Proinflammatory and cytotoxic response to nanoparticles in precision-cut lung slices

Scholarly Works

• Furer, L. A.; Abad, Á. D.; Manser, P.; Hannig, Y.; Schuerle, S.; Fortunato, G.; Buerki-Thurnherr, T. Novel electrospun chitosan/PEO membranes for more predictive nanoparticle transport studies at biological barriers. Nanoscale 2022, 14, 12136–12152. doi:10.1039/d2nr01742c
• Michalaki, C.; Dean, C.; Johansson, C. The Use of Precision-Cut Lung Slices for Studying Innate Immunity to Viral Infections. Current protocols 2022, 2, e505. doi:10.1002/cpz1.505
• González-Vega, J. G.; García-Ramos, J. C.; Chavez-Santoscoy, R. A.; Castillo-Quiñones, J. E.; Arellano-Garcia, M. E.; Toledano-Magaña, Y. Lung Models to Evaluate Silver Nanoparticles' Toxicity and Their Impact on Human Health. Nanomaterials (Basel, Switzerland) 2022, 12, 2316. doi:10.3390/nano12132316
• Viney, C.; Tatler, A. L. In Vitro Models to Study Respiratory Biology and Diseases. Encyclopedia of Respiratory Medicine; Elsevier, 2022; pp 773–778. doi:10.1016/b978-0-08-102723-3.00072-x
• Tigges, J.; Eggerbauer, F.; Worek, F.; Thiermann, H.; Rauen, U.; Wille, T. Optimization of long-term cold storage of rat precision-cut lung slices with a tissue preservation solution. American journal of physiology. Lung cellular and molecular physiology 2021, 321, L1023–L1035. doi:10.1152/ajplung.00076.2021
• Selo, M. A.; Sake, J. A.; Kim, K.-J.; Ehrhardt, C. In vitro and ex vivo models in inhalation biopharmaceutical research - advances, challenges and future perspectives. Advanced drug delivery reviews 2021, 177, 113862. doi:10.1016/j.addr.2021.113862
• Kreutzer, F. P.; Meinecke, A.; Schmidt, K.; Fiedler, J.; Thum, T. Alternative strategies in cardiac preclinical research and new clinical trial formats. Cardiovascular research 2021, 118, 746–762. doi:10.1093/cvr/cvab075
• Löfdahl, A.; Jern, A.; Flyman, S.; Kåredal, M.; Karlsson, H. L.; Larsson-Callerfelt, A.-K. Silver Nanoparticles Alter Cell Viability Ex Vivo and in Vitro and Induce Proinflammatory Effects in Human Lung Fibroblasts. Nanomaterials (Basel, Switzerland) 2020, 10, 1868. doi:10.3390/nano10091868
• Liggitt, H. D. Evaluation of Biodistribution, Toxicology, and Toxicologic Pathology of Nanomaterials Used to Deliver Nucleic Acids. Nanotechnology Characterization Tools for Environment, Health, and Safety; Springer Berlin Heidelberg, 2019; pp 65–102. doi:10.1007/978-3-662-59600-5_3
• Kersting, D.; Fasbender, S.; Pilch, R.; Kurth, J.; Franken, A.; Ludescher, M.; Naskou, J.; Hallenberger, A.; von Gall, C.; Mohr, C. J.; Lukowski, R.; Raba, K.; Jaschinski, S.; Esposito, I.; Fischer, J. C.; Fehm, T.; Niederacher, D.; Neubauer, H.; Heinzel, T. From in vitro to ex vivo: subcellular localization and uptake of graphene quantum dots into solid tumors. Nanotechnology 2019, 30, 395101. doi:10.1088/1361-6528/ab2cb4
• Chernozem, R. V.; Surmeneva, M. A.; Krause, B.; Baumbach, T.; Ignatov, V. P.; Prymak, O.; Loza, K.; Epple, M.; Ennen-Roth, F.; Wittmar, A.; Ulbricht, M.; Chudinova, E.; Rijavec, T.; Lapanje, A.; Surmenev, R. A. Functionalization of titania nanotubes with electrophoretically deposited silver and calcium phosphate nanoparticles: Structure, composition and antibacterial assay. Materials science & engineering. C, Materials for biological applications 2018, 97, 420–430. doi:10.1016/j.msec.2018.12.045
• Guggenheim, E. J.; Milani, S.; Röttgermann, P. J. F.; Dusinska, M.; Saout, C.; Salvati, A.; Rädler, J. O.; Lynch, I. Refining in vitro models for nanomaterial exposure to cells and tissues. NanoImpact 2018, 10, 121–142. doi:10.1016/j.impact.2018.02.008
• Bierkandt, F. S.; Leibrock, L.; Wagener, S.; Laux, P.; Luch, A. The impact of nanomaterial characteristics on inhalation toxicity. Toxicology research 2018, 7, 321–346. doi:10.1039/c7tx00242d
• Herbert, J.; Thiermann, H.; Worek, F.; Wille, T. Precision cut lung slices as test system for candidate therapeutics in organophosphate poisoning. Toxicology 2017, 389, 94–100. doi:10.1016/j.tox.2017.07.011
• Shatkin, J. A.; Ong, K. J. Alternative Testing Strategies for Nanomaterials: State of the Science and Considerations for Risk Analysis. Risk analysis : an official publication of the Society for Risk Analysis 2016, 36, 1564–1580. doi:10.1111/risa.12642
• Kermanizadeh, A.; Gosens, I.; MacCalman, L.; Johnston, H. J.; Danielsen, P. H.; Jacobsen, N. R.; Lenz, A.-G.; Fernandes, T. F.; Schins, R. P. F.; Cassee, F. R.; Wallin, H.; Kreyling, W. G.; Stoeger, T.; Loft, S.; Møller, P.; Tran, C. L.; Stone, V. A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges. Journal of toxicology and environmental health. Part B, Critical reviews 2016, 19, 1–28. doi:10.1080/10937404.2015.1126210
• Ahlberg, S.; Antonopulos, A.; Diendorf, J.; Dringen, R.; Epple, M.; Flöck, R.; Goedecke, W.; Graf, C.; Haberl, N.; Helmlinger, J.; Herzog, F.; Heuer, F.; Hirn, S.; Johannes, C.; Kittler, S.; Köller, M.; Korn, K.; Kreyling, W. G.; Krombach, F.; Lademann, J.; Loza, K.; Luther, E. M.; Malissek, M.; Meinke, M. C.; Nordmeyer, D.; Pailliart, A.; Raabe, J.; Rancan, F.; Rothen-Rutishauser, B.; Rühl, E.; Schleh, C.; Seibel, A.; Sengstock, C.; Treuel, L.; Vogt, A.; Weber, K.; Zellner, R. PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments. Beilstein journal of nanotechnology 2014, 5, 1944–1965. doi:10.3762/bjnano.5.205

Explore citations to this article at