Facile chemical routes to mesoporous silver substrates for SERS analysis

• Elina A. Tastekova,
• Alexander Y. Polyakov,
• Anastasia E. Goldt,
• Alexander V. Sidorov,
• Alexandra A. Oshmyanskaya,
• Irina V. Sukhorukova,
• Dmitry V. Shtansky,
• Wolgang Grünert and
• Anastasia V. Grigorieva

Beilstein J. Nanotechnol. 2018, 9, 880–889, doi:10.3762/bjnano.9.82

• (meldonium; enhancement factor of ≈102) that is known for its ability to increase the endurance performance of athletes. Keywords: meldonium; mesoporous silver substrates; silver oxide; surface-enhanced Raman spectroscopy; Introduction Nowadays one of the largest sectors of the global chemical industry is

• fabricate mesoporous silver films from partially oxidized sputtered silver films. Both mesoporous silver cubes and films act as effective SERS mediators as revealed by test experiments employing rhodamine 6G. We also demonstrated the detection of an anti-ischemic mildronate (meldonium) drug, which is widely

• , which is much more appropriate for routine SERS analysis of various water-based compounds. As a key analyte in current manuscript, meldonium (mildronate) was applied to demonstrate SERS activity of the substrates using tintless compounds. Meldonuim is an anti-ischemic drug and a metabolic modulator that