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Search for "surface charge" in Full Text gives 204 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Interaction of graphene oxide with tannic acid: computational modeling and toxicity mitigation in C. elegans

  • Romana Petry,
  • James M. de Almeida,
  • Francine Côa,
  • Felipe Crasto de Lima,
  • Diego Stéfani T. Martinez and
  • Adalberto Fazzio

Beilstein J. Nanotechnol. 2024, 15, 1297–1311, doi:10.3762/bjnano.15.105

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  • and biological/environmental application. The properties of the materials in biological environments may differ significantly depending on the composition of the medium (e.g., aggregation state, surface charge, and dissolution) and determine their biological effects. Therefore, the initial step to
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Published 30 Oct 2024

Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids

  • Iris Renata Sousa Ribeiro,
  • Raquel Frenedoso da Silva,
  • Romênia Ramos Domingues,
  • Adriana Franco Paes Leme and
  • Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

Graphical Abstract
  • groups would not be available to contribute to the surface charge and the ZW structure has a net neutral charge, which does not interfere with the NP charge. The maintenance of the negative charge can be explained by the existence of remaining silanol groups on the surface of SiO2NPs, resulting from a
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Published 07 Oct 2024

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers

  • Ömür Acet,
  • Pavel Kirsanov,
  • Burcu Önal Acet,
  • Inessa Halets-Bui,
  • Dzmitry Shcharbin,
  • Şeyda Ceylan Cömert and
  • Mehmet Odabaşı

Beilstein J. Nanotechnol. 2024, 15, 1189–1196, doi:10.3762/bjnano.15.96

Graphical Abstract
  • . Physicochemical features such as size, shape, and surface charge play an extremely important role in the internalization of nanostructures. The uptake of nanoparticles into cells requires two steps. The first is the binding to the cell membrane, and the second is the uptake into the cell [34]. The zeta potential
  • of SNPs was measured as +14.1 mV at pH 7.0 [24]. Nanostructures with this surface charge will repel each other and will not aggregate. The high surface charge of the SNPs can be seen as evidence of suspension stability. In addition, the positively charged nanostructures are preferentially bound to
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Published 26 Sep 2024

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

  • Damai Ria Setyawati,
  • Fransiska Christydira Sekaringtyas,
  • Riyona Desvy Pratiwi,
  • A’liyatur Rosyidah,
  • Rohimmahtunnissa Azhar,
  • Nunik Gustini,
  • Gita Syahputra,
  • Idah Rosidah,
  • Etik Mardliyati,
  • Tarwadi and
  • Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

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  • impermeable basal lamina allow for rapid accumulation of NPs in the liver through passive targeting [24]. Complementing certain anatomic or pathophysiological features of the target organ, such passive accumulation also relies on nanoparticle properties including size, shape, surface charge, and
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Published 23 Aug 2024

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

  • Shakhzodjon Uzokboev,
  • Khojimukhammad Akhmadbekov,
  • Ra’no Nuritdinova,
  • Salah M. Tawfik and
  • Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

Graphical Abstract
  • early diagnosis and improved treatment outcomes [98]. In environmental monitoring, alginate nanoparticles have been employed for the detection of pollutants and contaminants in water and air, helping to ensure environmental safety [99]. The main factor for the sensing ability of alginate is the surface
  • charge on the polymer. It is critical in enabling quick electron transfer between an enzyme and an electrode surface, triggering the enzyme’s catalytic function for rapid biosensing [100]. Environmental sensing applications One key advantage of using nanosensors in environmental sensing is their ability
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Published 22 Aug 2024

Entry of nanoparticles into cells and tissues: status and challenges

  • Kirsten Sandvig,
  • Tore Geir Iversen and
  • Tore Skotland

Beilstein J. Nanotechnol. 2024, 15, 1017–1029, doi:10.3762/bjnano.15.83

Graphical Abstract
  • of new types of NPs, there is a knowledge gap when it comes to our understanding of the interaction of NPs with both cells and tissues. However, it is well known that NP properties, such as surface charge, size, and the material they are composed of can affect cellular uptake, biodistribution, and
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Published 12 Aug 2024

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

  • Thi Ngoc Han Pham,
  • Phuong-Thao Dang-Luong,
  • Hong-Phuc Nguyen,
  • Loc Le-Tuan,
  • Xuan Thang Cao,
  • Thanh-Danh Nguyen,
  • Vy Tran Anh and
  • Hieu Vu_Quang

Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78

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  • nanoprecipitation technique, resulting in small size, high homogeneity, and negative surface charge. Importantly, the folate-targeted nanoparticles demonstrated enhanced uptake and cytotoxicity in folate receptor-positive cancer cell lines (MCF-7 and HepG-2) compared to folate receptor-negative cells (HEK 293
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Published 31 Jul 2024

Identification of structural features of surface modifiers in engineered nanostructured metal oxides regarding cell uptake through ML-based classification

  • Indrasis Dasgupta,
  • Totan Das,
  • Biplab Das and
  • Shovanlal Gayen

Beilstein J. Nanotechnol. 2024, 15, 909–924, doi:10.3762/bjnano.15.75

Graphical Abstract
  • , shape, and surface charge of NPs, as well as their surface functionalization. In the current study, classification-based ML models (i.e., Bayesian classification, random forest, support vector classifier, and linear discriminant analysis) have been developed to identify the features/fingerprints that
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Published 22 Jul 2024

A review on the structural characterization of nanomaterials for nano-QSAR models

  • Salvador Moncho,
  • Eva Serrano-Candelas,
  • Jesús Vicente de Julián-Ortiz and
  • Rafael Gozalbes

Beilstein J. Nanotechnol. 2024, 15, 854–866, doi:10.3762/bjnano.15.71

Graphical Abstract
  • group the data into categories [60]. Related measures are the isoelectric point, which corresponds to the pH at which a nanoparticle suspension has zero zeta potential [15][17], the surface charge [31][36][63], the conductivity [77], and the electrophoretic mobility [77]. Magnetic properties are also
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Published 11 Jul 2024

Exploring surface charge dynamics: implications for AFM height measurements in 2D materials

  • Mario Navarro-Rodriguez,
  • Andres M. Somoza and
  • Elisa Palacios-Lidon

Beilstein J. Nanotechnol. 2024, 15, 767–780, doi:10.3762/bjnano.15.64

Graphical Abstract
  • field. The electric field is induced by both the presence of the tip (at voltage Vbias) and by the surface charge density. The electric field must then verify Maxwell’s first equation, ∇·E = ρ/ε, above and below the surface, whose general solution is where Vtip(x, y, z , t) is the potential generated by
  • the tip in the absence of charges, the second term on the right-hand side is the potential generated by the charges at the surface, n(x, y, t) is the surface charge density, and V1(x′, y′, z′; x, y, z, t) is the potential at position (x, y, z) generated by a unit charge located at (x′, y′, z′). Vtip(x
  • analytically in Fourier space. A first consequence in this case is that, as t→∞, there will be a surface charge density that will depend on the bulk conductivities and the surface conductivity, This equation shows that, initially, the tip generates an electric field that gives rise to currents at the surface
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Published 01 Jul 2024

Laser synthesis of nanoparticles in organic solvents – products, reactions, and perspectives

  • Theo Fromme,
  • Sven Reichenberger,
  • Katharine M. Tibbetts and
  • Stephan Barcikowski

Beilstein J. Nanotechnol. 2024, 15, 638–663, doi:10.3762/bjnano.15.54

Graphical Abstract
  • the ionic strength of the added salts and the obtained gold particle size (Figure 2). The surface oxidation increased with the anion’s surface charge density until a plateau of around 60% was reached. A further increase in ionic strength showed no change in surface oxidation, which was attributed to
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Published 05 Jun 2024

On the additive artificial intelligence-based discovery of nanoparticle neurodegenerative disease drug delivery systems

  • Shan He,
  • Julen Segura Abarrategi,
  • Harbil Bediaga,
  • Sonia Arrasate and
  • Humberto González-Díaz

Beilstein J. Nanotechnol. 2024, 15, 535–555, doi:10.3762/bjnano.15.47

Graphical Abstract
  • majority of NPs for NDD delivery in this database is in the range of 70–115 nm. Recently, Chithrani et al. [91] have demonstrated that size, coating, and surface charge of nanoparticles have a crucial impact on the intracellular uptake process. Similarly, Shilo et al. have investigated the influence of NP
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Published 15 May 2024
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  • , nanoparticles can easily agglomerate into particles with larger diameter. Upon intake by organisms, depending on the pH value, these agglomerations disintegrate again becoming a source for toxins in the body [8]. The formation of agglomerated NPs depends upon the surface charge of the NPs, which is believed to
  • stabilize and prevent agglomeration of NPs. As no experimental techniques are available to measure the surface charge directly, its value is measured through the zeta potential (ζ) in a given medium [9]. Zeta potential is the electrostatic potential at the electrical double layer surrounding the NPs in
  • protein corona. The formation of a protein corona on the surface of NPs, which influences the interaction with cell membranes or proteins, is also associated with zeta potential and surface charge. Very limited studies have reported the influence of zeta potential, surface charge, hydrophobicity, and
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Published 12 Mar 2024

Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

  • Zeynep Özcan and
  • Afife Binnaz Hazar Yoruç

Beilstein J. Nanotechnol. 2024, 15, 256–269, doi:10.3762/bjnano.15.24

Graphical Abstract
  • modulate the chemical environment in which the polymerization occurs [57]. Consequently, pH alterations may induce changes in the surface charge of the nanoparticles. This could profoundly affect the drug binding capacity of the nanoparticles and implies that the nanoparticles may exhibit varying
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Published 28 Feb 2024

Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

  • Douglas Dourado,
  • Thayse Silva Medeiros,
  • Éverton do Nascimento Alencar,
  • Edijane Matos Sales and
  • Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

Graphical Abstract
  • delivery specific to macrophage targets, such as ᴅ-mannose, phosphatidylserine, or lactoferrin. This may reduce the drug resistance of the parasite in the long term. Furthermore, the surface charge of nanostructures may influence internalization since positive charges favor electrostatic interactions of
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Published 04 Jan 2024

Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

  • Agnes-Valencia Weiss and
  • Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

Graphical Abstract
  • examining the characteristics of nanoparticles used for drug delivery, one can see that some are better understood then others. The size of nanoparticles, for example, is shown to play an important role in tissue or mucus penetration [8] and in cellular uptake [9]. Also surface charge and chemical
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Published 23 Nov 2023

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

  • Nittiya Suwannasom,
  • Netsai Sriaksorn,
  • Chutamas Thepmalee,
  • Krissana Khoothiam,
  • Ausanai Prapan,
  • Hans Bäumler and
  • Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

Graphical Abstract
  • HSA-MPs reflects the negative charge of the albumin biopolymers [26]. In fact, in the cationic HSA-MPs with negative charges, CUR loading did not alter the zeta potential of CUR-HSA-MPs. Furthermore, particles with negative surface charge exhibit the enhanced permeability and retention (EPR) effect
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Published 21 Nov 2023

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

  • Mamta Kumari,
  • Amitabha Acharya and
  • Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

Graphical Abstract
  • surface charge [36][37]. Surface modification strategies include, for example, adsorption, covalent conjugation, and biotin–avidin interaction, which will be discussed below in detail with examples. Adsorption Adsorption of antibodies on the surface of NPs is a non-covalent reversible binding method
  • properties by reducing surface charge and availability of conjugated molecules on the NPs, which results in a reduction of targeting capacity from 70% to 7%. However, HAS-incubated NPs exhibited increased interaction between targeting molecule and ligand, boosting the targeting capacity of Afb-conjugated NPs
  • through the antibodies [94]. Additionally, these targeted NPs internalize the chemotherapeutics precisely into tumor cells with minimal drug leakage and also provide protection from degradation and elimination [95]. The controlled size and surface charge of NPs avoid the rapid renal clearance of the NPs
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Published 04 Sep 2023

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

  • Giuliana Muraca,
  • María Esperanza Ruiz,
  • Rocío C. Gambaro,
  • Sebastián Scioli-Montoto,
  • María Laura Sbaraglini,
  • Gisel Padula,
  • José Sebastián Cisneros,
  • Cecilia Yamil Chain,
  • Vera A. Álvarez,
  • Cristián Huck-Iriart,
  • Guillermo R. Castro,
  • María Belén Piñero,
  • Matias Ildebrando Marchetto,
  • Catalina Alba Soto,
  • Germán A. Islan and
  • Alan Talevi

Beilstein J. Nanotechnol. 2023, 14, 804–818, doi:10.3762/bjnano.14.66

Graphical Abstract
  • high-negative ζ values may impede cellular uptake [40]. On the other hand, it was observed that the nanoparticulated systems remained stable after six months with no precipitation. This suggests that in this case the stabilization is not achieved by means of surface charge alone, but also by the steric
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Published 28 Jul 2023

ZnO-decorated SiC@C hybrids with strong electromagnetic absorption

  • Liqun Duan,
  • Zhiqian Yang,
  • Yilu Xia,
  • Xiaoqing Dai,
  • Jian’an Wu and
  • Minqian Sun

Beilstein J. Nanotechnol. 2023, 14, 565–573, doi:10.3762/bjnano.14.47

Graphical Abstract
  • particles possibly results in surface charge redistribution and generates interfacial polarization effects (Figure 7c). Liao et al. [39] reported a kind of multiphase nanocomposite (Co/ZnO/C) with porous structure for EM absorption. The best RLmin value of this material was −52.6 dB at a thickness of 3 mm
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Published 04 May 2023

Polymer nanoparticles from low-energy nanoemulsions for biomedical applications

  • Santiago Grijalvo and
  • Carlos Rodriguez-Abreu

Beilstein J. Nanotechnol. 2023, 14, 339–350, doi:10.3762/bjnano.14.29

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  • surface charge (ca. −11 mV). The drug encapsulation efficiencies were higher than 98%, although loadings were not enough to achieve therapeutic concentrations. The GAL release from the nanoparticles was slower than that from aqueous GAL solutions and surfactant micelles. Viabilities of HeLa and SH-SY5Y
  • /(ricinoleamidopropyltrimonium methosulfate/Kolliphor® EL)/4% PLGA in ethyl acetate [61]. The nanoparticles displayed a hydrodynamic diameter of ca. 125 nm for an O/S ratio of 70/30, and the size increased with the O/S ratio. The surface charge can be tuned by changing the cationic/nonionic surfactant ratio, that is, the
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Published 13 Mar 2023

Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles

  • Magdalena Lasak and
  • Karol Ciepluch

Beilstein J. Nanotechnol. 2023, 14, 329–338, doi:10.3762/bjnano.14.28

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  • [18][19][20][21][22][23]. NPs exhibit unique physicochemical properties that enable them to overcome biological barriers, such as negative surface charge and sizes from 5 to 50 nm. Moreover, most of the administered NPs eventually end up in the bloodstream, which facilitates their interaction with the
  • effectiveness of NanoEL closely depends on the physicochemical properties of the NPs such as size, shape, density, and surface charge [12][19][20][21]. Moreover, it is worth to mention that the biological effects of NPs to endothelial cells also depend on the microenvironments. The adhesion of proteins and/or
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Published 08 Mar 2023

Bismuth-based nanostructured photocatalysts for the remediation of antibiotics and organic dyes

  • Akeem Adeyemi Oladipo and
  • Faisal Suleiman Mustafa

Beilstein J. Nanotechnol. 2023, 14, 291–321, doi:10.3762/bjnano.14.26

Graphical Abstract
  • surface charge, low carrier density, small electron effective mass, long electron mean free path, and extremely low band overlap energy, bismuth can transition from a semimetal to a semiconductor by shrinking its crystallite size [25][71][72][73][74][75][76][77]. To hasten the separation of photogenerated
  • function excellently at all pH values. For instance, electrostatic repulsion may reduce the effectiveness of the degradation process if the photocatalytic experiment is carried out at a pH value at which photocatalyst and pollutant species have the same surface charge. For instance, lower removal
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Published 03 Mar 2023

Biocatalytic synthesis and ordered self-assembly of silica nanoparticles via a silica-binding peptide

  • Mustafa Gungormus

Beilstein J. Nanotechnol. 2023, 14, 280–290, doi:10.3762/bjnano.14.25

Graphical Abstract
  • with NH3, the SiBP produces smaller and more uniformly distributed submicrometer particles. The SiBP also improves the long-range self-assembly of the as-grown particles into an opal-like structure by changing the surface charge, without any need for further modification or processing of the particles
  • the particles through a capping agent-like effect. (3) The SiBP can increase the efficiency of the self-assembly by modifying the net surface charge of the particle. To test these hypotheses, we have synthesized SiO2 particles with the Stöber method using the SiBP as the only catalyst or in
  • combination with NH3. The reaction kinetics were monitored via measuring the optical density (OD) with UV–vis spectroscopy and the conversion of substrate via gas chromatography coupled with mass spectroscopy (GC–MS). Size and net surface charge distribution of the particles were determined with dynamic light
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Published 28 Feb 2023

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

  • Filip Gorachinov,
  • Fatima Mraiche,
  • Diala Alhaj Moustafa,
  • Ola Hishari,
  • Yomna Ismail,
  • Jensa Joseph,
  • Maja Simonoska Crcarevska,
  • Marija Glavas Dodov,
  • Nikola Geskovski and
  • Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

Graphical Abstract
  • delivery to the liver are: (i) DLin-MC3-DMA (an ionizable cationic lipid that contains amine functions with an acid dissociation constant of ca. 6.5, neutral at physiological pH and relatively non-toxic and non-immunogenic because of a low surface charge in the physiological environment), (ii) distearoyl
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Published 22 Feb 2023
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