Parylene-coated platinum nanowire electrodes for biomolecular sensing applications

• Chao Liu,
• Peker Milas,
• Michael G. Spencer and
• Birol Ozturk

Beilstein J. Nanotechnol. 2025, 16, 1392–1400, doi:10.3762/bjnano.16.101

• . developed a glucose sensor using copper nanowires and CNTs, achieving a limit of detection as low as 0.3 nM, highlighting the remarkable sensitivity of CNT-based electrodes [9]. Nevertheless, several studies reported the toxicity of CNTs for tissues and cells including loss of cellular integrity, DNA damage

• advantage makes them suitable for biosensing applications with high spatial resolution involving single cells. The morphology and functionality of the electrodes were characterized through elemental analysis and copper deposition, demonstrating their capability for effective surface modification. Results

Synthesis and antibacterial properties of nanosilver-modified cellulose triacetate membranes for seawater desalination

• Lei Wang,
• Shizhe Li,
• Kexin Xu,
• Wenjun Li,
• Ying Li and
• Gang Liu

Beilstein J. Nanotechnol. 2025, 16, 1380–1391, doi:10.3762/bjnano.16.100

• ) membrane for water desalination. The TiO2-modified membrane demonstrated significant antibacterial activity against Escherichia coli. Under UV light, the survival ratio of bacterial cells reduced to 5% within 4 h; the membrane was completely sterilized within 5 h. This effect is attributed to the

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• overcome these problems [24]. Thus, encapsulation systems create a protective environment for metallodrugs, ensuring that they are delivered to the therapeutic site intact and limiting their interaction with healthy cells. In this way, nanoencapsulation systems drastically improve the efficacy and safety

• drug carriers with ligands that bind to specific receptors overexpressed on the surface of the target site [45]. There are notable differences between the surfaces of eukaryotic cells and pathogenic bacteria, which provides obvious advantages in active-targeting strategies. In Gram-positive bacteria

• receptors and ligands, as well as the number of interactions necessary to overcome the energy barrier for cellular uptake. Properly balancing these factors ensures efficient binding and internalization of the nanoparticles by the target cells [50][51]. For example, nanoparticles can be engineered to

Ferroptosis induction by engineered liposomes for enhanced tumor therapy

• Alireza Ghasempour,
• Mohammad Amin Tokallou,
• Mohammad Reza Naderi Allaf,
• Mohsen Moradi,
• Hamideh Dehghan,
• Mahsa Sedighi,
• Mohammad-Ali Shahbazi and
• Fahimeh Lavi Arab

Beilstein J. Nanotechnol. 2025, 16, 1325–1349, doi:10.3762/bjnano.16.97

• is defined by irregularities in the processes that control cell division, leading to the survival and rapid spread of cancerous cells. Despite significant advances in medical science and technology, cancer is still a disease with limited therapeutic options. Metastasis and recurrence of cancer lead

• to high disability and mortality, and the exact mechanisms are still unclear. Current chemotherapy faces challenges, including non-specificity, toxicity to healthy cells, the development of stem-like cells, and the progression of multidrug resistance [1]. Drug resistance is a major obstacle in cancer

• therapy and is closely linked to alterations in cancer metabolism [2][3][4]. Changed metabolic pathways allow cancer cells to grow faster than usual, adapt to restricted nutrient conditions, and develop drug resistance [3]. There is still a gap in the efficacy of various cancer therapies despite numerous

Acrocomia aculeata oil-loaded nanoemulsion: development, anti-inflammatory properties, and cytotoxicity evaluation

• Verónica Bautista-Robles,
• Hady Keita,
• Edgar Julián Paredes Gamero,
• Layna Tayná Brito Leite,
• Jessica de Araújo Isaías Muller,
• Mônica Cristina Toffoli Kadri,
• Ariadna Lafourcade Prada and
• Jesús Rafael Rodríguez Amado

Beilstein J. Nanotechnol. 2025, 16, 1277–1288, doi:10.3762/bjnano.16.93

• ) was used as a positive control, whereas cells from the culture without the nanoemulsion served as a negative control. Different concentrations of the nanoemulsion (1.65, 3.30, 6.60, 12.5, 25, 50, and 100 μg/mL) were added to the cultured cells and kept in contact for 24 h. Assays were performed in

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• emerged as an exciting frontier in the field of biomedicine. These nanoparticles can emulate essential biological functions, drawing from an abundant reservoir of cellular capabilities. This includes engaging in biological binding, precise homing to tumor sites, and interaction with immune cells. These

• utility, biomimetic nanoparticles hold great promise for advancing the field of cancer treatment. Keywords: biomimetic nanoparticles; homotypic binding; nanomaterials; targeted drug delivery; tumor therapy; Introduction Cancer is a complex disease, which involves numerous cells and their crosstalk with

• surrounding environment, including immunosuppression in T cells via PD-1/PD-L1 axis, recruitment of stem cells via CXCR4/CXCL2 chemokine axis, maturation of immune cells via membrane interactions, and various other physical/chemical interactions, uncover the emergence of cell membrane-based drug delivery

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• , comprising high biocompatibility and three-dimensional conformation. Their structural organization simulates the architecture of living tissues, allowing the flux of nutrients, oxygen, metabolites, and even whole cells. As a result, hydrogels can be molded into body parts, being successfully employed in

• human pulmonary fibroblast derivative, the cells were cultured for seven days in a modified Eagle’s medium and then decellularized by washing several times with PBS. Then a 7% aqueous PVA solution was added to the pulmonary fibroblast derivative. For the cross-linking of the solution, the freeze/thaw

• skin disease treatment, such as psoriasis [185][186], (enabling photoprotection [187]), and atopic dermatitis [62][188]. Hydrogels have also been used for site-specific delivery of antitumor agents in cutaneous tumor cells [189][190] as shown in Table 2. Chitosan hydrogels containing nanoencapsulated

Investigation of the solubility of protoporphyrin IX in aqueous and hydroalcoholic solvent systems

• Michelly de Sá Matsuoka,
• Giovanna Carla Cadini Ruiz,
• Marcos Luciano Bruschi and
• Jéssica Bassi da Silva

Beilstein J. Nanotechnol. 2025, 16, 1209–1215, doi:10.3762/bjnano.16.89

• , at a specific wavelength, PpIX absorbs energy and transfers it to molecular oxygen, generating reactive oxygen species (ROS). These ROS are highly toxic to cells, inducing oxidative damage in various biomolecules such as lipids, proteins and DNA, leading to cell death [6][7]. However, PpIX and other

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti

• Maria A. A. Bertonceli,
• Vitor D. C. Cristo,
• Ivo J. Vieira,
• Francisco J. A. Lemos,
• Arnoldo R. Façanha,
• Raimundo Braz-Filho,
• Gustavo V. T. Batista,
• Luis G. M. Basso,
• Sérgio H. Seabra,
• Thalya S. R. Nogueira,
• Felipe F. Moreira,
• Arícia L. E. M. Assis,
• Antônia E. A. Oliveira and
• Kátia V. S. Fernandes

Beilstein J. Nanotechnol. 2025, 16, 1197–1208, doi:10.3762/bjnano.16.88

• , even when delivered via nanocomposites. The cytotoxicity analysis of natural rotenoids to HSF cells revealed no statistically significant differences in cell viability between the control group and the treatments with either in natura rotenoids or the CS/TPP-β-CD–rot nanocomposite (Figure 7; p > 0.05

• delivery system is biocompatible with HSF cells. Therefore, both free rotenoids and the CS/TPP-BCD rot formulation are safe for use at the tested concentration. Previous studies reported that synthetic insecticides, such as type II pyrethroids (deltamethrin, cyphenothrin, λ-cyhalothrin, cyfluthrin

• to rotenoids and to the CS/TPP–β-CD–rot nanocomposite was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The cells were cultured in 96-well plates at a density of 3 × 105 cells/mL. After adherence, the cells were treated with either in natura rotenoids

Mechanical stability of individual bacterial cells under different osmotic pressure conditions: a nanoindentation study of Pseudomonas aeruginosa

• Lizeth García-Torres,
• Idania De Alba Montero,
• Eleazar Samuel Kolosovas-Machuca,
• Facundo Ruiz,
• Sumati Bhatia,
• Jose Luis Cuellar Camacho and
• Jaime Ruiz-García

Beilstein J. Nanotechnol. 2025, 16, 1171–1183, doi:10.3762/bjnano.16.86

Influence of ion beam current on the structural, optical, and mechanical properties of TiO₂ coatings: ion beam-assisted vs conventional electron beam evaporation

• Agata Obstarczyk and
• Urszula Wawrzaszek

Beilstein J. Nanotechnol. 2025, 16, 1097–1112, doi:10.3762/bjnano.16.81

• , and good availability, TiO2 in the form of thin films is now widely used in the development of gas sensors, photodetectors, solar cells, memristors, and photocatalysts [1][12][15][16][17]. The area of application of titanium dioxide is also related to the crystal structure in which it occurs, that is

• , brookite, anatase, or rutile [16][17][18][19][20]. The rutile phase is the most stable structure of TiO2, while anatase is a metastable phase. Recently, the anatase phase of TiO2 has been particularly used in the production of solar cells and optical coatings. According to [17][18], titanium dioxide in the

Fabrication of metal complex phthalocyanine and porphyrin nanoparticle aqueous colloids by pulsed laser fragmentation in liquid and their potential application to a photosensitizer for photodynamic therapy

• Taisei Himeda,
• Risako Kunitomi,
• Ryosuke Nabeya,
• Tamotsu Zako and
• Tsuyoshi Asahi

Beilstein J. Nanotechnol. 2025, 16, 1088–1096, doi:10.3762/bjnano.16.80

• generation of reactive oxygen species by AlClPc, ZnPc, and PtOEP nanoparticles and the photocytotoxicity for PC12 and HeLa cells, and demonstrated that the nanoparticles can be used as photosensitizers for photodynamic therapy. Keywords: aqueous colloid; photosensitizer; phthalocyanine; pulsed laser

• against cancer cells was reported. However, conventional methods of producing nanoparticle colloids require organic solvents and excessive amounts of organic adjuvants, which may have other implications for research in pharmacological, photochemical, and medical applications, and also may interfere with

• polypropylene oxide (PPO) arranged in a triblock structure. Here, the stability in phosphate-buffered saline (PBS, pH 7.2), which is used widely in pharmacology and biomedical experiments, was examined. We evaluated the phototoxicity of the fabricated nanoparticle colloids in vitro against PC12 cells (a cell

Piezoelectricity of hexagonal boron nitrides improves bone tissue generation as tested on osteoblasts

• Sevin Adiguzel,
• Nilay Cicek,
• Zehra Cobandede,
• Feray B. Misirlioglu,
• Hulya Yilmaz and
• Mustafa Culha

Beilstein J. Nanotechnol. 2025, 16, 1068–1081, doi:10.3762/bjnano.16.78

• 10.3762/bjnano.16.78 Abstract Bone tissue, also known as bone, is a hard and specialized connective tissue consisting of various bone cells. Internally, it has a honeycomb-like matrix providing rigidity to the bone and a piezoelectric feature contributing to bone remodeling. Bone remodeling is a crucial

• process involving osteoblastic replacement and resorption by osteoclastic cells to maintain structural integrity and mechanical properties of the bone tissue as it grows. However, in cases of fracture or degeneration, the natural self-regeneration process or inherent piezoelectricity of the body may not

• with ultrasound (US) exposure. The results showed that the NMs are not cytotoxic at the concentrations tested and the migration ability and calcium deposit formation of the cells treated with the NMs and upon US exposure were significantly increased. These results demonstrate that the hBNs have the

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• [149][150][151][152][153]. Nanoarchitectonics is also used in the development of chemical catalysts [154][155][156][157][158], photocatalysts [159][160][161][162][163], sensors [164][165][166][167][168], biosensors [169][170][171][172][173], devices [174][175][176][177][178], solar cells [179][180][181

• ][182][183], fuel cells [184][185][186][187][188], batteries [189][190][191][192][193], supercapacitors [194][195][196][197][198], and other energy applications [199][200][201][202][203]. Furthermore, it is employed in environmental remediation [204][205][206][207][208], drug delivery [209][210][211

• and polar moieties can exhibit ferroelectric behavior and electronic carrier transport properties. The corresponding materials have been the subject of investigation for potential applications in electroluminescent devices, field-effect transistors, and solar cells [228][229][230][231][232]. To

A calix[4]arene-based supramolecular nanoassembly targeting cancer cells and triggering the release of nitric oxide with green light

• Cristina Parisi,
• Loredana Ferreri,
• Tassia J. Martins,
• Francesca Laneri,
• Samantha Sollima,
• Antonina Azzolina,
• Antonella Cusimano,
• Nicola D’Antona,
• Grazia M. L. Consoli and
• Salvatore Sortino

Beilstein J. Nanotechnol. 2025, 16, 1003–1013, doi:10.3762/bjnano.16.75

• cancer cells that overexpress the choline transporters, and it can be visualized thanks to the fluorescent tag. The fluorogenic unit also acts as a green light harvesting center, making the nanoassembly a photo-nanoreactor able to encapsulate a hydrophobic nitric oxide (NO) photodonor, otherwise

• purpose, we report the design and synthesis of the cationic calix[4]arene 1 and its supramolecular nanoassembly with the blue-light-activatable nitroso-derivative NOPD 2 (Scheme 1). We show that (i) 1 self-assembles in water medium into nanoaggregates able to internalize into cancer cells selectively and

• specifically target cancer cells overexpressing choline transporters and, after encapsulation of the NOPD 2, stimulate NO release through a green-light-triggered photosensitization process. Results and Discussion Design and synthesis Calix[4]arene 1 integrates four choline moieties at the upper rim of the

Shape, membrane morphology, and morphodynamic response of metabolically active human mitochondria revealed by scanning ion conductance microscopy

• Eric Lieberwirth,
• Anja Schaeper,
• Regina Lange,
• Ingo Barke,
• Simone Baltrusch and
• Sylvia Speller

Beilstein J. Nanotechnol. 2025, 16, 951–967, doi:10.3762/bjnano.16.73

• , Rostock University Medical Center, 18057 Rostock, Germany 10.3762/bjnano.16.73 Abstract Mitochondrial network dynamics play a key role in enabling cells to adapt to environmental changes. Fusion and fission of mitochondria, as well as their contact with other organelles, are central processes

• . Consequently, the outer membrane, which separates the mitochondrion from the cytoplasm, has become a focus of investigation. We analysed metabolically active mitochondria from HeLa cells using scanning ion conductance microscopy to generate nanoscopically resolved, three-dimensional topographies. Our

• Mitochondria are essential organelles in eukaryotic cells, primarily responsible for energy supply. They have an endosymbiotic origin, resulting from the incorporation of an ancestral prokaryote into another prokaryotic host approximately 1.8 billion years ago [1][2][3]. This symbiotic relationship gave rise

Ar⁺ implantation-induced tailoring of RF-sputtered ZnO films: structural, morphological, and optical properties

• Manu Bura,
• Divya Gupta,
• Arun Kumar and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 872–886, doi:10.3762/bjnano.16.66

• displays [5], solar cells [6], and light-emitting diodes [7]. There are numerous methods for synthesizing ZnO films, including pulsed laser deposition, spray pyrolysis, radio frequency (RF) sputtering, and sol–gel techniques. Here RF sputtering is preferred over other methods because it provides high

• , although the variation in surface parameters and optical characteristics can significantly impact the applicability of ZnO films in semiconductors, spintronics, solar cells, and green energy industries [3][18]. This motivated us to investigate the emergence of Raman longitudinal optical modes and their

Insights into the electronic and atomic structures of cerium oxide-based ultrathin films and nanostructures using high-brilliance light sources

• Paola Luches and
• Federico Boscherini

Beilstein J. Nanotechnol. 2025, 16, 860–871, doi:10.3762/bjnano.16.65

• field of environmental remediation [9]. The related ability of the material to easily store and release oxygen also plays a key role in energy conversion technologies, including fuel cells and batteries [10][11]. Gas sensing applications of ceria-based materials are based on the modifications of the

• rationalized the observed high activity of the material in direct methanol fuel cells [37]. Regarding the Ni-CeO2−x(111) system, a study of the methanol reaction revealed that the strong metal–support interactions between Ni and CeO2 determines the high selectivity for CO2 production, instead of the formation

• soft X-ray range. Reaction cells with an ultrathin membrane that confines the gas in a narrow region extremely close to the sample surface were applied to the study of Cu- and Fe-doped cerium oxide films during thermal treatments in hydrogen at ambient pressure [58]. The combination of ambient pressure

Supramolecular hydration structure of graphene-based hydrogels: density functional theory, green chemistry and interface application

• Hon Nhien Le,
• Duy Khanh Nguyen,
• Minh Triet Dang,
• Huyen Trinh Nguyen,
• Thi Bang Tam Dao,
• Trung Do Nguyen,
• Chi Nhan Ha Thuc and
• Van Hieu Le

Beilstein J. Nanotechnol. 2025, 16, 806–822, doi:10.3762/bjnano.16.61

• advance nanoscale properties and nanotechnology applications. Keywords: antibacterial coating; bioinspired hydration; density functional theory; graphene-based hydrogel; supramolecular structure; Introduction Biological cells are assemblies of biomolecules that are hydrated with water molecules. The

• . High water content and large spacing distance in the hydrogel structure are key factors that prevent van der Waals and π–π interactions between graphene-based sheets. Figure 2b depicts the hydrated assembly of biological cells in nature. The natural hydrated structure includes intracellular water, cell

• hydrogel in Figure 2a is biomimetic to the natural system of biological cells described in Figure 2b. Hydration shells on GO-SG-ZH nanosheets, particularly the first interfacial water layer, generate hydration forces to maintain intersheet distances and nanoscale structures in the artificial system. The

Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

• Demian van Straten,
• Luuk van de Schepop,
• Rowan Frunt,
• Pieter Vader and
• Raymond M. Schiffelers

Beilstein J. Nanotechnol. 2025, 16, 740–748, doi:10.3762/bjnano.16.57

• internalization of RNA molecules by target cells [23]. Several LNP encapsulated RNA-based therapeutics have achieved approval by the United States Food and Drug Administration (FDA) [24], including patisiran/Onpattro for the treatment of hereditary transthyretin amyloidosis. Onpattro LNPs are administered

• intravenously after which they are dependent on the adsorption of the plasma protein apolipoprotein E (ApoE) to their surface to efficiently target LDL-receptor expressing cells in the liver and deliver the siRNA cargo [25][26]. As the protein corona seems to play a pivotal role in LNP tissue distribution and

• (Peprotech), and 50 nM hydrocortisone (Sigma), in flasks coated with 0.1% gelatin (Merck). All cells were cultured at 37 °C with 5% CO2. Cell lines were transformed to express the dual luciferase system as described by Evers et al. [28]. Briefly, cell lines were transfected with a pHAGE2-PGK-FFluc-SV40-Rluc

Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor

• Tina Friedenauer,
• Maximilian Spellauge,
• Alexander Sommereyns,
• Verena Labenski,
• Tuba Esatbeyoglu,
• Christoph Rehbock,
• Heinz P. Huber and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55

• particle surface and quantified regarding feedstock mass concentration and nutraceutical type. Cytotoxicity in HepG2 cancer cells was significantly reduced in cells treated with laser-processed curcumin in comparison to unirradiated curcumin controls, and antioxidant effects were proven, ensuring high

• greater intracellular uptake and increased cytotoxicity on rat C6 glioma cells [36]. Laser-generated nanoscale cinnamon was also synthesized and showed enhanced antibacterial activity against Gram-negative and Gram-positive bacteria after particle size reduction compared to the unirradiated educt [37

• molecules [75][76]. The effect of curcumin on cancer cells has been frequently examined, and two potentially contradictory effects are frequently discussed. On the one hand, curcumin nanoparticles are said to be more cytotoxic to cancer cells like HepG2 than the corresponding microparticle formulations [77

Nanostructured materials characterized by scanning photoelectron spectromicroscopy

• Matteo Amati,
• Alexey S. Shkvarin,
• Alexander I. Merentsov,
• Alexander N. Titov,
• María Taeño,
• David Maestre,
• Sarah R. McKibbin,
• Zygmunt Milosz,
• Ana Cremades,
• Rainer Timm and
• Luca Gregoratti

Beilstein J. Nanotechnol. 2025, 16, 700–710, doi:10.3762/bjnano.16.54

• one-transistor-one-resistor cells with minimal footprint [25] can be realized. Optimizing nanowire diameter and distance further enhances the strong light adsorption of III–V materials, resulting in nanowire-based solar cells of high efficiency [26]. While such nanowire-based devices are highly

• high spatial resolution. We correlate that to the chemical surface composition, distinguishing between surface and bulk effects on the path towards improved surface properties of nanowire solar cells with further enhanced efficiency. Furthermore, they demonstrate the large suitability of SPEM for

The impact of tris(pentafluorophenyl)borane hole transport layer doping on interfacial charge extraction and recombination

• Konstantinos Bidinakis and
• Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 678–689, doi:10.3762/bjnano.16.52

• in solar cells based on these materials. To do so on operating solar cells, we created samples with exposed cross-sections and examined their potential profile distributions with Kelvin probe force microscopy (KPFM), implementing our comprehensive measurement protocol. Using the Lewis acid tris

• ; hole transport layer doping; Kelvin probe force microscopy; perovskite solar cells; Introduction Perovskite solar cells (PSCs) are a promising class of photovoltaic material that exhibits high power conversion efficiencies and relies on a low-cost solution-processed fabrication method [1][2][3][4]. At

• the core of their success lies the perovskite absorber material, which exhibits impressive bulk properties, such as long carrier lifetimes and low recombination rates [5][6][7][8]. However, the granular nature of perovskites and the layered structure of their solar cells, introduce complications such

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

• Teissir Ben Ammar,
• Naji Kharouf,
• Dominique Vautier,
• Housseinou Ba,
• Nivedita Sudheer,
• Philippe Lavalle and
• Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

• , demonstrating no cytotoxicity to periodontal ligament cells up to 200 µg·mL−1 while promoting cellular adhesion and maintaining chromatin integrity. Overall, because of its favorable biocompatibility FLG–TA holds promise as a novel biomaterial for dental applications. Keywords: antioxidant properties

• ; biocompatibility; dental applications; few layered graphene–tannic acid biocomposite (FLG–TA); periodontal ligament cells (PDL); Introduction Dental diseases remain a global health challenge [1]. Dental biomaterials are crucial in both therapeutic and preventive strategies, with nanotechnology emerging as a

• microhardness without compromising biocompatibility [7]. In another work, the formulation of an injectable calcium phosphate cement–chitosan–graphene oxide (GO) composite was found to be effective. This composite fostered the proliferation of human dental pulp stem cells [8]. Despite these promising findings

Nanoscale capacitance spectroscopy based on multifrequency electrostatic force microscopy

• Pascal N. Rohrbeck,
• Lukas D. Cavar,
• Franjo Weber,
• Peter G. Reichel,
• Mara Niebling and
• Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 637–651, doi:10.3762/bjnano.16.49

• study materials such as perovskite solar cells [18][19][20] and Li-ion batteries [21][22][23]. AFM enables simultaneous acquisition of topographic and electronic data by applying AC or DC voltages across the tip–sample gap, allowing for the detection of capacitive forces [24][25] or contact potential