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Search for "hydrophobic" in Full Text gives 360 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.
Fabrication of nanocrystal forms of ᴅ-cycloserine and their application for transdermal and enteric drug delivery systems
Beilstein J. Nanotechnol. 2024, 15, 465–474, doi:10.3762/bjnano.15.42
- detection was accomplished with a LYNXEYE detector (Bruker AXS GmbH), and the XRPD patterns were obtained on a D8 ADVANCE (Bruker AXS GmbH). Preparation of different hydrophobic formulations mixed with DCS aqueous solution for the reservoir transdermal delivery The DCS aqueous solution was mixed with
- different hydrophobic solutions to obtain emulsion solutions, and loaded into the donor compartment of the Franz diffusion cell for 24 h. The release of DCS was detected in the receptor compartment. The summary of DCS formulations and release is shown in Table 1 and described as: Formulation Test 1: 20 mg
- : where DCSfinal and DCSinitial represent the final and initial amounts of DCS, respectively. Preparation of DCS nanocrystals and commercial DCS powder loaded with different hydrophobic formulations for the reservoir transdermal delivery The DCS nanocrystals as well as commercial DCS powder (Stride Pharma
Multiscale modelling of biomolecular corona formation on metallic surfaces
Beilstein J. Nanotechnol. 2024, 15, 215–229, doi:10.3762/bjnano.15.21
- HIE, GLN, PHE, GAN (−43.86kBT to −20.85kBT). VAL, THR, SER, CYS, ALA exhibit the weakest attraction (−19.51kBT to −1.76kBT). On iron surfaces, charged and aromatic PRO, TYR, ARG, HIS AAs are strongly adsorbed (−91.29kBT to −43.34kBT), while hydrophobic VAL, LEU, ALA AAs show a weaker adhesion
Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics
Beilstein J. Nanotechnol. 2024, 15, 180–189, doi:10.3762/bjnano.15.17
- particle [25][26]. PLGA is one of the finest materials for transporting chemotherapy drugs. PLGA transports not only hydrophobic but also hydrophilic drugs. The encapsulation of chemotherapeutics in PLGA nanoparticles has been extensively studied. PLGA has been loaded with doxorubicin, for instance, for
- when incubated with PVA@PLGA nanoparticles [31]. Their research yielded similar findings to our own results. First, F127 could briefly switch the ligand between PVA and F127, or F127 PPO block could stick to the hydrophobic outer shell of PLGA nanoparticles. The presence of F127 on PLGA@NP decreases
Modification of graphene oxide and its effect on properties of natural rubber/graphene oxide nanocomposites
Beilstein J. Nanotechnol. 2024, 15, 168–179, doi:10.3762/bjnano.15.16
- grafting GO onto DPNR. The results show that the tensile strength of DPNR/GO increased compared to that of DPNR, which proved the successful grafting of GO onto NR by the radical route. However, GO possesses a highly hydrophilic character, which is the opposite of the highly hydrophobic nature of NR. Thus
Study of the reusability and stability of nylon nanofibres as an antibody immobilisation surface
Beilstein J. Nanotechnol. 2024, 15, 83–94, doi:10.3762/bjnano.15.8
- the antibody by hydrophobic interactions through binding sites inside of its three-dimensional structure [21][22]. The polar side chains are located on the outside of the protein molecule, allowing the protein to form hydrogen bonds with nylon. On the other hand, nylon is a polyamide that contains
- of hydrophobic interactions [21][22]. Acidic pH values below 5 cause protein A/G to separate from antibody, probably by imposing positive charges on amino acids with pKa values above 5, such as histidine, as described in Zarrineh et al. for the interaction between protein A and the Fc of antibody [25
- an environment of high ion concentration capable of interacting with any charge density group, disrupting the hydrophobic bonds between protein A/G and antibody and the hydrogen bonds between protein A/G and nylon, as well as the bare nylon nanofibres. Results of stability study As this system is
Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency
Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7
- Sciences, Phenikaa University, Hanoi 12116, Vietnam 10.3762/bjnano.15.7 Abstract Hydrophobic berberine powder (BBR) and hydrophilic BBR nanoparticles (BBR NPs) were loaded into an electrospun polylactic acid (PLA) nanofiber scaffold for modulating the release behavior of BBR in an aqueous medium. The BBR
- BBR/PLA nanofiber scaffold exhibited an extremely hydrophobic feature, causing a triphasic release profile in which only 9.8 wt % of the loaded BBR was released in the first 24 h. This resulted in a negligible inhibitory effect against methicillin-resistant Staphylococcus aureus bacteria. Meanwhile
- nanofiber compositions [11][12][13]. For a long-term drug release, hydrophobic polymers are chosen for the preparation of drug-loaded nanofiber scaffolds. This is because the hydrophobicity of the polymer could form air gaps, slowing matrix hydration and suppressing drug diffusion from the nanofibers [14
Influence of conductive carbon and MnCo2O4 on morphological and electrical properties of hydrogels for electrochemical energy conversion
Beilstein J. Nanotechnol. 2024, 15, 57–70, doi:10.3762/bjnano.15.6
- ][2][3]. The methods of synthesising hydrogels are divided into two basic groups, including physical and chemical cross-linking. Physical cross-linking methods, which are mainly related to the synthesis of natural hydrogels, include changes in intermolecular interactions (e.g., hydrophobic
Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review
Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4
- , the intracellular uptake of bioactive molecules is especially hindered for hydrophobic molecules [64], making it difficult for the drug to reach the parasite. On the other hand, nanocarriers can target the interior of macrophages residing in the spleen, liver, and bone marrow, effectively delivering
Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment
Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96
- hydrophilic, O2 plasma-treated substrates [21]. We measured the water contact angle (CA) on the PU samples (Figure 1I) and found that all of the as-fabricated samples were hydrophobic (CA > 90°), with the nanostructured substrates being more so. Since the CA for flat PU indicates a hydrophobic surface, the
Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study
Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93
- hydrophobic yellow-orange polyphenol compound isolated from the rhizomes of Curcuma longa. Numerous studies have consistently demonstrated that CUR displays a vast range of pharmacological and medicinal properties, including antioxidant, anti-inflammatory, anti-diabetic, anti-hepatotoxic activities, and
- stability and solubility [9]. The complexation occurs mainly through hydrophobic interactions in protein cavities [10][11]. In a recent study, zein nanoparticles loaded with CUR have been studied for their potential in treating brain tumors, and the results have demonstrated a reduction in the proliferation
- , which is a common process in the preparation of nanoparticle formulations, also causes them to agglomerate due to their hydrophobic properties [16]. In the case of silk nanoparticles, the addition of simple functional groups has provided a limited range of options for chemical modification [17]. In
Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics
Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75
- , which includes physical adsorption and electrostatic binding (Figure 3) [38]. Physical adsorption consists of either non-covalent weak hydrophobic or electrostatic hydrogen bonding, or attractive van der Waals interaction between antibodies and NPs [39]. Ionic binding, in contrast, involves an
- demonstrated that no additional steps for conjugation were required, such as antibody modification or NP surface group activation. However, there are several drawbacks of this method. The method is the least stable and requires high concentrations of antibodies for adsorption. Hydrophobic interaction can also
Biomimetics on the micro- and nanoscale – The 25th anniversary of the lotus effect
Beilstein J. Nanotechnol. 2023, 14, 850–856, doi:10.3762/bjnano.14.69
- dehumidifiers or water purifiers. The authors here present a model based on a carbon nanotube structure that might finally provide a route to the breakthrough in this field. Their archetype, the Namibian desert beetle, uses a geometric separation of hydrophilic and hydrophobic regions to harvest and drive water
Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review
Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52
- redox reaction during the electron deactivation process. For effective quenching, a complex driven by either hydrophobic, van der Waals, or π–π-stacking interactions is generated between the electron donor and the electron acceptor with a separation on a sub-nanometre length scale. The complexation of
Conjugated photothermal materials and structure design for solar steam generation
Beilstein J. Nanotechnol. 2023, 14, 454–466, doi:10.3762/bjnano.14.36
- absorbers. Half of the surface consists of hydrophilic groups and the other half is hydrophobic groups. Through capillary action, the hydrophilic section sequentially supplies water to the evaporation region, while the hydrophobic segment regulates the surplus water that leads to heat loss in the bulk water
- applied on top of the PS insulator without the need for an additional water transport layer. Membranes Janus structural membranes with hydrophilic and hydrophobic surfaces are key structures for highly efficient SSGs. Such Janus membranes can be easily produced by filtering or coating hydrophilic
- membranes with hydrophobic photothermal material particles. Over the past years, various types of SSG membranes have been studied [37][39][45][54][56][57]. These SSG membranes can be applied to, for example, seawater desalination and photocatalytic degradation by utilizing the photothermal and separation
Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science
Beilstein J. Nanotechnol. 2023, 14, 434–453, doi:10.3762/bjnano.14.35
- water impermeability of the bilayer membrane causes one-dimensional swelling and diffusion, and the hydrophobic aggregates act as sacrificial bonds to yield high mechanical strength and toughness during deformation. The abovementioned general examples could be involved in parts of nanoarchitectonics
Polymer nanoparticles from low-energy nanoemulsions for biomedical applications
Beilstein J. Nanotechnol. 2023, 14, 339–350, doi:10.3762/bjnano.14.29
- . Nanoemulsions can be formulated to contain oily (hydrophobic) droplets in a continuous aqueous phase, that is, as in oil-in-water (O/W) nanoemulsions or aqueous droplets in a continuous oily (hydrophobic) phase as in water-in-oil (W/O) nanoemulsions. To form an emulsion, the liquid to be dispersed should be
- emulsification processes that involve phase inversion are based on the phase inversion temperature (PIT) or the phase inversion composition (PIC). The PIT method [6][7][8] applies to nonionic ethoxylated surfactants that change from water-soluble (hydrophilic) to oil-soluble (hydrophobic) with increasing
- roughly estimated by [18]: where Ms is the surfactant molecular weight, as is the area occupied per surfactant molecule at the O/W interface, NA is Avogadro’s number, ρ0 is the density of the oil phase, Ros is the oil/surfactant mass ratio, and vL is the molar volume of the hydrophobic part of the
Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer
Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23
- of molecularly targeted drugs, chemotherapeutic agents, and siRNA. Historically, the most promising first-generation, passive targeting, stealth polymer NPs for anticancer drug/gene delivery are hydrophobic core–hydrophilic shell NPs including (i) self-assembled kinetically stable amphiphilic block
- the lysosomes, exposing the PDMAEMA layer decorated with triphenylphosphonium (TPP) ligand to the environment. The TPP lipophilic cation is characterized by a large hydrophobic surface area, which facilitates its permeation throughout phospholipid bilayers, lysosomal escape due to the proton sponge
- physicochemical properties (polar headgroup, linker region, and type and length of hydrophobic domain), PEG amount, PEG lipid alkyl length, as well as the physicochemical properties of the LNPs (zeta potential, pKa value, and structure and conformation of the lipid bilayer) will result in improved targeting
Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems
Beilstein J. Nanotechnol. 2023, 14, 218–232, doi:10.3762/bjnano.14.21
- photocatalytic process destroy subcellular structures (e.g., cell membranes or organelle membranes). Various types of cancers are effectively treatable without significant side effects. However, most photosensitizers available at present are hydrophobic and easily aggregate in aqueous solution. Thus, the
- enhances the hydrophobic interactions of the poly(N-isopropylacrylamide) segments, stabilizing the hydrogel. The anticancer drug DOX encapsulated in the hydrophobic core is slowly released through the dissolution of the hydrogel to micelles. By modifying β-CyD with both N-acetyl-ʟ-cysteine and arginine
Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine
Beilstein J. Nanotechnol. 2023, 14, 165–174, doi:10.3762/bjnano.14.17
- oxygen or any other reactive oxygen species. In our previous works, we used polyoxyethylene−polyoxypropylene−polyoxyethylene Pluronic 68 (PF68) as precursor to synthesize hydrophobic CQDs [18][19]. These quantum dots produce high levels of singlet oxygen, and their chemical composition differs from that
- composites has a crucial effect on the properties of CQDs/PU composites. Cellular uptake Photobleaching limits the use of hydrophobic probes (e.g., Nile red) [50]. CQDs can be used as probes for bioimaging because of the tuneable strong photoluminescence and high resistance to photobleaching. In order to
- 12 h at 180 °C. All chemicals were purchased and used as received. After synthesis, CQDs were filtered through polytetrafluoroethylene (PTFE) filters with 100 nm pore size. The prepared hydrophobic CQDs (toluene solution, 20 mL) were encapsulated into medical grade polyurethane (PU) films (dimension
Solvent-induced assembly of mono- and divalent silica nanoparticles
Beilstein J. Nanotechnol. 2023, 14, 52–60, doi:10.3762/bjnano.14.6
- with two patches functionalized with metal-coordination-based recognition units [20], and by co-assembly of block copolymer micelles and hard nanoparticles [21]. Particles with two patches located at opposite poles have been assembled into a Kagome lattice by hydrophobic interactions [22], into chains
- by liquid bridging [23], and into a series of structures under an AC electric field [24]. The linear self-assembly of patchy gold nanorods tethered with hydrophobic polymer chains at both ends can be triggered by solvophobic attractions induced by a change in solvent quality [25]. By using post
Atmospheric water harvesting using functionalized carbon nanocones
Beilstein J. Nanotechnol. 2023, 14, 1–10, doi:10.3762/bjnano.14.1
- [17]. This beetle has hydrophilic spots on its back, which transform vapor into liquid water. For the collection to be efficient, below the hydrophilic spots, its wings are hydrophobic, and the captured water moves from hydrophilic to hydrophobic parts driven by gravity. The efficiency of this process
- led to the development of mimetic strategies [18][19][20][21], which require the combination of wetting and dewetting properties used by the beetle. The hydrophobic region, as is also the case for the cactus, is fundamental for the mobility of water. Water presents other kinds of anomalous behavior in
- slowing down when confined in biological structures with the presence of hydrophobic and hydrophilic sites [25]. Water confined in hydrophobic structures, such as carbon nanotubes with diameters below 2 nm, exhibits a fast flow that exceeds values provided by classical hydrodynamics [26]. This super flow
Single-step extraction of small-diameter single-walled carbon nanotubes in the presence of riboflavin
Beilstein J. Nanotechnol. 2022, 13, 1564–1571, doi:10.3762/bjnano.13.130
- carbon nanotube geometries remain one of the paramount technological challenges for their potential applications [2][5][8][9][10]. The noncovalent functionalization of carbon nanotubes promotes their individualization due to hydrophobic interactions between nanotubes and surfactant molecules that also
- -step gel filtration. We found that the riboflavin molecules are selectively adsorbed on small-diameter semiconducting SWCNTs facilitating specific hydrophobic interactions between the nanotubes and gel extraction media consistent with first-principles calculations. Results and Discussion Riboflavin as
Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy
Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118
- are hydrophobic PTAs with rigid structure and poor water solubility [11][12]. Therefore, several lipid nanoparticulate drug delivery systems have been reported to encapsulate BODIPYs to improve their water solubility and photostability while retaining their original photothermal effects [13][14
- delivery systems through van der Waals forces, hydrogen bonds, π–π stacking, or electrostatic or hydrophobic interactions [24]. Several BODIPYs have been reported to be loaded into liposomes for cancer therapy [25]. Therefore, we speculated that BODIPY can be associated with our previously reported
- in H2O. The binding of hydrophobic BDP onto Au-LNPs might affect the light absorption of Au nanoclusters. The loading efficiency of BDP in AB-LNPs determined by using UV–vis measurements (λex = 600 nm) is 51 ± 1.2% (n = 3). A TEM image of AB-LNPs is shown in Figure 1c. Particles with diameters of ca
Dry under water: air retaining properties of large-scale elastomer foils covered with mushroom-shaped surface microstructures
Beilstein J. Nanotechnol. 2022, 13, 1370–1379, doi:10.3762/bjnano.13.113
- superhydrophobic surfaces and self-cleaning properties are available on the market [1][6][7]. A most interesting feature of certain superhydrophobic surfaces is their ability to maintain a persistent air layer submerged under water. This ability is called Salvinia effect [5][8][9][10]. Due to the hydrophobic
Straight roads into nowhere – obvious and not-so-obvious biological models for ferrophobic surfaces
Beilstein J. Nanotechnol. 2022, 13, 1345–1360, doi:10.3762/bjnano.13.111
- via hierarchically organised hydrophobic surface structures when forced under water [3][21][22]. There are three levels of protection against wetting in Collembola: (i) a hairy cover consisting of bristles with water pinned to the tips (Figure 3a), (ii) nanoscopic hexagonal or rhombic comb structures
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