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Beilstein J. Org. Chem. 2026, 22, 205–212, doi:10.3762/bjoc.22.14
Graphical Abstract
Figure 1: Representation of the general practices for the induction of helical chirality in organic scaffolds...
Scheme 1: Asymmetric synthesis of carbohelicenes via peri-C–H functionalization.
Figure 2: Stereomodel for peri-terminal functionalization of carbohelicene. (Figure 2 was reproduced from [32] (© 2024 X....
Scheme 2: Scale-up synthesis and post-synthetic application of chiral helical product 3.
Scheme 3: Asymmetric peri-C–H functionalization of nitro-substituted oxa[5]helicenes.
Scheme 4: Scale-up synthesis and post-synthetic application of chiral helical product 8g.
Scheme 5: Post-synthetic transformation of product 8g to chiral phosphine ligand 12 and its application in Pd...
Figure 3: Stereomodel for the asymmetric peri-C–H functionalization of oxa[5]helicene. (Figure 3 was reproduced from [33]...