Stereoselective, nitro-Mannich/lactamisation cascades for the direct synthesis of heavily decorated 5-nitropiperidin-2-ones and related heterocycles

Pavol Jakubec, Dane M. Cockfield, Madeleine Helliwell, James Raftery and Darren J. Dixon

Beilstein J. Org. Chem. 2012, 8, 567–578. doi:10.3762/bjoc.8.64

Supporting Information

Supporting Information File 1: General experimental, copies of 1H and 13C NMR spectra for all new compounds (1a–j, 2a, 2a’’, 2m, 2m’, 6b–e, 10a–d, 11a–c, 12a,b).
Format: PDF Size: 5.5 MB Download
Supporting Information File 2: X-ray crystal structure of compound 2m’.
Format: CIF Size: 23.2 KB Download
Supporting Information File 3: X-ray crystal structures of compounds 1g, 2, 2a’’, 6e and 11c.
Format: CIF Size: 97.7 KB Download
Back To Article

Article is part of the issue

Benjamin List

Latest Articles

Asymmetric organocatalyzed synthesis of coumarin derivatives

  1. Natália M. Moreira,
  2. Lorena S. R. Martelli and
  3. Arlene G. Corrêa
  • Review
  • Published 03 Aug 2021

Beilstein J. Org. Chem. 2021, 17, 1952–1980, doi:10.3762/bjoc.17.128

Beilstein J. Org. Chem. 2021, 17, 1939–1951, doi:10.3762/bjoc.17.127

On the application of 3d metals for C–H activation toward bioactive compounds: The key step for the synthesis of silver bullets

  1. Renato L. Carvalho,
  2. Amanda S. de Miranda,
  3. Mateus P. Nunes,
  4. Roberto S. Gomes,
  5. Guilherme A. M. Jardim and
  6. Eufrânio N. da Silva Júnior
  • Review
  • Published 30 Jul 2021

Beilstein J. Org. Chem. 2021, 17, 1849–1938, doi:10.3762/bjoc.17.126

Beilstein J. Org. Chem. 2021, 17, 1828–1848, doi:10.3762/bjoc.17.125

  • Review
  • Published 28 Jul 2021

Beilstein J. Org. Chem. 2021, 17, 1814–1827, doi:10.3762/bjoc.17.124

  • Review
  • Published 27 Jul 2021

Beilstein J. Org. Chem. 2021, 17, 1752–1813, doi:10.3762/bjoc.17.123

Beilstein J. Org. Chem. 2021, 17, 1733–1751, doi:10.3762/bjoc.17.122

Cerium-photocatalyzed aerobic oxidation of benzylic alcohols to aldehydes and ketones

  1. Girish Suresh Yedase,
  2. Sumit Kumar,
  3. Jessica Stahl,
  4. Burkhard König and
  5. Veera Reddy Yatham
  • Letter
  • Published 23 Jul 2021

Beilstein J. Org. Chem. 2021, 17, 1727–1732, doi:10.3762/bjoc.17.121

Correction: Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes

  1. Audrey Gilbert,
  2. Pauline Langowski,
  3. Marine Delgado,
  4. Laurent Chabaud,
  5. Mathieu Pucheault and
  6. Jean-François Paquin
  • Correction
  • Published 23 Jul 2021

Beilstein J. Org. Chem. 2021, 17, 1725–1726, doi:10.3762/bjoc.17.120

Beilstein J. Org. Chem. 2021, 17, 1712–1724, doi:10.3762/bjoc.17.119

Latest Thematic Issues


Kiyoko F. Aoki-Kinoshita, Frédérique Lisacek, Niclas Karlsson, Daniel Kolarich, and Nicolle Packer

Molecular recognition

Jochen Niemeyer, Thomas Schrader and Ivo Piantanida

2020 Show Issue

Chemical ecology

Christine Beemelmanns

New Call Show Issue

Green chemistry II

Luigi Vaccaro

2019 Show Issue

Other Beilstein-Institut Open Science Activities

Keep Informed

RSS Feed

Subscribe to our Latest Articles RSS Feed.


Follow the Beilstein-Institut


Twitter: @BeilsteinInst