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Beilstein J. Org. Chem. 2025, 21, 2376–2382, doi:10.3762/bjoc.21.182
Graphical Abstract
Figure 1: Selected representative natural products and derivatives with β-lactone moiety.
Scheme 1: Previous syntheses of vibralactone (6).
Scheme 2: Retrosynthetic analysis of vibralactone (6).
Scheme 3: Synthetic study toward vibralactone (6) in the present of β-lactone.
Scheme 4: C–H insertion utilizing linear precursor 19.
Scheme 5: Construction the bicyclic skeleton of vibralactone (6) through C–H insertion.
Beilstein J. Org. Chem. 2022, 18, 1625–1628, doi:10.3762/bjoc.18.173
Figure 1: Selected representative natural products with 6-5-5 tricyclic skeleton.
Scheme 1: Retrosynthetic analysis of aberrarone (1).
Scheme 2: Synthetic study toward aberrarone (1).