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Search for "biopolymer" in Full Text gives 30 result(s) in Beilstein Journal of Nanotechnology.
Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study
Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93
- poorly water-soluble CUR. An effective submicron particle fabrication technique, namely co-precipitation–cross-linking–dissolution (CCD), has been established to produce biopolymer particles [24][25][26]. In this method, biopolymer particles are produced via co-precipitation, by simply mixing MnCl2 and
- Na2CO3 solutions in the presence of albumin [26][27]. This approach has been shown to have high effectiveness for entrapping various biopolymers (e.g., proteins and hemoglobin) into carbonate particles before dissolving with EDTA to obtain pure biopolymer submicron particles. The CCD technique is a
Nanoarchitectonics to entrap living cells in silica-based systems: encapsulations with yolk–shell and sepiolite nanomaterials
Beilstein J. Nanotechnol. 2023, 14, 522–534, doi:10.3762/bjnano.14.43
- for cancer treatment [31]. Results and Discussion Sepiolite–biopolymer microalgal biohybrids Sepiolite, a microfibrous hydrated magnesium silicate with the formula Si12O30Mg8(OH,F)4(H2O)4·8H2O [32][33][34], shows interesting surface properties and high viscosity [27][33][34][35]. These properties make
- to be tested as immobilization matrices of microalgae. Sepiolite–alginate beads, sepiolite–chitosan/alginate thin films, and sepiolite–chitosan foams were produced (Figure 1). Sepiolite and biopolymer concentration, synthesis temperature, and microorganism concentration were modified to study their
- –alginate biohybrid beads strongly limit the diffusion of metabolites, as we determined by means of diffusion studies using Congo red and crystal violet dyes (Supporting Information File 1, Figure S1). It can be concluded that the developed sepiolite–biopolymer nanostructured materials exhibit interesting
Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities
Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31
- treatment, nanoparticles have an important place to overcome the physiological limitations and to improve therapeutic efficiency [8][9]. Chitosan is a natural polysaccharide biopolymer of different molecular weights bearing amino and hydroxy functional groups [10]. It is the main component of shellfish such
Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics
Beilstein J. Nanotechnol. 2022, 13, 1393–1407, doi:10.3762/bjnano.13.115
- -/microscale systems [25]. Chitosan is a natural biopolymer that is widely used in oral nanoparticulate formulations to provide increased drug concentration in the colon and to achieve improved therapy for the colon [26][27][28]. The degradation of chitosan occurs through the lysis of glycosidic bonds by the
Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration
Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92
- modelling and clinical imaging of the scaffolds will assist in the establishment of its micro- and nanoarchitecture, which will aid in the regulation and activation of the immune system for bone tissue repair and regeneration. Conclusion Chitosan is a naturally occurring biopolymer with appropriate
Engineered titania nanomaterials in advanced clinical applications
Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15
- ]. Non-steroidal anti-inflammatory drugs (e.g., quercetin, ibuprofen, dexamethasone, aspirin, indomethacin) have been successfully loaded and eluted locally from TNTs in vitro in titania-based implants. Surface modifications such as biopolymer coating, polymeric micelle encapsulation, and periodic
Bacterial safety study of the production process of hemoglobin-based oxygen carriers
Beilstein J. Nanotechnol. 2022, 13, 114–126, doi:10.3762/bjnano.13.8
- chemically modified, cross-linked, polymerized, or encapsulated by various methods [1][2][3]. We produce biopolymer microparticles as HBOC with the simple coprecipitation–cross-linking–dissolution (CCD) technique while utilizing hemoglobin. Depending on the biopolymer used, there are also various other
- concept for the production of HbMP for the potential use as an artificial oxygen carrier and blood substitute. Conclusion In conclusion, we could show that HbMP can be safely produced with respect to bacterial contamination. Biopolymer particles can be produced with the simple CCD technique and promise a
- wide range of biomedical applications, depending on the biopolymer used. The application of HbMP as artificial oxygen carriers came into focus. Initial preclinical studies yielded promising results. In these particles (i.e., HbMP), hemoglobin is used for particle production and EDTA and glutaraldehyde
Wet-spinning of magneto-responsive helical chitosan microfibers
Beilstein J. Nanotechnol. 2020, 11, 991–999, doi:10.3762/bjnano.11.83
- polysaccharides such as alginate, hyaluronic acid or chitosan, are widely used as biocompatible materials since they are biochemically similar to the native extracellular matrix (ECM) [16]. Chitosan is a biopolymer that combines excellent biocompatibility, low toxicity and antibacterial properties with a low
Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery
Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41
- /biopolymer systems in applications such as therapeutics, biosensing, bioimaging, bioreactors, vaccination, tissue engineering and gene delivery. This review gives an emerging outlook on the advantages and unique responsiveness of weak polyelectrolyte based systems that can enable their widespread use in
Layered double hydroxide/sepiolite hybrid nanoarchitectures for the controlled release of herbicides
Beilstein J. Nanotechnol. 2019, 10, 1679–1690, doi:10.3762/bjnano.10.163
- for agricultural applications. In order to achieve a more controlled release of the herbicide and to act for several days on the surface of the soil, the hybrid nanoarchitectures were encapsulated in a biopolymer matrix of alginate/zein and shaped into spheres. In in vitro tests carried out in
- interest for agricultural purposes. Given that the amount of initial release of MCPA in all the formulations is quite high, the encapsulation of the hybrid nanoarchitectures in a protective biopolymer matrix was proposed to afford a better control over the release of the herbicide. In a previous study [49
- ], a biopolymer mixture of alginate and zein incorporating the MCPAie-LDH hybrid prepared by ion exchange was able to reduce the initial release of MCPA by approximately 10–15% in the first 8 h. In the current work, the MCPA-LDH/Sep0.5:1_60C nanoarchitecture was selected, as it releases 100% of the
Multicomponent bionanocomposites based on clay nanoarchitectures for electrochemical devices
Beilstein J. Nanotechnol. 2019, 10, 1303–1315, doi:10.3762/bjnano.10.129
- properties of the bionanocomposite materials were evaluated in stress–strain measurements (Figure S5, Supporting Information File 1), analysing the influence of the nanofiller content on the elastic behaviour as it has been described in related biopolymer-based nanocomposites [26]. The results show that the
- conferring robustness to these systems as the Young’s modulus of 0.2 MPa for a foam without chitosan (with the composition of 1:1:1:0.3 in HNTs/SEP/GNPs/MWCNTs) increases to 3.5 MPa after incorporation of the biopolymer (45 wt %). This increase can be correlated to the strong interaction between the chitosan
- the different components integrated in the bionanocomposite materials, i.e., (A) sepiolite fibrous clay, (B) halloysite nanotubes, (C) graphene nanoplatelets, (D) multiwalled carbon nanotubes, and (E) chitosan biopolymer, prepared in aqueous media under ultrasound irradiation (US). The resulting
Polydopamine-coated Au nanorods for targeted fluorescent cell imaging and photothermal therapy
Beilstein J. Nanotechnol. 2019, 10, 794–803, doi:10.3762/bjnano.10.79
- silica shells. However, PDA coating makes the functionalization with any amine-containing ligand very simple and robust. It is sufficient to incubate PDA-coated nanorods with a desired functionalization component (for example, with folate and R123). Furthermore, the biocompatibility of the PDA biopolymer
Accurate control of the covalent functionalization of single-walled carbon nanotubes for the electro-enzymatically controlled oxidation of biomolecules
Beilstein J. Nanotechnol. 2018, 9, 2750–2762, doi:10.3762/bjnano.9.257
- nicotinamide adenine dinucleotide hydride (NADH) [6][8][13][19]. The CNTs and mediator are co-deposited on the GCE using a polymer. Chitosan is often used as a cheap biodegradable biopolymer with good compatibility with CNTs for making adequate suspensions before deposition on the GCE [20]. The main problem
Nanocellulose: Recent advances and its prospects in environmental remediation
Beilstein J. Nanotechnol. 2018, 9, 2479–2498, doi:10.3762/bjnano.9.232
- -based alternatives for wastewater purification. These flocculants are expected to be degradable and prevent secondary pollution to the natural environment. Biopolymer-based flocculants such as chitosan, tannins, cellulose and alginate are attracting wide interest from many researchers. Bio-based
Electrodeposition of reduced graphene oxide with chitosan based on the coordination deposition method
Beilstein J. Nanotechnol. 2018, 9, 1200–1210, doi:10.3762/bjnano.9.111
- and good adsorption capacity [1][2].Graphene has a diverse range of applications in solar cells, hydrogen storage materials, electroluminescent devices and electrode materials [3][4][5]. In particular, graphene or reduced graphene oxide (rGO) and biopolymer (e.g., gellan gum, chitosan, and alginate
- ], the weight fraction of rGO is calculated to be 12% in the deposited HACC-rGO/CS film based on the difference between the residues of two samples at 750 °C. It has been reported that chitosan is the first biopolymer to be electrodeposited based on a cathodic neutralization mechanism which is now used
Liquid-crystalline nanoarchitectures for tissue engineering
Beilstein J. Nanotechnol. 2018, 9, 205–215, doi:10.3762/bjnano.9.22
- challenges for applying LC nanoarchitectures in tissue engineering fields is discussed. Keywords: biocolloid; biopolymer; cell-matrix interaction; mesophase; regenerative medicine; Review Introduction Liquid crystals (LCs) are ubiquitous in our life [1]. On one hand, LC materials play a central role in
- coherence within local microenvironments in vivo, similar to our native tissue function [128]. Lyotropic liquid-crystalline phase transition of a dispersion of rod-like particles as a function of rod volume fraction (i.e., rod concentration). A biopolymer (such as dsDNA, collagen, chitin and cellulose) or a
Surfactant-induced enhancement of droplet adhesion in superhydrophobic soybean (Glycine max L.) leaves
Beilstein J. Nanotechnol. 2017, 8, 2345–2356, doi:10.3762/bjnano.8.234
- tissues (shoots, leaves, fruits) of higher plants [10][11]. It is built up by a network of the cross-linked ester-like biopolymer, cutin, with integrated (intracuticular) and superimposed (epicuticular) waxes [12][13]. A large diversity of epicuticular wax chemistry and morphology has been described [14
A biofunctionalizable ink platform composed of catechol-modified chitosan and reduced graphene oxide/platinum nanocomposite
Beilstein J. Nanotechnol. 2017, 8, 1508–1514, doi:10.3762/bjnano.8.151
- . First, we prepare dispersions of reduced graphene oxide (rGO) decorated with platinum nanoparticles (rGO–Pt) in ethylene glycol (EG). As the polymer matrix, we utilize chitosan (CHI), a polycationic biopolymer that provides excellent film-forming properties and easy-to-functionalize amine groups [8
Cationic PEGylated polycaprolactone nanoparticles carrying post-operation docetaxel for glioma treatment
Beilstein J. Nanotechnol. 2017, 8, 1446–1456, doi:10.3762/bjnano.8.144
- [42], which contribute to the potential of this biopolymer for drug delivery and formulation. Although systemic application is frequently preferred for nanomedicines, local administration is a major opportunity when on-site therapy is possible and intended for. In fact, local or implantable
3D printing of mineral–polymer bone substitutes based on sodium alginate and calcium phosphate
Beilstein J. Nanotechnol. 2016, 7, 1794–1799, doi:10.3762/bjnano.7.172
- calcium phosphate (CP) for bone tissue engineering. The fabrication of 3D composite structures was performed through the synthesis of inorganic particles within a biopolymer macromolecular network during 3D printing process. The formation of a new CP phase was studied through X-ray diffraction, Fourier
- according to the following reaction: In fact, the mixture of the phosphate source with alginate gives rise to a homogeneous gel, suggesting an interaction between the biopolymer and the HPO42−. The stability and homogeneity of this gel can be explained by possible interactions between the HPO42− moiety and
Effective intercalation of zein into Na-montmorillonite: role of the protein components and use of the developed biointerfaces
Beilstein J. Nanotechnol. 2016, 7, 1772–1782, doi:10.3762/bjnano.7.170
- of zein intercalation, the structure and features of the synthesized biohybrids were also analyzed. Zein-based biohybrids were further tested as reinforcing fillers of other biopolymer matrixes to probe their usefulness in the development of “fully” ecofriendly bioplastics. In fact, organoclays
- explain the ability of the hydrophobic protein to penetrate into the interlayer region of sodium montmorillonite following the “synthesis 2” approach proposed in this work. Zein-layered clays as nanofillers in biopolymer films The biocompatible character of the developed bio-organoclays makes them an
- biopolymer films were prepared by casting methods (Figure 7). For this it is necessary to add a certain amount of glycerol as plasticizer component in the blank films to reduce their high brittleness. The light transmittance of zein bionanocomposites was higher for films containing Z-MMT_S2, but in the
Counterion effects on nano-confined metal–drug–DNA complexes
Beilstein J. Nanotechnol. 2016, 7, 62–67, doi:10.3762/bjnano.7.7
- –DNA composites; polyelectrolyte; X-ray scattering; Introduction Condensed state behaviour of DNA, the best-known biopolymer, in a confined space is a matter of interest due to its relevance in living systems. Within cells DNA molecules remain in a confined space crowded by other molecules and ions
Green and energy-efficient methods for the production of metallic nanoparticles
Beilstein J. Nanotechnol. 2015, 6, 2354–2376, doi:10.3762/bjnano.6.243
- the microwave power from 30 to 120 W can reduce the heating time and particle size from 23 to 28 nm [112]. Kora et al. synthesized Ag NPs from AgNO3 in an autoclave at 120 °C and 15 psi. In their reaction, gum kondagogu (Cochlospermum gossypium), a natural biopolymer with several hydroxyl and
Fabrication of hybrid nanocomposite scaffolds by incorporating ligand-free hydroxyapatite nanoparticles into biodegradable polymer scaffolds and release studies
Beilstein J. Nanotechnol. 2015, 6, 2217–2223, doi:10.3762/bjnano.6.227
- biopolymer, a biodegradable and photocurable material. The photocrosslinking efficiency is usually adjusted by the added photoinitiator (PI) concentration („chemical tuning”), though we recently demonstrated that great stiffness tuning (over four orders of magnitude) could be achieved by changing various
Biopolymer colloids for controlling and templating inorganic synthesis
Beilstein J. Nanotechnol. 2014, 5, 2129–2138, doi:10.3762/bjnano.5.222
- Laura C. Preiss Katharina Landfester Rafael Munoz-Espi Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany 10.3762/bjnano.5.222 Abstract Biopolymers and biopolymer colloids can act as controlling agents and templates not only in many processes in nature, but also in a
- wide range of synthetic approaches. Inorganic materials can be either synthesized ex situ and later incorporated into a biopolymer structuring matrix or grown in situ in the presence of biopolymers. In this review, we focus mainly on the latter case and distinguish between the following possibilities
- , micelles, and vesicles, and on the other hand continuous scaffolds generated by gelling biopolymers. Keywords: biomacromolecules; biopolymer; colloid; nanoparticle; organic–inorganic hybrid; template; Introduction During the natural synthesis of inorganic matter in living organisms, referred to as
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