Supporting Information
| Supporting Information File 1: General experimental information, experimental details on the synthesis of compounds 2–4 and 6; full characterization data as well as 1H/ 19F/ 13C NMR spectra of all products. | ||
| Format: PDF | Size: 4.2 MB | Download |
Cite the Following Article
Palladium-catalyzed Heck-type reaction of secondary trifluoromethylated alkyl bromides
Tao Fan, Wei-Dong Meng and Xingang Zhang
Beilstein J. Org. Chem. 2017, 13, 2610–2616.
https://doi.org/10.3762/bjoc.13.258
How to Cite
Fan, T.; Meng, W.-D.; Zhang, X. Beilstein J. Org. Chem. 2017, 13, 2610–2616. doi:10.3762/bjoc.13.258
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
| Picture with graphical abstract, title and authors for social media postings and presentations. | ||
| Format: PNG | Size: 113.1 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- van Leeuwen, P. W.; Cano, I.; Freixa, Z. Advances in catalysis using Xantphos-like ligands; simplicity goes a long way. Coordination Chemistry Reviews 2025, 537, 216636. doi:10.1016/j.ccr.2025.216636
- Zhang, Q.-Q.; Jin, R.-X.; Gao, Q.; Liu, P.; Zuo, Y.-W.; Lan, Q.; Wang, X.-S. Regioselective Nickel-Catalyzed Hydrotrifluoroalkylation of Alkynes to Construct Trisubstituted Allylic Trifluoromethyl Alkenes. Organic letters 2025, 27, 3765–3770. doi:10.1021/acs.orglett.5c00980
- Xu, Q.; Zhao, Y.; Liu, X.; Jin, N.; He, K.; Pan, F. Nickel‐Catalyzed Reductive Cross‐Coupling of α–Trifluoromethylated Alkyl Electrophiles and Allylic Sulfones. European Journal of Organic Chemistry 2024, 27. doi:10.1002/ejoc.202400986
- Zhao, G.; Li, W.; Zhang, J. Recent Advances in Palladium-Catalyzed Asymmetric Heck/Tsuji-Trost Reactions of 1,n-Dienes. Chemistry (Weinheim an der Bergstrasse, Germany) 2024, 30, e202400076. doi:10.1002/chem.202400076
- Santiago, T. G.; Palma, P.; Cámpora, J. A tale of two metals: The Mizoroki-Heck reaction as a guide to compare the chemical characters of nickel and palladium in catalysis. Advances in Organometallic Chemistry; Elsevier, 2024; pp 1–179. doi:10.1016/bs.adomc.2024.04.002
- Li, W.; Mao, T.; Yang, J.; Shang, M.; Li, X.; Wang, A.; Wang, P.; Zhao, L. Synthesis of Secondary Trifluoromethylated Alkyl Bromides with Further Conversion to Boronic Esters and Alcohols. Asian Journal of Organic Chemistry 2023, 12. doi:10.1002/ajoc.202300329
- Xie, W.; Liu, S.; Hammond, G. B.; Xu, B. Alkali metal salts-assisted coupling reaction between fluorinated benzyl electrophiles and alkenylboronic acids. New Journal of Chemistry 2022, 46, 19095–19099. doi:10.1039/d2nj04156a
- Guo, P.; Tao, M.; Xu, W.-W.; Wang, A.-J.; Li, W.; Yao, Q.; Tong, J.; He, C.-Y. Synthesis of Secondary Trifluoromethylated Alkyl Bromides Using 2-Bromo-3,3,3-trifluoropropene as a Radical Acceptor. Organic letters 2022, 24, 2143–2148. doi:10.1021/acs.orglett.2c00425
- Cheng, J.; Zhang, H.; Lv, J.; Zheng, J. Palladium-Catalyzed Intermolecular Dicarbofunctionalization of Unactivated Alkenes: Synthesis of Fluoroalkylated Heterocycles with All-Carbon Quaternary Centers. European Journal of Organic Chemistry 2021, 2022. doi:10.1002/ejoc.202101342
- Sun, X.; Dong, X.; Liu, H.; Liu, Y. Recent Progress in Palladium‐Catalyzed Radical Reactions. Advanced Synthesis & Catalysis 2021, 363, 1527–1558. doi:10.1002/adsc.202001315
- Pingjie, W.; Cheng, Z.; Wang, X.; Wu, J.; Wu, F. Copper-Catalyzed Three-Component Reactions of 2-Iodo-2,2-difluoroacetophenones, Alkynes, and Trimethylsilyl Cyanide. European Journal of Organic Chemistry 2021, 2021, 1420–1423. doi:10.1002/ejoc.202001650
- Liu, C.; Zhu, C.; Cai, Y.; Yang, Z.; Zeng, H.; Chen, F.; Jiang, H. Fluorohalogenation of gem‐Difluoroalkenes: Synthesis and Applications of α‐Trifluoromethyl Halides. Chemistry (Weinheim an der Bergstrasse, Germany) 2020, 26, 1953–1957. doi:10.1002/chem.201905445
- Israr, M.; Xiong, H.; Li, Y.; Bao, H. Copper(I)-Catalyzed Cyanoperfluoroalkylation of Alkynes. Organic letters 2019, 21, 7078–7083. doi:10.1021/acs.orglett.9b02648
- Muñoz-Molina, J. M.; Pérez, P. J. Ruthenium-Catalyzed Heck-Type Alkenylation of Alkyl Bromides. The Journal of organic chemistry 2019, 84, 8289–8296. doi:10.1021/acs.joc.9b00898
- Kurandina, D.; Chuentragool, P.; Gevorgyan, V. Transition-Metal-Catalyzed Alkyl Heck-Type Reactions. Synthesis 2019, 51, 985–1005. doi:10.1055/s-0037-1611659
- Yang, J.; Zhao, H.-W.; He, J.; Zhang, C.-P. Pd-Catalyzed Mizoroki-Heck Reactions Using Fluorine-Containing Agents as the Cross-Coupling Partners. Catalysts 2018, 8, 23. doi:10.3390/catal8010023