Anomalous diffusion of Ibuprofen in cyclodextrin nanosponge hydrogels: an HRMAS NMR study

Monica Ferro, Franca Castiglione, Carlo Punta, Lucio Melone, Walter Panzeri, Barbara Rossi, Francesco Trotta and Andrea Mele
Beilstein J. Org. Chem. 2014, 10, 2715–2723.

Cite the Following Article

Anomalous diffusion of Ibuprofen in cyclodextrin nanosponge hydrogels: an HRMAS NMR study
Monica Ferro, Franca Castiglione, Carlo Punta, Lucio Melone, Walter Panzeri, Barbara Rossi, Francesco Trotta and Andrea Mele
Beilstein J. Org. Chem. 2014, 10, 2715–2723.

How to Cite

Ferro, M.; Castiglione, F.; Punta, C.; Melone, L.; Panzeri, W.; Rossi, B.; Trotta, F.; Mele, A. Beilstein J. Org. Chem. 2014, 10, 2715–2723. doi:10.3762/bjoc.10.286

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Vanoli, V.; Pietrowska, J.; de Araujo Lima e Souza, G.; Di Pietro, M. E.; Briatico Vangosa, F.; Mele, A.; Castiglione, F. Supramolecular Hydrophobic Eutectogels Based on Menthol-Thymol as Thermo- and pH-Responsive Drug Delivery Systems. ACS Applied Engineering Materials 2024, 2, 388–396. doi:10.1021/acsaenm.3c00697
  • Kumar, S.; Malviya, R. Dietary fibers and their derivatives for drug delivery applications: Advances and prospective. Journal of Drug Delivery Science and Technology 2023, 89, 105084. doi:10.1016/j.jddst.2023.105084
  • Utzeri, G.; Murtinho, D.; Valente, A. J. M. Introduction to Cyclodextrin-Based Nanosponges. Nanosponges for Environmental Remediation; Springer Nature Switzerland, 2023; pp 87–115. doi:10.1007/978-3-031-41077-2_5
  • Molinar, C.; Navarro-Orcajada, S.; Ansari, I. A.; Conesa, I.; Hoti, G.; Monfared, Y. K.; Matencio, A.; Scomparin, A.; López-Nicolás, J. M.; Cavalli, R.; Trotta, F. Cyclodextrins and Cyclodextrin-Based Nanosponges for Anti-Cancer Drug and Nutraceutical Delivery. Targeted Cancer Therapy in Biomedical Engineering; Springer Nature Singapore, 2023; pp 597–629. doi:10.1007/978-981-19-9786-0_17
  • Vanoli, V.; Massobrio, G.; Pizzetti, F.; Mele, A.; Rossi, F.; Castiglione, F. Bijels as a Fluid Labyrinth for Drugs: The Effect of Nanoparticles on the Release Kinetics of Ethosuximide and Dimethyl Fumarate. ACS omega 2022, 7, 42845–42853. doi:10.1021/acsomega.2c04834
  • Vanoli, V.; Delleani, S.; Casalegno, M.; Pizzetti, F.; Makvandi, P.; Haugen, H.; Mele, A.; Rossi, F.; Castiglione, F. Hyaluronic acid-based hydrogels: Drug diffusion investigated by HR-MAS NMR and release kinetics. Carbohydrate polymers 2022, 301, 120309. doi:10.1016/j.carbpol.2022.120309
  • Skwierawska, A. M.; Bliźniewska, M.; Muza, K.; Nowak, A.; Nowacka, D.; Zehra Syeda, S. E.; Khan, M. S.; Łęska, B. Cellulose and its derivatives, coffee grounds, and cross-linked, β-cyclodextrin in the race for the highest sorption capacity of cationic dyes in accordance with the principles of sustainable development. Journal of hazardous materials 2022, 439, 129588. doi:10.1016/j.jhazmat.2022.129588
  • Hoti, G.; Appleton, S. L.; Pedrazzo, A. R.; Cecone, C.; Matencio, A.; Trotta, F.; Caldera, F. Strategies to Develop Cyclodextrin-Based Nanosponges for Smart Drug Delivery. Smart Drug Delivery; IntechOpen, 2022. doi:10.5772/intechopen.100182
  • Hoti, G.; Matencio, A.; Rubin Pedrazzo, A.; Cecone, C.; Appleton, S. L.; Khazaei Monfared, Y.; Caldera, F.; Trotta, F. Nutraceutical Concepts and Dextrin-Based Delivery Systems. International journal of molecular sciences 2022, 23, 4102. doi:10.3390/ijms23084102
  • Utzeri, G.; Matias, P. M. C.; Murtinho, D.; Valente, A. J. M. Cyclodextrin-Based Nanosponges: Overview and Opportunities. Frontiers in chemistry 2022, 10, 859406. doi:10.3389/fchem.2022.859406
  • Mullick, P.; R Hegde, A.; Gopalan, D.; Pandey, A.; Nandakumar, K.; Jain, S.; Kuppusamy, G.; Mutalik, S. Evolving Era of "Sponges": Nanosponges as a Versatile Nanocarrier for the Effective Skin Delivery of Drugs. Current pharmaceutical design 2022, 28, 1885–1896. doi:10.2174/1381612828666220518090431
  • Pivato, R. V.; Rossi, F.; Ferro, M.; Castiglione, F.; Trotta, F.; Mele, A. β-Cyclodextrin Nanosponge Hydrogels as Drug Delivery Nanoarchitectonics for Multistep Drug Release Kinetics. ACS Applied Polymer Materials 2021, 3, 6562–6571. doi:10.1021/acsapm.1c01262
  • Rossi, B.; Tortora, M.; Catalini, S.; Gessini, A.; Masciovecchio, C. doi:10.1002/9783527830312.ch7
  • Appleton, S. L.; Navarro-Orcajada, S.; Martínez-Navarro, F. J.; Caldera, F.; López-Nicolás, J. M.; Trotta, F.; Matencio, A. Cyclodextrins as Anti-inflammatory Agents: Basis, Drugs and Perspectives. Biomolecules 2021, 11, 1384. doi:10.3390/biom11091384
  • Nazerdeylami, S.; Ghasemi, J. B.; Ziarani, G. M.; Amiri, A.; Badiei, A. Direct monitoring of diclofenac using a supramolecular fluorescent approach based on β-cyclodextrin nanosponge. Journal of Molecular Liquids 2021, 336, 116104. doi:10.1016/j.molliq.2021.116104
  • Di Meo, C.; Coviello, T.; Matricardi, P.; Lamanna, R. Anomalous enhanced water diffusion in polysaccharide interpenetrating hydrogels. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2021, 613, 125892. doi:10.1016/j.colsurfa.2020.125892
  • Khalid, Q.; Ahmad, M.; Minhas, M. U.; Batool, F.; Malik, N. S.; Rehman, M. Novel β-cyclodextrin nanosponges by chain growth condensation for solubility enhancement of dexibuprofen: Characterization and acute oral toxicity studies. Journal of Drug Delivery Science and Technology 2021, 61, 102089. doi:10.1016/j.jddst.2020.102089
  • Hoti, G.; Caldera, F.; Cecone, C.; Pedrazzo, A. R.; Anceschi, A.; Appleton, S. L.; Monfared, Y. K.; Trotta, F. Effect of the Cross-Linking Density on the Swelling and Rheological Behavior of Ester-Bridged β-Cyclodextrin Nanosponges. Materials (Basel, Switzerland) 2021, 14, 478. doi:10.3390/ma14030478
  • Tannous, M.; Caldera, F.; Hoti, G.; Dianzani, U.; Cavalli, R.; Trotta, F. Drug-Encapsulated Cyclodextrin Nanosponges. Methods in molecular biology (Clifton, N.J.) 2020, 2207, 247–283. doi:10.1007/978-1-0716-0920-0_19
  • Castiglione, F.; Saielli, G.; Mauri, M.; Simonutti, R.; Mele, A. Xenon Dynamics in Ionic Liquids: A Combined NMR and MD Simulation Study. The journal of physical chemistry. B 2020, 124, 6617–6627. doi:10.1021/acs.jpcb.0c03357


  • ZHANG XIAOJIN; ZHANG KAI; DAI YU; XIA FAN. Cyclodextrin-based adsorption material as well as preparation method and application thereof. CN 114602434 A, June 10, 2022.
Other Beilstein-Institut Open Science Activities