Phosphodiester models for cleavage of nucleic acids

Scholarly Works

• Ryu, J.-H.; Zheng, W.; Yang, X.-H.; Elsaidi, H.; Diakur, J.; Wiebe, L. I. Synthesis and Preliminary Evaluation of an ASGPr-Targeted Polycationic β-Cyclodextrin Carrier for Nucleosides and Nucleotides. Pharmaceutics 2024, 16, 323. doi:10.3390/pharmaceutics16030323
• Nardi, A. N.; Olivieri, A.; D'Abramo, M.; Amadei, A. A Theoretical-Computational Study of Phosphodiester Bond Cleavage Kinetics as a Function of the Temperature. Chemphyschem : a European journal of chemical physics and physical chemistry 2024, e202300952. doi:10.1002/cphc.202300952
• Vezzoni, C. A.; Casnati, A.; Orlanducci, S.; Sansone, F.; Salvio, R. Enzyme Mimics Based on Guanidinocalix[4]arene/ Nanodiamond Hybrid Systems with Phosphodiesterase Activity. ChemCatChem 2024, 16. doi:10.1002/cctc.202301477
• Gull, M.; Feng, T.; Smith, B.; Calcul, L.; Pasek, M. A. Prebiotic Syntheses of Organophosphorus Compounds from Reduced Source of Phosphorus in Non-Aqueous Solvents. Life (Basel, Switzerland) 2023, 13, 2134. doi:10.3390/life13112134
• Ding, M.; Ding, S.; Du, D.; Wang, X.; Hu, X.; Guan, P.; Lyu, Z.; Lin, Y. Recent advances in electrochemical biosensors for the detection of Aβ42, a biomarker for Alzheimer disease diagnosis. TrAC Trends in Analytical Chemistry 2023, 164, 117087. doi:10.1016/j.trac.2023.117087
• Yoon, S.; Ollie, E.; York, D. M.; Piccirilli, J. A.; Harris, M. E. Rapid Kinetics of Pistol Ribozyme: Insights into Limits to RNA Catalysis. Biochemistry 2023, 62, 2079–2092. doi:10.1021/acs.biochem.3c00160
• Yang, T.; Yu, J.; Ahmed, T.; Nguyen, K.; Nie, F.; Zan, R.; Li, Z.; Han, P.; Shen, H.; Zhang, X.; Takayama, S.; Song, Y. Synthetic neutrophil extracellular traps dissect bactericidal contribution of NETs under regulation of α-1-antitrypsin. Science advances 2023, 9, eadf2445. doi:10.1126/sciadv.adf2445
• Genna, V.; Iglesias-Fernández, J.; Reyes-Fraile, L.; Villegas, N.; Guckian, K.; Seth, P.; Wan, B.; Cabrero, C.; Terrazas, M.; Brun-Heath, I.; González, C.; Sciabola, S.; Villalobos, A.; Orozco, M. Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides. Nucleic acids research 2023, 51, 4713–4725. doi:10.1093/nar/gkad309
• Kundu, S.; Saha, S.; Panda, S. J.; Purohit, C. S.; Biswas, B. Tailor-made isostructural copper(ii) and nickel(ii) complexes with a newly designed (N,N)-donor scaffold as functional mimics of alkaline phosphatase. New Journal of Chemistry 2023, 47, 5894–5902. doi:10.1039/d2nj06127a
• Egli, M.; Manoharan, M. Chemistry, structure and function of approved oligonucleotide therapeutics. Nucleic acids research 2023, 51, 2529–2573. doi:10.1093/nar/gkad067
• El Orche, F.-E.; Hollenstein, M.; Houdaigoui, S.; Naccache, D.; Pchelina, D.; Rønne, P. B.; Ryan, P. Y. A.; Weibel, J.; Weil, R. Taphonomical Security: DNA Information with a Foreseeable Lifespan. Lecture Notes in Networks and Systems; Springer Nature Switzerland, 2023; pp 674–694. doi:10.1007/978-3-031-28073-3_46
• Nardi, A. N.; Olivieri, A.; Amadei, A.; Salvio, R.; D'Abramo, M. Modelling Complex Bimolecular Reactions in a Condensed Phase: The Case of Phosphodiester Hydrolysis. Molecules (Basel, Switzerland) 2023, 28, 2152. doi:10.3390/molecules28052152
• Zheng, Q.; Tian, C.; Zhang, Y.; Bai, M.; Liang, P.; Bian, Y. Studies on DNA fragmentation and cell integrity of rapidly hydroxyl radical inactivated Microcystis aeruginosa. Chemical Engineering Journal 2023, 454, 140414. doi:10.1016/j.cej.2022.140414
• Kaur, R.; Aboelnga, M. M.; Nikkel, D. J.; Wetmore, S. D. The metal dependence of single-metal mediated phosphodiester bond cleavage: a QM/MM study of a multifaceted human enzyme. Physical chemistry chemical physics : PCCP 2022, 24, 29130–29140. doi:10.1039/d2cp04338f
• Xu, S.; Del Pozo, J.; Romiti, F.; Fu, Y.; Mai, B. K.; Morrison, R. J.; Lee, K.; Hu, S.; Koh, M. J.; Lee, J.; Li, X.; Liu, P.; Hoveyda, A. H. Diastereo- and enantioselective synthesis of compounds with a trifluoromethyl- and fluoro-substituted carbon centre. Nature chemistry 2022, 14, 1459–1469. doi:10.1038/s41557-022-01054-4
• Lu, C.; Xu, Y.; Huang, P.-J. J.; Zandieh, M.; Wang, Y.; Zheng, J.; Liu, J. Protection of DNA by metal ions at 95 °C: from lower critical solution temperature (LCST) behavior to coordination-driven self-assembly. Nanoscale 2022, 14, 14613–14622. doi:10.1039/d2nr03461a
• Goldmeier, M. N.; Khononov, A.; Belakhov, V.; Pieńko, T.; Orbach, N.; Gilad Barzilay, Y.; Baasov, T. Dynamic Intramolecular Cap for Preserving Metallodrug Integrity─A Case of Catalytic Fluoroquinolones. Journal of medicinal chemistry 2022, 65, 14049–14065. doi:10.1021/acs.jmedchem.2c01302
• Mahato, C.; Menon, S.; Singh, A.; Afrose, S. P.; Mondal, J.; Das, D. Short peptide-based cross-β amyloids exploit dual residues for phosphoesterase like activity. Chemical science 2022, 13, 9225–9231. doi:10.1039/d2sc03205h
• Luiz, E.; Farias, G.; Bortoluzzi, A. J.; Neves, A.; de Melo Mattos, L. M.; Pereira, M. D.; Xavier, F. R.; Peralta, R. A. Hydrolytic activity of new bioinspired MnIIIMnII and FeIIIMnII complexes as mimetics of PAPs: Biological and environmental interest. Journal of inorganic biochemistry 2022, 236, 111965. doi:10.1016/j.jinorgbio.2022.111965
• Wang, L.; Hast, K.; Aggarwal, T.; Baci, M.; Hong, J.; Izgu, E. C. MicroRNA detection in biologically relevant media using a split aptamer platform. Bioorganic & medicinal chemistry 2022, 69, 116909. doi:10.1016/j.bmc.2022.116909

Explore citations to this article at