Exploring the relationships between physiochemical properties of nanoparticles and cell damage to combat cancer growth using simple periodic table-based descriptors

• Joyita Roy and
• Kunal Roy

Beilstein J. Nanotechnol. 2024, 15, 297–309, doi:10.3762/bjnano.15.27

• toxicity. Furthermore, it is a well-established fact that each metal has an affinity constant for various ligands, which means that most metal cations can form stable complexes with a wide variety of ligands, further increasing their potential toxicity. In the field of physical chemistry, the zeta

Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics

• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan-Thang Cao,
• Vy Tran-Anh and
• Hieu Vu Quang

Beilstein J. Nanotechnol. 2024, 15, 180–189, doi:10.3762/bjnano.15.17

• oxide) (PEO). To improve the targeting ability of nanoparticles, ligands are typically designed to be located on the exterior of nanoparticles. Typically, ligands are cell-type-specific monoclonal antibodies, RGD peptides for the overexpression of the asialoglycoprotein receptor on cancer cells [5

• our NPs. Second, the ligand attached to the nanoparticles would aid in the accumulation of nanoparticles within the cells. Numerous studies have employed different ligands to target overexpressed receptors on cancer cells, including folate receptors [13][37], integrins [36][37], and vascular

CdSe/ZnS quantum dots as a booster in the active layer of distributed ternary organic photovoltaics

• Gabriela Lewińska,
• Piotr Jeleń,
• Zofia Kucia,
• Maciej Sitarz,
• Łukasz Walczak,
• Bartłomiej Szafraniak,
• Jerzy Sanetra and
• Konstanty W. Marszalek

Beilstein J. Nanotechnol. 2024, 15, 144–156, doi:10.3762/bjnano.15.14

• outstanding excitation and optimum charge transport in the mixture. Small-molecule materials, dyes, polymers, fullerenes, and ligands have been introduced as a third component so far. Quantum dots (QDs) are also beneficial materials for ternary solar cells. QDs and nanoparticles as zero-dimensional materials

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• ]. Nanomaterials have improved the ability to detect pathogens in water and food by enhancing signals and sensitivity. These materials, which encompass nanoparticles, nanorods, nanowires, and nanoclusters, can be combined with aptamers, antibodies, enzymes, and other ligands to display unique physical, chemical

A combined gas-phase dissociative ionization, dissociative electron attachment and deposition study on the potential FEBID precursor [Au(CH₃)₂Cl]₂

• Elif Bilgilisoy,
• Ali Kamali,
• Thomas Xaver Gentner,
• Gerd Ballmann,
• Sjoerd Harder,
• Hans-Peter Steinrück,
• Hubertus Marbach and
• Oddur Ingólfsson

Beilstein J. Nanotechnol. 2023, 14, 1178–1199, doi:10.3762/bjnano.14.98

• structures, these precursor molecules are commonly organometallics that adsorb on the substrate and are decomposed by the electron beam irradiation. Ideally, a pure metal is deposited while fragmented volatile ligands are pumped away [11][12][13]. Several parameters affect the FEBID process, including the

• -vacuum (UHV) surface science studies and mass spectrometry in high-vacuum (HV) gas-phase investigations [27][28]. In this context, surface science experiments allow for electron-dose-dependent studies of the elemental composition of the deposit, and desorbing ligands may be monitored by means of mass

• as well as deposition [22][43]. In these studies, the release of halogen ligands was indicated as the main reason for the etching process. FEBID on thermally cleaned Si(111) In several UHV-FEBID studies [43][44][45] it has been shown that an UHV setup alone is not sufficient to produce FEBID

Properties of tin oxide films grown by atomic layer deposition from tin tetraiodide and ozone

• Kristjan Kalam,
• Peeter Ritslaid,
• Tanel Käämbre,
• Aile Tamm and
• Kaupo Kukli

Beilstein J. Nanotechnol. 2023, 14, 1085–1092, doi:10.3762/bjnano.14.89

• hybridised with ligand Sn 5s states, while the three consecutive peaks at approximately 536.3, 537.7, and 539.6 eV correspond to states hybridised with Sn 5p states [37][38]. In the SnO2 rutile structure, the latter states are non-degenerate because of non-equidistant ligands for the axes of the coordination

Dual-heterodyne Kelvin probe force microscopy

• Benjamin Grévin,
• Fatima Husainy,
• Dmitry Aldakov and
• Cyril Aumaître

Beilstein J. Nanotechnol. 2023, 14, 1068–1084, doi:10.3762/bjnano.14.88

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one

• Jonathan-Gabriel Nimz,
• Pichayut Rerkshanandana,
• Chiraphat Kloypan,
• Ulrich Kalus,
• Saranya Chaiwaree,
• Axel Pruß,
• Radostina Georgieva,
• Yu Xiong and
• Hans Bäumler

Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85

• a long list of ligands including modified serum albumin, which might also occur within our HBMPs [36]. The interaction of HbMPs (with different surface modifications) with Hp, as well as with anti-Hb antibodies has already been studied by Prapan and co-workers [19]. With this work, the investigation

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• materials, such as Fe3O4@Cu2−xS, the photothermal properties can also be changed [44]. In addition, because of the high surface-to-volume ratio and highly functional surface ligands, the material can be easily conjugated with a wide variety of biomolecules on its surface, which is useful in applications

Fragmentation of metal(II) bis(acetylacetonate) complexes induced by slow electrons

• Janina Kopyra and
• Hassan Abdoul-Carime

Beilstein J. Nanotechnol. 2023, 14, 980–987, doi:10.3762/bjnano.14.81

• planar to the tetrahedral configuration [25]. This change of geometry has been calculated for CuL2, for which one of the ligands rotates by 90° from the planar configuration [15]. Note that the planar anion may also co-exist, but this configuration is unstable [15]. Surprisingly from the DFT calculations

• experiments below the decomposition temperatures of the material, ML3, in which the metal is coordinated by three ligands [26][27], may also be produced at least to a small extent at the studied temperatures. Indeed, it has been observed that thermal desorption of solid thymine produces not only the monomer

• ]. As shown in Table 1, the fragmentation of the transient [ML2]#− anion results in a wide variety of negatively charged species. They arise from the decomposition of one of the ligands into X species, whereas the second ligand still binds to the metal, for example, [MLX]. The loss of C3H3 from one of

Metal-organic framework-based nanomaterials for CO₂ storage: A review

• Ha Huu Do,
• Iqra Rabani and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 964–970, doi:10.3762/bjnano.14.79

• manipulation of pore size by modifying the size of the ligands is an effective approach for accelerating CO2 adsorption. For instance, Yao et al. used different ligands to fabricate various Zn-based MOF nanomaterials with distinct pore volumes for CO2 adsorption applications [31]. Notably, SUMOF-2

Low temperature atomic layer deposition of cobalt using dicobalt hexacarbonyl-1-heptyne as precursor

• Mathias Franz,
• Mahnaz Safian Jouzdani,
• Lysann Kaßner,
• Marcus Daniel,
• Frank Stahr and
• Stefan E. Schulz

Beilstein J. Nanotechnol. 2023, 14, 951–963, doi:10.3762/bjnano.14.78

• consists of a weak CO feature and a dominant CHx part. These results show that a temperature of 35 °C does not provide sufficient thermal energy. In consequence, the precursor ligands are removed only to a minor extent. The different films prepared in the determined ALD window from 50 to 110 °C exhibit

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• active targeting via the functionalization of ligands, such as antibodies or proteins, that interact with receptors overexpressed at the target site [5][6]. However, the movement of NPs is hampered by biological barriers such as endothelial, cellular, skin, and mucosal barriers, which obstruct their

• antibodies (mAbs), and nucleic acid-based materials for targeted drug delivery, have been approved by the Food and Drug Administration (FDA) for the treatment of cancer, arthritis, asthma, psoriasis, pemphigus vulgaris, and chronic urticaria [8]. Antibodies are the primary homing ligands in tumor-targeted

• -conjugated NPs The high surface-to-volume ratio of NPs offers the advantage to manipulate their dimensions and functionalize their surface with multivalent targeting moieties to facilitate targeted delivery in tumor cells [72]. NPs are known to allow multiple ligands to bind on their surface. Multivalent

Ni, Co, Zn, and Cu metal-organic framework-based nanomaterials for electrochemical reduction of CO₂: A review

• Ha Huu Do and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 904–911, doi:10.3762/bjnano.14.74

• electrochemical reduction of CO2 into CO, with an FE of 65%. The research group also revealed that the Zn2+ species operate as active sites in the catalytic process. Another investigation shed light on the significance of organic ligands within Zn-based MOF architectures for CO2RR. Jiang et al. prepared four Zn

• -based ZIFs, including ZIF-7, ZIF-108, ZIF-8, and SIM-1, employing various ligands while utilizing the same Zn-containing salt [43]. These architectures were evaluated under identical conditions to determine the role of ligands in CO2 conversion. The ZIF-8 variant with the 2-methylimidazole ligand

N-Heterocyclic carbene-based gold etchants

• Robert B. Chevalier,
• Justin Pantano,
• Matthew K. Kiesewetter and
• Jason R. Dwyer

Beilstein J. Nanotechnol. 2023, 14, 865–871, doi:10.3762/bjnano.14.71

• ]. More recently, however, there has been an important and active effort to develop new organic ligands that support noble metal dissolution or extraction in more environmentally benign ways [28][29][30]. We present here a number of single-solute gold etchants where etching performance can be tuned by

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• within the rhizosphere [12][13]. Colloid stability of nanoceria is affected by temperature, pH, surface structure, surface-adsorbed organic and inorganic ligands, and metal/nonmetal ions and their concentrations in the solution surrounding the particles [14]. Nanoceria interacts with soil and plant roots

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• fluorophore ligands, which accounts for the excellent quenching effects of PET on the luminescence of the MOF sensor [54]. Photoinduced charge transfer (PCT): The PCT mechanism relies on the exchange of electrons between acceptor (analyte) and the donor (fluorophore), which results in the alteration of the

• biomolecules via electrostatic forces, stacking, and/or hydrogen bonding, which lead to high accumulation of the target analyte, are another factor that supports the development of electrochemical sensors. However, because of the high proportion of organic ligands, most MOFs have poor electrical conductivity

• clusters and organic ligands (i.e., “linkers” or “struts”) through coordination bonding [30][67][76][77][78]. The development of the first MOF and covalent organic framework (COF) is credited to Omar Yaghi of Berkeley University of California. In particular, Yaghi reported in 1995 on the synthesis and

Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2023, 14, 434–453, doi:10.3762/bjnano.14.35

• expression through nanoarchitectonics. Shi and co-workers created nanoparticle surfactants at liquid–liquid interfaces by exploiting the interaction between nanoparticles and polymer ligands [101]. They showed that a size-dependent aggregation of nanoparticle surfactants can be generated at the interface

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles

• Magdalena Lasak and
• Karol Ciepluch

Beilstein J. Nanotechnol. 2023, 14, 329–338, doi:10.3762/bjnano.14.28

• achievable utilizing NPs less than 100 nm in diameter. In contrast, active targeting strategies involve functionalizing the NP surface with appropriate ligands specific for receptors overexpressed by the cancer cells (e.g., folic acid and transferrin). The combination of the paracellular gap size resulting

• their various applications. NPs are characterized by a high surface-to-volume ratio, which in turn leads to a large functional surface area. The possibility of combining NPs with various ligands and biologically active molecules, such as nucleic acids, fluorescence dyes, drugs, tumor markers, and

Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

• delivery. Homotypic cancer cell membrane-modified NPs show stronger targeting capabilities than NPs modified with single ligands [20]. This is attributed to the multiple membrane receptors expressed on cancer cell membranes and their ability to avoid the formation of protein coronas [8][20]. Therefore

• intricate membrane protein components of cancer cell membranes play an important role in immune regulation. Researchers have found a number of immune checkpoint signals in cancers that could confer strong immunosuppression on cancer cells by combining ligands with inhibitory immunoreceptors, such as PD-1

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

• copolymer core–shell NPs, (ii) polymer–polypeptide hybrid core–shell NPs, and (iii) polymer–lipid hybrid core–shell NPs additionally decorated with ligands for overexpressed receptors on cancer cells [92]. Traditionally selected overexpressed cancer cell surface markers for the active targeting of NPs

• can be subsequently modified using thiolene chemistry to introduce positive charges [−NH2 (cysteamine, ENT)], negative charges [−COOH (3-mercaptopropionic acid, ECT)], and active targeting ligands [thiogalactose residues (EGT)] for fine-tuning the charges in the shell in different biological

• targeting. Once in the lung microcirculation, the RBC-bound NPs are mechanically detached from the RBCs when the RBCs are squeezed through the tiny capillaries of the air–blood barrier and transferred to the endothelium by nonspecific interactions. When decorated with vascular endothelium-specific ligands

Two-step single-reactor synthesis of oleic acid- or undecylenic acid-stabilized magnetic nanoparticles by thermal decomposition

• Mykhailo Nahorniak,
• Pamela Pasetto,
• Jean-Marc Greneche,
• Volodymyr Samaryk,
• Sandy Auguste,
• Anthony Rousseau,
• Nataliya Nosova and
• Serhii Varvarenko

Beilstein J. Nanotechnol. 2023, 14, 11–22, doi:10.3762/bjnano.14.2

• sediments was observed. According to the developed method, the formation of NPM has several stages. At the first stage of the synthesis, the change of ligands into Fe(III) acetylacetonate occurs. In the presence of higher carboxylic acids, such as oleic acid or undecylenic acid, Fe(III) alkanoate is a

• removal of acetylacetonate ligands, the reaction mixture that undergoes thermolysis contains mixed ligands. The thermal decomposition of such salts at the second stage can significantly affect the processes of particle nucleation, composition, and morphology [26][27]. To estimate the completeness of

• 200 > ∆ > 110 allow us to assume that the substitution of ligands in iron acetylacetonate of the formed oleate complex leads to the bridging type of coordination with some features of the bidentate type. Using this assumption for the undecylate complex, the difference is ∆ = 1600 − 1436 = 164 cm−1 and

Studies of probe tip materials by atomic force microscopy: a review

• Ke Xu and
• Yuzhe Liu

Beilstein J. Nanotechnol. 2022, 13, 1256–1267, doi:10.3762/bjnano.13.104

• highly fluorescent gold-silver bimetallic nanomaterials with stable fluorescence properties by a simple one-pot method using thiol salts as ligands. TPN-AuAgNCs were synthesised using tiopronin (TPN) as ligand, and the clusters emitted strong red fluorescence with good burst selectivity for Fe3+ after Ag

Role of titanium and organic precursors in molecular layer deposition of “titanicone” hybrid materials

• Arbresha Muriqi and
• Michael Nolan

Beilstein J. Nanotechnol. 2022, 13, 1240–1255, doi:10.3762/bjnano.13.103

• Ti–N bond compared to the Ti–Cl bond and hence a higher reactivity for the Ti(DMA)4 precursor towards the surface and towards the co-reactant is expected. In addition, due to the bulky DMA ligands of Ti(DMA)4, the “reservior” effect, which is very common for small molecules such as TiCl4 [30], DEZ

• AP and the fact that Cl ligands of TiCl4 are small and do not cause steric hindrance. In another study, Ti–organic films were deposited using TiCl4 and the homo/heterobifunctional aromatic molecules hydroquinone (HQ), 4-aminophenol (AP), p-phenylenediamine (PDA) and 4,4′-oxydianiline (ODA). All films

• transfer from the surface OH groups to the Cl ligands of TiCl4 to form HCl as by-product, and the formation of new Ti–O bonds between the TiCl4 molecule and surface oxygen. During the first ligand loss reaction, TiCl4 forms one new Ti–O bond with the surface and one HCl molecule is released. This reaction