Nucleic acid chemistry II

  1. editorImage
  1. Editor: Prof. Hans-Achim Wagenknecht
    Karlsruhe Institute of Technology


The organic chemistry and synthesis of nucleic acids allows introducing natural and artificial functional groups as well as probes, markers or other biologically active molecules into these types of biopolymers and their synthetic analogs. Thus, nucleic acid chemistry is of fundamental importance for the actual and future research in chemical biology. Moreover, besides its biological functions, DNA and RNA are considered as an increasingly important architecture and scaffold for two- and three-dimensional objects in material sciences and photochemistry. These are enough reasons to summarize and highlight the different aspects of nucleic acid chemistry by focused reviews that are written by leading experts in this research field.

  • Review
  • Published 12 Jul 2017

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Beilstein J. Org. Chem. 2017, 13, 1368–1387, doi:10.3762/bjoc.13.134

  • Review
  • Published 13 Dec 2017

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Beilstein J. Org. Chem. 2017, 13, 2671–2681, doi:10.3762/bjoc.13.265

Synthetic mRNA capping

  1. Fabian Muttach,
  2. Nils Muthmann and
  3. Andrea Rentmeister
  • Review
  • Published 20 Dec 2017

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Beilstein J. Org. Chem. 2017, 13, 2819–2832, doi:10.3762/bjoc.13.274

  • Review
  • Published 08 Jan 2018

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Beilstein J. Org. Chem. 2018, 14, 84–105, doi:10.3762/bjoc.14.5

Fluorescent nucleobase analogues for base–base FRET in nucleic acids: synthesis, photophysics and applications

  1. Mattias Bood,
  2. Sangamesh Sarangamath,
  3. Moa S. Wranne,
  4. Morten Grøtli and
  5. L. Marcus Wilhelmsson
  • Review
  • Published 10 Jan 2018

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Beilstein J. Org. Chem. 2018, 14, 114–129, doi:10.3762/bjoc.14.7

Fluorogenic PNA probes

  1. Tirayut Vilaivan
  • Review
  • Published 29 Jan 2018

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Beilstein J. Org. Chem. 2018, 14, 253–281, doi:10.3762/bjoc.14.17

  • Review
  • Published 13 Feb 2018

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Beilstein J. Org. Chem. 2018, 14, 397–406, doi:10.3762/bjoc.14.28

Stimuli-responsive oligonucleotides in prodrug-based approaches for gene silencing

  1. Françoise Debart,
  2. Christelle Dupouy and
  3. Jean-Jacques Vasseur
  • Review
  • Published 19 Feb 2018

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Beilstein J. Org. Chem. 2018, 14, 436–469, doi:10.3762/bjoc.14.32

Enzyme-free genetic copying of DNA and RNA sequences

  1. Marilyne Sosson and
  2. Clemens Richert
  • Review
  • Published 12 Mar 2018

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Beilstein J. Org. Chem. 2018, 14, 603–617, doi:10.3762/bjoc.14.47

  • Review
  • Published 05 Apr 2018

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Beilstein J. Org. Chem. 2018, 14, 772–785, doi:10.3762/bjoc.14.65

Phosphodiester models for cleavage of nucleic acids

  1. Satu Mikkola,
  2. Tuomas Lönnberg and
  3. Harri Lönnberg
  • Review
  • Published 10 Apr 2018

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Beilstein J. Org. Chem. 2018, 14, 803–837, doi:10.3762/bjoc.14.68

Mechanochemistry of nucleosides, nucleotides and related materials

  1. Olga Eguaogie,
  2. Joseph S. Vyle,
  3. Patrick F. Conlon,
  4. Manuela A. Gîlea and
  5. Yipei Liang
  • Review
  • Published 27 Apr 2018

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Beilstein J. Org. Chem. 2018, 14, 955–970, doi:10.3762/bjoc.14.81

  • Review
  • Published 16 May 2018

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Beilstein J. Org. Chem. 2018, 14, 1051–1086, doi:10.3762/bjoc.14.93

  • Review
  • Published 04 Jun 2018

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Beilstein J. Org. Chem. 2018, 14, 1293–1308, doi:10.3762/bjoc.14.111

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