Liu, Y.; Zhang, L.; Guo, R.-b.; Liu, Y.; Li, X.-t.; Ma, L.-y.; Kong, L. Menthol-modified paclitaxel multifunctional cationic liposomes cross the blood-brain barrier and target glioma stem cells for treatment of glioblastoma. Journal of Drug Delivery Science and Technology 2024, 93, 105387. doi:10.1016/j.jddst.2024.105387

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