3 article(s) from Mayer, Peter
Graphical Abstract
Figure 1: Atorvastatin calcium trihydrate (1) and previously published decomposition products arising from tr...
Scheme 1: Formation of novel artefacts 6 and 7 under extremely strong acidic conditions.
Figure 2: Top: Molecular structure of artefact 6. Shown here is the molecular structure of one of three indep...
Figure 3: Separation of atorvastatin (1; retention time: 5.8 min) from the four decomposition products 2 (ret...
Scheme 2: Proposed mechanism for the formation of desamidated product 7.
Scheme 3: Proposed mechanism for the formation of bridged product 6 under cyclization, isopropyl migration an...
Graphical Abstract
Figure 1: Function and inhibition of hCAII. a) hCAII (pdb: 2vva [7]) catalyzes the hydration of carbon dioxide t...
Scheme 1: Synthesis and characterization of azobenzene-containing aryl sulfonamides by different strategies. ...
Figure 2: Crystal structures for compounds 1a–i (co-solvents and/or multiple molecules in the asymmetric cell...
Figure 3: Crystal structure of hCAII bound to 1d (pdb: 5byi). a) The terminal amine of 1d is solvent-exposed,...
Figure 4: Inhibition of hCAII by electronically different azobenzene sulfonamides and AAZ. a) Endpoint measur...
Graphical Abstract
Figure 1: The chemical structures of DMP (1), 2-iodobenzoic acid (2), IBX (3) and 4.
Figure 2: ORTEP diagram (50% probability level) of 1 with numbering scheme.
Figure 3: Supramolecular structure of 1 with halogen bonds and selected hydrogen bonds.
Figure 4: Further hydrogen-bond interactions in the supramolecular structure of 1.
Figure 5: Supramolecular structure of 1 viewed along axis b.