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Beilstein J. Org. Chem. 2015, 11, 219–227, doi:10.3762/bjoc.11.24
Graphical Abstract
Figure 1: Base pairing of TC with G (A), TA with T (B), UC with G (C) and UA with T (D).
Scheme 1: Synthesis of nucleoside TA and its corresponding phosphoramidite 5. TPS = 2,4,6-triisopropylbenzene...
Scheme 2: Synthesis of nucleoside UA and its corresponding phosphoramidite 10.
Scheme 3: Synthesis of nucleoside UC and its corresponding phosphoramidite 14.
Figure 2: EPR spectra of 14-mer DNA duplexes 5′-d(GACCTCGTAATCGTG)•5′-d(CACGATYCGAGGTC), (10 mM phosphate, 10...
Figure 3: Possible base pairing of TAH+ with C (A) and G (B) at pH 5.
Figure 4: Possible base pairing of UA and UC with C.
Figure 5: EPR spectra of 14-mer DNA duplex 5′-d(GACCTCGUAATCGTG)•5′-d(CACGATYCGAGGTC) (A), and 5′-d(GACCTCGUC...