6 article(s) from Rothen-Rutishauser, Barbara
- Full Research Paper
- Published 14 Nov 2017
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Figure 1: Characterization of the NPs used and their calculated deposition on the cellular monolayer. Transmi...
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Figure 2: Environmental scanning electron microscopy of J774A.1 macrophages 5 min after NP exposure. Both spe...
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Figure 3: Live cell imaging via laser scanning microscopy over 50 min after the onset of NP exposure. AuNPs a...
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Figure 4: The intracellular localisation of the NPs 24 h after exposure. (a) Overview showing a part of a cel...
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Figure 5: Quantification of uptake by ICP-OES and LSM combined with digital analysis. ICP-OES measurements re...
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Figure 6: Mean fluorescence intensity of the intracellular pixels over time. The intensity of the pixels asso...
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Figure 7: Time-dependent colocalisation of AuNPs and FeOxNPs with lysosomal markers. The Pearson’s colocalisa...
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Figure 8: Colocalisation of AuNPs and FeOxNPs with the lysosomal marker. The interplay of AuNPs, FeOxNPs and ...
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Figure 9: Effect of MDC treatment on the uptake of AuNPs and FeOxNPs. The uptake is partially blocked in the ...
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- Full Research Paper
- Published 18 Dec 2014
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Figure 1: Cell viability as measured by LDH release in PCLS culture medium at 0, 4, 24, 48, and 72 h after pr...
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Figure 2: Viability of PCLS as determined by WST-1 conversion at 0, 4, 24, 48, and 72 h after preparation of ...
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Figure 3: Cell proliferation in PCLS as determined by Click-iT® EdU Alexa Fluor® 488 Imaging Kit (Invitrogen)...
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Figure 4: Cytotoxic response of PCLS as measured by LDH release after 4 and 24 h incubation. Results were cal...
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Figure 5: Cytotoxic response of PCLS as measured by WST-1 conversion after 4 and 24 h incubation (n = 5; #p <...
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Figure 6: A: CXCL-1 levels measured in the PCLS culture medium after 4 and 24 h of incubation; B: TNF-α-level...
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Figure 7: Multiphoton microscopy of Ag-NPs in the lung tissue. Image of an 80 µm median cryosection of PCLS i...
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- Review
- Published 03 Nov 2014
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Figure 1: SEM images of silver nanocubes (A) and a mixture of silver nanoparticles with different shapes and ...
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Figure 2: Representative scanning electron microscopy image of PVP-coated silver nanoparticles (A) and partic...
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Figure 3: Dissolution of silver nanoparticles immersed in pure water, argon-saturated water under argon atmos...
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Figure 4: (A) CD spectra of pure dissolved bovine serum albumin (thick black line) and in the presence of dif...
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Figure 5: A: STXM images at 510 eV of human mesenchymal stem cells (hMSC) after 24 h of incubation with spher...
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Figure 6: Agglomeration of internalized silver nanoparticles in hMSC analyzed by phase contrast microscopy (B...
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Figure 7: Intracellular occurrence of agglomerated silver nanoparticles in PBMC analyzed through microscopy. ...
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Figure 8: Proof of intracellular localization of silver nanoparticle agglomerates in monocytes and lymphocyte...
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Figure 9: Localization of silver nanoparticles agglomerates in hMSC. A representative light micrograph after ...
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Figure 10: Decrease in the amount of silver agglomerates within hMSC after prolonged cell culture. hMSC were p...
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Figure 11: Uptake and metabolism of silver nanoparticles in brain astrocytes. Data from cultured astrocytes su...
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Figure 12: Damaged cells given in percent by scoring for CA in CHO9 (n = 816, p > 0.999), K1 (n = 1851, p > 0....
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Figure 13: The diagram shows the distribution of sister-chromatid exchanges (SCE) in untreated cells (black ba...
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Figure 14: These diagrams summarize the quantification of foci formation in CHO9, K1 and V79B. Data derived fr...
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Figure 15: The diagram shows the distribution of twin SCE (black bars) and single SCE (grey bars) in CHO K1 ce...
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Figure 16: Schematic image of the triple-cell co-culture model consisting of MDMs (blue), A549 cells (red), a ...
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Figure 17: Cytotoxic effects and free radical production by silver nanoparticles per se versus the effects due...
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- Full Research Paper
- Published 24 Sep 2014
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Figure 1: Characterization of polystyrene particles. (A) Characteristics of the particles as measured by dyna...
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Figure 2: LSM images demonstrate the presence of the different endocytotic uptake proteins within J774A.1 mac...
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Figure 3: Investigation of cell morphology after inhibitor treatment. Healthy cells (green inset) retained th...
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Figure 4: Fluorescence intensity profiles of J774A.1 cells, 40 nm PS NPs with clathrin heavy chain or flotill...
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Figure 5: Laser scanning microscopy imaging revealed particle uptake in J774A.1 and A549 cells. (A–C) Uptake ...
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In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?
- Review
- Published 09 Sep 2014
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Figure 1: An overview of the “zoo” of different NPs concerning their composition, functionality, and fields o...
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Figure 2: Hybrid nature of typical NPs, comprising different structural compartments. Reproduced with permiss...
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Figure 3: Scheme depicting the different mechanisms of cellular endocytosis. Reproduced with permission from [41]...
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Figure 4: Fluorescence microscopy image showing the granular structure of internalized NPs inside A549 lung c...
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Figure 5: a) A microparticle has been internalized by an A549 lung cancer cell into an intracellular vesicle ...
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Figure 6: Intracellular compartments after internalization of PEG-coated gold NPs as visualized with TEM. The...
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Figure 7: TEM images of a) dispersed and b) agglomerated Au NPs. The scale bars correspond to 100 nm. Adopted...
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- Full Research Paper
- Published 26 Aug 2014
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Figure 1: Scanning electron microscopic image (A) of Ag NPs deposited on a silicon wafer. The particle size d...
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Figure 2: Illustrated are triple cell co-cultures at the air–liquid interface and under submerged conditions,...
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Figure 3: Ag NP aggregates were found in the upper cell layer of the transwell membrane. A representative ima...
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Figure 4: Extracellular LDH release was quantified relative to the untreated control (reference: red dashed l...
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Figure 5: The extracellular release of pro-inflammatory markers was analysed by ELISA. Excreted TNF-α (A and ...
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Figure 6: 4 and 24 h after cell exposure, the total RNA content was collected. Subsequent analysis by real-ti...
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