Toward clinical translation of carbon nanomaterials in anticancer drug delivery: the need for standardisation

• Michał Bartkowski,
• Francesco Calzaferri and
• Silvia Giordani

Beilstein J. Nanotechnol. 2025, 16, 2092–2104, doi:10.3762/bjnano.16.144

• delivery systems (DDSs); nanocarriers; quality control (QC); Introduction Nanomaterials Nanomaterials (NMs) have an extensive array of various properties and applications across many industries, including the biomedical, health care, food/agriculture, industrial, environmental, electronic, and renewable

Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• heterogeneous nanomaterials while significantly simplifying the requirements for probe selection, which are typically necessary for material differentiation via the standard PeakForce tapping method. This innovation enhances the technique’s practicality and extends compatibility to a wider array of probe types

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• various biomedical applications [28][29]. Complementing the regenerative and biocompatible profile of HA, β-caryophyllene (βCp) is another critical component of significant pharmaceutical potential. Among the array of attributes exhibited by βCp, it notably possesses potent analgesic, antioxidant

Quantum circuits with SINIS structures

• Mikhail Tarasov,
• Mikhail Fominskii,
• Aleksandra Gunbina,
• Artem Krasilnikov,
• Maria Mansfeld,
• Dmitrii Kukushkin,
• Andrei Maruhno,
• Valeria Ievleva,
• Mikhail Strelkov,
• Daniil Zhogov,
• Konstantin Arutyunov,
• Vyacheslav Vdovin,
• Vladislav Stolyarov and
• Valerian Edelman

Beilstein J. Nanotechnol. 2025, 16, 1931–1941, doi:10.3762/bjnano.16.134

• a physical temperature of 0.26 K. The array structure was mounted in back-to-back horn matching structure with an optimum for 95 GHz and corresponding quasi-optical band-pass filters (Figure 9). I–V curves and dynamic resistances are presented in Figure 10a. The resistance ratio is 46, which

• responsivity up to 109 V·W−1, array of NIS thermometers provide sensitivity down to 10 µK, electron coolers can reduce the electron temperature of a normal metal absorber from 280 mK down to 100 mK, and the SINIS receiver for a frequency of 95 GHz was installed on the BTA telescope and tested at a temperature

• series array. (a) Schematic view of a thermometer with a chain of 20 NIS junctions and SEM images of thermometers made by (b) Manhattan technology and (c) magnetron sputtering with separate lithography technology. (a) Ratio of resistance at zero bias to the asymptotic resistance using Equation 7

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease

• Niédja Fittipaldi Vasconcelos,
• Almerinda Agrelli,
• Rayane Cristine Santos da Silva,
• Carina Lucena Mendes-Marques,
• Isabel Renata de Souza Arruda,
• Priscilla Stela Santana de Oliveira,
• Mércia Liane de Oliveira and
• Giovanna Machado

Beilstein J. Nanotechnol. 2025, 16, 1711–1733, doi:10.3762/bjnano.16.120

• - and bilayers) form due to the diverse array of fatty acids in lecithin, the positioning and unsaturation of which are not provided by the manufacturer. Therefore, experimental tests on lecithin concentration are necessary to achieve a monolayer, nanometric, uniform, and stable micellar structural

Transient electronics for sustainability: Emerging technologies and future directions

• Jae-Young Bae,
• Myung-Kyun Choi and
• Seung-Kyun Kang

Beilstein J. Nanotechnol. 2025, 16, 1545–1556, doi:10.3762/bjnano.16.109

• the clinical utility of such systems. Notably, devices based on biodegradable shape memory materials can be compactly delivered through narrow anatomical pathways and subsequently recover their functional form in vivo. A prominent example is a large-area transient electrocorticography array that

• include materials with diverse bandgap properties remains a key challenge as it would enable wavelength-specific and electrically optimized device designs across a wide array of applications, including sensors, radio frequency (RF) devices, energy harvesters, and optoelectronic systems. For instance, low

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• inspired coatings derived from cell membranes with nanoparticle cores, these carriers become highly versatile vessels for encapsulating a wide array of therapeutic agents. As a result, they are being extensively harnessed for the precise delivery of drugs and genes, underpinning numerous biomedical

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• nanotechnology and materials sciences, encompassing a vast array of disciplines. These include, but are not limited to, both hard and soft materials. The research objectives and applications of nanoarchitectonics are diverse. The term “nanoarchitectonics” has been used in the titles of numerous publications

• other materials into layers [255][256][257][258][259]. Polymer materials are of significant value as components of soft materials, and can be employed in the creation of a vast array of structures. The following section will present examples of research into polymer-based soft materials

Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus

• Carlos Enrique Torres-Méndez,
• Sharmilee Nandi,
• Klara Martinovic,
• Patrizia Kühne,
• Yifan Liu,
• Sam Taylor,
• Maria Lysandrou,
• Maria Ines Berrojo Romeyro Mascarenhas,
• Viktoria Langwallner,
• Javier Enrique Sebastián Alonso,
• Ivana Jovanovic,
• Maike Lüftner,
• Georgia-Vasiliki Gkountana,
• David Bern,
• Abdul-Raouf Atif,
• Ehsan Manouchehri Doulabi,
• Gemma Mestres and
• Masood Kamali-Moghaddam

Beilstein J. Nanotechnol. 2025, 16, 540–550, doi:10.3762/bjnano.16.42

• after exposing the biosensor to blank solutions of artificial saliva without H1 protein. Electrochemical measurements The commercial CSPE employed in this study consists of a three-electrode cell array with a carbon working electrode, a Ag/AgCl reference electrode, and a carbon counter electrode

Biomimetics and bioinspired surfaces: from nature to theory and applications

• Rhainer Guillermo Ferreira,
• Thies H. Büscher,
• Manuela Rebora,
• Poramate Manoonpong,
• Zhendong Dai and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2025, 16, 418–421, doi:10.3762/bjnano.16.32

• influence their performance and at drawing inspiration for modern technology from the vast array of solutions found in nature [1]. By examining the multiscale structures and mechanisms in biological systems, innovative and technologically advanced solutions can be developed for practical applications

• species. Other possible sources of bioinspiration have been extensively examined by a review on functional surfaces in Hymenoptera, which include bees, wasps, and ants [5]. This diverse group of insects offers a rich array of surfaces that are adapted to realize different tasks, providing insights into

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

• Shushanik A. Kazaryan,
• Seda A. Oganian,
• Gayane S. Vardanyan,
• Anatolie S. Sidorenko and
• Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

• an orbital shaker (60–70 rpm), the mixture was centrifuged for 15 min at 3000 rpm (Jouan GR412, France) [50]. HPLC analysis of plant extracts To determine the major polyphenols, HPLC was employed using a Waters Alliance 2695 chromatograph with a spectrophotometric diode array detector, as well as

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

• Dimitra-Danai Varsou,
• Arkaprava Banerjee,
• Joyita Roy,
• Kunal Roy,
• Giannis Savvas,
• Haralambos Sarimveis,
• Ewelina Wyrzykowska,
• Mateusz Balicki,
• Tomasz Puzyn,
• Georgia Melagraki,
• Iseult Lynch and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

• ; read-across; QSPR; round-robin test; zeta potential; Introduction Nanotechnology, defined as the ability to manipulate matter at the nanoscale, has opened an array of possibilities for multiple applications that take advantage of the unique properties of nanomaterials (NMs). From targeted drug

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• compounds, and antimicrobials, offering a natural and multifaceted arsenal for combating a wide array of diseases [6][7][8]. Despite their promising bioactivities, the clinical application of phytochemicals is often limited by several inherent drawbacks such as poor water solubility, low bioavailability

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• extraordinary adaptations that Hymenoptera (sawflies, wasps, ants, and bees) exhibit on their body surfaces has long intrigued biologists. These adaptations, which enabled the immense success of these insects in a wide range of environments and habitats, include an amazing array of specialized structures

• surfaces of insects are marvels of natural engineering, displaying a remarkable array of adaptations that enable them to thrive in diverse environments [1][2][3]. Insects have developed a variety of mechanisms to cope with the challenges posed by their habitats, from specialized structures for attachment

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol

• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 1312–1332, doi:10.3762/bjnano.15.106

• . Quantification of CTAB through UHPLC The quantification of bound CTAB on the nanoparticles’ surface was analyzed using ultrahigh-performance liquid chromatography (UHPLC; Shimadzu, Nexera, Tokyo, Japan). The chromatography system equipped with an SPD-M20A photodiode array (PDA) detector with a wavelength range

Photocatalytic methane oxidation over a TiO₂/SiNWs p–n junction catalyst at room temperature

• Qui Thanh Hoai Ta,
• Luan Minh Nguyen,
• Ngoc Hoi Nguyen,
• Phan Khanh Thinh Nguyen and
• Dai Hai Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1132–1141, doi:10.3762/bjnano.15.92

• surface interaction with gases during photocatalytic oxidative coupling can be analyzed using water contact angle analysis (as shown in Supporting Information File 1, Figure S2). The wettability of pure p-Si and the p-Si NW array are illustrated in Figure S3 (Supporting Information File 1). Pure p-Si had

• a water contact angle of 50.24°. Because of the nanowire array morphology, the p-Si NWs were more hydrophilic nature with a water contact angle of 3.36°, which manifests superior photocatalytic oxidative coupling. Raman spectra were conducted to confirm the surface composition of the synthesized

• p-Si NW Conclusion A p–n junction TiO2/SiNWs photocatalyst was synthesized via ALD and utilized for light-driven OCM. TiO2/SiNWs revealed excellent performance owing to the smooth transport of photogenerated electrons in the p–n junction, which lowers the e–h recombination rate. The nanowire array

Bolometric IR photoresponse based on a 3D micro-nano integrated CNT architecture

• Yasameen Al-Mafrachi,
• Sandeep Yadav,
• Sascha Preu,
• Jörg J. Schneider and
• Oktay Yilmazoglu

Beilstein J. Nanotechnol. 2024, 15, 1030–1040, doi:10.3762/bjnano.15.84

• absorption due to multiple absorption sites and can be integrated into array configurations for commercial applications. Our new designs were characterized at relatively low bias current, RT, and atmospheric pressure. It is noteworthy that the voltage responsivity of 30 V/W for sample 2 was already

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• direct sensitive recognition of various biological species. Another silicon NW-based biosensor concept was reported by Buitrago et al. [91]. This NW structure uses a vertically stacked architecture and full-depleted body channels for better array concentration. The classical top-down clean room method

• array through the gate electrode [101][102]. It has also been demonstrated that the UII MOS-based biosensor offers a higher and better sensitivity value (≈107) even in a humid environment, as compared with the classical underlap FET-biosensor for biomolecule species detection [104]. 2.2.7 Inverter and

Water-assisted purification during electron beam-induced deposition of platinum and gold

• Cristiano Glessi,
• Fabian A. Polman and
• Cornelis W. Hagen

Beilstein J. Nanotechnol. 2024, 15, 884–896, doi:10.3762/bjnano.15.73

• orientation) with a native silicon oxide layer. Samples of 1 × 1 cm2 were used, on to which an array of annular patterns was lithographically defined, by laser lithography and etching using an SF6–O2 dry-etch, to facilitate location of the deposition areas. The substrates were roughly cleaned in acetone and

• the deposition are the precursor supply, the primary beam energy and current, and the patterning strategy. The deposits are built through consecutive electron beam spot exposures of the precursor molecules adsorbed on the substrate. The shape of the deposit is defined as an area containing an array of

Green synthesis of biomass-derived carbon quantum dots for photocatalytic degradation of methylene blue

• Dalia Chávez-García,
• Mario Guzman,
• Viridiana Sanchez and
• Rubén D. Cadena-Nava

Beilstein J. Nanotechnol. 2024, 15, 755–766, doi:10.3762/bjnano.15.63

• , carbon nanomaterials exhibiting fluorescence, such as carbon oxide dots, exhibit a diverse array of structural elements, including sp2 carbon hybridization or partial hybridization commonly observed in carbon oxide dots [30][31]. The PL down-conversion spectra of the CQDs synthesized from grape pomace

Functional fibrillar interfaces: Biological hair as inspiration across scales

• Guillermo J. Amador,
• Brett Klaassen van Oorschot,
• Caiying Liao,
• Jianing Wu and
• Da Wei

Beilstein J. Nanotechnol. 2024, 15, 664–677, doi:10.3762/bjnano.15.55

• the rest of the structure is hydrophobic. The combination of these different wetting properties enables the plants to maintain a stable layer of air while underwater. The hydrophilic tips pin the water surface so that it does not penetrate the fiber array and, thus, trap an air layer directly on the

• , respectively. Protection through hairs. Schematics showing (A) an array of hairs providing thermal insulation, (B) a superhydrophobic hairy surface with self-cleaning properties, and (C) hairs defending from unwanted interactions with other organisms. The silhouettes mentioned below are from Noun Project. They

• twist.glyph (bacteria). Locomotion enhanced by hairs. Schematics showing (A) an array of hairs (or setae and spatulae) on the toe pad of a climbing gecko, (B) hairs (or setae) on the body of a burrowing earthworm for anchoring when pushing through soil, (C) hairs (or bristles) on the wing of a thrip, instead

Sidewall angle tuning in focused electron beam-induced processing

• Sangeetha Hari,
• Willem F. van Dorp,
• Johannes J. L. Mulders,
• Piet H. F. Trompenaars,
• Pieter Kruit and
• Cornelis W. Hagen

Beilstein J. Nanotechnol. 2024, 15, 447–456, doi:10.3762/bjnano.15.40

• process. In Figure 2a, a cross section of a simulated FEBID line is shown with a flat top in the middle and sidewalls described by two half Gaussian functions. It is noted here that a FEBID line is deposited as an array of partly overlapping point exposures, which leads to a structure with a flat top and

• separation of 700 nm. The height of the deposits was approximately 40 nm. An etch pattern comprising nine lines of 400 nm length was defined to etch the right sidewall of each deposit. This array was aligned such that each subsequent etch was positioned 20 nm farther away from the centre of the corresponding

• functioned as the reference. The lines were etched serially from left to right. The distance between the deposits was chosen to be larger than the range of the BSE electrons so that each deposit could be etched independently. Figure 3b shows a quick-scan top view SE image of the array after etching

Investigating ripple pattern formation and damage profiles in Si and Ge induced by 100 keV Ar⁺ ion beam: a comparative study

• Indra Sulania,
• Harpreet Sondhi,
• Tanuj Kumar,
• Sunil Ojha,
• G R Umapathy,
• Ambuj Mishra,
• Ambuj Tripathi,
• Richa Krishna,
• Devesh Kumar Avasthi and
• Yogendra Kumar Mishra

Beilstein J. Nanotechnol. 2024, 15, 367–375, doi:10.3762/bjnano.15.33

• to analyse the crystal structure and to locate interstitial atoms within the array of target atoms. The relation between yield and defect concentration was derived by Bøgh [33]. It provides information about the depth distribution of defects in the first few microns beneath the crystalline surface