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Search for "nanomedicine" in Full Text gives 99 result(s) in Beilstein Journal of Nanotechnology.
Framework for automatic information extraction from research papers on nanocrystal devices
Beilstein J. Nanotechnol. 2015, 6, 1872–1882, doi:10.3762/bjnano.6.190
- variety of methods for the extraction of information from research papers [15][16][17]. In the nanoinformatics domain, only a few researchers have attempted to automatically extract information from research papers [18][19][20] and their frameworks are explicitly focused on nanomedicine applications
The Nanomaterial Data Curation Initiative: A collaborative approach to assessing, evaluating, and advancing the state of the field
Beilstein J. Nanotechnol. 2015, 6, 1752–1762, doi:10.3762/bjnano.6.179
- in informatics and computational approaches. This working group includes active membership and input from many communities (e.g., nanoEHS, commercial industry, standards community), but began with a particular emphasis on nanomedicine. From this area of emphasis, the NCIP NanoWG is well-positioned to
Analyzing collaboration networks and developmental patterns of nano-enabled drug delivery (NEDD) for brain cancer
Beilstein J. Nanotechnol. 2015, 6, 1666–1676, doi:10.3762/bjnano.6.169
- (language is English and document type is Article), from 1990 to 2014, from the Science Citation Index Expanded (SCI-Expanded) and the Social Sciences Citation Index (SSCI) of the Web of Science (WoS). Nanomedicine research is a multidisciplinary activity, so exploring the disciplinary distribution is
- , pharmacology & pharmacy, chemistry, neurosciences & neurology, research & experimental medicine and engineering, which indicates that nanomedicine research is a multidisciplinary activity. At the same time, researchers coming from the same institution tend to focus on similar research areas and collaborate on
Experiences in supporting the structured collection of cancer nanotechnology data using caNanoLab
Beilstein J. Nanotechnol. 2015, 6, 1580–1593, doi:10.3762/bjnano.6.161
- ; cancer research; databases; nanomaterials; nanomedicine; Introduction The U.S. annual report to the nation on the state of cancer indicates a steady decline in overall mortality rates, with increases in incidence for many cancers [1]. Internationally, cancer incidence paints a more dramatic picture in
Using natural language processing techniques to inform research on nanotechnology
Beilstein J. Nanotechnol. 2015, 6, 1439–1449, doi:10.3762/bjnano.6.149
- and their associated physico-chemical properties, performance, exposure scenarios, and biological effects. In this paper, we review the different informatics methods that have been applied to patent mining, nanomaterial/device characterization, nanomedicine, and environmental risk assessment. Nine
- , have also been developed [20][21]. In the following section, we describe our method for identifying the nanoinformatics literature discussed in this paper, and then review the different informatics methods that have been applied such as patent mining, nanomaterial/device characterization, nanomedicine
- parameter was examined. Nanomedicine Through targeted and activatible delivery, nanomedicine has the potential to greatly improve drug efficacy while reducing side effects. Improved design can also address emerging challenges to disease treatment such as adaptive resistance. Despite the promise, few
Comparative evaluation of the impact on endothelial cells induced by different nanoparticle structures and functionalization
Beilstein J. Nanotechnol. 2015, 6, 300–312, doi:10.3762/bjnano.6.28
- ; Introduction To advance the field of nanomedicine, innovative nanoparticle formulations with suitable properties for diagnostic imaging, therapy (e.g., magnetic hyperthermia), delivery of drugs and siRNA have been developed. Apart from their feasibility for the respective application many of these
- form double-sided asymmetric shapes right up to nanoflowers offers the possibility for multimodal imaging and multiple drug loading without steric hindrance [28][29][30][31]. These nanoparticles are very new in the field of nanomedicine and poorly investigated despite their interesting features
Oxygen-plasma-modified biomimetic nanofibrous scaffolds for enhanced compatibility of cardiovascular implants
Beilstein J. Nanotechnol. 2015, 6, 254–262, doi:10.3762/bjnano.6.24
- and the O2-plasma-treated nanofibrous scaffolds. Surface atomic composition (atom %) and concentration of the different chemical bonds (%) on the untreated and the O2-plasma-treated nanofibrous scaffolds. Acknowledgements This study was partially supported by the NanoCardio Project “Nanomedicine for
Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes
Beilstein J. Nanotechnol. 2015, 6, 243–253, doi:10.3762/bjnano.6.23
- carbon nanotubes; levodopa; MTT assay; nanomedicine; Parkinson’s disease; PC12 cells; sustained release; Introduction Over the past few years, the revolutionary development of nanomedicine has emerged as one of the most prominent research areas in biomedical science. This interdisciplinary technology is
Mechanical properties of MDCK II cells exposed to gold nanorods
Beilstein J. Nanotechnol. 2015, 6, 223–231, doi:10.3762/bjnano.6.21
- of nanomedicine results from both their therapeutic and diagnostic potential based on their tuneable size in the range of 1–100 nm [1][2][3][4][5]. Being in the size-regime of cellular components such as DNA and proteins, nanoparticles are capable to overcome native dielectric barriers like the cell
Caveolin-1 and CDC42 mediated endocytosis of silica-coated iron oxide nanoparticles in HeLa cells
Beilstein J. Nanotechnol. 2015, 6, 167–176, doi:10.3762/bjnano.6.16
- Nils Bohmer Andreas Jordan Project Biomedical Nanotechnologies, Charité University Medicine, 13353 Berlin, Germany MagForce Nanotechnologies AG, 12489 Berlin, Germany 10.3762/bjnano.6.16 Abstract Nanomedicine is a rapidly growing field in nanotechnology, which has great potential in the
- technique for the treatment of various diseases in the 21st century. Today nanomedicine has spread in many different subareas, which are working highly interdisciplinary on the development of new therapy concepts [1]. One of the most important fields is the early detection and treatment of cancer. Therefore
- commercial use of iron oxide nanoparticles and their diversified development for future applications in nanomedicine, little is known about the way they are internalized by tumor cells or cells of other origins. By the use of microscopic techniques previous studies showed, that iron oxide nanoparticles often
The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice
Beilstein J. Nanotechnol. 2015, 6, 111–123, doi:10.3762/bjnano.6.11
- makes them a highly promising tool for various applications in nanobioscience and nanomedicine [1][2][3][4][5][6]. Since many Qdots contain cadmium or other toxic elements, the release of potential toxic metals is a major concern with respect to biosafety. Many studies have demonstrated the toxicity of
Synthesis of boron nitride nanotubes and their applications
Beilstein J. Nanotechnol. 2015, 6, 84–102, doi:10.3762/bjnano.6.9
- of nanomedicine. The covalent grafting of BNNTs with human transferrin, linked through a carbamide bond, was reported [67]. The transferrin–BNNTs were tested on primary human umbilical vein endothelial cells (HUVECs) to investigate their cellular uptake. It was concluded that the functionalization of
- the BNNTs via a targeting protein could generate smart and selective nanocarriers to be used in nanomedicine [67]. Physical modifications For these types of modifications, weak interactions such as π–π, hydrophobic, and van der Waals forces are utilized to coat the BNNTs with mostly a polymeric
The fate of a designed protein corona on nanoparticles in vitro and in vivo
Beilstein J. Nanotechnol. 2015, 6, 36–46, doi:10.3762/bjnano.6.5
- vivo for the respective nanoparticle uptake. Keywords: albumin; 59Fe; 125I; organ uptake; protein corona; SPIOs; transferrin; Introduction Nanoparticles (NPs) have unique capabilities to interact with cells and organs which mark them as attractive working material in nanobioscience and nanomedicine
Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles – a fluorescence correlation spectroscopy study
Beilstein J. Nanotechnol. 2014, 5, 2036–2047, doi:10.3762/bjnano.5.212
- attention. Considering the wide variety of existing NPs and the complexity of biological fluids, substantial variations in their mutual interactions can be expected. Knowledge of these interactions is, however, indispensible for safe applications of NPs in the field of nanomedicine, for example, as highly
Carbon nano-onions (multi-layer fullerenes): chemistry and applications
Beilstein J. Nanotechnol. 2014, 5, 1980–1998, doi:10.3762/bjnano.5.207
- , could be modified with flavonoid compounds, for the example quercitin, a compound known for its anti-inflammatory potential [49], giving rise to future applications in nanomedicine. Some additional metal oxide-containing composite materials were studied for applications as electrode materials in
Biocompatibility of cerium dioxide and silicon dioxide nanoparticles with endothelial cells
Beilstein J. Nanotechnol. 2014, 5, 1795–1807, doi:10.3762/bjnano.5.190
- ]. SiO2 nanoparticles are employed in the fabrication of electric and thermal insulators [6], as drug-delivery systems in nanomedicine [7][8], as anticaking and thickener agents in food production [9][10], as well as in cosmetics, drugs and printer toners [11]. Human exposure to these nanoparticles arises
The surface properties of nanoparticles determine the agglomeration state and the size of the particles under physiological conditions
Beilstein J. Nanotechnol. 2014, 5, 1774–1786, doi:10.3762/bjnano.5.188
- cosmetics, and even in food [51]. Furthermore, both silica and siloxane particles are promising candidates for applications in the field of nanomedicine. In particular, the poly(organosiloxane) particles offer high versatility and flexibility with regard to architecture, composition and functionalization
Precise quantification of silica and ceria nanoparticle uptake revealed by 3D fluorescence microscopy
Beilstein J. Nanotechnol. 2014, 5, 1616–1624, doi:10.3762/bjnano.5.173
- properties have been described as beneficial applications in nanomedicine [17][18][19]. On the other hand, oxidative stress and impaired cell viability were shown to be a function of the particle dose and the exposure time [1][20]. However, most of the studies concerning the interaction of silica and ceria
The protein corona protects against size- and dose-dependent toxicity of amorphous silica nanoparticles
Beilstein J. Nanotechnol. 2014, 5, 1380–1392, doi:10.3762/bjnano.5.151
- interface in general. Keywords: biobarrier; gastrointestinal tract; high-throughput profiling; nanomedicine; nanotoxicity; Introduction Besides the wide use of nanomaterials in industrial products, biomedical applications of nanoparticles (NP) are steadily increasing [1][2][3][4][5]. However, despite
Nanodiamond-DGEA peptide conjugates for enhanced delivery of doxorubicin to prostate cancer
Beilstein J. Nanotechnol. 2014, 5, 937–945, doi:10.3762/bjnano.5.107
- Birmingham (UAB), 1530 3rd Avenue South, Birmingham, AL 35294, USA Department of Materials Science and Engineering, Tuskegee University (TU), 1200 W Montgomery Rd, Tuskegee, AL 36088, USA 10.3762/bjnano.5.107 Abstract The field of nanomedicine has emerged as an approach to enhance the specificity and
- toxicity by incorporating mechanisms for targeted delivery of chemotherapeutics. Nanomedicine has become a viable solution for the specificity and toxicity problems with current chemotherapy treatment regimens [6][7][8][9]. Nanoparticles have facilitated tumor targeting and drug delivery in a variety of
Morphological characterization of fullerene–androsterone conjugates
Beilstein J. Nanotechnol. 2014, 5, 374–379, doi:10.3762/bjnano.5.43
- Madrid, Spain Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain Centre on Bioengineering, Biomaterials and Nanomedicine, PCB, 08028-Barcelona, Spain Department of Organic Chemistry, University of Barcelona, 08028-Barcelona, Spain School of Chemistry
Functionalization of vertically aligned carbon nanotubes
Beilstein J. Nanotechnol. 2013, 4, 129–152, doi:10.3762/bjnano.4.14
- tensile strength [9] and elastic modulus [10], CNTs form the strongest and stiffest material that humans have created. These properties offer a wide range of potential applications [11][12], for electronic devices, energy storage and transport, nanocomposite materials, and nanomedicine. The as-synthesized
Dynamics of capillary infiltration of liquids into a highly aligned multi-walled carbon nanotube film
Beilstein J. Nanotechnol. 2011, 2, 311–317, doi:10.3762/bjnano.2.36
- for non-polar liquids [5]. One of the cutting edge areas of research exploiting CNTs is nanomedicine where the interface of CNTs with a liquid environment is essential, e.g., subcutaneous glucose sensors [6], microcatheters [7] or tissue engineering materials [8]. Until now, physical compatibility of
Magnetic coupling mechanisms in particle/thin film composite systems
Beilstein J. Nanotechnol. 2010, 1, 101–107, doi:10.3762/bjnano.1.12
- nanoparticles (NPs) represent at least one of the constituent materials [3] have generated much attention. A large number of investigations can be found that address potential technological applications, preparation methods and fundamental properties of magnetic NPs, such as in photonics [6][7], nanomedicine [8
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