Stereoselective, nitro-Mannich/lactamisation cascades for the direct synthesis of heavily decorated 5-nitropiperidin-2-ones and related heterocycles

Pavol Jakubec, Dane M. Cockfield, Madeleine Helliwell, James Raftery and Darren J. Dixon

Beilstein J. Org. Chem. 2012, 8, 567–578. doi:10.3762/bjoc.8.64

Supporting Information

Supporting Information File 1: General experimental, copies of 1H and 13C NMR spectra for all new compounds (1a–j, 2a, 2a’’, 2m, 2m’, 6b–e, 10a–d, 11a–c, 12a,b).
Format: PDF Size: 5.5 MB Download
Supporting Information File 2: X-ray crystal structure of compound 2m’.
Format: CIF Size: 23.2 KB Download
Supporting Information File 3: X-ray crystal structures of compounds 1g, 2, 2a’’, 6e and 11c.
Format: CIF Size: 97.7 KB Download
Back To Article

Article is part of the issue

Benjamin List

Latest Articles

  • Review
  • Published 18 May 2021

Beilstein J. Org. Chem. 2021, 17, 1181–1312, doi:10.3762/bjoc.17.90

  • Full Research Paper
  • Published 17 May 2021

Beilstein J. Org. Chem. 2021, 17, 1171–1180, doi:10.3762/bjoc.17.89

Structural effects of meso-halogenation on porphyrins

  1. Keith J. Flanagan,
  2. Maximilian Paradiz Dominguez,
  3. Zoi Melissari,
  4. Hans-Georg Eckhardt,
  5. René M. Williams,
  6. Dáire Gibbons,
  7. Caroline Prior,
  8. Gemma M. Locke,
  9. Alina Meindl,
  10. Aoife A. Ryan and
  11. Mathias O. Senge
  • Full Research Paper
  • Published 14 May 2021

Beilstein J. Org. Chem. 2021, 17, 1149–1170, doi:10.3762/bjoc.17.88

  • Full Research Paper
  • Published 14 May 2021

Beilstein J. Org. Chem. 2021, 17, 1141–1148, doi:10.3762/bjoc.17.87

N-tert-Butanesulfinyl imines in the asymmetric synthesis of nitrogen-containing heterocycles

  1. Joseane A. Mendes,
  2. Paulo R. R. Costa,
  3. Miguel Yus,
  4. Francisco Foubelo and
  5. Camilla D. Buarque
  • Review
  • Published 12 May 2021

Beilstein J. Org. Chem. 2021, 17, 1096–1140, doi:10.3762/bjoc.17.86

Synthesis of multiply fluorinated N-acetyl-D-glucosamine and D-galactosamine analogs via the corresponding deoxyfluorinated glucosazide and galactosazide phenyl thioglycosides

  1. Vojtěch Hamala,
  2. Lucie Červenková Šťastná,
  3. Martin Kurfiřt,
  4. Petra Cuřínová,
  5. Martin Dračínský and
  6. Jindřich Karban
  • Full Research Paper
  • Published 11 May 2021

Beilstein J. Org. Chem. 2021, 17, 1086–1095, doi:10.3762/bjoc.17.85

Recent advances in palladium-catalysed asymmetric 1,4–additions of arylboronic acids to conjugated enones and chromones

  1. Jan Bartáček,
  2. Jan Svoboda,
  3. Martin Kocúrik,
  4. Jaroslav Pochobradský,
  5. Alexander Čegan,
  6. Miloš Sedlák and
  7. Jiří Váňa
  • Review
  • Published 10 May 2021

Beilstein J. Org. Chem. 2021, 17, 1048–1085, doi:10.3762/bjoc.17.84

Nitroalkene reduction in deep eutectic solvents promoted by BH3NH3

  1. Chiara Faverio,
  2. Monica Fiorenza Boselli,
  3. Patricia Camarero Gonzalez,
  4. Alessandra Puglisi and
  5. Maurizio Benaglia
  • Letter
  • Published 06 May 2021

Beilstein J. Org. Chem. 2021, 17, 1041–1047, doi:10.3762/bjoc.17.83

Synthetic accesses to biguanide compounds

  1. Oleksandr Grytsai,
  2. Cyril Ronco and
  3. Rachid Benhida
  • Review
  • Published 05 May 2021

Beilstein J. Org. Chem. 2021, 17, 1001–1040, doi:10.3762/bjoc.17.82

  • Full Research Paper
  • Published 04 May 2021

Beilstein J. Org. Chem. 2021, 17, 991–1000, doi:10.3762/bjoc.17.81

Latest Thematic Issues

GlycoBioinformatics


Kiyoko F. Aoki-Kinoshita, Frédérique Lisacek, Niclas Karlsson, Daniel Kolarich, and Nicolle Packer

2020 Show Issue

Molecular recognition


Jochen Niemeyer, Thomas Schrader and Ivo Piantanida

2020 Show Issue

Green chemistry II


Luigi Vaccaro

Copper-catalyzed reactions for organic synthesis


Gwilherm Evano and Olivier Riant

2019 Show Issue

Molecular switches


Wiktor Szymanski and Stefan Hecht

2019 Show Issue

Other Beilstein-Institut Open Science Activities

Keep Informed

RSS Feed

Subscribe to our Latest Articles RSS Feed.

Subscribe

Follow the Beilstein-Institut

LinkedIn

Twitter: @BeilsteinInst