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1 article(s) from Hirai, Yumi

Cholesterol lowering effects of mono-lactose-appended β-cyclodextrin in Niemann–Pick type C disease-like HepG2 cells

Keiichi Motoyama,
Yumi Hirai,
Rena Nishiyama,
Yuki Maeda,
Taishi Higashi,
Yoichi Ishitsuka,
Yuki Kondo,
Tetsumi Irie,
Takumi Era and
Hidetoshi Arima

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Published 03 Nov 2015

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1. Graphical Abstract
2. Figure 1: Preparation scheme of Lac-β-CyD.
  
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3. Figure 2: MALDI–TOF MS (A) and ¹H NMR (B) spectra of Lac-β-CyD.
  
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4. Figure 3: Cytotoxic activity of β-CyDs in U18666A-treated HepG2 cells after treatment for 24 h. U18666A-treat...
  
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5. Figure 4: Cellular association of TRITC-Lac-β-CyD in U18666A-treated HepG2 cells after treatment for 24 h. Th...
  
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6. Figure 5: Intracellular distribution of TRITC-Lac-β-CyD in U18666A-treated HepG2 cells. U18666A-treated HepG2...
  
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7. Figure 6: Effect of concentration of Lac-β-CyD on intracellular level of free form of cholesterol in U18666A-...
  
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Graphical Abstract

Beilstein J. Org. Chem. 2015, 11, 2079–2086, doi:10.3762/bjoc.11.224

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