Deoxygenative gem-difluoroolefination of carbonyl compounds with (chlorodifluoromethyl)trimethylsilane and triphenylphosphine

Fei Wang, Lingchun Li, Chuanfa Ni and Jinbo Hu

Beilstein J. Org. Chem. 2014, 10, 344–351. https://doi.org/10.3762/bjoc.10.32

Supporting Information

Full experimental details (difluoromethylation of O, S, and N-nucleophiles and gem-difluoroolefination of carbonyl compounds with TMSCF2Cl) and compound characterization data are given.

Supporting Information File 1: Experimental procedures and characterization data.
Format: PDF Size: 609.7 KB Download

References

Article Citation
Download RIS (Reference Manager) Download BIB (BIBTEX)
Cited References
Download RIS (Reference Manager) Download BIB (BIBTEX)
Back To Article

Article is part of the issue

Organo-fluorine chemistry III

David O'Hagan

Latest Articles

New cembrane-type diterpenoids with anti-inflammatory activity from the South China Sea soft coral Sinularia sp.

  1. Ye-Qing Du,
  2. Heng Li,
  3. Quan Xu,
  4. Wei Tang,
  5. Zai-Yong Zhang,
  6. Ming-Zhi Su,
  7. Xue-Ting Liu and
  8. Yue-Wei Guo
  • Full Research Paper
  • Published 09 Dec 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1696–1706, doi:10.3762/bjoc.18.180

Redox-active molecules as organocatalysts for selective oxidative transformations – an unperceived organocatalysis field

  1. Elena R. Lopat’eva,
  2. Igor B. Krylov,
  3. Dmitry A. Lapshin and
  4. Alexander O. Terent’ev
  • Perspective
  • Published 09 Dec 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1672–1695, doi:10.3762/bjoc.18.179

Navigating and expanding the roadmap of natural product genome mining tools

  1. Friederike Biermann,
  2. Sebastian L. Wenski and
  3. Eric J. N. Helfrich
  • Perspective
  • Published 06 Dec 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1656–1671, doi:10.3762/bjoc.18.178

A novel spirocyclic scaffold accessed via tandem Claisen rearrangement/intramolecular oxa-Michael addition

  1. Anastasia Vepreva,
  2. Alexander Yanovich,
  3. Dmitry Dar’in,
  4. Grigory Kantin,
  5. Alexander Bunev and
  6. Mikhail Krasavin
  • Full Research Paper
  • Published 06 Dec 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1649–1655, doi:10.3762/bjoc.18.177

Rhodium-catalyzed intramolecular reductive aldol-type cyclization: Application for the synthesis of a chiral necic acid lactone

  1. Motoyuki Isoda,
  2. Kazuyuki Sato,
  3. Kenta Kameda,
  4. Kana Wakabayashi,
  5. Ryota Sato,
  6. Hideki Minami,
  7. Yukiko Karuo,
  8. Atsushi Tarui,
  9. Kentaro Kawai and
  10. Masaaki Omote
  • Full Research Paper
  • Published 02 Dec 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1642–1648, doi:10.3762/bjoc.18.176

A novel bis-triazole scaffold accessed via two tandem [3 + 2] cycloaddition events including an uncatalyzed, room temperature azide–alkyne click reaction

  1. Ksenia Malkova,
  2. Andrey Bubyrev,
  3. Vasilisa Krivovicheva,
  4. Dmitry Dar’in,
  5. Alexander Bunev and
  6. Mikhail Krasavin
  • Letter
  • Published 02 Dec 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1636–1641, doi:10.3762/bjoc.18.175

Synthesis of (−)-halichonic acid and (−)-halichonic acid B

  1. Keith P. Reber and
  2. Emma L. Niner
  • Full Research Paper
  • Published 01 Dec 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1629–1635, doi:10.3762/bjoc.18.174

Synthetic study toward the diterpenoid aberrarone

  1. Liang Shi,
  2. Zhiyu Gao,
  3. Yiqing Li,
  4. Yuanhao Dai,
  5. Yu Liu,
  6. Lili Shi and
  7. Hong-Dong Hao
  • Letter
  • Published 30 Nov 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1625–1628, doi:10.3762/bjoc.18.173

A new route for the synthesis of 1-deazaguanine and 1-deazahypoxanthine

  1. Raphael Bereiter,
  2. Marco Oberlechner and
  3. Ronald Micura
  • Full Research Paper
  • Published 29 Nov 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1617–1624, doi:10.3762/bjoc.18.172

One-pot double annulations to confer diastereoselective spirooxindolepyrrolothiazoles

  1. Juan Lu,
  2. Bin Yao,
  3. Desheng Zhan,
  4. Zhuo Sun,
  5. Yun Ji and
  6. Xiaofeng Zhang
  • Full Research Paper
  • Published 28 Nov 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1607–1616, doi:10.3762/bjoc.18.171

Latest Articles

Latest Thematic Issues

Enzymes in biosynthesis

Jeroen S. Dickschat

New Show Issue

Molecular and macromolecular electrochemistry: synthesis, mechanism, and redox properties

Shinsuke Inagi and Mahito Atobe

2022 Show Issue

Cyclodextrins as building blocks for new materials

Sophie Fourmentin and Miriana Kfoury

New Call Show Issue

Total synthesis: an enabling science

Bastien Nay

New Call Show Issue

Mechanochemistry III

José G. Hernández and Lars Borchardt

2022 Show Issue

Platform and enabling technologies in organic synthesis

Philipp Heretsch and Andreas Kirschning

2021 Show Issue

Organophosphorus chemistry: from model to application

György Keglevich

2021 Call Show Issue

Organic TADF materials design

Eli Zysman-Colman

2021 Show Issue

Earth-abundant 3d metal catalysis

Lutz Ackermann

2021 Show Issue
Browse all Thematic Issues

Other Beilstein-Institut Open Science Activities

Logo
Logo
Logo
Logo

Keep Informed

RSS Feed

Subscribe to our Latest Articles RSS Feed.

Subscribe

Follow the Beilstein-Institut

LinkedIn

Twitter: @BeilsteinInst