Nanotechnological approaches in the treatment of schistosomiasis: an overview

• Lucas Carvalho,
• Michelle Sarcinelli and
• Beatriz Patrício

Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2

• sublethal doses can cause alterations in parasite tegument [85]. Bee venom comprises various pharmacologically active components, including melittin (constituting more than 50% of total proteins) and a mixture of enzymes, cell-lytic peptides, proteases, and bioactive amines [86]. This mixture has

Metal-organic framework-based nanomaterials for CO₂ storage: A review

• Ha Huu Do,
• Iqra Rabani and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 964–970, doi:10.3762/bjnano.14.79

• frameworks (MOFs) [11][12][13]. Notably, MOFs constructed from metal ions and organic linkers are expected to be alternative materials to the organic alcohol amines in CCS [14]. These nanosized materials posess unique properties such as ultrahigh surface area, tunable pore size, open metal sites (OMSs), and

• . In a recent study, Gaikwad et al. modified MOF-177 nanoparticles using three different amines to enhance the amount of absorbed CO2 [37]. The optimally functionalized MOF-177, employing tetraethylenepentamine (TEPA), exhibited a remarkably higher amount of absorbed CO2 than bare MOF-177 under the

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• the reduction of disulfide bonds. Thiols, also called sulfhydryls, in the cysteine side chain are slightly less abundant than primary amines; therefore, the coupling by thiol groups is more selective [52]. Thiols in cysteines are linked by disulfide bonds (–S–S–) through an oxidation process where the

• proteins that do not have free thiol groups, such groups can be generated either by reducing the disulfide bonds (DTT and BME) or by introducing cysteine residues (Traut’s reagent and N-succinimidyl S-acetylthioacetate) at different positions. The reaction with primary amines or the reduction of disulfide

• bonds of the antibodies form free thiol groups. The free thiol groups of the antibody can be linked to the primary amines on NP surfaces using SMCC, sulfo-SMCC, and their analogues via maleimide coupling (Figure 4b). These crosslinkers react specifically with thiol groups at pH 6.5 to 7.5 and form

Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine

• Zoran M. Marković,
• Milica D. Budimir,
• Martin Danko,
• Dušan D. Milivojević,
• Pavel Kubat,
• Danica Z. Zmejkoski,
• Vladimir B. Pavlović,
• Marija M. Mojsin,
• Milena J. Stevanović and
• Biljana M. Todorović Marković

Beilstein J. Nanotechnol. 2023, 14, 165–174, doi:10.3762/bjnano.14.17

• amines such as 2-ethylenediamine, poly(ethyleneamine), or trimethylamine, enhances the affinity of CQDs to biological structures whereas incorporation of nitrogen atoms in the honeycomb structure of CQDs contributes to a reduction of photobleaching [7]. Tepliakov et al. reported that CQDs can be treated

• assigned to N–H stretching vibrations of aliphatic primary amines whereas the peaks at 2880 and 2943 cm−1 originate from C–H stretching vibrations. A peak at 1759 cm−1 stems from C=O stretching vibrations (carboxylic acid) whereas the peaks at 1696 and 1593 cm−1 could be assigned to C=N stretching and N–H

Two-step single-reactor synthesis of oleic acid- or undecylenic acid-stabilized magnetic nanoparticles by thermal decomposition

• Mykhailo Nahorniak,
• Pamela Pasetto,
• Jean-Marc Greneche,
• Volodymyr Samaryk,
• Sandy Auguste,
• Anthony Rousseau,
• Nataliya Nosova and
• Serhii Varvarenko

Beilstein J. Nanotechnol. 2023, 14, 11–22, doi:10.3762/bjnano.14.2

• low stability (i.e., acetate, pentacarbonyl, acetylacetonate) in high-boiling-point solvents in the presence of stabilizing agents (e.g., fatty acids, higher amines, alcohols) or their mixtures [13][14][15]. Although thermal decomposition is a relatively simple method, minor modifications of the

Supramolecular assembly of pentamidine and polymeric cyclodextrin bimetallic core–shell nanoarchitectures

• Alexandru-Milentie Hada,
• Nina Burduja,
• Marco Abbate,
• Claudio Stagno,
• Guy Caljon,
• Louis Maes,
• Nicola Micale,
• Massimiliano Cordaro,
• Angela Scala,
• Antonino Mazzaglia and
• Anna Piperno

Beilstein J. Nanotechnol. 2022, 13, 1361–1369, doi:10.3762/bjnano.13.112

• ability of the β-cyclodextrin polymer (PolyCD) to act as a symbiont of both MNPs and BMNPs [14]. Specifically, functional groups of PolyCD (i.e., amines, primary and secondary alcohols, and hemiacetals) are involved in the direct reduction of gold ions to Au NPs (Figure 1). PolyCD-capped Au NPs showed an

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• the complexation process of various chiral calix[4]arenes derivatives with gas-phase R/S-1-phenethylamine [78]. They proved that due to the acid–base interaction, only derivatives with acid could bind well with chiral amines. The other derivatives with esters, amides, and alcohols showed low

• promoted the combination of S-1-phenethylamine, while the ortho-position may combine with R-1-phenethylamine. The QCM results were consistent with the data from 1H NMR spectroscopy. Moreover, the QCM method may also allow for the detection of weak interactions of amides and esters with amines and a slight

Gelatin nanoparticles with tunable mechanical properties: effect of crosslinking time and loading

• Agnes-Valencia Weiss,
• Daniel Schorr,
• Julia K. Metz,
• Metin Yildirim,
• Saeed Ahmad Khan and
• Marc Schneider

Beilstein J. Nanotechnol. 2022, 13, 778–787, doi:10.3762/bjnano.13.68

• to quantify the degree of crosslinking by determining free lysine in the particles. Colorimetric determination with trinitrobenzenesulfonic acid (TNBS) is a common method [26]. Under alkaline conditions, the primary amines and TNBS react to trinitrophenyl derivatives and sulfite. The formed compound

• can be quantitatively measured by UV–vis spectrometry at a wavelength of λ = 349 nm related to the number of primary amines present in the equal amount of uncrosslinked gelatin. In brief, the method was as follows: 10 to 12 mg of freeze-dried particles was resuspended in 1 mL of a 4% NaHCO3 solution

Theranostic potential of self-luminescent branched polyethyleneimine-coated superparamagnetic iron oxide nanoparticles

• Rouhollah Khodadust,
• Ozlem Unal and
• Havva Yagci Acar

Beilstein J. Nanotechnol. 2022, 13, 82–95, doi:10.3762/bjnano.13.6

• the backbone, acidification of amines, hydrogen bonding, exciplex formation, amine oxidation, and solvent-induced aggregation were reported as factors that amplify the weak luminescence of PEI and amine-containing dendrimers [15][16][17][18][20][24]. The luminescence of these materials is especially

• amines during the synthesis of SPION@bPEI is responsible for the enhanced bPEI luminescence. It is further enhanced with the immobilization of bPEI on SPION crystals and post-synthetic acidification of the particles, which also increased the rigidity. These nanoparticles have a small hydrodynamic size

• of Erb to nanoparticles consumed some amines, and the antibody contains anionic functionalities as well. The Erb conjugation decreased the luminescence intensity of SPION@bPEI by approx. 30%, but PIC loading (Figure 2b) or DNA loading did not change the luminescence intensity any further (Supporting

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

• metal precursor, usually a salt such as HAuCl4, is chemically reduced by a (ii) reagent (e.g., sodium citrate, sodium borohydrate, ascorbic acid, glucose, hydrazine, or various amines) in the presence of a (iii) stabilizing agent (e.g., organic thiols, amines, acids, or various surfactants, i.e

pH-driven enhancement of anti-tubercular drug loading on iron oxide nanoparticles for drug delivery in macrophages

• Karishma Berta Cotta,
• Sarika Mehra and
• Rajdip Bandyopadhyaya

Beilstein J. Nanotechnol. 2021, 12, 1127–1139, doi:10.3762/bjnano.12.84

• of Fe–O stretching, from the IONPs, along with characteristic peaks of amines. C–F, N–H bending of quinolones and N–H stretching of piperazinyl were observed at 550–650, 1000–1050, 1650 and 3300–3500 cm−1, indicating the presence of NOR (Figure 3d) [36][37][38]. It was noted that the N–H stretching

Revealing the formation mechanism and band gap tuning of Sb₂S₃ nanoparticles

• Maximilian Joschko,
• Franck Yvan Fotue Wafo,
• Christina Malsi,
• Danilo Kisić,
• Ivana Validžić and
• Christina Graf

Beilstein J. Nanotechnol. 2021, 12, 1021–1033, doi:10.3762/bjnano.12.76

•  6b, and Figures S6 and S7 in Supporting Information File 1). The nonstoichiometric Sb/S ratio in the early reaction stage was probably due to the oleylamine used in the synthesis. Several authors have already described that hydrolysis of antimony in fatty amines can lead to the formation of Sb2O3 [33

A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures

• Sina Kaabipour and
• Shohreh Hemmati

Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9

Straightforward synthesis of gold nanoparticles by adding water to an engineered small dendrimer

• Sébastien Gottis,
• Régis Laurent,
• Vincent Collière and
• Anne-Marie Caminade

Beilstein J. Nanotechnol. 2020, 11, 1110–1118, doi:10.3762/bjnano.11.95

• fibers stabilized by amines (AuI, ca. 3.25 Å) [10], but slightly longer than in the case of gold particles in silica glass and gold foil (2.84 Å) [61] or in bulk gold (2.88427 Å) [10]. The dependence between the gold nanoparticle shape and the conditions in which they were generated is the subject of a

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

• Maria Suciu,
• Corina M. Ionescu,
• Alexandra Ciorita,
• Septimiu C. Tripon,
• Dragos Nica,
• Hani Al-Salami and
• Lucian Barbu-Tudoran

Beilstein J. Nanotechnol. 2020, 11, 1092–1109, doi:10.3762/bjnano.11.94

• -coated SPIONs are biocompatible, but a higher number of amines in the coating is not compatible with the animal metabolism [84]. Even so, Strehl et al. [26] concluded in their paper that PVA-coated SPIONs with amines had no toxic effect on immune cells. Instead, they actually determined a viability

Gas-sensing features of nanostructured tellurium thin films

• Dumitru Tsiulyanu

Beilstein J. Nanotechnol. 2020, 11, 1010–1018, doi:10.3762/bjnano.11.85

• microcrystalline Te films have remarkable, sensitive properties toward ammonia [8][9] and hydrogen sulfide [10] and, to a lesser extent, to carbon oxides and amines [11]. In the last years, due to the increase in the general interest toward nanodimensional devices and structures, significant attention has been

A 3D-polyphenylalanine network inside porous alumina: Synthesis and characterization of an inorganic–organic composite membrane

• Jonathan Stott and
• Jörg J. Schneider

Beilstein J. Nanotechnol. 2020, 11, 938–951, doi:10.3762/bjnano.11.78

• polycondensation reactions [42][43][44][45][46]. In the activated monomer mechanism, the N–H proton is removed from the NCA-monomer by a base (e.g. tertiary amines), leading to the formation of a NCA-anion. We assume that the amino groups in the amino silane film may act as sterically hindered tertiary amines. The

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

• between epoxides and amines resulted in ultrathin, smooth and highly cross-linked structures for poly(glycidyl methylacrylate) (PGMA)/PAH hollow capsules fabricated over SiO2 templates [56]. These capsules were stable at extreme pH conditions (1.2–12.8) and elevated temperatures showing an elastic modulus

• polymeric structure [87]. The pH control helped the self-assembled capsules in precipitation and dissolution by trapping of guest molecules inside. Furthermore, it led to a new strategy involving hydrogen bonding and carbamate chemistry (between carbon dioxide and amines) which resulted in supramolecular

Preparation and in vivo evaluation of glyco-gold nanoparticles carrying synthetic mycobacterial hexaarabinofuranoside

• Gennady L. Burygin,
• Polina I. Abronina,
• Nikita M. Podvalnyy,
• Sergey A. Staroverov,
• Leonid O. Kononov and
• Lev A. Dykman

Beilstein J. Nanotechnol. 2020, 11, 480–493, doi:10.3762/bjnano.11.39

• yet. Indeed, the direct conjugation of amino-functionalized antigenic glycans with pre-formed GNPs has not been reported yet, to the best of our knowledge. This is despite the fact that simple amines, amino acids and peptides [68][69][70][71][72][73][74][75][76][77][78], as well as diethylaminoethyl

• ], which enables the exchange of citrate ligands with amines. The amine-capped GNPs are stable enough to be used as targeting agents for drug-delivery applications [75], as antigens for the generation of antibodies [77], or as antimicrobial agents [78]. These nanoconjugates are nontoxic, effectively

• uptake of glycans incorporated in glyco-GNPs since free glycans (haptens) cannot be phagocytosed per se due to their small size. Probably, the substitution of glycans on the surface of glyco-GNPs with endogenous cellular thiols and amines facilitates the subsequent translocation of glycans to the surface

Interfacial charge transfer processes in 2D and 3D semiconducting hybrid perovskites: azobenzene as photoswitchable ligand

• Nicole Fillafer,
• Tobias Seewald,
• Lukas Schmidt-Mende and
• Sebastian Polarz

Beilstein J. Nanotechnol. 2020, 11, 466–479, doi:10.3762/bjnano.11.38

• [45]. It is well known, that vibrations of surface-bound amines are quenched through coordination. Signals at 832, 765, 727 and 685 cm−1 can be assigned to the aromatic vibrations of the phenyl rings of azobenzene. These significant vibrations can as well be found in 3D-AzoC2 (blue), which indicates a

• -CH2-NH2), 1.87 (p, 2H, CH2-CH2-CH2), 1.65 (p, 2H, CH2-CH2-CH2); (400 MHz, CDCl3) n = 12: δ 7.91–7.86 (m, 4H, CN=CH-CH), 7.51–7.40 (m, 3H, CH-CH=CH), 7.00 (d, 2H, CH-CH=CO), 4.03 (t, 2H, O-CH2-CH2), 2.75 (t, 2H, CH2-CH2-NH2), 1.81 (m, 2H), 1.57–1.43 (m, 4H), 1.28 (s, 14H). All amines were further

Rational design of block copolymer self-assemblies in photodynamic therapy

• Maxime Demazeau,
• Laure Gibot,
• Anne-Françoise Mingotaud,
• Patricia Vicendo,
• Clément Roux and
• Barbara Lonetti

Beilstein J. Nanotechnol. 2020, 11, 180–212, doi:10.3762/bjnano.11.15

• the self-assemblies, followed by cargo release [56]. These well-known concepts in nanomedicine have been applied to photodynamic therapy applications. A responsiveness to the pH value can be induced by inserting ionisable groups (such as amines and carboxylic acids for example) in the polymer backbone

The different ways to chitosan/hyaluronic acid nanoparticles: templated vs direct complexation. Influence of particle preparation on morphology, cell uptake and silencing efficiency

• Arianna Gennari,
• Julio M. Rios de la Rosa,
• Erwin Hohn,
• Maria Pelliccia,
• Enrique Lallana,
• Roberto Donno,
• Annalisa Tirella and
• Nicola Tirelli

Beilstein J. Nanotechnol. 2019, 10, 2594–2608, doi:10.3762/bjnano.10.250

• chitosan-based nanoparticles [5][6][7][8], the most popular being ionotropic gelation and polyelectrolyte complexation. The distinction between the two is subtle, since they are based on a common driving force, i.e., the electrostatic attraction between protonated amines on chitosan and multiply charged

• solution the protonated chitosan amines (cationic species in red) are cross-linked by TPP (anionic species in blue). The complexation leads to the nucleation of the particles that increase in size likely more through the adsorption of additional chitosan and TPP species (growth) than through aggregation of

Review of advanced sensor devices employing nanoarchitectonics concepts

• Katsuhiko Ariga,
• Tatsuyuki Makita,
• Masato Ito,
• Taizo Mori,
• Shun Watanabe and
• Jun Takeya

Beilstein J. Nanotechnol. 2019, 10, 2014–2030, doi:10.3762/bjnano.10.198

• fluorescent gelators containing a tris(β-diketonato) complex with appropriate metals. The presence of amines can be found through fluorescence-quenching efficiencies of the thin layer films of the gel materials. The prepared films are most sensitive to the detection of tertiary amines. The discrimination and

• interaction and faint differences. Kim and co-workers fabricated sensor arrays that were engineered with fluorescence dyes and cucurbit[n]urils (n = 6, 7 and 8) as host systems [91]. The obtained sensors were used for sensing biogenic amines with the aid of principal component analysis. This

Processing nanoporous organic polymers in liquid amines

• Jeehye Byun,
• Damien Thirion and
• Cafer T. Yavuz

Beilstein J. Nanotechnol. 2019, 10, 1844–1850, doi:10.3762/bjnano.10.179

• challenging. Herein, we report that nanoporous polymers made via a Knoevenagel-like condensation can be easily processed into nanoparticles (115.7 ± 40.8 nm) or a flawless film by using liquid amines as a solvent at elevated temperatures. FTIR spectra revealed that the carboxyl groups in the nanoporous

• polymers act as reactive sites for amines, forming new functionalities and spacing the polymeric chains to be dissolved in the liquid amines. The processed film was found to be CO2-philic despite the low surface area, and further able to be transformed into a fine carbon film by thermal treatment

• fabricated into nanoparticles and films. In this work, nanoporous polymers built via Knoevenagel-like condensations are made to be soluble in liquid amines and show structural processibility. At elevated temperatures (ca. 100 °C), the condensate nanoporous polymers were completely dissolved in neat liquid

A biomimetic nanofluidic diode based on surface-modified polymeric carbon nitride nanotubes

• Kai Xiao,
• Baris Kumru,
• Lu Chen,
• Lei Jiang,
• Bernhard V. K. J. Schmidt and
• Markus Antonietti

Beilstein J. Nanotechnol. 2019, 10, 1316–1323, doi:10.3762/bjnano.10.130

• and Discussion Fabrication of carbon nitride nanotube membrane Graphitic carbon nitride (g-CN) was chosen as it is formed from tri-s-triazine moieties interconnected via tertiary amines in a well-defined way without doping or modification, composed of only the two earth-abundant elements carbon and