Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics

• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan-Thang Cao,
• Vy Tran-Anh and
• Hieu Vu Quang

Beilstein J. Nanotechnol. 2024, 15, 180–189, doi:10.3762/bjnano.15.17

• of Applied Technology and Sustainable Development, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam Department of Biotechnology, NTT Hi-tech institute, Nguyen Tat Thanh University, Ho Chi Minh City, 700000, Vietnam 10.3762/bjnano.15.17 Abstract Theragnostics has become a popular term

• nanocarrier that can be loaded with the chemotherapeutic medication chlorambucil and magnetic resonance imaging agents (e.g., iron oxide nanoparticles and near-infrared fluorophore IR780) for theragnostics. Poly(lactic-co-glycolic acid) was combined with the aforementioned ingredients to generate poly(vinyl

• of these systems to serve as medication and imaging agent carriers for cancer treatment and diagnostics, respectively. Keywords: cancer; chlorambucil; F127-folate; IR780; iron oxide nanoparticles; PLGA; theragnostics; Introduction Theragnostic nanoparticles (NPs) are a diagnostic and therapeutic

Electrokinetic characterization of synthetic protein nanoparticles

• Daniel F. Quevedo,
• Cody J. Lentz,
• Adriana Coll de Peña,
• Yazmin Hernandez,
• Nahal Habibi,
• Rikako Miki,
• Joerg Lahann and
• Blanca H. Lapizco-Encinas

Beilstein J. Nanotechnol. 2020, 11, 1556–1567, doi:10.3762/bjnano.11.138

• for producing subcompartments within particles. By localizing proteins at the nanoscale, PNPs could be used to control the release and delivery of therapeutics, theragnostics, and enzymatic cascades [10]. Although previously developed methods to produce PNPs, such as coacervation, self-assembly, and

• ). Effect of small size differences and fluorescent dyes For potential applications in theragnostics, in which fluorescently labeled particles could be needed, we were first interested in investigating whether the incorporation of different fluorescent dyes in our particles could affect the particle

Surface coating affects behavior of metallic nanoparticles in a biological environment

• Darija Domazet Jurašin,
• Marija Ćurlin,
• Ivona Capjak,
• Tea Crnković,
• Marija Lovrić,
• Michal Babič,
• Daniel Horák,
• Ivana Vinković Vrček and
• Srećko Gajović

Beilstein J. Nanotechnol. 2016, 7, 246–262, doi:10.3762/bjnano.7.23

• development of nanomaterials for theragnostics is an ambitious goal with many parameters to assess. Conclusion The lack of fundamental knowledge about the biocompatibility of metal-based nanomaterials and their effect and behavior in biological systems may restrict the capability to establish principles used