Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• serum samples. The capture probe is an EGFR aptamer with thiol modification, and the signal probe is an anti-EGFR antibody. This multifunctional cellular probe specifically recognizes and binds to EGFR on the cell surface, inducing the formation of probe aggregates that significantly enhance resonance

• this system, resulting in false positive diagnoses. Furthermore, the diagnostic accuracy achieved through resonance RRS analysis may be inferior to that of enzyme-linked immunosorbent assay methodologies. 3.2 Fluorescent aptasensors Chen et al. [56] screened and optimized the sequence by Cell-SELEX to

Few-photon microwave fields for superconducting transmon-based qudit control

• Irina A. Solovykh,
• Andrey V. Pashchenko,
• Natalya A. Maleeva,
• Nikolay V. Klenov,
• Olga V. Tikhonova and
• Igor I. Soloviev

Beilstein J. Nanotechnol. 2025, 16, 1580–1591, doi:10.3762/bjnano.16.112

• -dependent populations of transmon levels at optimal points. The results are shown in Figure 4. In the resonance case (Figure 4a), the excitation of high-energy transmon states is strongly suppressed due to significant influence of the Kerr nonlinearity (K = 9.6). However, it is clearly seen that the

• was chosen to be ω0/2π = 5.348 GHz to provide simultaneously strong coupling with the quantum field and optimal detuning from the resonance. In addition, this frequency determines the total length of the system, that is, 2l = 11.101 mm. Let us discuss the limitations on the values of the physical

Cross-reactivities in conjugation reactions involving iron oxide nanoparticles

• Shoronia N. Cross,
• Katalin V. Korpany,
• Hanine Zakaria and
• Amy Szuchmacher Blum

Beilstein J. Nanotechnol. 2025, 16, 1504–1521, doi:10.3762/bjnano.16.106

• [51][52]. In the context of magnetic resonance imaging, small molecule ligands also offer advantages over thicker, polymeric coatings as superior contrast agents [53][54][55]. To investigate amine cross-reactivities, we use propargylamine (PPA, Figure 1c) and a series of primary amine-containing dyes

Nanomaterials for biomedical applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Filippo Pierini,
• Seda Kizilel and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 1499–1503, doi:10.3762/bjnano.16.105

• contrast agents in magnetic resonance imaging (MRI) process [19]. There is more clarity in MRI images due to these nanoparticles, which help doctors to see even the smallest details in tissues and organs [20]. Apart from imaging, magnetic nanoparticles are now used in biosensors and lab-on-a-chip devices

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• approximately 15 to 40 nanoparticles per μm2. The hybrid materials exhibited plasmon resonance absorption of the Au NPs. Shorter EPD times maintained the properties of graphene, while longer deposition times resulted in the conversion of graphene to graphene oxide due to its electrochemical oxidation [132

Photochemical synthesis of silver nanoprisms via green LED irradiation and evaluation of SERS activity

• Tuan Anh Mai-Ngoc,
• Nhi Kieu Vo,
• Cong Danh Nguyen,
• Thi Kim Xuan Nguyen and
• Thanh Sinh Do

Beilstein J. Nanotechnol. 2025, 16, 1417–1427, doi:10.3762/bjnano.16.103

• candidates for surface-enhanced Raman scattering (SERS) due to their strong localized surface plasmon resonance and sharp tip geometry. In this study, AgNPrs were synthesized through a photochemical method by irradiating spherical silver nanoparticle seeds with 10 W green light-emitting diodes (LEDs; 520

• resonance (SPR) exhibited by AgNPrs significantly contributes to SERS enhancement by amplifying local electromagnetic fields. This makes AgNPrs ideal candidates for SERS-based sensing applications [1]. Numerous studies have focused on the fabrication of SERS-active substrates by depositing AgNPrs onto

• –vis spectrum exhibited a single absorption peak at 402 nm, characteristic of the in-plane dipole (IPD) resonance of spherical silver nanoparticles. The solution retained its yellow color, indicating that the seed morphology remained largely unchanged and that no formation of anisotropic silver

Synthesis and antibacterial properties of nanosilver-modified cellulose triacetate membranes for seawater desalination

• Lei Wang,
• Shizhe Li,
• Kexin Xu,
• Wenjun Li,
• Ying Li and
• Gang Liu

Beilstein J. Nanotechnol. 2025, 16, 1380–1391, doi:10.3762/bjnano.16.100

• nanomaterials can be engineered to optimize their antimicrobial activity, making them versatile tools in the development of advanced membrane technologies. Quantum effects, such as localized surface plasmon resonance in metallic nanoparticles, can further enhance antimicrobial properties by generating reactive

• and Discussion Structure of membrane material To verify the target structure of the synthesized material, Fourier-transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (NMR) were conducted, with the spectra depicted in Figure 1 and Figure 2, respectively. The FTIR bands

Ferroptosis induction by engineered liposomes for enhanced tumor therapy

• Alireza Ghasempour,
• Mohammad Amin Tokallou,
• Mohammad Reza Naderi Allaf,
• Mohsen Moradi,
• Hamideh Dehghan,
• Mahsa Sedighi,
• Mohammad-Ali Shahbazi and
• Fahimeh Lavi Arab

Beilstein J. Nanotechnol. 2025, 16, 1325–1349, doi:10.3762/bjnano.16.97

• . Other characterization techniques include nuclear magnetic resonance (NMR) spectroscopy to study membrane fluidity and phase transitions, fluorescence spectroscopy for investigating drug–liposome interactions, and capillary electrophoresis to analyze liposome–drug interactions and drug release [110][121

Wavelength-dependent correlation of LIPSS periodicity and laser penetration depth in stainless steel

• Nitin Chaudhary,
• Chavan Akash Naik,
• Shilpa Mangalassery,
• Jai Prakash Gautam and
• Sri Ram Gopal Naraharisetty

Beilstein J. Nanotechnol. 2025, 16, 1302–1315, doi:10.3762/bjnano.16.95

• medium) and εm = (n + ik)2, n is the real part of the refractive index of the metal, and k is the coefficient of extinction. According to this model, the periodicity should exhibit an increasing trend with wavelength when there is no resonance. However, the experiments presented in this work show some

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• , high efficiency, and better tissue penetration. They developed small Fe@Fe3O4-DHCA nanoparticles (≈14 nm) and coated them with macrophages (RAW267.4 cells) for magnetic resonance imaging (MRI) and MHT of solid tumors. The Fe@Fe3O4-DHCA NPs showed accumulation in tumor cells resulting in enhanced MRI

Deep learning for enhancement of low-resolution and noisy scanning probe microscopy images

• Samuel Gelman,
• Irit Rosenhek-Goldian,
• Nir Kampf,
• Marek Patočka,
• Maricarmen Rios,
• Marcos Penedo,
• Georg Fantner,
• Amir Beker,
• Sidney R. Cohen and
• Ido Azuri

Beilstein J. Nanotechnol. 2025, 16, 1129–1140, doi:10.3762/bjnano.16.83

• scan direction (here, x). However, in some modes, such as peak force and photothermal off-resonance tapping as used here, unless the data is significantly oversampled, decreasing the number of pixels in both x and y scan directions will lower acquisition time proportionately. We therefore sample here

• 52 pairs of low- and high-resolution images of a Celgard® 2400 membrane (Celgard, LLC - North Carolina, USA). Images of 5 μm × 5 µm were captured at 8–10 Hz scanning speed, using a fast-scan AFM system, operated by using photothermal off-resonance (at 10 kHz) tapping [35] and small cantilevers, which

Piezoelectricity of hexagonal boron nitrides improves bone tissue generation as tested on osteoblasts

• Sevin Adiguzel,
• Nilay Cicek,
• Zehra Cobandede,
• Feray B. Misirlioglu,
• Hulya Yilmaz and
• Mustafa Culha

Beilstein J. Nanotechnol. 2025, 16, 1068–1081, doi:10.3762/bjnano.16.78

• microscopy (PFM, Nanomagnetic Instruments, UK) was applied to evaluate nanoscale piezoelectric behavior using self-aligned conducting EFM probes with a spring constant of 2.8 N/m and a resonance frequency of 75 kHz. In vitro analyses To investigate the influence of hBNs and BaTiO3 with US therapy on

Time-resolved probing of laser-induced nanostructuring processes in liquids

• Maximilian Spellauge,
• David Redka,
• Mianzhen Mo,
• Changyong Song,
• Heinz Paul Huber and
• Anton Plech

Beilstein J. Nanotechnol. 2025, 16, 968–1002, doi:10.3762/bjnano.16.74

• other than purely thermal effects. Among these are electron emission [109], near-field forces of the plasmon resonance on the surface, pressure effects due to an expanding electron gas [25][27], or spatial spreading of fast electrons [110][111]. In general, with femtosecond excitation a large fraction

• approaches [115]. The subsequent pressure and temperature conditions emanate from the close interaction of the excited particles with the medium. The width of the SPR reflects the coherence time of this oscillation. This dephasing time amounts to a few femtoseconds, leading to a plasmon resonance width of

• -field ablation [26][52]. While electronic excitation is easily detected by TAS, the various structural responses of NPs are weaker and ambiguous in TAS. While elastic oscillations of NPs are identified in periodic modulations of the plasmon resonance due to the change of electron density, other

Synthesis of biowaste-derived carbon-dot-mediated silver nanoparticles and the evaluation of electrochemical properties for supercapacitor electrodes

• Navya Kumari Tenkayala,
• Chandan Kumar Maity,
• Md Moniruzzaman and
• Subramani Devaraju

Beilstein J. Nanotechnol. 2025, 16, 933–943, doi:10.3762/bjnano.16.71

• evidenced from the progressive color change of the solution as shown by surface plasmon resonance (SPR). Structural and morphological analysis The optical properties of PG-CDs and PG-CDs-AgNPs were studied using UV–visible spectroscopy and photoluminescence (PL) spectroscopy. An absorption peak at 275 nm

Heat-induced transformation of nickel-coated polycrystalline diamond film studied in situ by XPS and NEXAFS

• Olga V. Sedelnikova,
• Yuliya V. Fedoseeva,
• Dmitriy V. Gorodetskiy,
• Yuri N. Palyanov,
• Elena V. Shlyakhova,
• Eugene A. Maksimovskiy,
• Anna A. Makarova,
• Lyubov G. Bulusheva and
• Aleksandr V. Okotrub

Beilstein J. Nanotechnol. 2025, 16, 887–898, doi:10.3762/bjnano.16.67

• (Figure 1a). In the AEY spectra of both films, the smoother shape of the σ*(sp3) resonance and the shallower dip suggest to the presence of structural disorders on the surface of diamond films (Figure 1b). The amount of these disorders in Ni-PCD is higher than that in PCD. This result confirms previous

• a high degree of local crystallinity (i.e., high ordering of carbon atoms in the honeycomb network) and their C K-edge spectra contain a narrow and intense π*(sp2)-resonance [41][42]. However, the rather low intensity of the π*(sp2)-resonance in the spectrum of the annealed Ni-PCD film indicates

• that annealing of polycrystalline films on average leads to the formation of structurally highly disordered forms of sp2 carbon layers. The AEY spectra of the annealed PCD and Ni-PCD films exhibit an additional pronounced feature at about 284.0 eV, which can also be assigned to π*(sp2)-resonance and

Insights into the electronic and atomic structures of cerium oxide-based ultrathin films and nanostructures using high-brilliance light sources

• Paola Luches and
• Federico Boscherini

Beilstein J. Nanotechnol. 2025, 16, 860–871, doi:10.3762/bjnano.16.65

• configurations at 110 and 125 eV, respectively [23][25][26][27][28]. Figure 1 reports valence band spectra from an ultrathin cerium oxide film before and after ultrahigh vacuum (UHV) annealing at 600 °C, acquired at the two resonant energies. Using a photon energy at the Ce4+-related resonance (110 eV), the

•  3a shows a sequence of μ-XPS valence band spectra acquired using a photon at the Ce3+-related Ce 4d→Ce 4f1 resonance (hν = 120.8 eV) on a Ce0.4Zr0.6O2−x film upon removal and reintroduction of oxygen (PO2 = 1 × 10−7 mbar) in the experimental chamber. When oxygen is removed (red spectrum in Figure 3b

• N4,5 XANES acquired using synchrotron radiation on the composite film and two reference spectra of Ce4+ and Ce3+ from literature [64]. Also, it evidences the photon energies used for the pump–probe FEL measurements. The transient XANES intensity after pumping the Ag plasmonic resonance, exhibits an

Synchrotron X-ray photoelectron spectroscopy study of sodium adsorption on vertically arranged MoS₂ layers coated with pyrolytic carbon

• Alexander V. Okotrub,
• Anastasiya D. Fedorenko,
• Anna A. Makarova,
• Veronica S. Sulyaeva,
• Yuliya V. Fedoseeva and
• Lyubov G. Bulusheva

Beilstein J. Nanotechnol. 2025, 16, 847–859, doi:10.3762/bjnano.16.64

• 291.8 eV (Figure 2b), which are attributed to the electron transitions from the C 1s core levels to the π* and σ* C=C states in the graphitic structure, respectively [42]. The rather sharp shape of the π* resonance indicates the graphitic-like structure of the PyC film. Weak features appearing between

• the π* and σ* resonances suggest that the PyC film is slightly functionalized with oxygen- and/or hydrogen-containing groups. The spectrum of the PyC-MoS2 film almost repeats the shape of the spectrum of the PyC film. A slight decrease in the intensity of the π* resonance and an increase in the

• intensity in the regions before and after the π* resonance at 284–285 eV and 286–289 eV can be associated with the interaction between PyC and MoS2 components [43]. The shift of the C K-edge spectrum of the PyC-MoS2 film toward lower photon energies corresponds to the electron density transfer from the

Changes of structural, magnetic and spectroscopic properties of microencapsulated iron sucrose nanoparticles in saline

• Sabina Lewińska,
• Pavlo Aleshkevych,
• Roman Minikayev,
• Anna Bajorek,
• Mateusz Dulski,
• Krystian Prusik,
• Tomasz Wojciechowski and
• Anna Ślawska-Waniewska

Beilstein J. Nanotechnol. 2025, 16, 762–784, doi:10.3762/bjnano.16.59

• the dissolution time. Electron paramagnetic resonance (EPR) studies performed on the completely dissolved sample revealed that some of the Fe3+ ions became paramagnetic, while the rest remained exchange coupled into clusters. The nonintentional manganese contamination was determined using EPR in the

• transmission electron microscopy (TEM). Composition studies using XRD, magnetic properties using dc and ac magnetometry, and extensive spectral analysis using Fourier-transform infrared spectroscopy (FTIR), Raman, and electron paramagnetic resonance (EPR) were also performed. Considering that the AB-Fortis

Thickness dependent oxidation in CrCl₃: a scanning X-ray photoemission and Kelvin probe microscopies study

• Shafaq Kazim,
• Rahul Parmar,
• Maryam Azizinia,
• Matteo Amati,
• Muhammad Rauf,
• Andrea Di Cicco,
• Seyed Javid Rezvani,
• Dario Mastrippolito,
• Luca Ottaviano,
• Tomasz Klimczuk,
• Luca Gregoratti and
• Roberto Gunnella

Beilstein J. Nanotechnol. 2025, 16, 749–761, doi:10.3762/bjnano.16.58

• cantilever coated with Pt at the resonance frequency of 68 kHz with an elastic constant of 1–5 N/m (AppNano) and doped diamond tips with 120 kHz and 8 N/m elastic constant (ADAMA). Kelvin probe force microscopy images were taken via double passage before and after applying an electric field by elevating the

The impact of tris(pentafluorophenyl)borane hole transport layer doping on interfacial charge extraction and recombination

• Konstantinos Bidinakis and
• Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 678–689, doi:10.3762/bjnano.16.52

• lock-in amplifier (Zurich Instruments), in an argon atmosphere glove box (less than 1% ppm O2 and negligible humidity). The cantilever used was SCM PIT V2 (resonance frequency: 75 kHz, spring constant: 3 N/m, Bruker). The scan rate of the measurement was 0.5 Hz. To increase the reliability of our data

Nanoscale capacitance spectroscopy based on multifrequency electrostatic force microscopy

• Pascal N. Rohrbeck,
• Lukas D. Cavar,
• Franjo Weber,
• Peter G. Reichel,
• Mara Niebling and
• Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 637–651, doi:10.3762/bjnano.16.49

• method for nanoscale capacitance characterization at arbitrary frequencies above the second cantilever resonance. Besides a high spatial resolution, the key advantage of the multifrequency approach of MFH-EFM is that it measures the second-order capacitance gradient at almost arbitrary frequencies

• ][71] as well as a heterodyne-based EFM mode [59][72][73][78]. By using a low-frequency modulation of a high-frequency electrostatic drive, the response can be picked up either via a frequency shift or by an electrostatic response at one of the cantilever’s resonance frequencies. Thus, the dielectric

• arbitrary frequencies above the second cantilever resonance. Our approach measures the second capacitance gradient, enhancing localization by minimizing stray capacitance contributions [65]. This method enables high-frequency capacitance gradient spectroscopy without requiring specialized equipment beyond a

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

• Shiwani Randhawa,
• Trilok Chand Saini,
• Manik Bathla,
• Rahul Bhardwaj,
• Rubina Dhiman and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

• ., CSF and blood tests [54]. Researchers have also employed the surface plasmon resonance (SPR) of citric acid-coated AuNPs, to specifically detect and quantify Aβ40 oligomers, as the SPR absorption band of AuNPs was found to be sensitive to the presence of AβOs [55]. While exploring the range of AβO

N₂⁺-implantation-induced tailoring of structural, morphological, optical, and electrical characteristics of sputtered molybdenum thin films

• Usha Rani,
• Kafi Devi,
• Divya Gupta and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 495–509, doi:10.3762/bjnano.16.38

• production of Mo nanoparticles and the subsequent increase in surface plasmon resonance or interband transitions. As-deposited molybdenum thin films deposited at room temperature typically exhibit a smooth surface and crystalline structure. The absorbance of molybdenum thin films increases with increasing

• film thickness and peaks between 300 and 700 nm, corresponding to the localized surface plasmon resonance (LSPR) of molybdenum nanoparticles [45][46]. The formation of defects through ion irradiation increased the scattering of light and absorption within the film, resulting in enhanced overall

• of the nanoparticles, influencing their resonance properties and, subsequently, the absorbance spectrum [49]. Furthermore, the alteration in peak location indicates an increased number of nanoparticles or a modification in their size distribution resulting from damage caused by ion implantation

Performance optimization of a microwave-coupled plasma-based ultralow-energy ECR ion source for silicon nanostructuring

• Joy Mukherjee,
• Safiul Alam Mollick,
• Tanmoy Basu and
• Tapobrata Som

Beilstein J. Nanotechnol. 2025, 16, 484–494, doi:10.3762/bjnano.16.37

• generating ion beams in a microwave-coupled plasma-based ultralow-energy electron cyclotron resonance ion source, generally used for nanostructuring solid surfaces. The investigation focuses on developing, accelerating, and extracting Ar ions from a magnetron-coupled plasma cup utilizing a three-grid ion

• various ions using gaseous plasma, the ion sources can be classified in direct current (DC)-operated ion sources, radio frequency discharge ion sources, and microwave-based electron cyclotron resonance (ECR) ion sources, as well as electron bombardment, charge exchange, and laser-driven ion sources [17

• spatial formation of silicon oxide changes the reflectivity. Also, nanopatterned silicon surfaces can be an alternative for memory devices. Conclusion In this manuscript, the intricacies of an ultralow-energy magnetron-based electron cyclotron resonance (ECR) ion source are studied systematically by

Effect of additives on the synthesis efficiency of nanoparticles by laser-induced reduction

• Rikuto Kuroda,
• Takahiro Nakamura,
• Hideki Ina and
• Shuhei Shibata

Beilstein J. Nanotechnol. 2025, 16, 464–472, doi:10.3762/bjnano.16.35

• the change in the absorption peak at 520 nm in the UV–vis absorption spectrum caused by the localized surface plasmon resonance (LSPR) of the Au nanoparticles as a function of the laser irradiation time. The black line shows the change in absorbance for the solution without IPA, and the red line shows