Coating with luminal gut-constituents alters adherence of nanoparticles to intestinal epithelial cells

Scholarly Works

• Le, H. T.; Lubian, A. F.; Bowring, B.; van der Poorten, D.; Iredell, J.; George, J.; Venturini, C.; Ahlenstiel, G.; Read, S. Using a human colonoid-derived monolayer to study bacteriophage translocation. Gut microbes 2024, 16, 2331520. doi:10.1080/19490976.2024.2331520
• Przybylla, R.; Krohn, M.; Sellin, M.-L.; Frank, M.; Oswald, S.; Linnebacher, M. Novel In Vitro Models for Cell Differentiation and Drug Transport Studies of the Human Intestine. Cells 2023, 12, 2371. doi:10.3390/cells12192371
• Mısırlı, N. S.; Pimtong, W.; Sillapaprayoon, S.; Chantho, V.; Saenmuangchin, R.; Aueviriyavit, S.; Dudak, F. C. Impact of a real food matrix and in vitro digestion on properties and acute toxicity of polystyrene microparticles. NanoImpact 2023, 32, 100482. doi:10.1016/j.impact.2023.100482
• Abou-Taleb, B. A.; Elzoheiry, I. F.; Kotry, G. S.; Khalafallah, N.; Kandil, S. H. Development of denture-fitting, palate-mucoadhesive miconazole nitrate films for denture stomatitis. Journal of Drug Delivery Science and Technology 2023, 81, 104263. doi:10.1016/j.jddst.2023.104263
• Rodrigues, A. C. B.; de Jesus, G. P.; Waked, D.; Gomes, G. L.; Silva, T. M.; Yariwake, V. Y.; da Silva, M. P.; Magaldi, A. J.; Veras, M. M. Scientific Evidence about the Risks of Micro and Nanoplastics (MNPLs) to Human Health and Their Exposure Routes through the Environment. Toxics 2022, 10, 308. doi:10.3390/toxics10060308
• Ali, S. S.; Al-Tohamy, R.; Koutra, E.; Moawad, M.; Kornaros, M.; Mustafa, A. M.; Mahmoud, Y. A.-G.; Badr, A.; Osman, M. E.; Elsamahy, T.; Jiao, H.; Sun, J. Nanobiotechnological advancements in agriculture and food industry: Applications, nanotoxicity, and future perspectives. The Science of the total environment 2021, 792, 148359. doi:10.1016/j.scitotenv.2021.148359
• Jia, Z.; Wignall, A.; Delon, L. C.; Guo, Z.; Prestidge, C. A.; Thierry, B. An ex Vivo Model Enables Systematic Investigation of the Intestinal Absorption and Transcytosis of Oral Particulate Nanocarriers. ACS biomaterials science & engineering 2021, 9, 2857–2867. doi:10.1021/acsbiomaterials.0c01355
• Zhang, Y.; Duan, S.; Liu, Y.; Wang, Y. The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs. Particle and fibre toxicology 2021, 18, 1–18. doi:10.1186/s12989-021-00399-x
• Guo, S.; Liang, Y.; Liu, L.; Yin, M.; Wang, A.; Sun, K.; Li, Y.; Shi, Y. Research on the fate of polymeric nanoparticles in the process of the intestinal absorption based on model nanoparticles with various characteristics: size, surface charge and pro-hydrophobics. Journal of nanobiotechnology 2021, 19, 32. doi:10.1186/s12951-021-00770-2
• Jia, Z.; Wignall, A.; Prestidge, C. A.; Thierry, B. An ex vivo investigation of the intestinal uptake and translocation of nanoparticles targeted to Peyer's patches microfold cells. International journal of pharmaceutics 2020, 594, 120167. doi:10.1016/j.ijpharm.2020.120167
• Paul, M. B.; Stock, V.; Cara-Carmona, J.; Lisicki, E.; Shopova, S.; Fessard, V.; Braeuning, A.; Sieg, H.; Böhmert, L. Micro- and nanoplastics – current state of knowledge with the focus on oral uptake and toxicity. Nanoscale advances 2020, 2, 4350–4367. doi:10.1039/d0na00539h
• Liang, D.; Wang, X.; Wang, Y.; Dong, Z.; Zhao, X.; Fan, W. The dual effect of natural organic matter on the two-step internalization process of Au@Sio2 in freshwater. Water research 2020, 184, 116216. doi:10.1016/j.watres.2020.116216
• Muraleetharan, V.; Mantaj, J.; Swedrowska, M.; Vllasaliu, D. Nanoparticle modification in biological media: implications for oral nanomedicines. RSC advances 2019, 9, 40487–40497. doi:10.1039/c9ra08403g
• Frey, A.; Ramaker, K.; Röckendorf, N.; Wollenberg, B.; Lautenschläger, I.; Gébel, G.; Giemsa, A.; Heine, M.; Bargheer, D.; Nielsen, P. Fate and Translocation of (Nano)Particulate Matter in the Gastrointestinal Tract. Biological Responses to Nanoscale Particles; Springer International Publishing, 2019; pp 281–327. doi:10.1007/978-3-030-12461-8_12
• Vllasaliu, D.; Thanou, M.; Stolnik, S.; Fowler, R. Recent advances in oral delivery of biologics: nanomedicine and physical modes of delivery. Expert opinion on drug delivery 2018, 15, 759–770. doi:10.1080/17425247.2018.1504017
• Azcona, P.; López-Corral, I.; Lassalle, V. L. Fabrication of folic acid magnetic nanotheranostics: An insight on the formation mechanism, physicochemical properties and stability in simulated physiological media. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2018, 537, 185–196. doi:10.1016/j.colsurfa.2017.10.025
• Ye, D.; Bramini, M.; Hristov, D. R.; Wan, S.; Salvati, A.; Åberg, C.; Dawson, K. A. Low uptake of silica nanoparticles in Caco-2 intestinal epithelial barriers. Beilstein journal of nanotechnology 2017, 8, 1396–1406. doi:10.3762/bjnano.8.141
• de Jong, W. H.; Oomen, A.; Tran, L.; Chaudhry, Q.; Lefebvre, D. E. CHAPTER 10:Engineered Nanoparticles and Food: Exposure, Toxicokinetics, Hazards and Risks. Nanotechnologies in Food; The Royal Society of Chemistry, 2017; pp 200–227. doi:10.1039/9781782626879-00200
• Zu, Y.; Yong, Y.; Zhang, X.; Yu, J.; Dong, X.; Yin, W.; Yan, L.; Zhao, F.; Gu, Z.; Zhao, Y. Protein-directed synthesis of Bi2S3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract. RSC Advances 2017, 7, 17505–17513. doi:10.1039/c7ra01526g
• Heringa, M. B.; Geraets, L.; van Eijkeren, J. C. H.; Vandebriel, R. J.; de Jong, W. H.; Oomen, A. G. Risk assessment of titanium dioxide nanoparticles via oral exposure, including toxicokinetic considerations. Nanotoxicology 2016, 10, 1515–1525. doi:10.1080/17435390.2016.1238113

Explore citations to this article at