Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles – a fluorescence correlation spectroscopy study

• Pauline Maffre,
• Stefan Brandholt,
• Karin Nienhaus,
• Li Shang,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2014, 5, 2036–2047, doi:10.3762/bjnano.5.212

• NP surfaces. For both planar and NP surfaces, still more knowledge about the detailed physicochemical processes at the molecular level would be highly desirable. In our view, studying protein–surface interactions by using NPs rather than planar surfaces has significant technical advantages, provided

Dynamic calibration of higher eigenmode parameters of a cantilever in atomic force microscopy by using tip–surface interactions

• Stanislav S. Borysov,
• Daniel Forchheimer and
• David B. Haviland

Beilstein J. Nanotechnol. 2014, 5, 1899–1904, doi:10.3762/bjnano.5.200

• , an enhanced force sensitivity is achieved due to multiplication by the sharply peaked cantilever transfer function. Measurement of response at multiple eigenmodes can provide additional information about the tip–surface interactions [4][5][6][7][8][9][10][11]. The optical detection system [12] common

Real-time monitoring of calcium carbonate and cationic peptide deposition on carboxylate-SAM using a microfluidic SAW biosensor

• Anna Pohl and
• Ingrid M. Weiss

Beilstein J. Nanotechnol. 2014, 5, 1823–1835, doi:10.3762/bjnano.5.193

• the interaction of calcium carbonate with standard carboxylate self-assembled monolayer sensor chips. Different fluids, with and without biomolecular components, were investigated. The pH-dependent surface interactions of two bio-inspired cationic peptides, AS8 and ES9, which are similar to an

• carbonate surface interactions seem to be less well controlled at flow rates higher than 50 µL/min. One can assume that, at higher flow rates, the interaction of calcium and/or (bi)carbonate does not reach the maximum capacity of the sensor surface. Calcium carbonate and citric acid interactions In order to

Single-asperity contact mechanics with positive and negative work of adhesion: Influence of finite-range interactions and a continuum description for the squeeze-out of wetting fluids

• Martin H. Müser

Beilstein J. Nanotechnol. 2014, 5, 419–437, doi:10.3762/bjnano.5.50

• , I want to investigate to what degree such an inversion is possible by studying the sensitivity of the functions d(FN) and ac(FN) to the functional form of the surface interactions. Figure 11 shows the contact radius as a function of the normal load. One can see that the exponential model and the MD

• coefficients. Figure 12 reveals that it is possible to adjust the free parameters of the MD model to fit d(FN) curves for a broad variety of surface interactions. However, one should abstain from deducing contact areas based on such fits, as this can result in non-negligible errors. For example, if we only

• for μT = 1. This is demonstrated in Figure 18. It reveals that information on the (effective) near-range surface interactions at small separation are difficult to obtain from experimentally measured load-displacement curves. I conclude this section with an analysis of the gap profile for repulsive

Photoactivation of luminescence in CdS nanocrystals

• Valentyn Smyntyna,
• Bogdan Semenenko,
• Valentyna Skobeeva and
• Nikolay Malushin

Beilstein J. Nanotechnol. 2014, 5, 355–359, doi:10.3762/bjnano.5.40

• fluorescence enhancement (PFE) [1][2][3][4][5], intermittency or blinking of photoluminescence [6][7][8], and a blue- or red-shift of the exciton PL of nanocrystals [5][9]. Despite the large number of works devoted to the surface interactions in II–IV QDs [2][3][4][5][10] the mechanisms responsible for the

The role of surface corrugation and tip oscillation in single-molecule manipulation with a non-contact atomic force microscope

• Christian Wagner,
• Norman Fournier,
• F. Stefan Tautz and
• Ruslan Temirov

Beilstein J. Nanotechnol. 2014, 5, 202–209, doi:10.3762/bjnano.5.22

• rapid development of scanning probe microscopy (SPM) techniques, investigations of adsorbate–surface interactions on a single-molecule level have become possible [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]. Especially interesting is the possibility of probing the molecule–surface

• carboxylic oxygen atoms. The interaction potentials of the carboxylic oxygen and the backbone atoms are described via two separate parameter sets that amount to a total of five free parameters (if additional chemical molecule–surface interactions are absent). These five parameters, which describe the

Structural development and energy dissipation in simulated silicon apices

• Samuel Paul Jarvis,
• Lev Kantorovich and
• Philip Moriarty

Beilstein J. Nanotechnol. 2013, 4, 941–948, doi:10.3762/bjnano.4.106

• single rotational degree of freedom, the difference in tip–surface interactions can be as significant as for a completely different tip structure. Simulation details Our investigation is performed with ab initio density functional theory (DFT) simulations carried out by using the SIESTA code [41], which

Influence of the solvent on the stability of bis(terpyridine) structures on graphite

• Daniela Künzel and
• Axel Groß

Beilstein J. Nanotechnol. 2013, 4, 269–277, doi:10.3762/bjnano.4.29

• properties of water quite satisfactorily [19][20]. However, here we need general-purpose force fields that are able to describe different solvents, solvent–molecule and molecule–surface interactions equally well. Hence, we use the Universal (UFF) [21], Compass (condensed-phase optimized molecular potentials

Mapping mechanical properties of organic thin films by force-modulation microscopy in aqueous media

• Jianming Zhang,
• Zehra Parlak,
• Carleen M. Bowers,
• Terrence Oas and
• Stefan Zauscher

Beilstein J. Nanotechnol. 2012, 3, 464–474, doi:10.3762/bjnano.3.53

• below the free resonance frequency, and the actuation amplitude is selected to yield a small cantilever amplitude in contact. Furthermore, as shown in Figure 2, AFM tip–surface interactions should be kept in regime D to obtain a linear contact response. This demand needs to be balanced by the need for

Models of the interaction of metal tips with insulating surfaces

• Thomas Trevethan,
• Matthew Watkins and
• Alexander L. Shluger

Beilstein J. Nanotechnol. 2012, 3, 329–335, doi:10.3762/bjnano.3.37

• . Keywords: atomic force microscopy; density functional theory; ionic surfaces; metallic asperities; surface interactions; Introduction The noncontact atomic force microscope (NC-AFM) is capable of imaging both conducting and insulating systems with true atomic resolution and has provided extraordinary

Modeling noncontact atomic force microscopy resolution on corrugated surfaces

• Kristen M. Burson,
• Mahito Yamamoto and
• William G. Cullen

Beilstein J. Nanotechnol. 2012, 3, 230–237, doi:10.3762/bjnano.3.26

• modeling of tip–surface interactions for the case of a corrugated surface. We discuss the issues that arise when the surface is corrugated on relatively small length scales (our best measurements on SiO2 yield a correlation length of 8–10 nm). We develop a continuum model that explicitly accounts for a

Self-assembly of octadecyltrichlorosilane: Surface structures formed using different protocols of particle lithography

• ChaMarra K. Saner,
• Kathie L. Lusker,
• Zorabel M. LeJeune,
• Wilson K. Serem and
• Jayne C. Garno

Beilstein J. Nanotechnol. 2012, 3, 114–122, doi:10.3762/bjnano.3.12

• images indicate differences in tip–surface interactions, but were not normalized for the comparison of friction changes between different tips or experiments. The tips were silicon nitride probes. Tips used with tapping-mode AFM were rectangular shaped ultrasharp silicon tips that have an aluminium

Fabrication of multi-parametric platforms based on nanocone arrays for determination of cellular response

• Lindarti Purwaningsih,
• Tobias Schoen,
• Tobias Wolfram,
• Claudia Pacholski and
• Joachim P. Spatz

Beilstein J. Nanotechnol. 2011, 2, 545–551, doi:10.3762/bjnano.2.58

• grooves, ridges and wells, the research focus has shifted to the investigation of the potential of nanostructured materials for controlling cell–surface interactions [8]. For several years experimental studies on the influence of nanoscale topography on cell behavior have been largely obstructed by the

• study cell–surface interactions through topographical and chemical gradients have been reported to date [18]. Representative review articles on neuronal cell response to nanostructured surfaces have been published [19][20]. Despite the enormous effort made in this research area, intelligently designed

Manipulation of gold colloidal nanoparticles with atomic force microscopy in dynamic mode: influence of particle–substrate chemistry and morphology, and of operating conditions

• Samer Darwich,
• Karine Mougin,
• Akshata Rao,
• Enrico Gnecco,
• Shrisudersan Jayaraman and
• Hamidou Haidara

Beilstein J. Nanotechnol. 2011, 2, 85–98, doi:10.3762/bjnano.2.10

• nanoparticles during their manipulation using AFM in tapping mode has been investigated. In particular, the effects of the size, shape and coating of the nanoparticles, the lateral scan velocity, the particle-surface interactions and the environmental conditions, especially temperature T and relative humidity

• the particle (chemistry, size, shape) and the substrate (chemistry and topography) have been investigated. It has been shown that the mobility of the particles was significantly affected by the nature of intermolecular tip–particle and particle–surface interactions, the particle shape and size, the