Fluorogenic PNA probes

Scholarly Works

• Nazzal, H.; Yavin, E. Fmoc Solid-Phase FIT-PNA Synthesis-Manual and Automated Methodologies. Methods in molecular biology (Clifton, N.J.) 2025, 2934, 189–207. doi:10.1007/978-1-0716-4578-9_14
• Ishii, K.; Shigeto, H.; Yamamura, S.; Imai, Y.; Ohtsuki, T.; Kitamatsu, M. Fluorescence detection of DNA with a single-base mismatch by a Tm-independent peptide nucleic acid (PNA) twin probe. Organic & biomolecular chemistry 2025, 23, 6557–6563. doi:10.1039/d5ob00873e
• Miyata, H.; Shigeto, H.; Ikeya, T.; Ashizawa, T.; Iizuka, A.; Kikuchi, Y.; Maeda, C.; Kanematsu, A.; Yamashita, K.; Urakami, K.; Shimoda, Y.; Nagashima, T.; Ohshima, K.; Ohde, Y.; Isaka, M.; Sugino, T.; Muramatsu, K.; Kenmotsu, H.; Takahashi, T.; Yamaguchi, K.; Kitamatsu, M.; Yamamura, S.; Akiyama, Y. Localization of epidermal growth factor receptor-mutations using PNA:DNA probes in clinical specimens from patients with non-small cell lung cancer. Scientific reports 2025, 15, 11314. doi:10.1038/s41598-025-95081-z
• Wierzba, A. J.; Richards, E. M.; Lennon, S. R.; Batey, R. T.; Palmer, A. E. Unveiling the promise of peptide nucleic acids as functional linkers for an RNA imaging platform. RSC chemical biology 2025, 6, 249–262. doi:10.1039/d4cb00274a
• Wierzba, A. J.; Richards, E. M.; Lennon, S. R.; Batey, R. T.; Palmer, A. E. Unveiling the Promise of Peptide Nucleic Acids as Functional Linkers for Riboglow RNA Imaging Platform. Cold Spring Harbor Laboratory 2024. doi:10.1101/2024.10.03.616516
• Vazquez Bucheli, J. E.; Lee, Y.; Kim, B.; Azevedo, N. F.; Azevedo, A. S.; Todorov, S. D.; Ji, Y.; Kang, H.; Holzapfel, W. H. Use of FISH-FLOW as a Method for the Identification and Quantification of Bacterial Populations. Molecular nutrition & food research 2024, 69, e2400494. doi:10.1002/mnfr.202400494
• Mannully, S. T.; Mahajna, R.; Nazzal, H.; Maree, S.; Zheng, H.; Appella, D. H.; Reich, R.; Yavin, E. Detecting the FLJ22447 lncRNA in Ovarian Cancer with Cyclopentane-Modified FIT-PNAs (cpFIT-PNAs). Biomolecules 2024, 14, 609. doi:10.3390/biom14060609
• Sun, M.; Zhang, C.; Lu, S.; Mahmood, S.; Wang, J.; Sun, C.; Pang, J.; Han, L.; Liu, H. Recent Advances in Graphene Field‐Effect Transistor Toward Biological Detection. Advanced Functional Materials 2024, 34. doi:10.1002/adfm.202405471
• Tepper, O.; Appella, D. H.; Zheng, H.; Dzikowski, R.; Yavin, E. A Biotinylated cpFIT-PNA Platform for the Facile Detection of Drug Resistance to Artemisinin in Plasmodium falciparum. ACS sensors 2024, 9, 1458–1464. doi:10.1021/acssensors.3c02553
• Katkevics, M.; MacKay, J. A.; Rozners, E. Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs. Chemical communications (Cambridge, England) 2024, 60, 1999–2008. doi:10.1039/d3cc05409h
• Alavijeh, N. S.; Serrano, A.; Peters, M. S.; Wölper, C.; Schrader, T. Design and Synthesis of Artificial Nucleobases for Sequence-Selective DNA Recognition within the Major Groove. Chemistry, an Asian journal 2023, 18, e202300637. doi:10.1002/asia.202300637
• Noppakuadrittidej, P.; Charlermroj, R.; Makornwattana, M.; Kaew-Amdee, S.; Waditee-Sirisattha, R.; Vilaivan, T.; Praneenararat, T.; Karoonuthaisiri, N. Development of peptide nucleic acid-based bead array technology for Bacillus cereus detection. Scientific reports 2023, 13, 12482. doi:10.1038/s41598-023-38877-1
• Shigeto, H.; Miyata, H.; Ashizawa, T.; Iizuka, A.; Kikuchi, Y.; Hozumi, C.; Maeda, C.; Yamaguchi, K.; Yamamura, S.; Akiyama, Y. Localization of EGFR Mutations in Non-small-cell Lung Cancer Tissues Using Mutation-specific PNA-DNA Probes. Cancer genomics & proteomics 2023, 20, 375–382. doi:10.21873/cgp.20389
• Liang, Y.; Willey, S.; Chung, Y.-C.; Lo, Y.-M.; Miao, S.; Rundell, S.; Tu, L.-C.; Bong, D. Intracellular RNA and DNA tracking by uridine-rich internal loop tagging with fluorogenic bPNA. Nature communications 2023, 14, 2987. doi:10.1038/s41467-023-38579-2
• Murayama, K.; Yamano, Y.; Asanuma, H. Functionalization of acyclic xenonucleic acid with modified nucleobases. Polymer Journal 2023, 55, 743–752. doi:10.1038/s41428-023-00776-7
• Chowdhury, M.; Hudson, R. H. E. Exploring Nucleobase Modifications in Oligonucleotide Analogues for Use as Environmentally Responsive Fluorophores and Beyond. Chemical record (New York, N.Y.) 2022, 23, e202200218. doi:10.1002/tcr.202200218
• Kulkarni, P.; Datta, D.; Ganesh, K. N. Gemdimethyl Peptide Nucleic Acids (α/β/γ-gdm-PNA): E/Z-Rotamers Influence the Selectivity in the Formation of Parallel/Antiparallel gdm-PNA:DNA/RNA Duplexes. ACS omega 2022, 7, 40558–40568. doi:10.1021/acsomega.2c05873
• Shiraj, A.; Ramabhadran, R. O.; Ganesh, K. N. Aza-PNA: Engineering E-Rotamer Selectivity Directed by Intramolecular H-bonding. Organic letters 2022, 24, 7421–7427. doi:10.1021/acs.orglett.2c02993
• Yin, P.; Yao, G.; Zou, T.; A, N.; Na, P.; Yang, W.; Wang, H.; Tan, W. Facile preparation of N, S co-doped carbon dots and their application to a novel off-on fluorescent probe for selective determination of Hg2+. Dyes and Pigments 2022, 206, 110668. doi:10.1016/j.dyepig.2022.110668
• Liang, Y.; Willey, S.; Chung, Y.-C.; Lo, Y.-M.; Miao, S.; Rundell, S.; Tu, L.-C.; Bong, D. Fluorogenic U-rich internal loop (FLURIL) tagging with bPNA enables intracellular RNA and DNA tracking. Cold Spring Harbor Laboratory 2022. doi:10.1101/2022.07.21.501035

Explore citations to this article at