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Beilstein J. Org. Chem. 2026, 22, 383–389, doi:10.3762/bjoc.22.26
Graphical Abstract
Figure 1: Valuable amino sulfonic acids and aminosulfones.
Figure 2: Selected approaches to aminoethylation.
Scheme 1: Pyrrolidination of β-ketosulfones. Reaction conditions: β-ketosulfones (4.0 mmol), sarcosine (1.2 e...
Scheme 2: Scope of the reaction. Reaction conditions: sulfone 1 (1.0 mmol), sarcosine (1.2 equiv), (CH2O)n (2...
Scheme 3: The presumable mechanism of the domino process.
Scheme 4: Reductive elimination of the nucleophiles.