Exploring the potential of polymers: advancements in oral nanocarrier technology

• Rousilândia de Araujo Silva,
• Igor Eduardo Silva Arruda,
• Luise Lopes Chaves,
• Mônica Felts de La Roca Soares and
• Jose Lamartine Soares Sobrinho

Beilstein J. Nanotechnol. 2025, 16, 1751–1793, doi:10.3762/bjnano.16.122

• particles. Materials reduced to this scale exhibit alterations in their physicochemical properties, enhancing their interactions with molecular and cellular processes. Consequently, nanotechnology has diverse pharmaceutical applications, as the nanoencapsulation of drugs improves solubility and

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• overcome these problems [24]. Thus, encapsulation systems create a protective environment for metallodrugs, ensuring that they are delivered to the therapeutic site intact and limiting their interaction with healthy cells. In this way, nanoencapsulation systems drastically improve the efficacy and safety

• control drug release, the nanoencapsulation of clotrimazole silver complex enhances and prolongs the antibacterial activity. Gold complexes Gold compounds have garnered significant attention in recent years for their diverse clinical applications. Widely recognized for their anti-rheumatic and anticancer

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• activated HSCs in liver fibrosis resulted in a loss of the fenestrae, hindering plasma to reach the perisinusoidal space [43]. As the disease progresses, the reduced blood flow and the blockage of portal flow through the liver could diminish the efficiency of drug delivery. Nanoencapsulation as passive

• targeting strategy to the liver To endow passive targeting, specific nanocarriers with extended blood circulation profile are favorable to achieve an improvement in the bioavailability of the active pharmaceutical ingredients (APIs) and an increased accumulation at the target site. Nanoencapsulation of APIs

• limitations, nanoencapsulation of curcumin has been developed, and some of these formulas are undergoing clinical trial evaluation [48][49][50]. By exploiting this technique, the oral bioavailability of encapsulated curcumin could be improved at least ninefold compared to curcumin administered with piperine

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• resistance to severe environments than the antioxidants originating from plants and animals. More interestingly, through nanoencapsulation and nanodelivery, antioxidant nanomaterials improve the pharmacokinetics of natural antioxidants by preventing their degradation under stress conditions [9][10

Sulfur nanocomposites with insecticidal effect for the control of Bactericera cockerelli

• Lany S. Araujo-Yépez,
• Juan O. Tigrero-Salas,
• Vicente A. Delgado-Rodríguez,
• Vladimir A. Aguirre-Yela and
• Josué N. Villota-Méndez

Beilstein J. Nanotechnol. 2023, 14, 1106–1115, doi:10.3762/bjnano.14.91

• used for the encapsulation of nanoinsecticides [16]. The technique used to improve the insecticidal efficacy is called nanoencapsulation [14]. For this purpose, nanometer-sized active ingredients are filled into a thin-walled sac, so that they can be slowly released throughout the whole process. This

• exhibited 100% efficacy. Treatment with thiamethoxam (T7) had a significantly lower insecticidal efficacy than nanocomposite treatments in the evaluated period of time. The control group (T8) showed the lowest values of insecticidal efficacy among all evaluated treatments. Also, nanoencapsulation is known

Nanoarchitectonics to entrap living cells in silica-based systems: encapsulations with yolk–shell and sepiolite nanomaterials

• Celia Martín-Morales,
• Jorge Fernández-Méndez,
• Pilar Aranda and
• Eduardo Ruiz-Hitzky

Beilstein J. Nanotechnol. 2023, 14, 522–534, doi:10.3762/bjnano.14.43

• show promising properties for utilization in photobioreactors and biosensor devices [18][19][20][21]. According to Fakhrullin et al. [22], cellular nanoencapsulation can be nowadays considered as a promising way to develop more complex systems based on nanoshell assemblies using inorganic nanomaterials

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

• Maria Suciu,
• Corina M. Ionescu,
• Alexandra Ciorita,
• Septimiu C. Tripon,
• Dragos Nica,
• Hani Al-Salami and
• Lucian Barbu-Tudoran

Beilstein J. Nanotechnol. 2020, 11, 1092–1109, doi:10.3762/bjnano.11.94

• therapeutic efficacy, and safety studies. Keywords: drug delivery; drug targeting; endocytosis; medical; nanoparticles; superparamagnetic iron oxide nanoparticles (SPIONs); toxicity; Introduction Nanoencapsulation technologies have been researched over the past several decades and have been widely

Association of aescin with β- and γ-cyclodextrins studied by DFT calculations and spectroscopic methods

• Ana I. Ramos,
• Pedro D. Vaz,
• Susana S. Braga and
• Artur M. S. Silva

Beilstein J. Nanotechnol. 2017, 8, 348–357, doi:10.3762/bjnano.8.37

• for Two-dimensional Materials (8–10 September 2015, Chemnitz, Germany) – poster communication “NMR studies on the nanoencapsulation of aescin by the native β- and γ-cyclodextrins” and oral communication “Aescin”.

PLGA nanoparticles as a platform for vitamin D-based cancer therapy

• Maria J. Ramalho,
• Joana A. Loureiro,
• Bárbara Gomes,
• Manuela F. Frasco,
• Manuel A. N. Coelho and
• M. Carmo Pereira

Beilstein J. Nanotechnol. 2015, 6, 1306–1318, doi:10.3762/bjnano.6.135

• conclude that nanoencapsulation in PLGA NPs may offer a new and potentially effective administration strategy of calcitriol that overcomes the actual limitations such as its low bioavailability. Experimental Chemicals PLGA Resomer® RG503H (50:50; Mw 24,000–38,000), ethyl acetate, Pluronic®F127, coumarin-6

Nanoencapsulation of ultra-small superparamagnetic particles of iron oxide into human serum albumin nanoparticles

• Matthias G. Wacker,
• Mahmut Altinok,
• Stephan Urfels and
• Johann Bauer

Beilstein J. Nanotechnol. 2014, 5, 2259–2266, doi:10.3762/bjnano.5.235

• with the surface modification and nanoencapsulation of USPIO into an albumin matrix by using ethanolic desolvation. Particles of narrow size distribution and with a defined particle structure have been achieved. Keywords: diagnostics; HSA; nanoencapsulation; nanoparticles; USPIO; Introduction Over

• for calculation of the USPIO load. Nanoencapsulation of USPIO into human serum albumin USPIO were incorporated into HSA nanoparticles by the well-known desolvation method [15][19]. In principle, an amount of 50 mg of HSA was dissolved in 10 mM sodium chloride solution. The pH was adjusted to between