Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

• the ECM [50]. The most important adhesion proteins produced by numerous bacteria and virus particles involve surface lectins, known as adhesins and hemagglutinins, that bind to complimentary tissue-specific host cell-surface glycoproteins and glycolipids [82]. Blocking these bacterial lectins by their

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

• Maria Suciu,
• Corina M. Ionescu,
• Alexandra Ciorita,
• Septimiu C. Tripon,
• Dragos Nica,
• Hani Al-Salami and
• Lucian Barbu-Tudoran

Beilstein J. Nanotechnol. 2020, 11, 1092–1109, doi:10.3762/bjnano.11.94

• histidine–proline-rich glycoprotein, kininogen, prekallikrein, mannose-binding lectins, complement factors, clotting factors, immunoglobulins, fibronectin, and fibrinogen. They obtained the equivalent of 1 mg of proteins bound to 1 mg of iron oxide (in the case of extensive washing). This corona of proteins

Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials

• Stefania Ordanini,
• Wanda Celentano,
• Anna Bernardi and
• Francesco Cellesi

Beilstein J. Nanotechnol. 2019, 10, 2192–2206, doi:10.3762/bjnano.10.212

• polymerizations provided high control over molecular weight and functionality. A post-polymerization azide–alkyne cycloaddition allowed for the formation of glycopolymers with different mannose valencies (1, 2, 4, and 8). In aqueous media, these macromolecules formed nanoparticles that were able to bind lectins

• saccharide–protein connections. Carbohydrate-binding proteins are known as lectins. A way to interfere with pathological carbohydrate–protein interactions is the use of artificial ligands able to antagonize lectins, possibly with higher affinity than the natural ligands. Multivalent glycoconjugates have been

• important and well-studied class of synthetic glycoclusters [6]. They have the advantage of being easy to synthesize and present larger valencies with respect to other multivalent compounds, thus exhibiting an amplified binding potency towards lectins. In some cases, glycopolymers have shown affinities for

The structural and chemical basis of temporary adhesion in the sea star Asterina gibbosa

• Birgit Lengerer,
• Marie Bonneel,
• Mathilde Lefevre,
• Elise Hennebert,
• Philippe Leclère,
• Emmanuel Gosselin,
• Peter Ladurner and
• Patrick Flammang

Beilstein J. Nanotechnol. 2018, 9, 2071–2086, doi:10.3762/bjnano.9.196

• tested 24 commercially available lectins and two antibodies for their ability to label the adhesive epidermis and footprints. Out of 15 lectins labelling structures in the area of the duo-gland adhesive system, only one also labelled footprints indicating the presence of glycoconjugates with α-linked

• adhesion and might facilitate the development of biomimetic, reversible glues. Keywords: duo-gland adhesive system; lectins; marine temporary adhesion; starfish; Introduction Marine biological adhesives are environmentally friendly, biodegradable, and adhere to various surfaces in the challenging

• available lectins on tube foot sections and footprints. Results and Discussion The starlet cushion star, Asterina gibbosa, is a small sea star inhabiting wide areas in the northeast Atlantic Ocean and the Mediterranean Sea (Figure 1A). Being an exclusively benthic animal, it relies on the strong and

Probing fibronectin–antibody interactions using AFM force spectroscopy and lateral force microscopy

• Andrzej J. Kulik,
• Małgorzata Lekka,
• Kyumin Lee,
• Grazyna Pyka-Fościak and
• Wieslaw Nowak

Beilstein J. Nanotechnol. 2015, 6, 1164–1175, doi:10.3762/bjnano.6.118

• between a glycoprotein-functionalized AFM probe and a surface modified with lectins were investigated. Such measurements were possible under the assumption that specific forces strongly dominate over non-specific (friction) forces. Moreover, the lack of a reliable and accurate calibration method precluded