The Groebke–Blackburn–Bienaymé reaction in its maturity: innovation and improvements since its 21st birthday (2019–2023)

Cristina Martini, Muhammad Idham Darussalam Mardjan and Andrea Basso
Beilstein J. Org. Chem. 2024, 20, 1839–1879. https://doi.org/10.3762/bjoc.20.162
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Structures extracted using BChemXtract (further structures may be extracted with future versions)
Structure with the molecular formula C<sub>4</sub>H<sub>8</sub>O<sub>3</sub>
Molecular Formula C4H8O3
Structure with the molecular formula C<sub>19</sub>H<sub>15</sub>NO
Molecular Formula C19H15NO
Structure with the molecular formula C<sub>17</sub>H<sub>19</sub>N<sub>5</sub>O<sub>2</sub>
Molecular Formula C17H19N5O2
Structure with the molecular formula C<sub>37</sub>H<sub>39</sub>Cl<sub>2</sub>N<sub>5</sub>O<sub>3</sub>
Molecular Formula C37H39Cl2N5O3
Structure with the molecular formula C<sub>21</sub>H<sub>19</sub>FN<sub>4</sub>
Molecular Formula C21H19FN4
Structure with the molecular formula C<sub>25</sub>H<sub>23</sub>N<sub>5</sub>O<sub>5</sub>S
Molecular Formula C25H23N5O5S
Structure with the molecular formula C<sub>24</sub>H<sub>22</sub>N<sub>6</sub>O<sub>5</sub>S
Molecular Formula C24H22N6O5S
Structure with the molecular formula [C<sub>12</sub>H<sub>10</sub>I]<sup>+</sup>
Molecular Formula [C12H10I]+
Structure with the molecular formula [C<sub>12</sub>H<sub>8</sub>I]<sup>+</sup>
Molecular Formula [C12H8I]+
Structure with the molecular formula C<sub>7</sub>H<sub>11</sub>N
Molecular Formula C7H11N
Structure with the molecular formula C<sub>18</sub>H<sub>14</sub>N<sub>4</sub>
Molecular Formula C18H14N4
Structure with the molecular formula C<sub>19</sub>H<sub>15</sub>N<sub>3</sub>S
Molecular Formula C19H15N3S
Structure with the molecular formula C<sub>23</sub>H<sub>21</sub>N<sub>5</sub>O<sub>5</sub>S<sub>2</sub>
Molecular Formula C23H21N5O5S2
Structure with the molecular formula C<sub>21</sub>H<sub>21</sub>N<sub>5</sub>O
Molecular Formula C21H21N5O
Structure with the molecular formula C<sub>8</sub>H<sub>5</sub>NO<sub>2</sub>
Molecular Formula C8H5NO2
Structure with the molecular formula C<sub>6</sub>H<sub>11</sub>N
Molecular Formula C6H11N
Structure with the molecular formula C<sub>19</sub>H<sub>19</sub>N<sub>3</sub>O<sub>2</sub>
Molecular Formula C19H19N3O2
Structure with the molecular formula C<sub>21</sub>H<sub>25</sub>N<sub>5</sub>
Molecular Formula C21H25N5
Structure with the molecular formula C<sub>7</sub>H<sub>7</sub>N<sub>3</sub>
Molecular Formula C7H7N3
Structure with the molecular formula C<sub>6</sub>H<sub>7</sub>BO<sub>2</sub>
Molecular Formula C6H7BO2
Structure with the molecular formula C<sub>23</sub>H<sub>23</sub>N<sub>3</sub>
Molecular Formula C23H23N3
Structure with the molecular formula C<sub>17</sub>H<sub>19</sub>N<sub>5</sub>
Molecular Formula C17H19N5
Structure with the molecular formula C<sub>18</sub>H<sub>15</sub>N<sub>5</sub>
Molecular Formula C18H15N5
Structure with the molecular formula C<sub>30</sub>H<sub>30</sub>N<sub>4</sub>O
Molecular Formula C30H30N4O
Structure with the molecular formula C<sub>5</sub>H<sub>5</sub>BrN<sub>2</sub>
Molecular Formula C5H5BrN2
Structure with the molecular formula C<sub>17</sub>H<sub>18</sub>BrN<sub>3</sub>
Molecular Formula C17H18BrN3
Structure with the molecular formula C<sub>6</sub>H<sub>6</sub>O<sub>3</sub>
Molecular Formula C6H6O3
Structure with the molecular formula C<sub>21</sub>H<sub>16</sub>N<sub>4</sub>
Molecular Formula C21H16N4
Structure with the molecular formula C<sub>20</sub>H<sub>14</sub>N<sub>4</sub>
Molecular Formula C20H14N4
Structure with the molecular formula C<sub>3</sub>H<sub>4</sub>N<sub>2</sub>S
Molecular Formula C3H4N2S
Structure with the molecular formula C<sub>14</sub>H<sub>17</sub>N<sub>3</sub>O<sub>2</sub>S
Molecular Formula C14H17N3O2S
Structure with the molecular formula C<sub>35</sub>H<sub>36</sub>O<sub>6</sub>
Molecular Formula C35H36O6
Structure with the molecular formula C<sub>47</sub>H<sub>51</sub>N<sub>3</sub>O<sub>5</sub>
Molecular Formula C47H51N3O5
Structure with the molecular formula C<sub>32</sub>H<sub>32</sub>N<sub>4</sub>O<sub>3</sub>
Molecular Formula C32H32N4O3
Structure with the molecular formula C<sub>21</sub>H<sub>15</sub>N<sub>3</sub>O<sub>4</sub>
Molecular Formula C21H15N3O4
Structure with the molecular formula C<sub>41</sub>H<sub>28</sub>N<sub>8</sub>O<sub>2</sub>
Molecular Formula C41H28N8O2
Structure with the molecular formula C<sub>19</sub>H<sub>27</sub>N<sub>3</sub>O<sub>5</sub>
Molecular Formula C19H27N3O5
Structure with the molecular formula C<sub>26</sub>H<sub>19</sub>N<sub>3</sub>O<sub>2</sub>
Molecular Formula C26H19N3O2
Structure with the molecular formula C<sub>23</sub>H<sub>32</sub>O<sub>4</sub>
Molecular Formula C23H32O4
Structure with the molecular formula C<sub>19</sub>H<sub>14</sub>N<sub>4</sub>O<sub>3</sub>
Molecular Formula C19H14N4O3
Structure with the molecular formula C<sub>41</sub>H<sub>31</sub>N<sub>5</sub>O<sub>3</sub>
Molecular Formula C41H31N5O3
Structure with the molecular formula C<sub>22</sub>H<sub>32</sub>O<sub>3</sub>
Molecular Formula C22H32O3
Structure with the molecular formula C<sub>17</sub>H<sub>16</sub>O
Molecular Formula C17H16O
Structure with the molecular formula C<sub>19</sub>H<sub>14</sub>N<sub>4</sub>O<sub>2</sub>
Molecular Formula C19H14N4O2
Structure with the molecular formula C<sub>11</sub>H<sub>12</sub>O<sub>3</sub>
Molecular Formula C11H12O3
Structure with the molecular formula C<sub>4</sub>H<sub>5</sub>N<sub>3</sub>
Molecular Formula C4H5N3
Structure with the molecular formula C<sub>4</sub>H<sub>9</sub>NSi
Molecular Formula C4H9NSi
Structure with the molecular formula C<sub>4</sub>H<sub>4</sub>N<sub>4</sub>
Molecular Formula C4H4N4
Structure with the molecular formula C<sub>24</sub>H<sub>24</sub>FN<sub>5</sub>O
Molecular Formula C24H24FN5O
Structure with the molecular formula C<sub>27</sub>H<sub>22</sub>F<sub>3</sub>N<sub>7</sub>O
Molecular Formula C27H22F3N7O
Structure with the molecular formula C<sub>11</sub>H<sub>13</sub>NO<sub>2</sub>
Molecular Formula C11H13NO2
Structure with the molecular formula C<sub>5</sub>H<sub>7</sub>NO<sub>2</sub>
Molecular Formula C5H7NO2
Structure with the molecular formula C<sub>9</sub>H<sub>7</sub>NO
Molecular Formula C9H7NO
Structure with the molecular formula C<sub>9</sub>H<sub>6</sub>O
Molecular Formula C9H6O
Structure with the molecular formula C<sub>20</sub>H<sub>18</sub>F<sub>3</sub>N<sub>5</sub>O
Molecular Formula C20H18F3N5O
Structure with the molecular formula C<sub>14</sub>H<sub>20</sub>N<sub>2</sub>O<sub>3</sub>
Molecular Formula C14H20N2O3
Structure with the molecular formula C<sub>21</sub>H<sub>22</sub>N<sub>2</sub>
Molecular Formula C21H22N2
Structure with the molecular formula C<sub>14</sub>H<sub>10</sub>O<sub>3</sub>
Molecular Formula C14H10O3
Structure with the molecular formula C<sub>8</sub>H<sub>6</sub>O<sub>2</sub>
Molecular Formula C8H6O2
Structure with the molecular formula C<sub>15</sub>H<sub>13</sub>FN<sub>4</sub>O<sub>2</sub>
Molecular Formula C15H13FN4O2
Structure with the molecular formula C<sub>17</sub>H<sub>18</sub>N<sub>4</sub>O<sub>2</sub>
Molecular Formula C17H18N4O2
Structure with the molecular formula C<sub>38</sub>H<sub>36</sub>N<sub>6</sub>O<sub>2</sub>
Molecular Formula C38H36N6O2
Structure with the molecular formula C<sub>10</sub>H<sub>8</sub>N<sub>2</sub>
Molecular Formula C10H8N2
Structure with the molecular formula C<sub>27</sub>H<sub>15</sub>F<sub>3</sub>O<sub>3</sub>
Molecular Formula C27H15F3O3
Structure with the molecular formula C<sub>17</sub>H<sub>17</sub>FN<sub>4</sub>O<sub>2</sub>
Molecular Formula C17H17FN4O2
Structure with the molecular formula C<sub>49</sub>H<sub>50</sub>N<sub>6</sub>O<sub>2</sub>
Molecular Formula C49H50N6O2
Structure with the molecular formula C<sub>7</sub>H<sub>6</sub>O
Molecular Formula C7H6O
Structure with the molecular formula C<sub>27</sub>H<sub>15</sub>N<sub>3</sub>
Molecular Formula C27H15N3
Structure with the molecular formula C<sub>8</sub>H<sub>4</sub>N<sub>2</sub>
Molecular Formula C8H4N2
Structure with the molecular formula C<sub>5</sub>H<sub>6</sub>N<sub>2</sub>
Molecular Formula C5H6N2
Structure with the molecular formula C<sub>5</sub>H<sub>9</sub>N
Molecular Formula C5H9N
Structure with the molecular formula C<sub>5</sub>H<sub>6</sub>N<sub>4</sub>S
Molecular Formula C5H6N4S
Structure with the molecular formula C<sub>9</sub>H<sub>8</sub>O<sub>4</sub>
Molecular Formula C9H8O4
Structure with the molecular formula C<sub>5</sub>H<sub>5</sub>ClN<sub>2</sub>
Molecular Formula C5H5ClN2
Structure with the molecular formula C<sub>10</sub>H<sub>8</sub>O<sub>2</sub>
Molecular Formula C10H8O2
Structure with the molecular formula C<sub>7</sub>H<sub>7</sub>N<sub>3</sub>
Molecular Formula C7H7N3
Structure with the molecular formula C<sub>17</sub>H<sub>19</sub>N<sub>5</sub>S
Molecular Formula C17H19N5S
Structure with the molecular formula C<sub>4</sub>H<sub>6</sub>N<sub>2</sub>
Molecular Formula C4H6N2
Structure with the molecular formula C<sub>4</sub>H<sub>8</sub>O<sub>3</sub>S
Molecular Formula C4H8O3S
Structure with the molecular formula C<sub>9</sub>H<sub>17</sub>N
Molecular Formula C9H17N
Structure with the molecular formula C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>
Molecular Formula C7H6O2
Structure with the molecular formula C<sub>14</sub>H<sub>10</sub>N<sub>2</sub>O<sub>6</sub>S<sub>2</sub>
Molecular Formula C14H10N2O6S2
Structure with the molecular formula C<sub>25</sub>H<sub>23</sub>N<sub>5</sub>O<sub>5</sub>S
Molecular Formula C25H23N5O5S
Structure with the molecular formula [C<sub>8</sub>H<sub>15</sub>N<sub>2</sub>O<sub>3</sub>S]<sup>+</sup>
Molecular Formula [C8H15N2O3S]+
Structure with the molecular formula C<sub>8</sub>H<sub>8</sub>O
Molecular Formula C8H8O
Structure with the molecular formula C<sub>20</sub>H<sub>23</sub>N<sub>3</sub>
Molecular Formula C20H23N3
Structure with the molecular formula C<sub>17</sub>H<sub>19</sub>N<sub>3</sub>O
Molecular Formula C17H19N3O
Structure with the molecular formula C<sub>14</sub>H<sub>18</sub>N<sub>4</sub>O<sub>3</sub>
Molecular Formula C14H18N4O3
Structure with the molecular formula C<sub>30</sub>H<sub>30</sub>O<sub>8</sub>
Molecular Formula C30H30O8
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