Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

• Douglas Dourado,
• Thayse Silva Medeiros,
• Éverton do Nascimento Alencar,
• Edijane Matos Sales and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

• in the spleen of mice was around 60% for free-UA and close to 90% for NLC-UA. Confocal microscopy images proved the cell uptake of NLC into macrophages. Metal nanoparticles are also excellent alternatives for carrying antileishmanial drugs [71]. Almayouf et al. produced silver nanoparticles (Ag-NP

• synthesized curc-coated silver nanoparticles (curc-AgNPs) for the treatment of cutaneous leishmaniasis [124]. Curc-AgNPs presented a spherical shape, 32 nm of diameter, and a zeta potential of −19.8 mV. This nanoformulation prevented the in vitro growth of L. major promastigotes and inhibited their viability

• , the found activity may be mostly attributed to curc-coated NPs. The same behavior was observed in Miltefosine-AgNPs developed by Kalangi and collaborators. Silver nanoparticles alone (50 μM) did not demonstrate an antileishmanial effect on the promastigote stage of the Leishmania parasite. However

Silver-based SERS substrates fabricated using a 3D printed microfluidic device

• Phommachith Sonexai,
• Minh Van Nguyen,
• Bui The Huy and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2023, 14, 793–803, doi:10.3762/bjnano.14.65

• method limits the amount of precursor chemicals and enables the sequential flow of droplets, resulting in silver nanoparticles of uniform shape and size. We investigated the effects of different synthesis conditions on the size distribution, dispersity, and LSPR wavelength of the silver nanoparticles

• treated at 90 °C for 5 min on a hot plate. Following this step, silicon tubes were joined to the inlets of the microfluidic device using Loctite superglue. Synthesis of silver nanoparticles The droplet-based microfluidic device was used to synthesize Ag NPs. These droplets enable the uniform distribution

• aqueous solutions and oil, respectively. Synthesis of silver nanoparticles Different molar ratios of silver nitrate to sodium borohydride were used to produce Ag nanoparticles in the microfluidic device at room temperature, with flow rates of 20 and 80 µL/min for the aqueous solutions and oil

Silver nanoparticles loaded on lactose/alginate: in situ synthesis, catalytic degradation, and pH-dependent antibacterial activity

• Nguyen Thi Thanh Tu,
• T. Lan-Anh Vo,
• T. Thu-Trang Ho,
• Kim-Phuong T. Dang,
• Van-Dung Le,
• Phan Nhat Minh,
• Chi-Hien Dang,
• Vinh-Thien Tran,
• Van-Su Dang,
• Tran Thi Kim Chi,
• Hieu Vu-Quang,
• Radek Fajgar,
• Thi-Lan-Huong Nguyen,
• Van-Dat Doan and
• Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2023, 14, 781–792, doi:10.3762/bjnano.14.64

• Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam Faculty of Chemical Engineering, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam 10.3762/bjnano.14.64 Abstract We present the in situ synthesis of silver nanoparticles (AgNPs) through

• activity. These findings suggest that this nanocomposite has the potential to be tailored for specific applications in environmental and medicinal treatments, making it a highly promising material. Keywords: alginate; bacterial activity; catalysis; lactose; silver nanoparticles; synthesis; Introduction

• Silver nanoparticles (AgNPs) have raised significant interest for their wide range of applications in biomedicine [1][2], treatment of wastewater [3][4], and catalysis [5][6]. The utilization of eco-friendly sources, such as plant extracts [7][8], fungi [9][10], and bacteria [11], for synthesizing AgNPs

A graphene quantum dots–glassy carbon electrode-based electrochemical sensor for monitoring malathion

• Sanju Tanwar,
• Aditi Sharma and
• Dhirendra Mathur

Beilstein J. Nanotechnol. 2023, 14, 701–710, doi:10.3762/bjnano.14.56

• dots and 3D bismuth oxyiodine hybrid hollow microspheres for the detection of chlopyrifos [26]. In 2020, Jiménez-López et al. worked on a fluorescent probe containing graphene quantum dots and silver nanoparticles for glyphosate detection [27]. In 2021, Xu Dan et al. developed a histidine

New trends in nanobiotechnology

• Pau-Loke Show,
• Kit Wayne Chew,
• Wee-Jun Ong,
• Sunita Varjani and
• Joon Ching Juan

Beilstein J. Nanotechnol. 2023, 14, 377–379, doi:10.3762/bjnano.14.32

• . Green synthesis methods were firstly applied for the biosynthesis of silver nanoparticles, along with silver chloride nanoparticles as there were chlorine salts in the pineapple peels which enable the formation of silver chloride. These nanoparticles were then characterized and tested regarding their

Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities

• Akif Hakan Kurt,
• Elif Berna Olutas,
• Fatma Avcioglu,
• Hamza Karakuş,
• Mehmet Ali Sungur,
• Cansu Kara Oztabag and
• Muhammet Yıldırım

Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31

• characterization of quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles (Ch/Q- and Ch/CA-Ag NPs), and their antibacterial and anticancer activities. The formation of Ch/Q- and Ch/CA-Ag NPs has been confirmed by ultraviolet–visible (UV–vis) spectroscopy, Fourier-transform

• , caffeic acid has also been reported to have antiviral, anticoagulant, anti-inflammatory, antibacterial, and anticancer activities [31][32][33][34]. Silver nanoparticles are an important example of different types of nanomaterials (copper, zinc, titanium, magnesium, gold, and alginate) that have been

• proven to be effective against bacteria and viruses [6][35]. Toxicologists extensively studied silver nanoparticles. Despite studies suggesting a toxicity of silver nanoparticles, this issue is still unresolved [36]. However, silver nanoparticles have become more popular in recent years due to their

Antimicrobial and mechanical properties of functionalized textile by nanoarchitectured photoinduced Ag@polymer coating

• Jessica Plé,
• Marine Dabert,
• Helene Lecoq,
• Sophie Hellé,
• Lydie Ploux and
• Lavinia Balan

Beilstein J. Nanotechnol. 2023, 14, 95–109, doi:10.3762/bjnano.14.11

• , and textiles need to be cleaned on a daily basis. Silver nanoparticles (AgNPs) possess well-documented antimicrobial properties and by combining them with a physical matrix, they can be applied to various surfaces to limit microbial contamination. With this in mind, a rapid and easy way to implement a

• [10]), gold [11][12], zinc oxide [13][14], and especially silver nanoparticles [15][16][17][18]. Silver is known to target peptidoglycane, a cellular membrane component of Gram-negative and -positive bacteria. If introduced directly in its ionic form, silver interacts with the electron-donor groups of

• replication [21]. Silver nanoparticles (AgNPs) have the added benefit of being ionic silver vessels, combining the latter’s antimicrobial properties with their own characteristics [16]. Pal et al. [22] demonstrated that triangular AgNPs seem to exhibit increased biocide activity compared to their spherical

In search of cytotoxic selectivity on cancer cells with biogenically synthesized Ag/AgCl nanoparticles

• Mitzi J. Ramírez-Hernández,
• Mario Valera-Zaragoza,
• Omar Viñas-Bravo,
• Ariana A. Huerta-Heredia,
• Miguel A. Peña-Rico,
• Erick A. Juarez-Arellano,
• David Paniagua-Vega,
• Eduardo Ramírez-Vargas and
• Saúl Sánchez-Valdes

Beilstein J. Nanotechnol. 2022, 13, 1505–1519, doi:10.3762/bjnano.13.124

• , Saltillo Coahuila, 25294, México 10.3762/bjnano.13.124 Abstract Green synthesis may be a useful approach to achieve selective cytotoxicity of silver nanoparticles on cancer cells and healthy cells. In this study, the concomitant biosynthesis of silver (Ag)/silver chloride (AgCl) nanoparticles from

• comparison to monocytes. Keywords: cancer cells; cytotoxic behavior; green synthesis; pineapple extract; silver chloride nanoparticles; silver nanoparticles; structural characterization; Introduction The study of metallic nanoparticle synthesis by green methods is gaining importance, especially in cases

• where plant extracts are used to synthesize nanoparticles. The nanoparticles can be produced in a simple, inexpensive, and scalable way, with low reaction time and in aqueous media. Since no toxic by-products are generated, these methods are eco-friendly [1]. Silver nanoparticles (AgNPs) are commonly

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• solvent casting process after the ACMCDs were supported by silver nanoparticles, employing them as both a reducing agent and a template. The nanocomposite antibacterial film is anticipated to have a lot of potential applications such as food packaging, water purification, and disinfecting sanitary

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• formation on rat calvaria defects indicate a strong healing effect and new bone formation on chitosan/absorbable collagen sponges [51]. Chitosan with metal nanomaterials for bone tissue engineering Chitosan–silver nanocomposites Silver nanoparticles (AgNPs) have gained much attention in bone-related implant

Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

A nonenzymatic reduced graphene oxide-based nanosensor for parathion

• Sarani Sen,
• Anurag Roy,
• Ambarish Sanyal and
• Parukuttyamma Sujatha Devi

Beilstein J. Nanotechnol. 2022, 13, 730–744, doi:10.3762/bjnano.13.65

• nanoribbons doped with silver nanoparticles, rGO doped with ZrO2, and CuO–TiO2 hybrid nanocomposites were proposed to detect methyl parathion [19][20][21][22]. Rajaji et al. (2019) modified glassy carbon electrodes with graphene oxide encapsulated 3D porous chalcopyrite (CuFeS2) nanocomposites to detect

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• , the substrate affinity of metal nanoparticles (1.53 mM) is comparable to that of natural lipase (1.27 mM). Metal ions, especially silver ions (Ag+), have been widely studied regarding antibacterial, antifungal, antiviral, anti-inflammatory, anti-angiogenic, and antitumor activities [63][64]. Silver

• nanoparticles (Ag NPs) hold great promise due to their broad-spectrum and robust antimicrobial properties [65]. The main mechanism is that Ag nanoparticles diffuse into cells and destroy cell walls [66]. However, Ag NPs are cytotoxic, which limits their application [67]. Song et al. [68] developed a broad

Assessment of the optical and electrical properties of light-emitting diodes containing carbon-based nanostructures and plasmonic nanoparticles: a review

• Keshav Nagpal,
• Erwan Rauwel,
• Frédérique Ducroquet and
• Protima Rauwel

Beilstein J. Nanotechnol. 2021, 12, 1078–1092, doi:10.3762/bjnano.12.80

• OLED has also been reported owing to the SPR of AgNP with an average size of 80 nm [48]. Silver nanoparticles were embedded in a PEDOT:PSS layer within the follwing device configuration: ITO (150 nm)/PEDOT:PSS (60 ± 10 nm)/AgNP/Alq3 (100 nm)/LiF (1 nm)/Al (100 nm). The PL emission intensity at 535 nm

The role of deep eutectic solvents and carrageenan in synthesizing biocompatible anisotropic metal nanoparticles

• Nabojit Das,
• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2021, 12, 924–938, doi:10.3762/bjnano.12.69

• of gold and silver nanoparticles. Surface plasmon resonance is an inherent property of plasmonic metal nanoparticles that is immensely employed as a tool for theranostics and is highly influenced by the size and shape of the nanoparticle [2]. The property of SPR has also been exploited for nanochips

• of nanotechnology. The use carrageenan in nanomaterial synthesis and application has been tabulated in Table 3 [32][110][111][112][113][114][115]. Carrageenan has been complexed with chitosan in a recent study, forming a composite for wound healing dressing. Silver nanoparticles, widely known for

• emerged as a promising candidate for industrial applications. Silver nanoparticles synthesized using carrageenan as a reducing and stabilizing agent showed promising results in removing organic dyes such as methylene blue and rhodamine B [111]. Magnetic iron nanoparticles were synthesized using κ-, ι-, or

Modification of a SERS-active Ag surface to promote adsorption of charged analytes: effect of Cu²⁺ ions

• Bahdan V. Ranishenka,
• Andrei Yu. Panarin,
• Irina A. Chelnokova,
• Sergei N. Terekhov,
• Peter Mojzes and
• Vadim V. Shmanai

Beilstein J. Nanotechnol. 2021, 12, 902–912, doi:10.3762/bjnano.12.67

• the electrostatic interaction between analyte molecules and silver nanoparticles (Ag NPs) on the intensity of surface-enhanced Raman scattering (SERS). For this, we fabricated nanostructured plasmonic films by immobilization of Ag NPs on glass plates and functionalized them by a set of differently

• ; oligonucleotides; porphyrin; silver nanoparticles; substrate modification; surface-enhanced Raman spectroscopy (SERS); Introduction Surface-enhanced Raman scattering (SERS) with its advantages of extreme sensitivity, high selectivity, and non-destructive nature has demonstrated great potential for the quick

Silver nanoparticles nucleated in NaOH-treated halloysite: a potential antimicrobial material

• Yuri B. Matos,
• Rodrigo S. Romanus,
• Mattheus Torquato,
• Edgar H. de Souza,
• Rodrigo L. Villanova,
• Marlene Soares and
• Emilson R. Viana

Beilstein J. Nanotechnol. 2021, 12, 798–807, doi:10.3762/bjnano.12.63

• 10.3762/bjnano.12.63 Abstract Despite all recent advances in medical treatments, infectious diseases remain dangerous. This has led to intensive scientific research on materials with antimicrobial properties. Silver nanoparticles (Ag-NPs) are a well-established solution in this area. The present work

• antimicrobial, and that it is possible to imbue a polymeric matrix with the antimicrobial properties of Ag-NPs. Keywords: antimicrobial activity; DIO coating; halloysite; nanocomposites; silver nanoparticles; Introduction The number of people dying from bacterial infections has been significantly reduced with

• cellular membrane and to disrupt internal cellular components, such as DNA [2][3][4][5][6]. Silver nanoparticles (Ag-NPs), in particular, are known for their antimicrobial properties and are one of the most extensively studied inorganic antimicrobial agents [7][8][9]. Early studies suggested that Ag-NPs

Silver nanoparticles induce the cardiomyogenic differentiation of bone marrow derived mesenchymal stem cells via telomere length extension

• Khosro Adibkia,
• Ali Ehsani,
• Asma Jodaei,
• Ezzatollah Fathi,
• Raheleh Farahzadi and
• Mohammad Barzegar-Jalali

Beilstein J. Nanotechnol. 2021, 12, 786–797, doi:10.3762/bjnano.12.62

• possible combination of stem cells and nanotechnology in the treatment of diseases. This study aims to investigate the in vitro effect of silver nanoparticles (Ag-NPs) on the cardiomyogenic differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs) through detection of cardiac markers. For

• ; cardiomyogenic differentiation; silver nanoparticles; telomere length; Wnt3/β-catenin signaling pathway; Introduction Cardiac disorders that eventually lead to heart failure cause an increased loss of cardiac cells. There is strong evidence that the progression of heart failure is associated with reduction in

• attention. Novel nanomaterials are being developed to improve disease treatment processes via biopharmaceutical molecules as well as the surface treatment of biomaterials [8][9]. Among nanoparticles (NPs), silver nanoparticles (Ag-NPs) are successfully commercialized due to their well-known antiseptic

Fate and transformation of silver nanoparticles in different biological conditions

• Barbara Pem,
• Marija Ćurlin,
• Darija Domazet Jurašin,
• Valerije Vrček,
• Rinea Barbir,
• Vedran Micek,
• Raluca M. Fratila,
• Jesus M. de la Fuente and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2021, 12, 665–679, doi:10.3762/bjnano.12.53

• de Zaragoza, Zaragoza 50009, Spain Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain 10.3762/bjnano.12.53 Abstract The exploitation of silver nanoparticles (AgNPs) in biomedicine represents more than one third of their overall application

• vivo settings. Keywords: animal tissue; biological media; nanoparticle aggregation; nanoparticle dissolution; nanoparticle reformation; silver nanoparticles; Introduction The global consumption of silver nanoparticles (AgNPs) has been steadily increasing in the last decade and estimated to reach over

• images of freshly synthesized silver nanoparticles (AgNPs) coated with PLL, AOT, or PVP dispersed in ultrapure water at a concentration of 10 mg Ag/L. Scale bars are 100 nm. TEM images of liver obtained from (a) untreated and (b) treated healthy male Wistar rats. The rats were treated orally with a daily

High-yield synthesis of silver nanowires for transparent conducting PET films

• Gul Naz,
• Hafsa Asghar,
• Muhammad Ramzan,
• Muhammad Arshad,
• Rashid Ahmed,
• Muhammad Bilal Tahir,
• Bakhtiar Ul Haq,
• Nadeem Baig and
• Junaid Jalil

Beilstein J. Nanotechnol. 2021, 12, 624–632, doi:10.3762/bjnano.12.51

• performance below that of ITO films. Hence, there is a need to modify this polyol method to produce extra-large and highly ordered silver nanowires to outperform ITO films. It is important to note that the polyol synthesis yields impurities in the form of silver nanoparticles [29]. These nanoparticles formed

• presence of silver nanoparticles in the solution. The ratio between AgNO3 and PVP used in the reaction greatly affects the synthesis of silver nanowires [32]. In the present reaction, the ratio of PVP to AgNO3 was 4:1. The solution was then cooled to room temperature by the addition of 30 mL DI water. The

• second peak at 373 nm is attributed to the longitudinal plasmon resonance of AgNWs. It is also noted that no other peak was observed, which shows that the final product was free from contamination of any other nanostructures, such as silver nanoparticles or nanocubes. The SEM results also confirm the

On the stability of microwave-fabricated SERS substrates – chemical and morphological considerations

• Limin Wang,
• Aisha Adebola Womiloju,
• Christiane Höppener,
• Ulrich S. Schubert and
• Stephanie Hoeppener

Beilstein J. Nanotechnol. 2021, 12, 541–551, doi:10.3762/bjnano.12.44

• on the SERS activity of the substrates and a carbonate buffer at pH 10 was found to even improve SERS performance. This study represents a guideline on the stability of microwave-fabricated SERS substrates or other SERS substrates consisting of non-stabilized silver nanoparticles for the application

• of different organic solvents and buffer solutions. Keywords: chemical stability; microwave synthesis; scanning electron microscopy; silver nanoparticles; surface-enhanced Raman spectroscopy; Introduction Surface-enhanced Raman spectroscopy (SERS) has been developed into a standard analytical tool

• glass capillaries or on scanning force microscopy tips) in a very economic and fast (less than five minutes) coating process. The formed substrates, which are coated with a monolayer of silver nanoparticles, have been demonstrated to be highly reproducible and to perform very well in the detection of

Surface-enhanced Raman scattering of water in aqueous dispersions of silver nanoparticles

• Paulina Filipczak,
• Krzysztof Hałagan,
• Jacek Ulański and
• Marcin Kozanecki

Beilstein J. Nanotechnol. 2021, 12, 497–506, doi:10.3762/bjnano.12.40

• Raman scattering (SERS) effect. In this work, we show the SERS effect for water molecules in the dispersion of silver nanoparticles (AgNPs) without any external electrical field. An enhancement factor was estimated to be (4.8 ± 0.8) × 106 for an excitation wavelength of 514.5 nm and for AgNPs with an

• effect weaker [20]. Silver nanoparticles (AgNPs) are gaining more and more popularity in various applications, such as electronics [22], photonics [23], and medicine [24]. Silver nanocolloids are also commonly used as an enhancing substrate in surface-enhanced Raman scattering (SERS) [25][26]. Since the

• , spontaneous and stimulated Raman surface enhancement of the signal of liquid water in an aqueous dispersion of silver nanoparticles [35]. High enhancement factors (in the magnitude of 106) were obtained for the results from both techniques. In this work, further investigations on the SERS effect for water

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• . Thenhipalam 673635, Kerala, India National Institute for Quality Control in Health, Oswaldo Cruz Foundation (INCQS, FIOCRUZ), Rio de Janeiro, RJ, Brazil 10.3762/bjnano.12.36 Abstract Recent studies with silver nanoparticles (AgNPs) and the history of silver metal as a broad-spectrum bactericidal and

• studies of this promising agent in nanomedicine and in clinical practice. Keywords: bactericidal agent; {111} facets; mechanism of action; silver ion; silver nanoparticles; quality control; virucidal agent; Review Introduction Silver is one of the oldest bactericidal agents in history and is also

• , advised Alexander the Great (335 BC) to add silver to his water [1][2][3]. Since then, the bactericidal effect of silver nanoparticles (AgNPs) has been studied and several experimental evidences have greatly improved the understanding of its mechanism and effects on the human body and on the environment