1 article(s) from Huang, Yunqi
Anti-HIV compound containing a trifluoromethylpropargylamine moiety.
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Literature-known methods (a and b) and the here reported (c) approach for the synthesis of α-triflu...
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Substrate scope study. Reaction conditions: arylethyne 2 (0.39 mmol), imine 1 (0.3 mmol), LiHMDS (0...
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ORTEP diagram showing of the minor product of 3a.
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Mode of nucleophilic attacks A and B.
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Large-scale application of the reaction.
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Removal of the chiral auxiliary.
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Beilstein J. Org. Chem. 2020, 16, 2671–2678, doi:10.3762/bjoc.16.217
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