Lipophilicity trends upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl groups

Benjamin Jeffries, Zhong Wang, Robert I. Troup, Anaïs Goupille, Jean-Yves Le Questel, Charlene Fallan, James S. Scott, Elisabetta Chiarparin, Jérôme Graton and Bruno Linclau

Beilstein J. Org. Chem. 2020, 16, 2141–2150. https://doi.org/10.3762/bjoc.16.182

Supporting Information

Supporting Information File 1: Synthesis, characterisation and copies of spectra of the novel compounds, details of the calculations, logP determinations of the nonfluorinated parents E1 and F1, and experimental measurements of the lipophilicities of the fluorinated derivatives.
Format: PDF Size: 2.3 MB Download

References

Article Citation
Download RIS (Reference Manager) Download BIB (BIBTEX)
Cited References
Download RIS (Reference Manager) Download BIB (BIBTEX)

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.

Format: PNG Size: 9.9 MB Download
Back To Article

Article is part of the issue

Organo-fluorine chemistry V

David O'Hagan

Latest Articles

First example of organocatalysis by cathodic N-heterocyclic carbene generation and accumulation using a divided electrochemical flow cell

  1. Daniele Rocco,
  2. Ana A. Folgueiras-Amador,
  3. Richard C. D. Brown and
  4. Marta Feroci
  • Full Research Paper
  • Published 05 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 979–990, doi:10.3762/bjoc.18.98

Understanding the competing pathways leading to hydropyrene and isoelisabethatriene

  1. Shani Zev,
  2. Marion Ringel,
  3. Ronja Driller,
  4. Bernhard Loll,
  5. Thomas Brück and
  6. Dan T. Major
  • Full Research Paper
  • Published 04 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 972–978, doi:10.3762/bjoc.18.97

Electrochemical and spectroscopic properties of twisted dibenzo[g,p]chrysene derivatives

  1. Tomoya Imai,
  2. Ryuhei Akasaka,
  3. Naruhiro Yoshida,
  4. Toru Amaya and
  5. Tetsuo Iwasawa
  • Full Research Paper
  • Published 03 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 963–971, doi:10.3762/bjoc.18.96

Electroreductive coupling of 2-acylbenzoates with α,β-unsaturated carbonyl compounds: density functional theory study on product selectivity

  1. Naoki Kise and
  2. Toshihiko Sakurai
  • Full Research Paper
  • Published 02 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 956–962, doi:10.3762/bjoc.18.95

Introducing a new 7-ring fused diindenone-dithieno[3,2-b:2',3'-d]thiophene unit as a promising component for organic semiconductor materials

  1. Valentin H. K. Fell,
  2. Joseph Cameron,
  3. Alexander L. Kanibolotsky,
  4. Eman J. Hussien and
  5. Peter J. Skabara
  • Full Research Paper
  • Published 01 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 944–955, doi:10.3762/bjoc.18.94

On Reuben G. Jones synthesis of 2-hydroxypyrazines

  1. Pierre Legrand and
  2. Yves L. Janin
  • Full Research Paper
  • Published 29 Jul 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 935–943, doi:10.3762/bjoc.18.93

Morita–Baylis–Hillman reaction of 3-formyl-9H-pyrido[3,4-b]indoles and fluorescence studies of the products

  1. Nisha Devi and
  2. Virender Singh
  • Full Research Paper
  • Published 26 Jul 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 926–934, doi:10.3762/bjoc.18.92

Anti-inflammatory aromadendrane- and cadinane-type sesquiterpenoids from the South China Sea sponge Acanthella cavernosa

  1. Shou-Mao Shen,
  2. Qing Yang,
  3. Yi Zang,
  4. Jia Li,
  5. Xueting Liu and
  6. Yue-Wei Guo
  • Full Research Paper
  • Published 25 Jul 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 916–925, doi:10.3762/bjoc.18.91

Synthetic strategies for the preparation of γ-phostams: 1,2-azaphospholidine 2-oxides and 1,2-azaphospholine 2-oxides

  1. Jiaxi Xu
  • Review
  • Published 22 Jul 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 889–915, doi:10.3762/bjoc.18.90

Efficient production of clerodane and ent-kaurane diterpenes through truncated artificial pathways in Escherichia coli

  1. Fang-Ru Li,
  2. Xiaoxu Lin,
  3. Qian Yang,
  4. Ning-Hua Tan and
  5. Liao-Bin Dong
  • Full Research Paper
  • Published 21 Jul 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 881–888, doi:10.3762/bjoc.18.89

Latest Articles

Latest Thematic Issues

Enzymes in biosynthesis

Jeroen S. Dickschat

New Show Issue

Molecular and macromolecular electrochemistry: synthesis, mechanism, and redox properties

Shinsuke Inagi and Mahito Atobe

New Show Issue

Mechanochemistry III

José G. Hernández and Lars Borchardt

New Show Issue

Platform and enabling technologies in organic synthesis

Philipp Heretsch and
Andreas Kirschning

2021 Show Issue

Organic TADF materials design

Eli Zysman-Colman

New Call Show Issue

Earth-abundant 3d metal catalysis

Lutz Ackermann

2021 Show Issue

Supramolecular approaches to mediate chemical reactivity

Carmine Gaeta, Pablo Ballester
and Qi-Qiang Wang

2021 Show Issue

New advances in asymmetric organocatalysis

Radovan Šebesta

2020 Show Issue

GlycoBioinformatics

Kiyoko F. Aoki-Kinoshita,
Frédérique Lisacek, Niclas Karlsson, 
Daniel Kolarich and Nicolle Packer

2020 Show Issue
Browse all Thematic Issues

Other Beilstein-Institut Open Science Activities

Logo
Logo
Logo
Logo

Keep Informed

RSS Feed

Subscribe to our Latest Articles RSS Feed.

Subscribe

Follow the Beilstein-Institut

LinkedIn

Twitter: @BeilsteinInst