Frontiers in pharmaceutical nanotechnology

  1. editorImage
  1. Editor: Prof. Dr. Matthias G. Wacker
    Department of Pharmacy
    Faculty of Science
    National University of Singapore

Today, a wide spectrum of nanomedicines is being developed for the diagnosis, prevention and treatment of disease. Recent breakthroughs include the delivery of small molecules, therapeutic proteins or peptides, and great progress has been made in the material design and targeting of nanocarriers to specific tissues or across biological barriers. However, converting the strategies into products is still challenging, and many nanomedicines fail to comply with the market requirements or during the clinical trials.

This thematic issue presents recent research in the design, manufacture and testing of nanomedicines, including contributions covering the following topics:

  • Development of drug delivery systems for pharmaceuticals and biopharmaceuticals (small molecules, proteins, nucleic acids)
  • Manufacturing and biomedical aspects of drug product design
  • Strategies and formulations for controlled drug transport across biological barriers
  • Physicochemical aspects of drug product development
  • Novel excipients for drug product design
  • Drug delivery and controlled release systems for systemic and local applications
  • Nanomaterials for therapeutic and diagnostic purposes

This thematic issue is dedicated to Prof. Dr. Jörg Kreuter, a pioneer of this whole research area, whose contributions have been widely recognized. With more than 300 publications, he has shaped pharmaceutical nanotechnology for the last 40 years.

Download all of the current publications in this thematic issue by clicking on "Issue PDF".

  • Editorial
  • Published 17 Dec 2019

Beilstein J. Nanotechnol. 2019, 10, 2538–2540, doi:10.3762/bjnano.10.244

Tungsten disulfide-based nanocomposites for photothermal therapy

  1. Tzuriel Levin,
  2. Hagit Sade,
  3. Rina Ben-Shabbat Binyamini,
  4. Maayan Pour,
  5. Iftach Nachman and
  6. Jean-Paul Lellouche
  • Full Research Paper
  • Published 02 Apr 2019

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  • Supp. Info

Beilstein J. Nanotechnol. 2019, 10, 811–822, doi:10.3762/bjnano.10.81

Serum type and concentration both affect the protein-corona composition of PLGA nanoparticles

  1. Katrin Partikel,
  2. Robin Korte,
  3. Dennis Mulac,
  4. Hans-Ulrich Humpf and
  5. Klaus Langer
  • Full Research Paper
  • Published 06 May 2019

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  • Supp. Info

Beilstein J. Nanotechnol. 2019, 10, 1002–1015, doi:10.3762/bjnano.10.101

  • Full Research Paper
  • Published 08 Aug 2019

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Beilstein J. Nanotechnol. 2019, 10, 1666–1678, doi:10.3762/bjnano.10.162

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

  1. Hannah Onafuye,
  2. Sebastian Pieper,
  3. Dennis Mulac,
  4. Jindrich Cinatl Jr.,
  5. Mark N. Wass,
  6. Klaus Langer and
  7. Martin Michaelis
  • Full Research Paper
  • Published 14 Aug 2019

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  • Supp. Info

Beilstein J. Nanotechnol. 2019, 10, 1707–1715, doi:10.3762/bjnano.10.166

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

  1. Elisabetta Esposito,
  2. Maddalena Sguizzato,
  3. Markus Drechsler,
  4. Paolo Mariani,
  5. Federica Carducci,
  6. Claudio Nastruzzi,
  7. Giuseppe Valacchi and
  8. Rita Cortesi
  • Full Research Paper
  • Published 29 Aug 2019

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Beilstein J. Nanotechnol. 2019, 10, 1789–1801, doi:10.3762/bjnano.10.174

  • Full Research Paper
  • Published 19 Sep 2019

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Beilstein J. Nanotechnol. 2019, 10, 1902–1913, doi:10.3762/bjnano.10.185

Incorporation of doxorubicin in different polymer nanoparticles and their anticancer activity

  1. Sebastian Pieper,
  2. Hannah Onafuye,
  3. Dennis Mulac,
  4. Jindrich Cinatl Jr.,
  5. Mark N. Wass,
  6. Martin Michaelis and
  7. Klaus Langer
  • Full Research Paper
  • Published 29 Oct 2019

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Beilstein J. Nanotechnol. 2019, 10, 2062–2072, doi:10.3762/bjnano.10.201

  • Review
  • Published 04 Nov 2019

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Beilstein J. Nanotechnol. 2019, 10, 2152–2162, doi:10.3762/bjnano.10.208

Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration

  1. Nashrawan Lababidi,
  2. Valentin Sigal,
  3. Aljoscha Koenneke,
  4. Konrad Schwarzkopf,
  5. Andreas Manz and
  6. Marc Schneider
  • Full Research Paper
  • Published 19 Nov 2019

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Beilstein J. Nanotechnol. 2019, 10, 2280–2293, doi:10.3762/bjnano.10.220

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

  1. Sabrina Barbosa de Souza Ferreira,
  2. Gustavo Braga,
  3. Évelin Lemos Oliveira,
  4. Jéssica Bassi da Silva,
  5. Hélen Cássia Rosseto,
  6. Lidiane Vizioli de Castro Hoshino,
  7. Mauro Luciano Baesso,
  8. Wilker Caetano,
  9. Craig Murdoch,
  10. Helen Elizabeth Colley and
  11. Marcos Luciano Bruschi
  • Full Research Paper
  • Published 25 Nov 2019

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  • Supp. Info

Beilstein J. Nanotechnol. 2019, 10, 2304–2328, doi:10.3762/bjnano.10.222

  • Review
  • Published 09 Jan 2020

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Beilstein J. Nanotechnol. 2020, 11, 101–123, doi:10.3762/bjnano.11.10

  • Full Research Paper
  • Published 17 Jan 2020

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  • Supp. Info

Beilstein J. Nanotechnol. 2020, 11, 213–224, doi:10.3762/bjnano.11.16

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