Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with Escherichia coli cells

• Eloïse Equy,
• Jordana Hirtzel,
• Sophie Hellé,
• Béatrice Heurtault,
• Eric Mathieu,
• Morgane Rabineau,
• Vincent Ball and
• Lydie Ploux

Beilstein J. Nanotechnol. 2023, 14, 1208–1224, doi:10.3762/bjnano.14.100

• , France UMR 7199, CNRS/University of Strasbourg, 74 route du Rhin, 67401 Illkirch, France CNRS, 23 rue du Loess, 67200 Strasbourg, France 10.3762/bjnano.14.100 Abstract Inspired by the eumelanin aggregates in human skin, polydopamine nanoparticles (PDA NPs) are promising nanovectors for biomedical

• bacteria. Inspired by the eumelanin aggregates in human skin, polydopamine nanoaggregates (here referred to as nanoparticles, i.e., PDA NPs) have emerged as promising nanovectors for biomedical applications [11][12], especially because of their biocompatibility [13][14] and photothermic properties [15][16

Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment

• Lester Uy Vinzons,
• Guo-Chung Dong and
• Shu-Ping Lin

Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96

• Lester Uy Vinzons Guo-Chung Dong Shu-Ping Lin Doctoral Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung City 40227, Taiwan (R.O.C.) Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli County 35053

• , Taiwan (R.O.C.) Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung City 40227, Taiwan (R.O.C.) 10.3762/bjnano.14.96 Abstract Surface micro- and nanostructures profoundly affect the functional performance of nerve regeneration implants by modulating neurite responses

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

• Nittiya Suwannasom,
• Netsai Sriaksorn,
• Chutamas Thepmalee,
• Krissana Khoothiam,
• Ausanai Prapan,
• Hans Bäumler and
• Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

• addition, the removal of sericin, which requires a degumming process, is a prerequisite for using silk cocoons in biomedical applications to reduce the risk of an inflammatory response [18]. However, this degumming process can lead to damage to the silk structure, increase the polydispersity of the silk

Spatial mapping of photovoltage and light-induced displacement of on-chip coupled piezo/photodiodes by Kelvin probe force microscopy under modulated illumination

• Zeinab Eftekhari,
• Nasim Rezaei,
• Hidde Stokkel,
• Jian-Yao Zheng,
• Andrea Cerreta,
• Ilka Hermes,
• Minh Nguyen,
• Guus Rijnders and
• Rebecca Saive

Beilstein J. Nanotechnol. 2023, 14, 1059–1067, doi:10.3762/bjnano.14.87

• precise motion with high resolution. This offers promising possibilities for biomedical, environmental, and micro/nanoengineering applications [5][6]. Various types of design and actuation mechanisms have been developed in recent years [7][8]. A primary requirement to unlock the better performance of

A visible-light photodetector based on heterojunctions between CuO nanoparticles and ZnO nanorods

• Doan Nhat Giang,
• Nhat Minh Nguyen,
• Duc Anh Ngo,
• Thanh Trang Tran,
• Le Thai Duy,
• Cong Khanh Tran,
• Thi Thanh Van Tran,
• Phan Phuong Ha La and
• Vinh Quang Dang

Beilstein J. Nanotechnol. 2023, 14, 1018–1027, doi:10.3762/bjnano.14.84

• photodetectors (PDs) to “Industry 4.0”, which may include image sensors, biomedical imaging, manufacturing process control, environmental sensing, and optical sensors [8]. Various materials for photodetectors have been developed. Photodetectors can be classified into two main categories, namely PDs that work at

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• Elangovan Sarathkumar Rajasekharan S. Anjana Ramapurath S. Jayasree Division of Biophotonics and Imaging, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojappura, Thiruvananthapuram-695012, Kerala, India 10.3762/bjnano.14.82 Abstract Lateral flow

• to control the nanoscale architecture makes them a great choice for biomedical applications [49][50]. Gold nanostructures such as spheres, rods, stars, shells, and cages are often used as photothermal agents [51][52]. The surface plasmon resonance frequency of gold nanomaterials can be easily

Ni, Co, Zn, and Cu metal-organic framework-based nanomaterials for electrochemical reduction of CO₂: A review

• Ha Huu Do and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 904–911, doi:10.3762/bjnano.14.74

• [28][29][30], and biomedical [31] applications. These materials are distinguished by their exceptional attributes, including a substantial specific surface area, pronounced porosity, and modifiable chemical structures [32]. Within the catalytic domain, MOFs demonstrate catalytic activity stemming from

Biomimetics on the micro- and nanoscale – The 25th anniversary of the lotus effect

• Matthias Mail,
• Kerstin Koch,
• Thomas Speck,
• William M. Megill and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2023, 14, 850–856, doi:10.3762/bjnano.14.69

• paper “Bioselectivity of silk protein-based materials and their bio-inspired applications” the importance of tailoring bioselective, biologically active, and multifunctional materials for biomedical applications in biomaterial research. The review was focused on two major topics, the first one being

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• ; environmentally mediated dissolution; nanoceria; Introduction Background Ceria nanomaterials have many applications, including acting as redox catalysts/metal supports [1], sunscreens [2], heat-resistant coatings [3], and much more [4]. Biomedical applications of ceria-based compounds as therapeutics have the

Nanoarchitectonics for advanced applications in energy, environment and biology: Method for everything in materials science

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2023, 14, 738–740, doi:10.3762/bjnano.14.60

• ], but also from applied fields such as catalysis [20][21], sensors [22][23], devices [24][25], environmental research [26][27], energy [28][29], and biomedical [30][31] fields. In this thematic issue entitled “Nanoarchitectonics for advanced applications in energy, environment and biology”, the authors

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

Microneedle patches – the future of drug delivery and vaccination?

• Zahra Faraji Rad,
• Philip D. Prewett and
• Graham J. Davies

Beilstein J. Nanotechnol. 2023, 14, 494–495, doi:10.3762/bjnano.14.40

• applications [2]. Recent research has also revealed a growing interest in diagnostic testing using the interstitial fluid (ISF) transdermally extracted, for example using suction devices [3], and there is increasing recognition by doctors and biomedical scientists of the potential role of the ISF in medical

• availability of regulatory-approved MN patches for a wide range of clinical and biomedical applications. We are grateful to the authors for their excellent contributions to this thematic issue; we are very aware of the demands on their time. We also thank the Beilstein-Institut editorial team for their highly

A mid-infrared focusing grating coupler with a single circular arc element based on germanium on silicon

• Xiaojun Zhu,
• Shuai Li,
• Ang Sun,
• Yongquan Pan,
• Wen Liu,
• Yue Wu,
• Guoan Zhang and
• Yuechun Shi

Beilstein J. Nanotechnol. 2023, 14, 478–484, doi:10.3762/bjnano.14.38

• resonance platform will further contribute to the field of biomedical sensors. We also studied the sensing performance of our proposed MIR FGC when it worked as a sensor rather than a coupler, as shown in Figure 6. When RI increases from 1 to 1.04, the peak of coupling efficiency shows a redshift from

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

• tunability of optothermal properties and enhanced stability, these nanostructures show a wide range of applications in optical sensors, steam generation, water desalination, thermal energy storage, and biomedical applications such as photothermal (PT) therapy. The PT effect, that is, the conversion of

Polymer nanoparticles from low-energy nanoemulsions for biomedical applications

• Santiago Grijalvo and
• Carlos Rodriguez-Abreu

Beilstein J. Nanotechnol. 2023, 14, 339–350, doi:10.3762/bjnano.14.29

• , particularly by the phase inversion composition method, and the use of these nanoemulsions as templates for the preparation of polymer nanoparticles for biomedical applications are reviewed. The methods of preparation, nature of the components in the formulation, and their impact on the physicochemical

• research on the fabrication of polymer nanoparticles from low-energy nanoemulsions, focusing on phase inversion composition. We particularly emphasize their biomedical applications as drug carriers. 2 Nanoemulsions Nanoemulsions are constituted by nanoscale droplets (20–200 nm) dispersed in a continuous

• surfactant/water/oil systems through the use of phase diagrams is usually needed. For biomedical applications, this is further complicated by the fact that the list of available components is restricted by regulations. The most straightforward strategy to obtain polymer nanoparticles from nanoemulsions is to

Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles

• Magdalena Lasak and
• Karol Ciepluch

Beilstein J. Nanotechnol. 2023, 14, 329–338, doi:10.3762/bjnano.14.28

• form one of the most selective permeability barriers [33] (Figure 4). Studies on NanoEL are a valuable source of information with respect to the potential future of biomedical applications. Designing NPs with optimal physicochemical properties could enable predicted and controlled leakiness, thus

• therapeutic effectiveness, regulated pharmacokinetics, known biodistribution, and minimal side effects are being sought. The mechanism of NanoEL shows great potential for future biomedical applications, but a more thorough investigation is still required [5]. Conclusion Effective transport of NPs to the

Biocatalytic synthesis and ordered self-assembly of silica nanoparticles via a silica-binding peptide

• Mustafa Gungormus

Beilstein J. Nanotechnol. 2023, 14, 280–290, doi:10.3762/bjnano.14.25

• Mustafa Gungormus Biomedical Engineering, School of Engineering and Natural Sciences, Ankara Yildirim Beyazit University, Ankara, Türkiye MERLAB Application and Research Center, Ankara Yildirim Beyazit University, Ankara, Türkiye 10.3762/bjnano.14.25 Abstract Achieving scalable and economic

Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

• in real time [84]. Conclusion Biomimetic cancer cell membrane-coated NPs present unique advantages that provide new breakthrough ideas for various obstacles in the field of biomedical treatment. Numerous biomimetic nanoagents based on cancer cell membrane-related functions have been reported and

Concentration-dependent photothermal conversion efficiency of gold nanoparticles under near-infrared laser and broadband irradiation

• Vikas,
• Raj Kumar and
• Sanjeev Soni

Beilstein J. Nanotechnol. 2023, 14, 205–217, doi:10.3762/bjnano.14.20

• Vikas Raj Kumar Sanjeev Soni Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India Biomedical Applications Group, CSIR ­ Central Scientific Instruments Organisation, Sector-30C, Chandigarh-160030, India Micro and Nano Optics Centre, CSIR ­ Central Scientific Instruments

• , and the characteristics of irradiation source [12][13][14][15][16][17]. For biomedical applications, to achieve maximum light penetration, a light source of spectral output within 700–900 nm (NIR-I range, termed therapeutic window) is required [18][19][20]. Here, the photothermal conversion efficiency

Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine

• Zoran M. Marković,
• Milica D. Budimir,
• Martin Danko,
• Dušan D. Milivojević,
• Pavel Kubat,
• Danica Z. Zmejkoski,
• Vladimir B. Pavlović,
• Marija M. Mojsin,
• Milena J. Stevanović and
• Biljana M. Todorović Marković

Beilstein J. Nanotechnol. 2023, 14, 165–174, doi:10.3762/bjnano.14.17

• ][20][21]. Because of the low dark cytotoxicity they can be used successfully for bioimaging of different cells [22][23]. In our previous research, we investigated the effect of various parameters on structural, optical, and biomedical properties of CQDs [5]. We reported how heteroatom dopants

• o-phenylenediamine did not disrupt the cytoplasmic membrane. Cytotoxicity testing Low cytotoxicity is one of the mandatory requirements for biomedical applications. In this paper, we performed cell viability tests by applying the MTT assay toward MRC5 human lung fibroblast cells. Lung fibroblasts

Two-step single-reactor synthesis of oleic acid- or undecylenic acid-stabilized magnetic nanoparticles by thermal decomposition

• Mykhailo Nahorniak,
• Pamela Pasetto,
• Jean-Marc Greneche,
• Volodymyr Samaryk,
• Sandy Auguste,
• Anthony Rousseau,
• Nataliya Nosova and
• Serhii Varvarenko

Beilstein J. Nanotechnol. 2023, 14, 11–22, doi:10.3762/bjnano.14.2

• , wüstite), particularly nanosized particles, show distinct effects on living organisms. Thus, it is of primary importance for their biomedical applications that the morphology and phase-structural state of these materials are investigated. The aim of this work was to obtain magnetic nanoparticles in a

• chemical and physical properties. One such area is biomedicine [1]. Especially iron oxide-based nanoparticles, due to their biodegradation, low toxicity, and enhanced oxidative resistance compared to metallic nanoparticles, show high potential in biomedical applications [2][3][4]. Up to now, iron oxide

• , studying the morphology and phase composition of iron-oxide-based nanoparticles is a critical issue. Nevertheless, magnetite and maghemite particles remain the most commonly used nanoparticles in biomedical applications. However, it must be noted that magnetite nanoparticles undergo rapid oxidation in air

Single-step extraction of small-diameter single-walled carbon nanotubes in the presence of riboflavin

• Polina M. Kalachikova,
• Anastasia E. Goldt,
• Eldar M. Khabushev,
• Timofei V. Eremin,
• Timofei S. Zatsepin,
• Elena D. Obraztsova,
• Konstantin V. Larionov,
• Liubov Yu. Antipina,
• Pavel B. Sorokin and
• Albert G. Nasibulin

Beilstein J. Nanotechnol. 2022, 13, 1564–1571, doi:10.3762/bjnano.13.130

• . Biomedical applications apply an additional constraint on the diameter of nanotubes. Small-diameter SWCNTs display intrinsic photoluminescence in the spectral range of 900–1100 nm within the biological transparency window, making them ideal candidates for single-molecule biosensors or biomedical imaging

• biocompatibility of nucleic acids can support biomedical applications of such dispersions. Unfortunately, an extensive ultrasonic treatment required to obtain a dispersion of individual nanotubes might destroy fragile nucleic acid molecules so that their applications are somewhat inhibited. Flavin compounds are

• -resolution imaging of specific tissues [29]. Notably, single-step extraction of carbon nanotubes in an aqueous media without surfactants or organic additives can significantly shorten the path from industrial or laboratory reactors to in vitro and in vivo biomedical research and further. Conclusion We

Frequency-dependent nanomechanical profiling for medical diagnosis

• Santiago D. Solares and
• Alexander X. Cartagena-Rivera

Beilstein J. Nanotechnol. 2022, 13, 1483–1489, doi:10.3762/bjnano.13.122

• Santiago D. Solares Alexander X. Cartagena-Rivera Department of Mechanical and Aerospace Engineering, The George Washington University, School of Engineering and Applied Science, Washington, District of Columbia, USA Section on Mechanobiology, National Institute of Biomedical Imaging and

Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy

• Yuran Wang,
• Xudong Li,
• Haijun Chen and
• Yu Gao

Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118

• development of Au- and BODIPY-grafted LNPs using a very simple and convenient method. PTT-induced direct anti-tumor effects through photothermal ablation or hyperthermia have been widely studied [28]. AuNPs are one of the most attractive PTAs for biomedical applications because of their biocompatibility and

Laser-processed antiadhesive bionic combs for handling nanofibers inspired by nanostructures on the legs of cribellate spiders

• Sebastian Lifka,
• Kristóf Harsányi,
• Erich Baumgartner,
• Lukas Pichler,
• Dariya Baiko,
• Karsten Wasmuth,
• Johannes Heitz,
• Marco Meyer,
• Anna-Christin Joel,
• Jörn Bonse and
• Werner Baumgartner

Beilstein J. Nanotechnol. 2022, 13, 1268–1283, doi:10.3762/bjnano.13.105

• Sebastian Lifka Kristof Harsanyi Erich Baumgartner Lukas Pichler Dariya Baiko Karsten Wasmuth Johannes Heitz Marco Meyer Anna-Christin Joel Jorn Bonse Werner Baumgartner Institute of Biomedical Mechatronics, Johannes Kepler University Linz, Altenberger Straße 69, 4040 Linz, Austria Bundesanstalt