Search results
Search for "silica" in Full Text gives 366 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.
Classification and application of metal-based nanoantioxidants in medicine and healthcare
Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36
- , Kharlamov et al. investigated 180 patients diagnosed with coronary artery disease (CAD). Their findings unveiled a notable regression of coronary atherosclerosis associated with plasmonic photothermal therapy using silica–gold NPs (SiO2-AuNPs) [177]. Metal-based NPs exhibit the ability to scavenge free
Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study
Beilstein J. Nanotechnol. 2024, 15, 256–269, doi:10.3762/bjnano.15.24
- , as they increase permeability and retention effect in solid tumors, enabling precise application to the targeted cells. Various structures such as silica-based conjugates, inorganic polymers, ceramic nanomaterials, gold, iron oxide, and noble metal nanoparticles have been utilized [9][10]. Among the
Graphene removal by water-assisted focused electron-beam-induced etching – unveiling the dose and dwell time impact on the etch profile and topographical changes in SiO2 substrates
Beilstein J. Nanotechnol. 2024, 15, 190–198, doi:10.3762/bjnano.15.18
- using electron beams and gas precursors was not widely recognized at the time when earlier studies regarding morphological changes in silica upon the electron irradiation were performed [24]. Therefore, neither of the electron-beam-induced changes into the SiO2 surface during the water purification of
- FEBID materials were taken into account. The topographical changes in silica can be a consequence of removing Si and O atoms by OH− groups, which are the product of adsorbed water molecules upon electron beam exposure. The related process of silica removal by hot water molecules at a high pressure has
- dissociation products of water molecules and thus could be actively involved in the SiO2 removal process. Our results, showing topographical changes in SiO2 are partially consistent with former studies reported by Steven Kalceff et al. [24] of either swelling or deswelling of a silica substrate upon electron
Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics
Beilstein J. Nanotechnol. 2024, 15, 180–189, doi:10.3762/bjnano.15.17
- were performed in both 0.1× PBS (13.7 mM of NaCl, 0.27 mM of KCl, 1 mM of Na2HPO4, and 0.18 mM of KH2PO4, pH 7.4) and animal cell culture media containing DMEM and 10% FBS. Scanning electron microscopy For scanning electron microscopy (SEM) experiments, 10 μL of F127-folate@NP was loaded on the silica
Modification of graphene oxide and its effect on properties of natural rubber/graphene oxide nanocomposites
Beilstein J. Nanotechnol. 2024, 15, 168–179, doi:10.3762/bjnano.15.16
- characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy, contact angle, thermal gravimetric analysis, and scanning electron microscopy. The XRD results showed the appearance of an amorphous region of silica particles at a diffraction angle of 22°. The formation of silica was
- investigated by 29Si NMR, and it was found that the hydrolysis and condensation of VTES proceed more completely in basic conditions than in acidic conditions. The silica content of GO-VTES(b) was 43%, which is higher than that of GO-VTES(a) (8%). Morphology of silica was observed by SEM. The DPNR/GO-VTES
- , GO has quite poor compatibility with NR. It is necessary to modify GO to have a better interaction with the NR matrix. Various researchers have attempted to functionalize GO with silane coupling agents to prepare hybrid GO/silica fillers [25][26]. The concept is based on the hydrolysis and
Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency
Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7
- , iron oxide, and mesoporous silica nanoparticles) [4]. Additionally, nanocarrier-free systems, such as drug nanocrystals, are also used to improve the delivery of poorly soluble drugs [5][6]. In our previous study, the saturation concentration of BBR in water was 2.0 mg/mL, while BBR nanoparticles
Nanotechnological approaches in the treatment of schistosomiasis: an overview
Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2
- ) are derived from metals or silica [25]. The most common metal used in the production of IN found in this work was gold, even though it was also possible to observe a great amount of works using silver and zinc (Figure 5). While silica-derived nanoparticles are used in the treatment against
Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems
Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95
- biological applications Mechanical properties of particles have a significant impact on the cell–particle interaction; most particles are reported to be taken up faster when they are more rigid [36]. Some materials such as phospholipids and organic silica NPs with a hyaluronic acid coating show superior
- variable elasticity were prepared by immersing mesoporous silica nanoparticles in carboxybetaine methacrylate (CBMA) and crosslinking those with different amounts of carboxybetaine dimethacrylate (CBMAX). Particles with Young’s moduli between 4.5 and 162 MPa (measured in air) were obtained. By measuring
- convinced that elasticity as a formulation parameter can help to promote more nanoparticulate drug delivery systems to be translated to the clinics. (A) Height image of gelatin nanoparticles on a silica surface imaged in Milli-Q® water at 37 °C in the quantitative imaging mode. (B) A force–distance curve
A multi-resistance wide-range calibration sample for conductive probe atomic force microscopy measurements
Beilstein J. Nanotechnol. 2023, 14, 1141–1148, doi:10.3762/bjnano.14.94
- -AFM imaging and I–V curves measurement to define the conditions for calibrated measurements. Calibration sample design and fabrication The sample developed in this work consisted of a square fused silica substrate (11 mm wide, 2 mm thick), on which gold connection lines and pads were fabricated by
- droplets (F42240, lead-free solder paste – class 5, CIF, France). The fused silica substrate was placed on a heating plate set to 270 °C, which required around 3 min to reach the melting temperature of the solder droplets (217 °C), as observed under an optical microscope. Upon cooling, 16 SMD resistors
Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays
Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82
- by changing the composition of core–shell nanoparticles of silica and gold. A Au–Ag nanocomposite material developed by Lin et al. underwent structural changes, resulting in reduced photothermal conversion in the presence of H2S [78]. A multifunctional nanocomposite based on Au–Pt was developed by Li
Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics
Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75
- copper-free click reaction to decorate fluorescent silica NPs with bicyclononyne. They exposed the NPs to media that mimicked in vitro culture conditions (10% serum) and biological fluids present in vivo (100% serum). They observed an increase in size and a slight decrease in negative charge in serum
- -containing media, which confirmed protein corona formation. The protein corona establishes a barrier between the ligand and the target, significantly reducing the NP targeting efficiency as compared to bare NPs [79]. Salvati et al. developed transferrin (Tf)-modified fluorescent silica NPs to evaluate the
- increased the binding affinity of the NPs to bind to the Zika virus NS1 [84]. In contrast, Dai et al. examined the effect of protein corona formation on the targeting ability of silica-poly(methacrylic acid)-PEG-AntiHER2 NPs. They demonstrated that a protein corona from human serum affects the NPs surface
A wearable nanoscale heart sound sensor based on P(VDF-TrFE)/ZnO/GR and its application in cardiac disease detection
Beilstein J. Nanotechnol. 2023, 14, 819–833, doi:10.3762/bjnano.14.67
- are welded onto the edges of the copper foil. In the mold shown in Figure 2, a thin layer of silica gel is injected and left to stand until it is dry. The nanofilm attached to the electrode is then placed in the mold, and an appropriate amount of silica gel is slowly injected until the film is
- sensor after bending. It was observed that the sensor encapsulated by silica gel was highly flexible and could fit snugly onto the skin. Additionally, the food-grade silica gel used in the outermost layer is ecologically friendly, harmless to human health, and makes for a great wearable, flexible
- piezoelectric nanoscale heart sensor, and the outermost layer of silica gel effectively protected the flexible nanofilm and adhered to the skin. In this paper, the acoustic-electric conversion performance of P(VDF-TrFE)/ZnO/GR piezoelectric composite films was evaluated using a self-built acoustic-electric
Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments
Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63
- resulted in loss or overcoating of the surface citrate, and, in some cases, agglomeration [10]. Exposure to vitamin C and glutathione led to dissolution-accompanied aggregation of mesoporous silica CeO2 nanoparticles [35]. The shortening of ceria nanorods from 25 to 8 nm after 14 days at 200 °C was
Nanoarchitectonics to entrap living cells in silica-based systems: encapsulations with yolk–shell and sepiolite nanomaterials
Beilstein J. Nanotechnol. 2023, 14, 522–534, doi:10.3762/bjnano.14.43
- microorganisms, that is, cyanobacteria and yeast cells, have been immobilized in silica and silicate-based substrates organized as nanostructured materials. In a first attempt, matrices based on bionanocomposites of chitosan and alginate incorporating sepiolite clay mineral and shaped as films, beads, or foams
- have been explored for the immobilization of cyanobacteria. It has been observed that this type of biohybrid substrates leads to serious problems regarding the long-time survival of the encapsulated microorganisms. Alternative procedures using silica-based matrices with low sodium content, generated by
- sol–gel methods, as well as pre-synthesised yolk–shell bionanohybrids have been studied subsequently. Optical microscopy and SEM confirm that the silica shell microstructures provide a reduced contact between cells. The inorganic matrix increases the survival of the cells and maintains their
Plasmonic nanotechnology for photothermal applications – an evaluation
Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33
Quasi-guided modes resulting from the band folding effect in a photonic crystal slab for enhanced interactions of matters with free-space radiations
Beilstein J. Nanotechnol. 2023, 14, 322–328, doi:10.3762/bjnano.14.27
- larger than that of most plasmonic nanoantennas, suggesting the great potential of these QGMs for enhanced light–matter interactions. We use GMs supported by a regular PCS structure composed of a square lattice of air holes perforating a thin silicon (refractive index: 3.45) film on a silica (refractive
Biocatalytic synthesis and ordered self-assembly of silica nanoparticles via a silica-binding peptide
Beilstein J. Nanotechnol. 2023, 14, 280–290, doi:10.3762/bjnano.14.25
- and proteins, have been demonstrated to be useful in the synthesis and self-assembly of inorganic nanostructures. Herein, we describe a simple Stöber-based method wherein both the synthesis and the self-assembly of SiO2 nanoparticles can be facilitated by a silica-binding peptide (SiBP). We
- . The results presented here provide a biomimetic route to the single-step synthesis and assembly of SiO2 nanoparticles into colloidal gels or opal-like structures. Keywords: biocatalysis; biomimetics; nanoparticle; peptide; self-assembly; silica; Introduction Ordered structures of nanoparticles have
- utility of a silica-binding peptide (SiBP) in the single-step synthesis and self-assembly of SiO2 nanoparticles into ordered 3D structures. The SiBP is a member of the “solid-binding peptides” family. Solid-binding peptides are designed to have strong and often specific binding affinity to solid surfaces
Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer
Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23
- barriers by the use of different groups of particles carrying various functional modalities. Tasciotti et al. proposed a multistage delivery system composed of stage-1 mesoporous silica particles with improved deposition in the vascular endothelium, optimized for crossing the endothelial barrier through
- surface, triggered by protease degradation after tumor homing by the EPR effect [112]. Mesoporous silica vesicles (MSVs; dav = 3 μm) with high affinity to tumor vasculature were also described by Blanco et al. as a platform for the triggered release of various therapeutic nanoscale vectors (liposomes
- )-functionalized nanoporous silica particles loaded with a poly(ʟ-glutamic acid) pH-cleavable linker–doxorubicin conjugate, which self-assembles into NPs after its release from the iNPG [114]. Li et al. designed a multistage nanocarrier for NSCLC targeting, composed of icotinib-loaded amphiphilic chitosan micelles
Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems
Beilstein J. Nanotechnol. 2023, 14, 218–232, doi:10.3762/bjnano.14.21
- are disassembled to release the encapsulated drugs. β-CyD units have been connected to mesoporous silica nanoparticles via a disulfide linkage, and azobenzene molecules have been bound to a galactose-grafted polymer [49]. Prior to photoirradiation, the trans isomer of azobenzene forms an inclusion
- complex with β-CyD bound to the silica nanoparticles and seals the pores of nanoparticles in which drugs are encapsulated. Under these conditions, the composite is stable, because azobenzene is accommodated in the cavity of β-CyD, and sterically protects the disulfide linkage from reductive cleavage by
- , only the trans isomer of mAzo efficiently forms inclusion complexes with β-CyD (Figure 2). The surface of mesoporous silica nanoparticles was modified with β-CyD and covered with a polymer bearing mAzo units [51]. Drugs were loaded in the pores of the silica nanoparticles. Prior to photoirradiation
Characterisation of a micrometer-scale active plasmonic element by means of complementary computational and experimental methods
Beilstein J. Nanotechnol. 2023, 14, 110–122, doi:10.3762/bjnano.14.12
- configuration was placed horizontally at the centre of the stage rotating at θ. This configuration consists of a fused silica prism with a sapphire slide optically coupled using refractive index matching oil (n = 1.516). This configuration was also used in the simulations. A sapphire slide was used as the
Solvent-induced assembly of mono- and divalent silica nanoparticles
Beilstein J. Nanotechnol. 2023, 14, 52–60, doi:10.3762/bjnano.14.6
- Particles with attractive patches are appealing candidates to be used as building units to fabricate novel colloidal architectures by self-assembly. Here, we report the synthesis of one-patch silica nanoparticles, which consist of silica half-spheres whose concave face carries in its center a polymeric
- assembly of silica/polystyrene (PS) dumbbells [28] and silica nanoparticles with two PS patches (2-PSN) [29][30][31] into multipod-like clusters and colloidal chains, respectively. We have recently reported that the same strategy can be used to assemble one-patch silica nanoparticles (1-PSN) with a well
- ., salty water). We show that only dimers or trimers can be obtained due to steric hindrance induced by the large silica cap of the patchy nanoparticles. The present study also extends the insights we recently gained about the capability of using 1-PSN with a PPSR of 0.60 as chain stoppers [31]. We show
Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy
Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118
- over anhydrous Na2SO4, filtered, and concentrated under reduced pressure to afford the crude product. The crude product was purified via silica gel column chromatography using DCM/PE = 1:1 as eluent to obtain a green solid. 1H NMR (500 MHz, CDCl3) δ 8.06 (d, J = 16.5 Hz, 2H), 7.54 (d, J = 8.7 Hz, 4H
Studies of probe tip materials by atomic force microscopy: a review
Beilstein J. Nanotechnol. 2022, 13, 1256–1267, doi:10.3762/bjnano.13.104
- bias-assisted electroreduced gold ions in mesoporous silica films on a conductive substrate. It works in the air with high relative humidity (RH) at room temperature and leads to the growth of fine wires attached to the tip with tens to hundreds of nanometers. Under room temperature conditions with
- high RH, the gold ions loaded in the specific substrate of the mesoporous silica layer are biased, and the gold ions therein migrate upward and accumulate at the tip site of the probe, forming gold nanowires. The length of the gold nanowires can be effectively tuned in the range of 10–100 nm with a
- criteria required for a high-quality AFM conductive probe. Colloidal probe Colloidal probes (CPs) [47] can simulate the determination of forces between many types of colloidal particles, such as silica-alumina cellulose, and have several advantages for accurate force measurements: tunable and well
Roll-to-roll fabrication of superhydrophobic pads covered with nanofur for the efficient clean-up of oil spills
Beilstein J. Nanotechnol. 2022, 13, 1228–1239, doi:10.3762/bjnano.13.102
- , widely used method for obtaining superhydrophobic surfaces is the use of silica-based films, which can be applied by dipping the object in gel or via aerosol spray [15]. While providing excellent superhyrophobicity and an easy application even on very large surfaces, these films are not particularly
A super-oscillatory step-zoom metalens for visible light
Beilstein J. Nanotechnol. 2022, 13, 1220–1227, doi:10.3762/bjnano.13.101
- ) that enables super-resolution focusing with two working modes corresponding to different focal lengths. The designed SSL is composed of a fused silica substrate sandwiched by two metasurfaces based on the geometric phase principle. The optical powers with opposite sign of the front and back
- unchanged. With the geometric optics theory [27], one can get where and are the focal lengths of front and rear metasurfaces, d and n are the thickness and refractive index of the glass substrate, and M is the zoom ratio. Here, we choose fused silica glass (the refractive index is about 1.457 at a
- optimization efficiency referring to the previous work. Second, the two designed metasurfaces are cemented with the fused silica substrate. In turn, the back focal length, phase coefficients, and substrate thickness were added as optimization variables in order to minimize the RMS focal spot size for different
Other Beilstein-Institut Open Science Activities
