One-pot sequential synthesis of isocyanates and urea derivatives via a microwave-assisted Staudinger–aza-Wittig reaction

Scholarly Works

• Ramachandran, A.; Anitha, P.; Gnanavel, S.; Angaiah, S. Development of 1-phenyl-3-(4-(pyridin-4-ylmethyl)phenyl)urea derivatives as robust corrosion inhibitors for mild steel in 1 M HCl environment: Insight from ,molecular, experimental, and microscopic-scale modelling approaches. Journal of Environmental Chemical Engineering 2024, 12, 111648. doi:10.1016/j.jece.2023.111648
• Jhangiani, A.; Panda, V.; Sukheja, A.; Thomas, S.; Dusseja, P.; Pandya, S.; Chintakrindi, A. Toxicological Profiling of Potential Shikimate Kinase Inhibitors Against Mycobacterium tuberculosis. Alternatives to laboratory animals : ATLA 2023, 52, 10–27. doi:10.1177/02611929231217062
• Chang, W.-J.; Liew, S. Y.; Tan, S.-P. Synthesis of N,N-diethylaminopropylurea and Monosubstituted Urea Derivatives from Primary Amines and Potassium Cyanate. Letters in Organic Chemistry 2023, 20, 877–882. doi:10.2174/1570178620666230330083659
• Kassie, A. A.; Castro De la Torre, I. Y.; Remy, M. S.; Mukhopadhyay, S.; Kampf, J.; Qu, F.; Sanford, M. S. Metal Identity Effects in the Pincer Complex-Catalyzed Dehydrogenative Coupling of Formamides with Alcohols to Form Carbamates. Organometallics 2023, 42, 1030–1036. doi:10.1021/acs.organomet.3c00175
• Labiche, A.; Norlöff, M.; Feuillastre, S.; Taran, F.; Audisio, D. Continuous Flow Synthesis of Non‐Symmetrical Ureas from CO2. Asian Journal of Organic Chemistry 2023, 12. doi:10.1002/ajoc.202200640
• Jadhav, K. A.; Itage, S. V.; Bhosle, S. D.; Bhosale, R. S.; Yadav, J. S. Zinc Promoted Urea Synthesis Using Carbonyldiimidazole as Carbonyl Source and Its Application for the Synthesis of Cariprazine. European Journal of Organic Chemistry 2023, 26. doi:10.1002/ejoc.202201169
• Webster, C. S.; Balduzzi, F.; Davis, A. P. Tricyclic octaurea "Temples" for the recognition of polar molecules in water. Organic & biomolecular chemistry 2023, 21, 525–532. doi:10.1039/d2ob02061k
• Asghar, F.; Shakoor, B.; Murtaza, B.; Butler, I. S. An insight on the different synthetic routes for the facile synthesis of O/S-donor carbamide/thiocarbamide analogs and their miscellaneous pharmacodynamic applications. Journal of Sulfur Chemistry 2022, 44, 90–147. doi:10.1080/17415993.2022.2119085
• Holmin, G. P.; Hood, J. C.; Scanlon, N.; Klumpp, D. A. Phosphonium-carbenium and oxophosphonium-carbenium dications in Friedel-Crafts reactions. Tetrahedron 2022, 121, 132928. doi:10.1016/j.tet.2022.132928
• Ohata, J.; Uzoewulu, C. P. Translation of a Phosphine- and Azide-Based Reaction to Chemical Modification of Biomolecules in Ionic Liquid. Synlett 2022, 33, 1879–1883. doi:10.1055/a-1908-2066
• Wen, W.; Cao, H.; Xu, Y.; Ren, Y.; Rao, L.; Shao, X.; Chen, H.; Wu, L.; Liu, J.; Su, C.; Peng, C.; Huang, Y.; Wan, J. N-Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction. Journal of medicinal chemistry 2022, 65, 9126–9143. doi:10.1021/acs.jmedchem.2c00336
• Santana, J. S.; Cardoso, E. S.; Triboni, E. R.; Politi, M. J. Polyureas Versatile Polymers for New Academic and Technological Applications. Polymers 2021, 13, 4393. doi:10.3390/polym13244393
• Huke, C. D.; Taylor, L. J.; Argent, S. P.; Kays, D. L. Catalyst-free Hydrophosphinylation of Isocyanates and Isothiocyanates under Low-Added-Solvent Conditions. ACS Sustainable Chemistry & Engineering 2021, 9, 10704–10709. doi:10.1021/acssuschemeng.1c02907
• Ronchetti, R.; Moroni, G.; Carotti, A.; Gioiello, A.; Camaioni, E. Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis. RSC medicinal chemistry 2021, 12, 1046–1064. doi:10.1039/d1md00058f
• Matinkhoo, K.; Wong, A. A. W. L.; Hambira, C. M.; Kato, B.; Wei, C.; Müller, C.; Hechler, T.; Braun, A.; Gallo, F.; Pahl, A.; Perrin, D. M. Design, Synthesis, and Biochemical Evaluation of Alpha-Amanitin Derivatives Containing Analogs of the trans-Hydroxyproline Residue for Potential Use in Antibody-Drug Conjugates. Chemistry (Weinheim an der Bergstrasse, Germany) 2021, 27, 10282–10292. doi:10.1002/chem.202101373
• Kennedy-Ellis, J. J.; Boldt, E. D.; Chemler, S. R. Synthesis of Benzylureas and Related Amine Derivatives via Copper-Catalyzed Three-Component Carboamination of Styrenes. Organic letters 2020, 22, 8365–8369. doi:10.1021/acs.orglett.0c02988
• Davies, J. A.; Bull, F. M.; Walker, P. D.; Weir, A. N. M.; Lavigne, R.; Masschelein, J.; Simpson, T. J.; Race, P. R.; Crump, M. P.; Willis, C. L. Total Synthesis of Kalimantacin A. Organic letters 2020, 22, 6349–6353. doi:10.1021/acs.orglett.0c02190
• Hai, T. A. P.; De Backer, L. J.; Cosford, N. D. P.; Burkart, M. D. Preparation of Mono- and Diisocyanates in Flow from Renewable Carboxylic Acids. Organic Process Research & Development 2020, 24, 2342–2346. doi:10.1021/acs.oprd.0c00167
• Luchowska-Stańska, U.; Morgan, D.; Yarwood, S. J.; Barker, G. Selective small-molecule EPAC activators. Biochemical Society transactions 2019, 47, 1415–1427. doi:10.1042/bst20190254
• Gómez, A. M.; Lopez, J. C. Carbohydrates and BODIPYs: access to bioconjugatable and water-soluble BODIPYs. Pure and Applied Chemistry 2019, 91, 1073–1083. doi:10.1515/pac-2019-0204

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