1 article(s) from Pillaiyar, Thanigaimalai
- Full Research Paper
- Published 20 Apr 2020
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Graphical Abstract
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Figure 1: Structures of trifluoromethylated compounds and their biological activities.
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Figure 2: Synthetic approaches toward hydroxyalkylation of indole.
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Figure 3: Structures of heterocycles that did not react with ketone 2a.
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Scheme 1: Gram-scale synthesis of 2,2,2-trifluoro-1-(1H-indol-3-yl)-1-phenylethan-1-ols (3a and 3p).
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Figure 4: Recyclability of the catalytic system n-Bu4PBr/K2CO3 for the preparation of 2,2,2-trifluoro-1-(5-me...
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Scheme 2: Synthesis of trifluoromethylated unsymmetrical 3,3'- and 3,6'-DIMs (9–11).
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Scheme 3: Proposed mechanism for the preparation of 3a as an example.
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Scheme 4: Control experiments.
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