Activation of cryptic metabolite production through gene disruption: Dimethyl furan-2,4-dicarboxylate produced by Streptomyces sahachiroi

Dinesh Simkhada, Huitu Zhang, Shogo Mori, Howard Williams and Coran M. H. Watanabe

Beilstein J. Org. Chem. 2013, 9, 1768–1773. https://doi.org/10.3762/bjoc.9.205

Supporting Information

Supporting Information File 1: Details on genetic knockout, Southern blot analysis, LC–MS analysis and NMR data.
Format: PDF Size: 917.2 KB Download

References

Article Citation
Download RIS (Reference Manager) Download BIB (BIBTEX)
Cited References
Download RIS (Reference Manager) Download BIB (BIBTEX)
Back To Article

Article is part of the issue

Natural products in synthesis and biosynthesis

Jeroen S. Dickschat

Latest Articles

Continuous flow synthesis of azobenzenes via Baeyer–Mills reaction

  1. Jan H. Griwatz,
  2. Anne Kunz and
  3. Hermann A. Wegner
  • Full Research Paper
  • Published 30 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 781–787, doi:10.3762/bjoc.18.78

Synthesis of bis-spirocyclic derivatives of 3-azabicyclo[3.1.0]hexane via cyclopropene cycloadditions to the stable azomethine ylide derived from Ruhemann's purple

  1. Alexander S. Filatov,
  2. Olesya V. Khoroshilova,
  3. Anna G. Larina,
  4. Vitali M. Boitsov and
  5. Alexander V. Stepakov
  • Full Research Paper
  • Published 29 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 769–780, doi:10.3762/bjoc.18.77

Synthesis of odorants in flow and their applications in perfumery

  1. Merlin Kleoff,
  2. Paul Kiler and
  3. Philipp Heretsch
  • Review
  • Published 27 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 754–768, doi:10.3762/bjoc.18.76

Complementarity of solution and solid state mechanochemical reaction conditions demonstrated by 1,2-debromination of tricyclic imides

  1. Petar Štrbac and
  2. Davor Margetić
  • Full Research Paper
  • Published 24 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 746–753, doi:10.3762/bjoc.18.75

An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates

  1. Timur O. Zanakhov,
  2. Ekaterina E. Galenko,
  3. Mikhail S. Novikov and
  4. Alexander F. Khlebnikov
  • Full Research Paper
  • Published 23 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 738–745, doi:10.3762/bjoc.18.74

A trustworthy mechanochemical route to isocyanides

  1. Francesco Basoccu,
  2. Federico Cuccu,
  3. Federico Casti,
  4. Rita Mocci,
  5. Claudia Fattuoni and
  6. Andrea Porcheddu
  • Full Research Paper
  • Published 22 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 732–737, doi:10.3762/bjoc.18.73

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity

  1. Jamshid Amiri Moghaddam,
  2. Huijuan Guo,
  3. Karsten Willing,
  4. Thomas Wichard and
  5. Christine Beemelmanns
  • Full Research Paper
  • Published 22 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 722–731, doi:10.3762/bjoc.18.72

Structural basis for endoperoxide-forming oxygenases

  1. Takahiro Mori and
  2. Ikuro Abe
  • Review
  • Published 21 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 707–721, doi:10.3762/bjoc.18.71

Inductive heating and flow chemistry – a perfect synergy of emerging enabling technologies

  1. Conrad Kuhwald,
  2. Sibel Türkhan and
  3. Andreas Kirschning
  • Review
  • Published 20 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 688–706, doi:10.3762/bjoc.18.70

Mechanochemical halogenation of unsymmetrically substituted azobenzenes

  1. Dajana Barišić,
  2. Mario Pajić,
  3. Ivan Halasz,
  4. Darko Babić and
  5. Manda Ćurić
  • Full Research Paper
  • Published 15 Jun 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 680–687, doi:10.3762/bjoc.18.69

Latest Articles

Latest Thematic Issues

Mechanochemistry III

José G. Hernández and Lars Borchardt

New Show Issue

Platform and enabling technologies in organic synthesis

Philipp Heretsch and
Andreas Kirschning

New Show Issue

Organic TADF materials design

Eli Zysman-Colman

2021 Call Show Issue

Earth-abundant 3d metal catalysis

Lutz Ackermann

2021 Show Issue

Supramolecular approaches to mediate chemical reactivity

Carmine Gaeta, Pablo Ballester
and Qi-Qiang Wang

2021 Show Issue

New advances in asymmetric organocatalysis

Radovan Šebesta

2020 Show Issue

GlycoBioinformatics

Kiyoko F. Aoki-Kinoshita,
Frédérique Lisacek, Niclas Karlsson, 
Daniel Kolarich and Nicolle Packer

2020 Show Issue

Polymer chemistry: fundamentals and applications

Bernhard V. K. J. Schmidt

2020 Show Issue

Molecular recognition

Jochen Niemeyer, Thomas Schrader and Ivo Piantanida

2020 Show Issue
Browse all Thematic Issues

Other Beilstein-Institut Open Science Activities

Logo
Logo
Logo
Logo

Keep Informed

RSS Feed

Subscribe to our Latest Articles RSS Feed.

Subscribe

Follow the Beilstein-Institut

LinkedIn

Twitter: @BeilsteinInst