Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• drugs from clearance, improve their accumulation at tumor sites, and potentially lead to more positive clinical feedback. Paclitaxel (PTX) was approved by the FDA in 1992 for the treatment of a variety of solid tumors. Poor water solubility is a major obstacle limiting its anticancer activity. PTX

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease

• Niédja Fittipaldi Vasconcelos,
• Almerinda Agrelli,
• Rayane Cristine Santos da Silva,
• Carina Lucena Mendes-Marques,
• Isabel Renata de Souza Arruda,
• Priscilla Stela Santana de Oliveira,
• Mércia Liane de Oliveira and
• Giovanna Machado

Beilstein J. Nanotechnol. 2025, 16, 1711–1733, doi:10.3762/bjnano.16.120

• components. When NE is instilled, the oil nanodroplets merge with the lipid layer, the water in the formulation interacts with the aqueous layer of the tear film, and the surfactant interacts with the mucin layer [21][22][23]. The literature cites various lipids as components of the oily phase in

• analytical grade reagents were used as received from the supplier without further purification. Ultrapure water was obtained from a Milli-Q® (Merck Millipore) direct water purification system (18.2 MΩ·cm) and used for all aqueous solutions. L-929 cells (code 0188) were obtained from the Banco de Células do

• (25 mL) were prepared by varying the egg lecithin concentration from 1% to 5% (w/w) in 8% (w/w) oil in water, resulting in pre-emulsions with five distinct concentrations (described in Table S1, Supporting Information File 1). The oil and aqueous phases were heated separately to 75 °C. The mass of egg

Beyond the bilayer: multilayered hygroscopic actuation in pine cone scales

• Kim Ulrich,
• Max David Mylo,
• Tom Masselter,
• Fabian Scheckenbach,
• Sophia Fischerbauer,
• Martin Nopens,
• Silja Flenner,
• Imke Greving,
• Linnea Hesse and
• Thomas Speck

Beilstein J. Nanotechnol. 2025, 16, 1695–1710, doi:10.3762/bjnano.16.119

• investigated. Using gravimetric water uptake measurements, synchrotron radiation-based nano-holotomography, and digital volume correlation analysis, inter- and intra-tissue variations of hygroscopic swelling/shrinkage were observed. In addition, the moisture content of pine cone scale tissues was measured as a

• the bending motion of the scale. One crucial influencing factor is the difference within or between tissues, as Eger et al. [23] highlighted. The authors measured the relative change of moisture content as a function of relative humidity by gravimetric water uptake measurements of the sclereid cells

• , the brown tissue, and the sclerenchyma fibers of a Pinus wallichiana pine cone scale. However, as their water uptake measurements consisted of only one measurement per tissue, being limited to the range of 30–80% RH, and their equilibrium criterion being one hour of exposure instead of a mass change

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• Physics of the University of Trieste [22], and supported by DFT, the authors demonstrated that the Co-porphyrin SAC stabilizes a hydroperoxyl–water (O2H-H2O) cluster in O2+H2O atmosphere at room temperature [21]. This is considered the fundamental reaction intermediate in the ORR. In particular, the

• important challenges for modern human civilization. Reactions such as water splitting, CO2 reduction, and pollutant degradation rely on photocatalysts that absorb light, generate electron–hole pairs, and drive redox reactions at interfaces. For the rational and methodical design of a more sophisticated

• application is photocatalytic water splitting for green hydrogen production. Urpelainen and colleagues clarified the mechanisms of photocatalytic hydrogen evolution reaction (HER) in a new prospective model system, the Ni@NiO/NiCO3 photocatalyst, under dark and illuminated conditions at 1 mbar of H2O [45

Prospects of nanotechnology and natural products for cancer and immunotherapy

• Jan Filipe Andrade Santos,
• Marcela Bernardes Brasileiro,
• Pamela Danielle Cavalcante Barreto,
• Ligiane Aranha Rocha and
• José Adão Carvalho Nascimento Júnior

Beilstein J. Nanotechnol. 2025, 16, 1644–1667, doi:10.3762/bjnano.16.116

• aptamer, sorafenib, and ursolic acid as an API at 4 mg·mL−1 in methanol. Physicochemical tests showed that the nanoparticles have a spherical shape, confirmed by atomic force microscopy (AFM), and are stable in ultrapure water and Dulbecco’s modified eagle medium (DMEM) with 10% FBS. Procedures to

Venom-loaded cationic-functionalized poly(lactic acid) nanoparticles for serum production against Tityus serrulatus scorpion

• Philippe de Castro Mesquita,
• Karla Samara Rocha Soares,
• Manoela Torres-Rêgo,
• Emanuell dos Santos-Silva,
• Mariana Farias Alves-Silva,
• Alianda Maira Cornélio,
• Matheus de Freitas Fernandes-Pedrosa and
• Arnóbio Antônio da Silva-Júnior

Beilstein J. Nanotechnol. 2025, 16, 1633–1643, doi:10.3762/bjnano.16.115

• Louis, Missouri, United States of America). The BCA Protein Assay Kit was purchased from Pierce Biotechnology (Woburn, Massachusetts, United States of America) and mouse IgG total ELISA was purchased from eBioscience (San Diego, California, United States of America). Purified water (1.3 µS·cm−1) was

• , United States of America), equipped with a 90 Plus/BI-MAS apparatus, at a wavelength of 659 nm with a scattering angle of 90°. For the analysis, 100 μL of the nanoparticle suspension was diluted in 900 μL of deionized water (1:10 dilution) to ensure dispersions within a suitable experimental range (100

• weeks old), from both sexes were used for the studies. The animals were maintained at 22 ± 2 °C and in a 12 h dark/12 h light cycle, with free access to standard laboratory chow and water. Each experimental group was composed of five animals (n = 5). After the experiments, all animals were euthanized

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• , and advanced membrane materials, exhibit unique properties such as high surface area, enhanced reactivity, and tunable surface chemistry, which offer promising avenues for the selective and efficient removal of MPs from water. This paper also explores the mechanism, performance and limitations of

• for MP monitoring. Despite high laboratory scale efficiencies, there are several challenges such as material scalability, environmental safety, regulatory frameworks, and real water applicability. This study proposes future directions for sustainable nanotechnology deployment, including green

• wear, and microbial activity [3]. Common types of MPs found in ecosystems, particularly in freshwater and drinking water sources, include materials such as high-density polyethylene, polystyrene, polyvinyl chloride, and polypropylene [4]. Among the various contributors to MPs, residential households

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

• systems with different mechanical properties. As a hemiparasite, it uses a modified organ called the “haustorium” with wedge-shaped, or simplified, V-shaped structures to penetrate the host and establish a physiological and mechanical connection (Figure 1) [26][27][28]. This allows it to take up water and

Photocatalytic degradation of ofloxacin in water assisted by TiO₂ nanowires on carbon cloth: contributions of H₂O₂ addition and substrate absorbability

• Iram Hussain,
• Lisha Zhang,
• Zhizhen Ye and
• Jin-Ming Wu

Beilstein J. Nanotechnol. 2025, 16, 1567–1579, doi:10.3762/bjnano.16.111

• unsatisfactory interaction with target contaminants diminishes photocatalytic degradation efficiency in water. Here, we present a mild solution method to precipitate anatase TiO2 nanowire arrays, measuring 1.5 μm in thickness, over carbon cloth to ensure substantial interactions with target pollutants and, in

• turn, a superior photoactivity. Compared to TiO2 nanowire arrays grown on metallic Ti substrates, TiO2 nanowires supported on carbon cloth substrates demonstrate markedly superior efficiency in the photocatalytic degradation of ofloxacin (OFL) molecules in water when exposed to UV light. The TiO2

• nanowires remove 90–97% OFL in water with a high initial concentration of 50 ppm in 6 h under UV light irradiation for up to six cycles. The contributions of the hydrogen peroxide (H2O2) additive were also studied. An enhanced efficiency could be achieved only when the H2O2 in water reaches a critical

Transient electronics for sustainability: Emerging technologies and future directions

• Jae-Young Bae,
• Myung-Kyun Choi and
• Seung-Kyun Kang

Beilstein J. Nanotechnol. 2025, 16, 1545–1556, doi:10.3762/bjnano.16.109

• environments, these devices maintain their ability to decompose through interactions with naturally occurring water and enzymes (Figure 1f) [32]. Thus, transient electronics present a compelling vision for sustainable electronics, that is, devices that fulfill their intended function and then seamlessly

• circuits, such as ring oscillators, entirely composed of water-soluble materials, supporting its applicability in future bioelectronic devices. Nevertheless, the currently known repertoire of bioresorbable semiconductors remains narrow, both in material selection and bandgap range. Expanding the library to

• protective encapsulation [37][40][82][83][84]. These encapsulation layers delay the exposure of active electronic materials to moisture, enabling precise control over operational lifetime and ensuring stable performance over the desired period. However, these materials need to simultaneously block water

Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• laser pulses. For example, laser beams with a donut shape were used for ablating gold, yttrium oxide, and high-entropy alloy targets in water. The donut beam enabled NP size reduction and narrower size distributions [28]. Application of femtosecond Bessel beams for the ablation of silver in a liquid was

• reports on non-spherical nanostructures synthesized using different beam shapes is a work by Marappu et al [30], where a cylindrical focusing geometry was demonstrated to result in the fabrication of silver nanoribbons via picosecond laser ablation of bulk silver in doubly distilled water. Therefore

Dendrimer-modified carbon nanotubes for the removal and recovery of heavy metal ions from water

• Thao Quynh Ngan Tran,
• Huu Trung Nguyen,
• Subodh Kumar and
• Xuan Thang Cao

Beilstein J. Nanotechnol. 2025, 16, 1522–1532, doi:10.3762/bjnano.16.107

• of water bodies with heavy metal ions poses a significant threat to the environment and human health due to their non-degradable nature and toxicity. Metal-oriented industries such as battery manufacturing, mining, electroplating, and metal recycling are growing day by day, and so are the chances of

• metals from water solution [28][29][30]. However, the poor dispersibility of bare CNTs in most solvents including water is a significant limitation to their wider applicability. Covalent modification of CNT surfaces with dendrimers of desirable functionality can improve their dispersibility and binding

• and 150 °C for the unfunctionalized CNTs, which is attributed to the release of physically adsorbed water. Moreover, bare CNTs exhibited thermal stability up to 800 °C with a residual weight of 97.80% suggesting the absence of organic functional groups. In contrast, CNTs functionalized with MA and EDA

Nanomaterials for biomedical applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Filippo Pierini,
• Seda Kizilel and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 1499–1503, doi:10.3762/bjnano.16.105

• membranes [8]. They can carry both water-soluble and fat-soluble drugs, shielding them from breaking down and extending their circulation time. Certain liposome-based drugs have already been approved for therapeutic use, especially in cancer therapy, where they may protect nearby healthy cells from toxicity

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• , electrochemical/photoelectrochemical sensors, hydrogen/oxygen evolution, SERS sensors and other types of devices reported so far. The last section explains the challenges and further scope of these devices from laser-generated nanocolloids. Keywords: HER/OER/water splitting; laser synthesis of nanomaterials

• pulsed laser fragmentation of PbTe micrometer-sized powders in distilled water using a Nd:YAG laser [31]. The study examined the impact of various experimental parameters, including laser wavelength (Figure 3a), treatment duration, and output energy, on the fragmentation yield, nanoparticle size, and

• water successfully alters the surface properties of Si-ncs, making them hydrophilic and improving their dispersion in aqueous solutions, while also leading to the formation of self-organized networks. However, laser fragmentation of BaTaOxNy particles resulted not only in increased surface area but also

Photochemical synthesis of silver nanoprisms via green LED irradiation and evaluation of SERS activity

• Tuan Anh Mai-Ngoc,
• Nhi Kieu Vo,
• Cong Danh Nguyen,
• Thi Kim Xuan Nguyen and
• Thanh Sinh Do

Beilstein J. Nanotechnol. 2025, 16, 1417–1427, doi:10.3762/bjnano.16.103

• . Polyvinylpyrrolidone (PVP K30) were purchased from Prolabo, Kennersburg, NJ, USA. Chemicals were used without any purification. Deionized (DI) water with a resistance of 18 MΩ·cm (Milli-Q) was used in all the experiments. All glasswares were cleaned with aqua regia before use. Synthesis of seeds A total of 10 mL of

• 0.05 M trisodium citrate (TSC), 300 µL of 0.05 M polyvinylpyrrolidone (PVP), 20 mL of 5 mM AgNO3, and 500 µL of 0.005 M ʟ-arginine solution were added into a beaker. Deionized water was then added to adjust the total volume of the solution to 100 mL. The mixture was magnetically stirred at 500 rpm for

• nm. Samples were diluted tenfold with deionized water prior to measurement. To determine the morphology, particle size of the synthesized nanostructures, the samples were analyzed using field-emission scanning electron microscopy (FESEM, Hitachi S-4800, Japan) and transmission electron microscopy

The role of biochar in combating microplastic pollution: a bibliometric analysis in environmental contexts

• Tuan Minh Truong Dang,
• Thao Thu Thi Huynh,
• Guo-Ping Chang-Chien and
• Ha Manh Bui

Beilstein J. Nanotechnol. 2025, 16, 1401–1416, doi:10.3762/bjnano.16.102

• , Ho Chi Minh City 700000, Vietnam 10.3762/bjnano.16.102 Abstract This study employs a bibliometric analysis using CiteSpace to explore research trends on the impact of biochar on microplastics (MPs) in soil and water environments. In agricultural soils, MPs reduce crop yield, alter soil properties

• sources in the environment and biota. Although MPs are produced in large quantities, effective removal techniques remain underdeveloped [5][6]. Recent studies have confirmed the widespread presence of MPs in agricultural soils and water bodies, highlighting their environmental and human health risks. In

• Indore City, India [9]. MP contamination extends to water bodies, where seasonal variations influence the distribution of MPs. In South African rivers such as Crocodile and Luvuvhu, MP concentrations in water were higher during the dry season (5.4 particles/L) than in the wet season (3.3–4.3 particles/L

Parylene-coated platinum nanowire electrodes for biomolecular sensing applications

• Chao Liu,
• Peker Milas,
• Michael G. Spencer and
• Birol Ozturk

Beilstein J. Nanotechnol. 2025, 16, 1392–1400, doi:10.3762/bjnano.16.101

• structures [18][19][20][21]. These characteristics allow DENA to create a variety of structures for nanoscale biosensor manufacturing. Parylene-C is a polymer known for its exceptional properties, including high tensile strength, excellent electrical insulation, low water permeability, and biocompatibility

• water as a catalyst, then the final product gluconolactone was generated [28][29]. These reactions were illustrated in Scheme 2. Similarly, peaks were observed to be same during the reverse scan [29]. Based on curve shape and reaction mechanism, the peaks from the reverse curve around 50 mV were

• dopamine testing experiments, and all solutions were prepared with 18 MΩ·cm deionized water. A Gamry 1000E potentiostat was used for DPV tests, where the scan range was from −0.2 to 0.7 V, the step value was 2.0 mV, the sample period was 0.5 s, the pulse time was 0.05 s, and the pulse size was 25 mV. To

Synthesis and antibacterial properties of nanosilver-modified cellulose triacetate membranes for seawater desalination

• Lei Wang,
• Shizhe Li,
• Kexin Xu,
• Wenjun Li,
• Ying Li and
• Gang Liu

Beilstein J. Nanotechnol. 2025, 16, 1380–1391, doi:10.3762/bjnano.16.100

• properties. Antibacterial ring experiments revealed significant bactericidal activity against five different bacterial strains, namely, Bacillus cereus, Bacillus thuringiensis, Lysinibacillus xylanilyticus, Lysinibacillus lparviboronicapiens and Burkholderia ambifaria. Moreover, water flux and salt rejection

• . Concurrently, the consumption of freshwater in industrial and agricultural sectors is also witnessing a significant increase [1][2]. On Earth, while oceans cover approximately 75% of the surface, freshwater constitutes merely 2.5% of the total water volume [3][4][5]. Moreover, 70% of these freshwater resources

• are located in glaciers, the atmosphere, and soil; rendering them difficult to access and utilize [5][6][7]. To tackle the challenge of clean water scarcity, desalination of seawater or brackish water have emerged as effective solutions [1][8][9]. According to the literature, desalination technologies

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• enabling controlled release and selective accumulation at the infection site, as well as facilitating the delivery of antibiotics to intracellular bacterial reservoirs [54][55]. Altogether, these advantages contribute to enhanced therapeutic efficacy, improved solubility of poorly water-soluble compounds

• interface or within imperfections of the solid core [74]. Despite their advantages, SLNs face certain challenges, such as limited drug loading capacity due to the crystalline structure of the solid lipid matrix, risks of drug leakage during storage, and a relatively high water content in the formulation [73

• presence of polar silanol groups, which enhance stability and the ability to absorb water. These properties make them excellent carriers for bioactive molecules, providing efficient encapsulation and controlled release. SiNPs can be engineered to release their payloads in response to specific stimuli

Deep-learning recognition and tracking of individual nanotubes in low-contrast microscopy videos

• Vladimir Pimonov,
• Said Tahir and
• Vincent Jourdain

Beilstein J. Nanotechnol. 2025, 16, 1316–1324, doi:10.3762/bjnano.16.96

• and carrier gas. Oxygen and water sensors monitored gas-phase contaminants at the outlet line. In situ microscopy Nanotube growth was imaged in situ using a custom-built optical setup for homodyne polarization microscopy. A supercontinuum source (Fianium SC-400-4, 2 ps pulses, 40 MHz, spectral range

Wavelength-dependent correlation of LIPSS periodicity and laser penetration depth in stainless steel

• Nitin Chaudhary,
• Chavan Akash Naik,
• Shilpa Mangalassery,
• Jai Prakash Gautam and
• Sri Ram Gopal Naraharisetty

Beilstein J. Nanotechnol. 2025, 16, 1302–1315, doi:10.3762/bjnano.16.95

• grades of emery paper (3000, 4000, and 5000). Subsequently, alumina polishing was applied for 20 min to achieve a flawless mirror finish on the surface. A solution containing 10 g of oxalic acid in 100 mL of distilled water was employed for etching the stainless steel. An external etching process was

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• samples fabricated with lower current density, highlighting the benefits of the optimized electrodeposition conditions for the former. Keywords: BiOI; BiVO4; electrodeposition; photoelectrochemical water splitting; Introduction In the context of the increasing global energy demand, the development of

• renewable and sustainable energy sources has become a top priority in science and technology [1][2]. Photoelectrochemical (PEC) water-splitting systems hold significant promises for converting abundant solar energy into chemical fuels, such as hydrogen [3][4]. However, their widespread application is still

• -guided route for improving water oxidation performance. However, the use of a constant-potential deposition technique presents limitations in controlling the film thickness, morphology, and uniformity, which are crucial for consistent BiVO4 performance after conversion. Variability in the BiOI film

Acrocomia aculeata oil-loaded nanoemulsion: development, anti-inflammatory properties, and cytotoxicity evaluation

• Verónica Bautista-Robles,
• Hady Keita,
• Edgar Julián Paredes Gamero,
• Layna Tayná Brito Leite,
• Jessica de Araújo Isaías Muller,
• Mônica Cristina Toffoli Kadri,
• Ariadna Lafourcade Prada and
• Jesús Rafael Rodríguez Amado

Beilstein J. Nanotechnol. 2025, 16, 1277–1288, doi:10.3762/bjnano.16.93

• , nutraceutical, and industrial applications. However, due to the chemical and physicochemical characteristics as well as the solubility and stability of this oil, it was decided to make a nanoemulsion to enhance its already known therapeutic benefits. Nanoemulsions are nanoemulsified systems, either oil-in-water

• (O/W) or water-in-oil (W/O), which are isotropic, homogeneous, and thermodynamically unstable, with droplet sizes ranging from 20 to 200 nm [20]. They present properties such as high surface area per unit volume, robust kinetic stability, and tunable rheology [21]. It has been demonstrated that

• emulsified systems loaded with plant extracts have better pharmacological activity than extracts when used naturally [22]. For example, plant oil-loaded nanoemulsions exhibit high water solubility, improved permeability, and enhanced bioavailability [23]. This contrasts with the limited solubility and poor

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• exposed to a hypotonic solution, water enters the erythrocytes, an equilibrium is established as substances enter and leave the swollen RBCs. A hypotonic solution is prepared by dissolving a relatively higher amount of the drug. Drug loading can be enhanced by carrying out the process at 0 °C as the fatty

Functional bio-packaging enhanced with nanocellulose from rice straw and cinnamon essential oil Pickering emulsion for fruit preservation

• Tuyen B. Ly,
• Duong D. T. Nguyen,
• Hieu D. Nguyen,
• Yen T. H. Nguyen,
• Bup T. A. Bui,
• Kien A. Le and
• Phung K. Le

Beilstein J. Nanotechnol. 2025, 16, 1234–1245, doi:10.3762/bjnano.16.91

• exhibits good heat-resistance, mechanical, and water-barrier properties. At an emulsion concentration as low as 10% (v/w) in the casting solution, high UV absorbance capacity (up to 100% UVC), high antibacterial activity (92.4% Escherichia coli inhibition), and good antioxidative properties (up to 43% DPPH

• biodegradability [1][2][3]. Polyvinyl alcohol (PVA) has been shown to provide better biodegradability compared to other polymers such as polyethylene, polyvinyl chloride, and polystyrene [4][5][6] due to its secondary alcohol groups being susceptible to enzymatic oxidation and its water solubility enhancing

• degradation byproducts [8][9]. One problem is that the hydrophilic structure of PVA gives it a high water-solubility, water uptake, and worse mechanical properties [10][11]. Different filler and nanomaterials including silica [12][13][14], graphene [15][16], and metals [17][18] have been added to PVA to