Preparation of alginate–chitosan–cyclodextrin micro- and nanoparticles loaded with anti-tuberculosis compounds

• Albert Ivancic,
• Fliur Macaev,
• Fatma Aksakal,
• Veaceslav Boldescu,
• Serghei Pogrebnoi and
• Gheorghe Duca

Beilstein J. Nanotechnol. 2016, 7, 1208–1218, doi:10.3762/bjnano.7.112

• addition to this, ISN has an antibacterial effect against gram-positive bacteria (B. cereus, C. tuberculostearicum, S. aureus MR, S. haemolyticus, S. hominis, and S. salivarius) confirmed by numerous reports on its antibacterial activity [21][22][23][24][25]. The antibacterial activity of ISN has been

Microwave solvothermal synthesis and characterization of manganese-doped ZnO nanoparticles

• Jacek Wojnarowicz,
• Roman Mukhovskyi,
• Elzbieta Pietrzykowska,
• Sylwia Kusnieruk,
• Jan Mizeracki and
• Witold Lojkowski

Beilstein J. Nanotechnol. 2016, 7, 721–732, doi:10.3762/bjnano.7.64

• , varistors, TFT display windows and laser technology [5][6][7]. ZnO displays pyroelectric and piezoelectric properties, thanks to which it is used in electroacoustic devices [8]. It is a biocompatible material used for producing biosensors and in drug delivery applications [9]. Thanks to antibacterial

Unraveling the neurotoxicity of titanium dioxide nanoparticles: focusing on molecular mechanisms

• Bin Song,
• Yanli Zhang,
• Jia Liu,
• Xiaoli Feng,
• Ting Zhou and
• Longquan Shao

Beilstein J. Nanotechnol. 2016, 7, 645–654, doi:10.3762/bjnano.7.57

• characteristics [1] including antibacterial, ultraviolet-absorbing, photocatalytic, and self-cleaning properties [2]. Thus, TiO2 NPs are widely used in cosmetics, sun screens, ceramics, paints, packaging, lithium batteries, the food industry, and in medical applications [3]. However, the rapid development of

Antibacterial activity of silver nanoparticles obtained by pulsed laser ablation in pure water and in chloride solution

• Brunella Perito,
• Emilia Giorgetti,
• Paolo Marsili and
• Maurizio Muniz-Miranda

Beilstein J. Nanotechnol. 2016, 7, 465–473, doi:10.3762/bjnano.7.40

• as antibacterial agents with applications in several fields due to their strong, broad-range antimicrobial properties. AgNP synthesis by pulsed laser ablation in liquid (PLAL) permits the preparation of stable Ag colloids in pure solvents without capping or stabilizing agents, producing AgNPs more

• also be affected by other parameters linked to the ablation conditions, such as the pulse width. The antibacterial activity of AgNPs was evaluated for NPs obtained either by nanosecond (ns) or picosecond (ps) PLAL using a 1064 nm ablation wavelength, in pure water or in LiCl aqueous solution, with

• -potential values were very negative, indicating excellent long-term colloidal stability. Antibacterial activity was observed against both microorganisms for the four AgNP formulations, but the ps-ablated nanoparticles were shown to more effectively inhibit the growth of both microorganisms. Moreover, LiCl

Surface coating affects behavior of metallic nanoparticles in a biological environment

• Darija Domazet Jurašin,
• Marija Ćurlin,
• Ivona Capjak,
• Tea Crnković,
• Marija Lovrić,
• Michal Babič,
• Daniel Horák,
• Ivana Vinković Vrček and
• Srećko Gajović

Beilstein J. Nanotechnol. 2016, 7, 246–262, doi:10.3762/bjnano.7.23

• currently in use for medical purposes [3], for example silver nanoparticles (AgNPs) and superparamagnetic iron oxide nanoparticles (SPIONs). AgNPs are exploited in medicine for biocidal therapy owing to their antibacterial, antifungal, antiviral, and anti-inflammatory properties. In addition, they attract

Sonochemical co-deposition of antibacterial nanoparticles and dyes on textiles

• Ilana Perelshtein,
• Anat Lipovsky,
• Nina Perkas,
• Tzanko Tzanov and
• Aharon Gedanken

Beilstein J. Nanotechnol. 2016, 7, 1–8, doi:10.3762/bjnano.7.1

• wide range of applications. Here, we report for the first time on the simultaneous sonochemical dyeing and coating of textiles with antibacterial metal oxide (MO) nanoparticles. In this one-step process the antibacterial nanoparticles are synthesized in situ and deposited together with dye

• nanoparticles on the fabric surface. It was shown that the antibacterial behavior of the metal oxides was not influenced by the presence of the dyes. Higher K/S values were achieved by sonochemical deposition of the dyes in comparison to a dip-coating (exhaustion) process. The stability of the antibacterial

• properties and the dye fastness was studied for 72 h in saline solution aiming at medical applications. Keywords: antibacterial nanoparticles; coating stability; dyes; sonochemical coating; Introduction The preferred technique for coating with nanoparticles (NPs) in most scientific and industrial examples

Blue and white light emission from zinc oxide nanoforests

• Nafisa Noor,
• Luca Lucera,
• Thomas Capuano,
• Venkata Manthina,
• Alexander G. Agrios,
• Helena Silva and
• Ali Gokirmak

Beilstein J. Nanotechnol. 2015, 6, 2463–2469, doi:10.3762/bjnano.6.255

• nanostructures [2], nanoscale electronic devices and large area electronics has led to significant research efforts in metal-oxide semiconductors such as ZnO. ZnO is a common, low-cost, antibacterial [3] material that forms various nanostructures depending on the process conditions. It is a direct and wide band

Ultrastructural changes in methicillin-resistant Staphylococcus aureus induced by positively charged silver nanoparticles

• Dulce G. Romero-Urbina,
• Humberto H. Lara,
• J. Jesús Velázquez-Salazar,
• M. Josefina Arellano-Jiménez,
• Eduardo Larios,
• Anand Srinivasan,
• Jose L. Lopez-Ribot and
• Miguel José Yacamán

Beilstein J. Nanotechnol. 2015, 6, 2396–2405, doi:10.3762/bjnano.6.246

• Abstract Silver nanoparticles offer a possible means of fighting antibacterial resistance. Most of their antibacterial properties are attributed to their silver ions. In the present work, we study the actions of positively charged silver nanoparticles against both methicillin-sensitive Staphylococcus

• polyanionic backbones of teichoic acids and the related cell wall glycopolymers of bacteria as a first target, consequently stressing the structure and permeability of the cell wall. This hypothesis provides a major mechanism to explain the antibacterial effects of silver nanoparticles on Staphylococcus

• , leading to structural strain in and permeability of the bacterial cell wall. This finding provides a major mechanism to explain the antibacterial properties of silver nanoparticles on Staphylococcus aureus. Results and Discussion Characterization of AgNPs TEM images of silver nanoparticles (Figure 1a

Green and energy-efficient methods for the production of metallic nanoparticles

• Mitra Naghdi,
• Mehrdad Taheran,
• Satinder K. Brar,
• M. Verma,
• R. Y. Surampalli and
• J. R. Valero

Beilstein J. Nanotechnol. 2015, 6, 2354–2376, doi:10.3762/bjnano.6.243

• exhibited higher thermal stability of Ag–CTS in comparison to CTS. Their microbial experiments showed that the antibacterial performance of Ag–CTS is more than either Ag NPs or CTS [72]. Sun et al. prepared Au NPs using HAuCl4 as a precursor and CTS as the reducing agent and stabilizer in a 30 h reaction at

• , 6, 24 and 48 h, respectively. According to the measured zeta potential of 54.5 mV, they concluded that the synthesized Ag NPs had acceptable stability [4]. In another study, they studied the antibacterial activity of different sizes of Ag NPs against two different bacteria and observed that Ag NPs

• with smaller size have a higher antibacterial activity [62]. Li et al. synthesized Ag NPs using PEG-200 as reducing and stabilizing agent and AgNO3 as precursor at ambient temperature within 6 h. Their analysis showed that the Ag NPs are spherical and stable for several weeks and the particle sizes are

Paramagnetism of cobalt-doped ZnO nanoparticles obtained by microwave solvothermal synthesis

• Jacek Wojnarowicz,
• Sylwia Kusnieruk,
• Tadeusz Chudoba,
• Stanislaw Gierlotka,
• Witold Lojkowski,
• Wojciech Knoff,
• Malgorzata I. Lukasiewicz,
• Bartlomiej S. Witkowski,
• Anna Wolska,
• Marcin T. Klepka,
• Tomasz Story and
• Marek Godlewski

Beilstein J. Nanotechnol. 2015, 6, 1957–1969, doi:10.3762/bjnano.6.200

• attractive material with a wide range of applications such as: transparent transistors based on semiconducting transparent oxides [4], ultraviolet (UV) light blockers [5], photocatalysts [6] or antibacterial uses [7]. The energy band gap of ZnO is ≈3.3 eV at room temperature, corresponding to a wavelength of

Synthesis, characterization and in vitro effects of 7 nm alloyed silver–gold nanoparticles

• Simon Ristig,
• Svitlana Chernousova,
• Wolfgang Meyer-Zaika and
• Matthias Epple

Beilstein J. Nanotechnol. 2015, 6, 1212–1220, doi:10.3762/bjnano.6.124

• bacteria [6][7][8]. As a result, they are often employed as antibacterial agents in biomedicine or in consumer products [9][10][11]. Unfortunately, the therapeutic window for silver nanoparticles is rather narrow as silver nanoparticles are also toxic towards eukaryotic cells [11][12]. In contrast, gold

Fulleropeptide esters as potential self-assembled antioxidants

• Mira S. Bjelaković,
• Tatjana J. Kop,
• Jelena Đorđević and
• Dragana R. Milić

Beilstein J. Nanotechnol. 2015, 6, 1065–1071, doi:10.3762/bjnano.6.107

• , Keller et al. [18] reported the synthesis of fullerenedihydropyrrole cationic peptides, which did not show antibacterial activity. Neuroprotective and antioxidant properties are based on the fact that fullerene derivatives possess an extended π-bond system, with high electron and free-radical species

Novel ZnO:Ag nanocomposites induce significant oxidative stress in human fibroblast malignant melanoma (Ht144) cells

• Syeda Arooj,
• Samina Nazir,
• Akhtar Nadhman,
• Nafees Ahmad,
• Bakhtiar Muhammad,
• Ishaq Ahmad,
• Kehkashan Mazhar and
• Rashda Abbasi

Beilstein J. Nanotechnol. 2015, 6, 570–582, doi:10.3762/bjnano.6.59

• antibacterial properties [12][13], are used in the cosmetics industry [14][15], and are used as nanoscale biosensors [11] and as drug carriers [16][17]. These NPs are being increasingly recognized due to their differential activity against tumor cells while being non-toxic to normal cells [18][19][20][21][22

• in the light source used, the percentage of Ag content or the cellular model used. Sharma et al. [32] reported zinc oxide nanoparticles with different formulations (0.1, 0.2, 0.3 and 0.4%) of Ag (size range: 23–59 nm) for their antibacterial activity and Shah et al. [33] reported that ZnO nanorods

Green preparation and spectroscopic characterization of plasmonic silver nanoparticles using fruits as reducing agents

• Jes Ærøe Hyllested,
• Marta Espina Palanco,
• Nicolai Hagen,
• Klaus Bo Mogensen and
• Katrin Kneipp

Beilstein J. Nanotechnol. 2015, 6, 293–299, doi:10.3762/bjnano.6.27

• catalyst, as antibacterial agents in medicine or plasmonic active structures in optical sensing and imaging [1][2][3][4][5][6]. These broad fields of applications generate a strong interest also in the preparation of metal nanoparticles. Many methods have been invented to synthesize nanoparticles, which

Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques

• Anja Ostrowski,
• Daniel Nordmeyer,
• Alexander Boreham,
• Cornelia Holzhausen,
• Lars Mundhenk,
• Christina Graf,
• Martina C. Meinke,
• Annika Vogt,
• Sabrina Hadam,
• Jürgen Lademann,
• Eckart Rühl,
• Ulrike Alexiev and
• Achim D. Gruber

Beilstein J. Nanotechnol. 2015, 6, 263–280, doi:10.3762/bjnano.6.25

• manifold. For example, nanomaterials find application in surgical implants to improve tissue formation or due to their antibacterial action, they may be useful for gene or drug delivery systems as well as diagnostic imaging tools [3][4][5][6][7]. On the other hand, due to the entirely new properties of NP

Nanobioarchitectures based on chlorophyll photopigment, artificial lipid bilayers and carbon nanotubes

• Marcela Elisabeta Barbinta-Patrascu,
• Stefan Marian Iordache,
• Ana Maria Iordache,
• Nicoleta Badea and
• Camelia Ungureanu

Beilstein J. Nanotechnol. 2014, 5, 2316–2325, doi:10.3762/bjnano.5.240

• radical scavenging ability (affording an antioxidant activity of 73.25%) and enhanced biocidal ability, offering inhibition zones of 12.4, 11.3 and 10.2 mm in diameter, against Escherichia coli, Staphylococcus aureus and Enterococcus faecalis, respectively. Keywords: antibacterial activity; antioxidant

• , which has been exploited in the preparation of anti-aging cosmetics and sunscreen creams to protect skin against free radicals formed by the body or by UV sunlight [10]. The goal of this work is to achieve antioxidant and antibacterial bionanomaterials based on liposomes and carbon nanotubes, which

• standard sample at t = 5 s, and I is the maximum CL intensity for a sample at t = 5 s [29]. Three measurements were performed for each sample in order to accurately evaluate the antioxidant activity. Antibacterial assay The antibacterial activity of the samples was tested against Gram-positive and Gram

Biopolymer colloids for controlling and templating inorganic synthesis

• Laura C. Preiss,
• Katharina Landfester and
• Rafael Muñoz-Espí

Beilstein J. Nanotechnol. 2014, 5, 2129–2138, doi:10.3762/bjnano.5.222

• ” geometries. In a very recent work, Taheri et al. [63] have presented the formation of potato starch capsules decorated with silver nanoparticles, which could have applications as drug carriers or antibacterial coatings. The capsules are prepared in an inverse (water-in-oil) miniemulsion and the surfactant

• supercritical CO2 and subsequent calcination. Scaffold templating can also be achieved with starch and even with peptides. Thakore et al. [13] synthesized Cu, Ag, and Cu–Ag alloy nanoparticles in a matrix of starch through a green route and studied the antibacterial activity. Hexagonal silica platelets were

Effect of silver nanoparticles on human mesenchymal stem cell differentiation

• Christina Sengstock,
• Jörg Diendorf,
• Matthias Epple,
• Thomas A. Schildhauer and
• Manfred Köller

Beilstein J. Nanotechnol. 2014, 5, 2058–2069, doi:10.3762/bjnano.5.214

• of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany 10.3762/bjnano.5.214 Abstract Background: Silver nanoparticles (Ag-NP) are one of the fastest growing products in nano-medicine due to their enhanced antibacterial activity at the nanoscale level. In biomedicine, hundreds of products

• contact with tissues and cells. Despite incorporation of Ag-NP as an antibacterial agent in different products, the toxicological and biological effects of silver in the human body after long-term and low-concentration exposure are not well understood. In the current study, we investigated the effects of

• (osteoblasts). Conclusion: Aside from the well-studied antibacterial effect of silver, little is known about the influence of nano-silver on cell differentiation processes. Our results demonstrate that ionic or nanoparticulate silver attenuates the adipogenic and osteogenic differentiation of hMSCs even at non

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

• Sebastian Ahlberg,
• Alexandra Antonopulos,
• Jörg Diendorf,
• Ralf Dringen,
• Matthias Epple,
• Rebekka Flöck,
• Wolfgang Goedecke,
• Christina Graf,
• Nadine Haberl,
• Jens Helmlinger,
• Fabian Herzog,
• Frederike Heuer,
• Stephanie Hirn,
• Christian Johannes,
• Stefanie Kittler,
• Manfred Köller,
• Katrin Korn,
• Wolfgang G. Kreyling,
• Fritz Krombach,
• Jürgen Lademann,
• Kateryna Loza,
• Eva M. Luther,
• Marcelina Malissek,
• Martina C. Meinke,
• Daniel Nordmeyer,
• Anne Pailliart,
• Jörg Raabe,
• Fiorenza Rancan,
• Barbara Rothen-Rutishauser,
• Eckart Rühl,
• Carsten Schleh,
• Andreas Seibel,
• Christina Sengstock,
• Lennart Treuel,
• Annika Vogt,
• Katrin Weber and
• Reinhard Zellner

Beilstein J. Nanotechnol. 2014, 5, 1944–1965, doi:10.3762/bjnano.5.205

• its well-known antibacterial action. However, there are increasing concerns about potential risks to humans and to the environment, especially in the case of silver nanoparticles [12][13][14][15][16][17][18][19]. The assessment of the physicochemical and biological properties of silver nanoparticles

• production and the manufacture of nanoparticle-containing materials. However, since the antibacterial properties of silver nanoparticles and silver salts promote an increased use in personal care products, aerosolized silver nanoparticles and silver salts in spray products such as deodorants or

• effects, such as cytotoxicity and/or (pro-)inflammatory responses are only induced by higher concentrations of silver nanoparticles. Interaction of silver nanoparticles with the human skin barrier and keratinocytes Silver is widely used in dermatology and health care as antibacterial and anti-inflammatory

Microstructural and plasmonic modifications in Ag–TiO₂ and Au–TiO₂ nanocomposites through ion beam irradiation

• Venkata Sai Kiran Chakravadhanula,
• Yogendra Kumar Mishra,
• Venkata Girish Kotnur,
• Devesh Kumar Avasthi,
• Thomas Strunskus,
• Vladimir Zaporotchenko,
• Dietmar Fink,
• Lorenz Kienle and
• Franz Faupel

Beilstein J. Nanotechnol. 2014, 5, 1419–1431, doi:10.3762/bjnano.5.154

• , antibacterial coatings, photocatalysts, and implants [13][14][15][16][17][18]. The different properties of metal–TiO2 nanocomposites mainly depend on the metal volume filling fraction and the stoichiometry of the matrix. Generally, once the nanocomposites are prepared their properties are fixed. It is therefore

DFT study of binding and electron transfer from colorless aromatic pollutants to a TiO₂ nanocluster: Application to photocatalytic degradation under visible light irradiation

• Corneliu I. Oprea,
• Petre Panait and
• Mihai A. Gîrţu

Beilstein J. Nanotechnol. 2014, 5, 1016–1030, doi:10.3762/bjnano.5.115

• ][10]. The assumption of a surface CTC in the visible light catalysis was supported by subsequent work on various other types of systems, such as phenolic compounds [11][12], fluoroquinolone antibacterial agents [13], and various colorless aromatic pollutants [14]. Despite the extensive experimental

Antimicrobial properties of CuO nanorods and multi-armed nanoparticles against B. anthracis vegetative cells and endospores

• Pratibha Pandey,
• Merwyn S. Packiyaraj,
• Himangini Nigam,
• Gauri S. Agarwal,
• Beer Singh and
• Manoj K. Patra

Beilstein J. Nanotechnol. 2014, 5, 789–800, doi:10.3762/bjnano.5.91

• a large number of gram-positive and gram-negative bacteria [16]. CuO nanostructures were reported as potential antibacterial agents by other groups as well [17][18][19][20]. Trapalis et al. [17] and Akhavan et al. [18] reported CuO–SiO2 composite thin film and CuO/Cu(OH)2 nanostructure, respectively

• , generated on copper foil as effective antibacterial against E. coli bacteria when the bacterial suspension drop was tested on these surfaces. Perelshtein et al. [19] have reported antibacterial CuO-cotton textile against E. coli and S. aureus. Gao et al. [20] reported strong antibacterial activity of CuO

• nanostructures comparable to established antibiotics as well as their photocatalytic potential. However, we have not come across any report on bactericidal potential of CuO nanoparticles against B. anthracis cells and spores. The earlier findings inspired us to evaluate antibacterial activity of noncorrosive CuO

An ultrasonic technology for production of antibacterial nanomaterials and their coating on textiles

• Anna V. Abramova,
• Vladimir O. Abramov,
• Aharon Gedanken,
• Ilana Perelshtein and
• Vadim M. Bayazitov

Beilstein J. Nanotechnol. 2014, 5, 532–536, doi:10.3762/bjnano.5.62

• , Israel 10.3762/bjnano.5.62 Abstract A method for the production of antibacterial ZnO nanoparticles has been developed. The technique combines passing an electric current with simultaneous application of ultrasonic waves. By using high-power ultrasound a cavitation zone is created between two zinc

• electrodes. This leads to the possibility to create a spatial electrical discharge in water. Creation of such discharge leads to the depletion of the electrodes and the formation of ZnO nanoparticles, which demonstrate antibacterial properties. At the end of this reaction the suspension of ZnO nanoparticles

• the surface of textile at very high velocities. Fabrics coated with ZnO nanoparticles by using the developed method showed good antibacterial activity against E. coli. Keywords: antibacterial textile; cavitation; electrical discharge in liquid; nanoparticle; ultrasound; Introduction Currently, the

New hybrid materials based on poly(ethyleneoxide)-grafted polysilazane by hydrosilylation and their anti-fouling activities

• Thi Dieu Hang Nguyen,
• François-Xavier Perrin and
• Dinh Lam Nguyen

Beilstein J. Nanotechnol. 2013, 4, 671–677, doi:10.3762/bjnano.4.75

• surface is approximately equal, the relative effectiveness of these two types of PEO is controlled by the length of the PEO chain. The PEO(2000 g/mol)-graft-PSZ coatings are more efficient than the PEO(750 g/mol)-graft-PSZ coatings for the bacterial anti-adhesion. Keywords: antibacterial; hybrid

Photocatalytic antibacterial performance of TiO₂ and Ag-doped TiO₂ against S. aureus. P. aeruginosa and E. coli

• Kiran Gupta,
• R. P. Singh,
• Ashutosh Pandey and
• Anjana Pandey

Beilstein J. Nanotechnol. 2013, 4, 345–351, doi:10.3762/bjnano.4.40

• indirect optical band gap of 3.2 eV, while the rutile phase has a direct band gap of 3.06 eV and an indirect one of 3.10 eV [7]. However, crude nanoparticles are amorphous in nature, with decreased surface area, and show a fast recombination rate of electrons and holes. Finally the antibacterial activity

• acid-catalyzed sol–gel technique. The prepared particles were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), ultraviolet visible spectroscopy (UV–vis) and photoluminescence (PL). Furthermore, the antibacterial activity of the TiO2 and Ag-TiO2 nanoparticles were

• killing of the bacteria investigated here. The antibacterial activity of annealed samples is slightly more than crude TiO2, because after annealing at 450 °C the amorphous phase of the nanoparticle is converted to both anatase and rutile phases, and shows an indirect band gap of 3.2 eV, which is similar