Recent advances on the transition-metal-catalyzed synthesis of imidazopyridines: an updated coverage

Gagandeep Kour Reen, Ashok Kumar and Pratibha Sharma
Beilstein J. Org. Chem. 2019, 15, 1612–1704. https://doi.org/10.3762/bjoc.15.165

Cite the Following Article

Recent advances on the transition-metal-catalyzed synthesis of imidazopyridines: an updated coverage
Gagandeep Kour Reen, Ashok Kumar and Pratibha Sharma
Beilstein J. Org. Chem. 2019, 15, 1612–1704. https://doi.org/10.3762/bjoc.15.165

How to Cite

Reen, G. K.; Kumar, A.; Sharma, P. Beilstein J. Org. Chem. 2019, 15, 1612–1704. doi:10.3762/bjoc.15.165

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 1.4 MB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Ren, H.; Wang, M.; Jiang, S.; Zhou, Y.; Lu, Z.; Xu, C.; Zhao, B. PIDA‐Enabled C3‐Amination of Imidazopyridines with Primary Aromatic Amines Using Rongalite as In Situ C1 Source. Asian Journal of Organic Chemistry 2025. doi:10.1002/ajoc.70189
  • Kumar, J.; Kumar, S.; Ali, S. M.; Rizvi, M. A.; Shah, B. A. Photoredox Mediated Synthesis of Substituted Imidazoles from Terminal Alkynes. Chemistry (Weinheim an der Bergstrasse, Germany) 2025, 31, e01097. doi:10.1002/chem.202501097
  • Kumari, A. H.; Ghosh, S.; Veeranagaiah, N. S.; Pallepogu, R.; Jannapu Reddy, R. Metal‐Free Four‐Component Strategy to Access Thioether‐Derived Imidazo[1,2‐a]pyridines and Imidazo[2,1‐b]thiazoles. European Journal of Organic Chemistry 2025, 28. doi:10.1002/ejoc.202500394
  • Wang, Y.; Huang, H.; Fang, X.; Ling, C.; Chen, T.; Yao, H.; Yan, Z. The sulfenylation of imidazopyridines with sulfinic acids mediated by DTBP/HCl. Results in Chemistry 2025, 16, 102428. doi:10.1016/j.rechem.2025.102428
  • Ansari, S.; Salamatmanesh, A.; Miraki, M. K.; Heydari, A. A copper bromide-decorated magnetic oyster shell biosupport as a sustainable catalyst for heterogeneous synthesis of imidazo[1,2- a ]pyridines in glycerol. Nanoscale Advances 2025. doi:10.1039/d5na00818b
  • Li, S. Recent Advances in the Electrochemical Functionalization of Imidazoheterocycles. Advanced Synthesis & Catalysis 2024, 366, 4908–4938. doi:10.1002/adsc.202401064
  • Pla, D.; Ferrer, M.; Gómez, M.; Martinez Lopez, M. Kinetico‐Mechanistic Studies of Cu(II)‐Mediated Cyclization of Imines via C−H Bond Activations. European Journal of Inorganic Chemistry 2024, 27. doi:10.1002/ejic.202400564
  • Nagy, E.; Máriás, A.; Kovács, M.; Skoda-Földes, R. Synthesis of 6- or 8-Carboxamido Derivatives of Imidazo[1,2-a]pyridines via a Heterogeneous Catalytic Aminocarbonylation Reaction. Molecules (Basel, Switzerland) 2024, 29, 5048. doi:10.3390/molecules29215048
  • Roscales, S.; Csáky, A. G. Metal‐Free Aminophosphonation: Eco‐Friendly Synthesis and Photophysical Properties of Fluorescent 3‐(Aminoimidazo[1,2‐a]Pyridin‐2‐yl)Phosphonates. Angewandte Chemie 2024, 136. doi:10.1002/ange.202412300
  • Roscales, S.; Csáky, A. G. Metal-Free Aminophosphonation: Eco-Friendly Synthesis and Photophysical Properties of Fluorescent 3-(Aminoimidazo[1,2-a]Pyridin-2-yl)Phosphonates. Angewandte Chemie (International ed. in English) 2024, 63, e202412300. doi:10.1002/anie.202412300
  • Gadekar, A. B.; Sonam; Shinde, V. N.; Bhawani; Rangan, K.; Kumar, A. Visible Light‐Driven Difluoroalkoxylation of Imidazopyridines Using N‐Fluorobenzenesulfonimide as Fluorinating Agent. Advanced Synthesis & Catalysis 2024, 366, 4794–4800. doi:10.1002/adsc.202400755
  • Maikhuri, V. K.; Mathur, D.; Chaudhary, A.; Kumar, R.; Parmar, V. S.; Singh, B. K. Transition-Metal Catalyzed Synthesis of Pyrimidines: Recent Advances, Mechanism, Scope and Future Perspectives. Topics in current chemistry (Cham) 2024, 382, 4. doi:10.1007/s41061-024-00451-2
  • Narayan, A.; Patel, S.; Baile, S. B.; Jain, S.; Sharma, S. Imidazo[1,2-A]Pyridine: Potent Biological Activity, SAR and Docking Investigations (2017-2022). Infectious disorders drug targets 2024, 24, e200324228067. doi:10.2174/0118715265274067240223040333
  • Benzenine, D.; Belhadj, F.; Kibou, Z.; Vázquez-Tato, M. P.; Seijas, J. A.; Choukchou-Braham, N. Green and Eco-Friendly Multicomponent Synthesis of 2-Hydroxypyridines Under Free Solvent Conditions. In 27th International Electronic Conference on Synthetic Organic Chemistry, MDPI, 2023; 109. doi:10.3390/ecsoc-27-16297
  • Kaur, P.; Gurjar, K. K.; Arora, T.; Bharti, D.; Kaur, M.; Kumar, V.; Parkash, J.; Kumar, R. Efficient synthesis and mechanistic insights for the formation of imidazo[1,2-a]pyridines via multicomponent decarboxylative coupling using chitosan-supported copper catalysts. Molecular Catalysis 2023, 550, 113582. doi:10.1016/j.mcat.2023.113582
  • Liu, X.; Guo, X.; Jiang, Z.; Li, C.; Nan, Z.; Liu, Y. Photocatalyzed intermolecular C–N bond formation for the synthesis of imidazo[1,2-a]pyridines. Tetrahedron Letters 2023, 129, 154746. doi:10.1016/j.tetlet.2023.154746
  • Meena, N.; Shinde, V. N.; Sonam; Swami, P. N.; Rangan, K.; Kumar, A. Catalyst-Controlled Regiodivergent Oxidative Annulation of 2-Arylimidazo[1,2-a]pyridines with Cinnamaldehyde Derivatives for Construction of Fused N-Heterocyclic Frameworks. The Journal of organic chemistry 2023, 88, 12902–12913. doi:10.1021/acs.joc.3c00717
  • Nikoshvili, L. Z.; Matveeva, V. G. Recent Progress in Pd-Catalyzed Tandem Processes. Catalysts 2023, 13, 1213. doi:10.3390/catal13081213
  • Vchislo, N. V.; Fedoseeva, V. G.; Verochkina, E. A. The Reactions of p-Tosylmethyl Isocyanide with Aldehydes in the Synthesis of Heterocyclic Compounds: A Review. Mini-Reviews in Organic Chemistry 2023, 20, 372–393. doi:10.2174/1570193x19999220523113243
  • Sakhuja, R.; Kumar, A. doi:10.1002/9781119774167.ch11
Other Beilstein-Institut Open Science Activities