2 article(s) from Christoffers, Jens
Graphical Abstract
Figure 1: Bifunctional DAT as a cross-linker for proteins. The compound is a turn-on-probe, i.e., the fluores...
Scheme 1: Preparation of DAT–ALA conjugate 3 with fluorinated benzyl residue.
Scheme 2: Preparation of conjugate 7 consisting of fluorinated DAT and ALA moieties with an additional propyl...
Figure 2: High-resolution XPS of SAM 3.
Figure 3: High-resolution XPS of SAM 7.
Graphical Abstract
Scheme 1: Target structure of this synthetic study and two previous approaches.
Scheme 2: Preparation of isopropylidene protected ribose 9 along a new, modified route. Reagents and conditio...
Scheme 3: Final four steps of the synthesis. Reagents and conditions: (a) 1. 4.5 equiv NH2OH·HCl, 4 equiv NaH...