Synthesis and characterization of a hyper-branched water-soluble β-cyclodextrin polymer

Scholarly Works

• Matencio, A.; Monfared, Y. K.; Caldera, F.; Mahmoodian, M.; López-Nicolás, J. M.; Zakeri-Milani, P.; Cavalli, R.; Trotta, F. Commercial and non-commercial cyclodextrin derivatives as a novel therapy to improve gout's disease and hyperuricemia. International journal of pharmaceutics 2025, 684, 126148. doi:10.1016/j.ijpharm.2025.126148
• Hoti, G.; Bajwa, N.; Caldera, F.; Singh, P. A.; Hussein, I.; Cecone, C.; Matencio, A.; Spagnolo, R.; Argenziano, M.; Cavalli, R.; Madan, J.; Trotta, F. Cyclodextrin-based therapeutics delivery systems: A review of current clinical trials. Current research in pharmacology and drug discovery 2025, 9, 100232. doi:10.1016/j.crphar.2025.100232
• Bahmei, F.; Hemmati, A.; Ghaemi, A.; Bahreini, M. Improving hypercrosslinked polymer CO2/N2 selective separation through tuning polymer's porous properties: Optimization using RSM-BBD. Journal of CO2 Utilization 2024, 88, 102926. doi:10.1016/j.jcou.2024.102926
• Agnes, M.; Mazza, A.; Malanga, M.; Manet, I. Sculpturing the future of water-soluble cyclodextrin branched polymers in pharmaceutical applications. Journal of materials chemistry. B 2024, 12, 7969–7976. doi:10.1039/d4tb01165a
• Kashani, E.; Maghsoudi, S.; Rezania, H.; Yarazavi, M.; Hajiabbas, M.; Benkovics, G.; Bilensoy, E.; Lacík, I.; Heydari, A. Cyclodextrin polymers containing ionizable and ionic groups: A comprehensive review from classifications and synthesis methods to applications. Materials Today Chemistry 2024, 39, 102186. doi:10.1016/j.mtchem.2024.102186
• Chen, G.; Yu, J.; Wu, L.; Ji, X.; Xu, J.; Wang, C.; Ma, S.; Miao, Q.; Wang, L.; Wang, C.; Lewis, S. E.; Yue, Y.; Sun, Z.; Liu, Y.; Tang, B.; James, T. D. Fluorescent small molecule donors. Chemical Society reviews 2024, 53, 6345–6398. doi:10.1039/d3cs00124e
• Salgın, S.; Çetintaş, H. İ.; Salgın, U. Synthesis and characterization of β-cyclodextrin polymers and its performance as a drug carrier. Inorganic and Nano-Metal Chemistry 2024, 55, 934–945. doi:10.1080/24701556.2024.2355514
• Pyrak, B.; Rogacka-Pyrak, K.; Gubica, T.; Szeleszczuk, Ł. Exploring Cyclodextrin-Based Nanosponges as Drug Delivery Systems: Understanding the Physicochemical Factors Influencing Drug Loading and Release Kinetics. International journal of molecular sciences 2024, 25, 3527. doi:10.3390/ijms25063527
• Laneri, F.; Licciardello, N.; Suzuki, Y.; Graziano, A. C. E.; Sodano, F.; Fraix, A.; Sortino, S. A Supramolecular Nanoassembly of Lenvatinib and a Green Light-Activatable NO Releaser for Combined Chemo-Phototherapy. Pharmaceutics 2022, 15, 96. doi:10.3390/pharmaceutics15010096
• Monfared, Y. K.; Mahmoudian, M.; Hoti, G.; Bisericaru, D. M.; Caldera, F.; Cavalli, R.; Zakeri-Milani, P.; Matencio, A.; Trotta, F. Hyper-Branched Cyclodextrin-Based Polymers as Anticoagulant Agents: In Vitro and In Vivo Studies. Bioengineering (Basel, Switzerland) 2022, 9, 765. doi:10.3390/bioengineering9120765
• Monfared, Y. K.; Mahmoudian, M.; Cecone, C.; Caldera, F.; Haiaty, S.; Heidari, H. R.; Rahbarghazi, R.; Matencio, A.; Zakeri-Milani, P.; Trotta, F. Hyper-Branched Cationic Cyclodextrin Polymers for Improving Plasmid Transfection in 2D and 3D Spheroid Cells. Pharmaceutics 2022, 14, 2690. doi:10.3390/pharmaceutics14122690
• Francese, R.; Cecone, C.; Costantino, M.; Hoti, G.; Bracco, P.; Lembo, D.; Trotta, F. Identification of a βCD-Based Hyper-Branched Negatively Charged Polymer as HSV-2 and RSV Inhibitor. International journal of molecular sciences 2022, 23, 8701. doi:10.3390/ijms23158701
• Hoti, G.; Appleton, S. L.; Pedrazzo, A. R.; Cecone, C.; Matencio, A.; Trotta, F.; Caldera, F. Strategies to Develop Cyclodextrin-Based Nanosponges for Smart Drug Delivery. Smart Drug Delivery; IntechOpen, 2022. doi:10.5772/intechopen.100182
• Agnes, M.; Pancani, E.; Malanga, M.; Fenyvesi, E.; Manet, I. Implementation of Water-Soluble Cyclodextrin-Based Polymers in Biomedical Applications: How Far Are We?. Macromolecular bioscience 2022, 22, e2200090. doi:10.1002/mabi.202200090
• Matencio, A.; Rubin Pedrazzo, A.; Difalco, A.; Navarro-Orcajada, S.; Khazeai Monfared, Y.; Conesa, I.; Rezayat, A.; López-Nicolás, J. M.; Trotta, F. Advances and Classification of Cyclodextrin-Based Polymers for Food-Related Issues. Polymers 2021, 13, 4226. doi:10.3390/polym13234226
• Caldera, F.; Moramarco, A.; Cesano, F.; Anceschi, A.; Damin, A.; Zanetti, M. Preparation and Carbonization of Glucose and Pyromellitic Dianhydride Crosslinked Polymers. 2021, 7, 56. doi:10.3390/c7030056
• Köse, K.; Tüysüz, M.; Aksüt, D.; Uzun, L. Modification of cyclodextrin and use in environmental applications. Environmental science and pollution research international 2021, 29, 1–28. doi:10.1007/s11356-021-15005-y
• Rizzi, V.; Gubitosa, J.; Signorile, R.; Fini, P.; Cecone, C.; Matencio, A.; Trotta, F.; Cosma, P. Cyclodextrin nanosponges as adsorbent material to remove hazardous pollutants from water: The case of ciprofloxacin. Chemical Engineering Journal 2021, 411, 128514. doi:10.1016/j.cej.2021.128514
• Girek, T.; Koziel, K.; Girek, B.; Ciesielski, W. CD Oxyanions as a Tool for Synthesis of Highly Anionic Cyclodextrin Polymers. Polymers 2020, 12, 2845. doi:10.3390/polym12122845
• Tannous, M.; Caldera, F.; Hoti, G.; Dianzani, U.; Cavalli, R.; Trotta, F. Drug-Encapsulated Cyclodextrin Nanosponges. Methods in molecular biology (Clifton, N.J.) 2020, 2207, 247–283. doi:10.1007/978-1-0716-0920-0_19

Explore citations to this article at